Click here to switch to the map view.

The map label for this gene is qseC [H]

Identifier: 126208536

GI number: 126208536

Start: 1232348

End: 1233724

Strand: Direct

Name: qseC [H]

Synonym: APL_1064

Alternate gene names: 126208536

Gene position: 1232348-1233724 (Clockwise)

Preceding gene: 126208535

Following gene: 126208538

Centisome position: 54.18

GC content: 42.7

Gene sequence:

>1377_bases
ATGCTTAAACGCTTTGCTAACAATAGTTTACGTTTTAGATTGATCGTTATTTTATCCGGTATCAGCCTACTCATTTGGTT
TACCGCCACAGCGATAGAATGGTTTAAATTTCGTGAAGAAATGGATAAACAATTCGATACGCAACAAGTTTTATTTGCGG
AACGACTCGCCTCTTCGAATATTATGCAAGGCTTTCATGAAATTCGCCCTCGCCATCGCCGTCACTTCTATCAAAAACAC
GTGGATGACGACGCTTTGGCGTTTGCCGTGTTTACCGAACAAGGCGATCCTATTTTCAATGACGGGCGGGACGGACAATT
TATCGAGTTCGCTCCCCACAGAGGCTTTAAAAACGTCCGCTTAATCGAACACGACGATGAAGAAGACGAAGTGGATACAT
GGCGTATTTTTTGGTTAAAACATCGAGATTTGTATATTGCCGTCGGGCAGGAAATCGACTATCGCAATAAGATCATCAAT
AAAGTGATGGCTTCAAAATTTTGGGGAGGTTTTATCGCTCTACCGCTATTGATTTTGGCGATTTGGTTTATCGTTACTCG
AGAATTAACTTCGTTACGTTCATTACAAAAACAAGTGTTAAAACGTAAACCGGATGAAACCACACCAATTCAAACGGCGC
ATTTACCCCAAGAAATTCAACCGCTTGTACAAAGTTTAAATCGTTATTTCAACCGTACTCAAACGATGTTAAGCCGAGAA
CGACGATTTACTTCCGATGCGGCGCATGAATTACGCAGCCCGTTAGCCGGCTTACGTATTCAAACGGAAATTGCCCAAAT
GACGCTGGACGATCCCGATACGCATTTAAGTGCTTTAAATAACCTAACTCACGGCATTGACCGGATTGCGCAATTAATCG
AGCAATTACTCACACTCTCTCGTTTAGAGAATTTAGAACAGCTTGATGAGCTTGAAACGATCAATTGGCAGGCATTAATC
GAACAAAATGTCAGCCAGCTTTACCCGCAAGCGGAAAGCAAGCGGTTGGAAATCTGCGCGGATTTGCAAAGCATACCGCA
AAATCAGCAAGGAAAGCCGCTACTGATCAATTTAATCTTGCGGAATTTAATTGATAATGCGATTAACTATACGCCGGAAG
GCAGTAAAATTAAGCTGACGCTGACCTCAAACGGTTTAACGATTGAAGACGACGGTTACGGAGTAAGTGATGAAGATTTG
AATAAACTCGGACAACCGTTTTATCGTCCGGTCGATCGCCCGGTTCAATCCGATAAAGATGAGAAAGGCAGCGGCTTAGG
CATTTCGATCATTAAACGTATCGTTGAGCTGCACGGTTTCTCGATGAAACTTAGCCGTAGCGAGATGGGCGGTTTAAAAG
CGGAAATTATTTTCTAA

Upstream 100 bases:

>100_bases
AGTAACGCTATGGAAGTTTATATCCATAATTTACGTAAAAAACTCGGTAAAGAATGGATCAAAACCGTACACGGCATAGG
TTATAAAATAGGAAATTCAG

Downstream 100 bases:

>100_bases
TTAAGCCGAAGAGAAAAAGACGAAGTTTTCCGCTTCGTCTTTTTTATTTATTGTACGATAAGGCGATTAACCAGCGTAAT
TACTTGCTGAATCTGCGCTG

Product: sensor protein QseC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MLKRFANNSLRFRLIVILSGISLLIWFTATAIEWFKFREEMDKQFDTQQVLFAERLASSNIMQGFHEIRPRHRRHFYQKH
VDDDALAFAVFTEQGDPIFNDGRDGQFIEFAPHRGFKNVRLIEHDDEEDEVDTWRIFWLKHRDLYIAVGQEIDYRNKIIN
KVMASKFWGGFIALPLLILAIWFIVTRELTSLRSLQKQVLKRKPDETTPIQTAHLPQEIQPLVQSLNRYFNRTQTMLSRE
RRFTSDAAHELRSPLAGLRIQTEIAQMTLDDPDTHLSALNNLTHGIDRIAQLIEQLLTLSRLENLEQLDELETINWQALI
EQNVSQLYPQAESKRLEICADLQSIPQNQQGKPLLINLILRNLIDNAINYTPEGSKIKLTLTSNGLTIEDDGYGVSDEDL
NKLGQPFYRPVDRPVQSDKDEKGSGLGISIIKRIVELHGFSMKLSRSEMGGLKAEIIF

Sequences:

>Translated_458_residues
MLKRFANNSLRFRLIVILSGISLLIWFTATAIEWFKFREEMDKQFDTQQVLFAERLASSNIMQGFHEIRPRHRRHFYQKH
VDDDALAFAVFTEQGDPIFNDGRDGQFIEFAPHRGFKNVRLIEHDDEEDEVDTWRIFWLKHRDLYIAVGQEIDYRNKIIN
KVMASKFWGGFIALPLLILAIWFIVTRELTSLRSLQKQVLKRKPDETTPIQTAHLPQEIQPLVQSLNRYFNRTQTMLSRE
RRFTSDAAHELRSPLAGLRIQTEIAQMTLDDPDTHLSALNNLTHGIDRIAQLIEQLLTLSRLENLEQLDELETINWQALI
EQNVSQLYPQAESKRLEICADLQSIPQNQQGKPLLINLILRNLIDNAINYTPEGSKIKLTLTSNGLTIEDDGYGVSDEDL
NKLGQPFYRPVDRPVQSDKDEKGSGLGISIIKRIVELHGFSMKLSRSEMGGLKAEIIF
>Mature_458_residues
MLKRFANNSLRFRLIVILSGISLLIWFTATAIEWFKFREEMDKQFDTQQVLFAERLASSNIMQGFHEIRPRHRRHFYQKH
VDDDALAFAVFTEQGDPIFNDGRDGQFIEFAPHRGFKNVRLIEHDDEEDEVDTWRIFWLKHRDLYIAVGQEIDYRNKIIN
KVMASKFWGGFIALPLLILAIWFIVTRELTSLRSLQKQVLKRKPDETTPIQTAHLPQEIQPLVQSLNRYFNRTQTMLSRE
RRFTSDAAHELRSPLAGLRIQTEIAQMTLDDPDTHLSALNNLTHGIDRIAQLIEQLLTLSRLENLEQLDELETINWQALI
EQNVSQLYPQAESKRLEICADLQSIPQNQQGKPLLINLILRNLIDNAINYTPEGSKIKLTLTSNGLTIEDDGYGVSDEDL
NKLGQPFYRPVDRPVQSDKDEKGSGLGISIIKRIVELHGFSMKLSRSEMGGLKAEIIF

Specific function: Member of a two-component regulatory system qseB/qseC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=456, Percent_Identity=38.5964912280702, Blast_Score=315, Evalue=4e-87,
Organism=Escherichia coli, GI1790551, Length=308, Percent_Identity=31.1688311688312, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1786783, Length=320, Percent_Identity=28.125, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788279, Length=242, Percent_Identity=29.7520661157025, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1790346, Length=240, Percent_Identity=27.9166666666667, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787894, Length=236, Percent_Identity=26.6949152542373, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1786600, Length=208, Percent_Identity=28.8461538461538, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1790861, Length=325, Percent_Identity=24.9230769230769, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789808, Length=286, Percent_Identity=24.8251748251748, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1789149, Length=229, Percent_Identity=27.9475982532751, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788393, Length=245, Percent_Identity=26.1224489795918, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082128, Length=226, Percent_Identity=27.4336283185841, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53004; Mature: 53004

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRFANNSLRFRLIVILSGISLLIWFTATAIEWFKFREEMDKQFDTQQVLFAERLASSN
CCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
IMQGFHEIRPRHRRHFYQKHVDDDALAFAVFTEQGDPIFNDGRDGQFIEFAPHRGFKNVR
HHHHHHHHCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCE
LIEHDDEEDEVDTWRIFWLKHRDLYIAVGQEIDYRNKIINKVMASKFWGGFIALPLLILA
EEECCCCCCCCCEEEEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
IWFIVTRELTSLRSLQKQVLKRKPDETTPIQTAHLPQEIQPLVQSLNRYFNRTQTMLSRE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
RRFTSDAAHELRSPLAGLRIQTEIAQMTLDDPDTHLSALNNLTHGIDRIAQLIEQLLTLS
HHHHHHHHHHHHCCHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLENLEQLDELETINWQALIEQNVSQLYPQAESKRLEICADLQSIPQNQQGKPLLINLIL
HHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHH
RNLIDNAINYTPEGSKIKLTLTSNGLTIEDDGYGVSDEDLNKLGQPFYRPVDRPVQSDKD
HHHHHHHCCCCCCCCEEEEEEECCCEEECCCCCCCCHHHHHHHCCHHHHHCCCCCCCCCC
EKGSGLGISIIKRIVELHGFSMKLSRSEMGGLKAEIIF
CCCCCCCHHHHHHHHHHCCCCEEECHHHHCCCEEEEEC
>Mature Secondary Structure
MLKRFANNSLRFRLIVILSGISLLIWFTATAIEWFKFREEMDKQFDTQQVLFAERLASSN
CCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
IMQGFHEIRPRHRRHFYQKHVDDDALAFAVFTEQGDPIFNDGRDGQFIEFAPHRGFKNVR
HHHHHHHHCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCE
LIEHDDEEDEVDTWRIFWLKHRDLYIAVGQEIDYRNKIINKVMASKFWGGFIALPLLILA
EEECCCCCCCCCEEEEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
IWFIVTRELTSLRSLQKQVLKRKPDETTPIQTAHLPQEIQPLVQSLNRYFNRTQTMLSRE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
RRFTSDAAHELRSPLAGLRIQTEIAQMTLDDPDTHLSALNNLTHGIDRIAQLIEQLLTLS
HHHHHHHHHHHHCCHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLENLEQLDELETINWQALIEQNVSQLYPQAESKRLEICADLQSIPQNQQGKPLLINLIL
HHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHH
RNLIDNAINYTPEGSKIKLTLTSNGLTIEDDGYGVSDEDLNKLGQPFYRPVDRPVQSDKD
HHHHHHHCCCCCCCCEEEEEEECCCEEECCCCCCCCHHHHHHHCCHHHHHCCCCCCCCCC
EKGSGLGISIIKRIVELHGFSMKLSRSEMGGLKAEIIF
CCCCCCCHHHHHHHHHHCCCCEEECHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]