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The map label for this gene is hflC [H]

Identifier: 126208548

GI number: 126208548

Start: 1244933

End: 1245820

Strand: Reverse

Name: hflC [H]

Synonym: APL_1076

Alternate gene names: 126208548

Gene position: 1245820-1244933 (Counterclockwise)

Preceding gene: 126208549

Following gene: 126208547

Centisome position: 54.77

GC content: 43.92

Gene sequence:

>888_bases
ATGCGTAAATTATTATTACCTATTTTATCTCTGGTTGCTTTTTTAGTGATCTCTTGTATTACGATCGTACCGGAAGGCTA
TCGCGGCATTATGTTACGTTTTAATAAAGTGCATCGCGACGCAGACCAAAAAGTGGTGGTTTATGCGCCGGGTTTACATT
TTAAAGCGCCGTTTATCGATAACTTAAAAGTGTTGGATGCGCGTATTCAAATTTTAGACGGTCAGGAAGATCGCTTCGTG
ACGGTTGAGAAAAAAGACTTATTAGTCGATTCTTACGTGAAATGGCGTATCAGTGATTTCGGTAAGTTTTATACGGCGAC
CGGTGGTGATGCGCAACGTGCTTCGGATCTTTTAAAACGTAAAGTGGGCGACCGTTTACGTTCTGAAATCGGTTCTCGTA
CGATTAAAGATATCGTATCCGGTTCTCGCGGCGAATTGATGGCAGGTGCGCAAAAAGCCGTAAATGACGGCGATGACGGT
GCCGAAAAACTCGGTATCGAAGTGGTCGATGTACGTGTGAAACAGATCAACTTACCGAATGAAGTTTCATCTTCAATTTA
TCAACGTATGCGCGCGGAACGTGCTGCGGTTGCAAGCGAACACCGCTCACAAGGTGAAGAAAAAGCCGAAATTATTCGTG
CCGAAGTAGATAAGAAAGTGGTGCTTATTGAAGCGCAAGCGAAGAAAACCGCCGAAACTTTACGCGGTGAAGGCGATGCG
CAAGCTGCAAAAATTTATGCTGACGCATTCAGCCGAGAGCCGGAGTTTTATAGCTTCGTGCGTAGCTTAAAAGCATACGA
AAACAGCTTTGCCAAAGATCAAAGCAATATGATGCTACTTAAATCGGACAGCGAATTCTTCCGCTTTATGAAAGCACCGA
CAAAATAA

Upstream 100 bases:

>100_bases
CGCCGATTGTTGTTCAGCAACCGCAAGTGATCCATCAACCGGCGCAAACCGTGCCGACTACACAAAACGAACAACCGGTA
CGTAAGGGGAGATTTTAATA

Downstream 100 bases:

>100_bases
TTGTATCCGTAAGACCCGATCTATATCGGGTCTTTAACTTTTTTATTTCTCTCTGAAACTAAAATATAGCAAGCGGTAGA
ATTTCGCTGTTTTTTAGCAA

Product: protein HflC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MRKLLLPILSLVAFLVISCITIVPEGYRGIMLRFNKVHRDADQKVVVYAPGLHFKAPFIDNLKVLDARIQILDGQEDRFV
TVEKKDLLVDSYVKWRISDFGKFYTATGGDAQRASDLLKRKVGDRLRSEIGSRTIKDIVSGSRGELMAGAQKAVNDGDDG
AEKLGIEVVDVRVKQINLPNEVSSSIYQRMRAERAAVASEHRSQGEEKAEIIRAEVDKKVVLIEAQAKKTAETLRGEGDA
QAAKIYADAFSREPEFYSFVRSLKAYENSFAKDQSNMMLLKSDSEFFRFMKAPTK

Sequences:

>Translated_295_residues
MRKLLLPILSLVAFLVISCITIVPEGYRGIMLRFNKVHRDADQKVVVYAPGLHFKAPFIDNLKVLDARIQILDGQEDRFV
TVEKKDLLVDSYVKWRISDFGKFYTATGGDAQRASDLLKRKVGDRLRSEIGSRTIKDIVSGSRGELMAGAQKAVNDGDDG
AEKLGIEVVDVRVKQINLPNEVSSSIYQRMRAERAAVASEHRSQGEEKAEIIRAEVDKKVVLIEAQAKKTAETLRGEGDA
QAAKIYADAFSREPEFYSFVRSLKAYENSFAKDQSNMMLLKSDSEFFRFMKAPTK
>Mature_295_residues
MRKLLLPILSLVAFLVISCITIVPEGYRGIMLRFNKVHRDADQKVVVYAPGLHFKAPFIDNLKVLDARIQILDGQEDRFV
TVEKKDLLVDSYVKWRISDFGKFYTATGGDAQRASDLLKRKVGDRLRSEIGSRTIKDIVSGSRGELMAGAQKAVNDGDDG
AEKLGIEVVDVRVKQINLPNEVSSSIYQRMRAERAAVASEHRSQGEEKAEIIRAEVDKKVVLIEAQAKKTAETLRGEGDA
QAAKIYADAFSREPEFYSFVRSLKAYENSFAKDQSNMMLLKSDSEFFRFMKAPTK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=313, Percent_Identity=54.3130990415335, Blast_Score=330, Evalue=8e-92,
Organism=Escherichia coli, GI1786697, Length=257, Percent_Identity=23.7354085603113, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 33129; Mature: 33129

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLLLPILSLVAFLVISCITIVPEGYRGIMLRFNKVHRDADQKVVVYAPGLHFKAPFID
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
NLKVLDARIQILDGQEDRFVTVEKKDLLVDSYVKWRISDFGKFYTATGGDAQRASDLLKR
CHHHHHHHHEEECCCCCCEEEEEHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHH
KVGDRLRSEIGSRTIKDIVSGSRGELMAGAQKAVNDGDDGAEKLGIEVVDVRVKQINLPN
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHCCEEEEEEEEECCCCH
EVSSSIYQRMRAERAAVASEHRSQGEEKAEIIRAEVDKKVVLIEAQAKKTAETLRGEGDA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEECHHHHHHHHHCCCCCH
QAAKIYADAFSREPEFYSFVRSLKAYENSFAKDQSNMMLLKSDSEFFRFMKAPTK
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHCCCCC
>Mature Secondary Structure
MRKLLLPILSLVAFLVISCITIVPEGYRGIMLRFNKVHRDADQKVVVYAPGLHFKAPFID
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
NLKVLDARIQILDGQEDRFVTVEKKDLLVDSYVKWRISDFGKFYTATGGDAQRASDLLKR
CHHHHHHHHEEECCCCCCEEEEEHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHH
KVGDRLRSEIGSRTIKDIVSGSRGELMAGAQKAVNDGDDGAEKLGIEVVDVRVKQINLPN
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHCCEEEEEEEEECCCCH
EVSSSIYQRMRAERAAVASEHRSQGEEKAEIIRAEVDKKVVLIEAQAKKTAETLRGEGDA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEECHHHHHHHHHCCCCCH
QAAKIYADAFSREPEFYSFVRSLKAYENSFAKDQSNMMLLKSDSEFFRFMKAPTK
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]