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The map label for this gene is coaE [H]

Identifier: 126208352

GI number: 126208352

Start: 1016712

End: 1017350

Strand: Reverse

Name: coaE [H]

Synonym: APL_0876

Alternate gene names: 126208352

Gene position: 1017350-1016712 (Counterclockwise)

Preceding gene: 126208353

Following gene: 126208351

Centisome position: 44.73

GC content: 42.41

Gene sequence:

>639_bases
ATGAGCTATGTAGTCGGTTTAACCGGTGGAATCGGAAGTGGCAAAACGACAGTCGCAAACTTATTTGCCGAACTCGGGGT
GCCGTTAATTGATGCGGATATTGTTGCACGCCAAGTGGTTGAAAAGGGCTCTCCGCTATTGAGCAAAATTGCCGAGCATT
TCGGCGATGAGATTTTAACCTCGCAAGGTGAACTGGATCGAGGCAAGTTACGCCAAATCATCTTCCGACAGGAACAAGAG
AAAATATGGTTAAATAATTTGTTGCATCCGGCCATTCGCCAAGAGATGTTAAGCCAAATACAAGCCTGTTCCGAACCATA
TTTATTATTTGTGGTGCCGCTACTGATTGAAAATAACCTTACTGAATTTTGTGACCGAGTAATCGTGATTGATGTAGAGC
CTGCTATTCAGCTGGAACGAGCAACCAAGCGAGATCAAAGTAAGGTTGAAACGATTAAAAGCATTATGGCATCACAAGTT
AGCCGAACAGAGCGACTGCGTTATGCCGATGATGTGATTGAAAATAATTTACCGTTGGAACAGGGGCTTGAGCGTATAAA
AAAACAAGTCTTCGCCTTACACCAACAGTATTTAGATTTAGCAAAAGATAAGGAAAGCAAATGTCAGAAACTATCGTAA

Upstream 100 bases:

>100_bases
AACACTTAAAAAATTACCCTTTATTCCTTTTATTAGCTTTTCGACTTTCGTGCTAATTATTGATAAAATTTATATCTAAT
GGTTAGTATGGGAATTACAA

Downstream 100 bases:

>100_bases
ATTGTCCGACTTGCAATCAAGACGTGATTTGGAAGCCGGAAAGTAAATATCGTCCGTTTTGTAGCGAACGTTGCCAATTG
ATCGATTTGGGGGAATGGGC

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSYVVGLTGGIGSGKTTVANLFAELGVPLIDADIVARQVVEKGSPLLSKIAEHFGDEILTSQGELDRGKLRQIIFRQEQE
KIWLNNLLHPAIRQEMLSQIQACSEPYLLFVVPLLIENNLTEFCDRVIVIDVEPAIQLERATKRDQSKVETIKSIMASQV
SRTERLRYADDVIENNLPLEQGLERIKKQVFALHQQYLDLAKDKESKCQKLS

Sequences:

>Translated_212_residues
MSYVVGLTGGIGSGKTTVANLFAELGVPLIDADIVARQVVEKGSPLLSKIAEHFGDEILTSQGELDRGKLRQIIFRQEQE
KIWLNNLLHPAIRQEMLSQIQACSEPYLLFVVPLLIENNLTEFCDRVIVIDVEPAIQLERATKRDQSKVETIKSIMASQV
SRTERLRYADDVIENNLPLEQGLERIKKQVFALHQQYLDLAKDKESKCQKLS
>Mature_211_residues
SYVVGLTGGIGSGKTTVANLFAELGVPLIDADIVARQVVEKGSPLLSKIAEHFGDEILTSQGELDRGKLRQIIFRQEQEK
IWLNNLLHPAIRQEMLSQIQACSEPYLLFVVPLLIENNLTEFCDRVIVIDVEPAIQLERATKRDQSKVETIKSIMASQVS
RTERLRYADDVIENNLPLEQGLERIKKQVFALHQQYLDLAKDKESKCQKLS

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=198, Percent_Identity=32.8282828282828, Blast_Score=111, Evalue=5e-25,
Organism=Homo sapiens, GI191252795, Length=198, Percent_Identity=32.8282828282828, Blast_Score=111, Evalue=5e-25,
Organism=Escherichia coli, GI1786292, Length=202, Percent_Identity=51.980198019802, Blast_Score=201, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17554944, Length=199, Percent_Identity=34.6733668341709, Blast_Score=118, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI25143409, Length=165, Percent_Identity=28.4848484848485, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320402, Length=195, Percent_Identity=36.9230769230769, Blast_Score=103, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24644728, Length=184, Percent_Identity=30.9782608695652, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24658602, Length=168, Percent_Identity=31.547619047619, Blast_Score=80, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977
- InterPro:   IPR000764 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 23942; Mature: 23811

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYVVGLTGGIGSGKTTVANLFAELGVPLIDADIVARQVVEKGSPLLSKIAEHFGDEILT
CCEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
SQGELDRGKLRQIIFRQEQEKIWLNNLLHPAIRQEMLSQIQACSEPYLLFVVPLLIENNL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCH
TEFCDRVIVIDVEPAIQLERATKRDQSKVETIKSIMASQVSRTERLRYADDVIENNLPLE
HHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
QGLERIKKQVFALHQQYLDLAKDKESKCQKLS
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCC
>Mature Secondary Structure 
SYVVGLTGGIGSGKTTVANLFAELGVPLIDADIVARQVVEKGSPLLSKIAEHFGDEILT
CEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
SQGELDRGKLRQIIFRQEQEKIWLNNLLHPAIRQEMLSQIQACSEPYLLFVVPLLIENNL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCH
TEFCDRVIVIDVEPAIQLERATKRDQSKVETIKSIMASQVSRTERLRYADDVIENNLPLE
HHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
QGLERIKKQVFALHQQYLDLAKDKESKCQKLS
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA