Click here to switch to the map view.

The map label for this gene is rpiR [C]

Identifier: 126208186

GI number: 126208186

Start: 816312

End: 817184

Strand: Reverse

Name: rpiR [C]

Synonym: APL_0706

Alternate gene names: 126208186

Gene position: 817184-816312 (Counterclockwise)

Preceding gene: 126208187

Following gene: 126208185

Centisome position: 35.93

GC content: 40.89

Gene sequence:

>873_bases
ATGTCTGCTCGAGGTAAAATATTAGATACAATCGGTGCGTTACAAACCAGCCTGACCAAAACGGAAAAGAAAATCGCATC
GGCGATTTTGGCTCAGCCTGAAATTTTAAGTCAGAATTCTCTTTCTGAGGTTGCCAAGCAATTGGATGTCGGTGAAGCTA
CCTTTATTCGATTTTGTAGAACACTGGGTTTTAAAGGCTATACCGATTTTAAACTGGATTTGGCCATCGAATTAGCCACG
CAAGAAAAACGCAGTAATTCCATTTTTGATACGGATGTATCGGAAAGCGATACGCCGAAAGAAATTGCGGTTAAATTGCA
AAGCAGTTTAAATAATGTGATTGCGGAAACAATCAATCTATTGGATTTCCAAGAGTTGGAATATGTGGTTGAGGAATTAC
AAAAAGCGCAACGTATTTTCTTATTCGGTGTCGGATCGTCGGGGCTTACCGCAGAAGATGCCAAACATAAATTGATGCGT
ATCGGCTTACAAACCGATGCGGTTACCAATAACCACTTTATGTATATGCAGGCATCATTGTTACGTGAAGGCGATGTTGT
GATCGGTATCAGCCATTCCGGTTATTCCGACGAGGTAATCAGTGCGTTGAAAATCGCACGAAAAAATCATGCGAAAACCA
TTGCGATTACTCATCATATTCGTTCACCGATTACAAATGTGGCGGATTATGTGCTGATTAACGGTAATCGACAAGGTCAT
ATGCAAGGAGATTCGATCGGGACCAAAATGGCGCAATTGTTTGTACTTGATCTGATTTACTCGCTTTTGGTTAAAGCGGA
GCCGGAAAAATCGATTCAGCAAAAACAAAAAACTTTAGACGTAATCTTAGAACAACGCGTTCACGGTCGATAA

Upstream 100 bases:

>100_bases
TTACGAACCGCATAAACCGGGAAATGCGGTAGGCGGACAAAATAAATTACTTAAAAAACTTGTGGTGAAAGTACCTGTGA
GTTATCTATAGGAGGCGCAA

Downstream 100 bases:

>100_bases
TCGATAAATTACAAGCGGTCGAATTTGCAGAAATTTTTGATATTATGTAGTGATTTCACAAAGACCACTTAACTAAATTC
TATTAAAATCCTTGTAATTT

Product: putative HTH-type transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSARGKILDTIGALQTSLTKTEKKIASAILAQPEILSQNSLSEVAKQLDVGEATFIRFCRTLGFKGYTDFKLDLAIELAT
QEKRSNSIFDTDVSESDTPKEIAVKLQSSLNNVIAETINLLDFQELEYVVEELQKAQRIFLFGVGSSGLTAEDAKHKLMR
IGLQTDAVTNNHFMYMQASLLREGDVVIGISHSGYSDEVISALKIARKNHAKTIAITHHIRSPITNVADYVLINGNRQGH
MQGDSIGTKMAQLFVLDLIYSLLVKAEPEKSIQQKQKTLDVILEQRVHGR

Sequences:

>Translated_290_residues
MSARGKILDTIGALQTSLTKTEKKIASAILAQPEILSQNSLSEVAKQLDVGEATFIRFCRTLGFKGYTDFKLDLAIELAT
QEKRSNSIFDTDVSESDTPKEIAVKLQSSLNNVIAETINLLDFQELEYVVEELQKAQRIFLFGVGSSGLTAEDAKHKLMR
IGLQTDAVTNNHFMYMQASLLREGDVVIGISHSGYSDEVISALKIARKNHAKTIAITHHIRSPITNVADYVLINGNRQGH
MQGDSIGTKMAQLFVLDLIYSLLVKAEPEKSIQQKQKTLDVILEQRVHGR
>Mature_289_residues
SARGKILDTIGALQTSLTKTEKKIASAILAQPEILSQNSLSEVAKQLDVGEATFIRFCRTLGFKGYTDFKLDLAIELATQ
EKRSNSIFDTDVSESDTPKEIAVKLQSSLNNVIAETINLLDFQELEYVVEELQKAQRIFLFGVGSSGLTAEDAKHKLMRI
GLQTDAVTNNHFMYMQASLLREGDVVIGISHSGYSDEVISALKIARKNHAKTIAITHHIRSPITNVADYVLINGNRQGHM
QGDSIGTKMAQLFVLDLIYSLLVKAEPEKSIQQKQKTLDVILEQRVHGR

Specific function: Regulatory Protein Involved In Rpib Gene Repression. Also Involved In Als Operon Repression. [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI87082369, Length=264, Percent_Identity=28.4090909090909, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1788767, Length=275, Percent_Identity=29.4545454545455, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1788159, Length=214, Percent_Identity=32.2429906542056, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI87082130, Length=257, Percent_Identity=26.4591439688716, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 32143; Mature: 32012

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARGKILDTIGALQTSLTKTEKKIASAILAQPEILSQNSLSEVAKQLDVGEATFIRFCR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHCCCHHHHHHHHH
TLGFKGYTDFKLDLAIELATQEKRSNSIFDTDVSESDTPKEIAVKLQSSLNNVIAETINL
HHCCCCCCCEEEEEEEEEHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LDFQELEYVVEELQKAQRIFLFGVGSSGLTAEDAKHKLMRIGLQTDAVTNNHFMYMQASL
HHHHHHHHHHHHHHHHCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCEECCEEEEEEHHH
LREGDVVIGISHSGYSDEVISALKIARKNHAKTIAITHHIRSPITNVADYVLINGNRQGH
HCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCEEEECCCCCCC
MQGDSIGTKMAQLFVLDLIYSLLVKAEPEKSIQQKQKTLDVILEQRVHGR
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SARGKILDTIGALQTSLTKTEKKIASAILAQPEILSQNSLSEVAKQLDVGEATFIRFCR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHCCCHHHHHHHHH
TLGFKGYTDFKLDLAIELATQEKRSNSIFDTDVSESDTPKEIAVKLQSSLNNVIAETINL
HHCCCCCCCEEEEEEEEEHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LDFQELEYVVEELQKAQRIFLFGVGSSGLTAEDAKHKLMRIGLQTDAVTNNHFMYMQASL
HHHHHHHHHHHHHHHHCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCEECCEEEEEEHHH
LREGDVVIGISHSGYSDEVISALKIARKNHAKTIAITHHIRSPITNVADYVLINGNRQGH
HCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCEEEECCCCCCC
MQGDSIGTKMAQLFVLDLIYSLLVKAEPEKSIQQKQKTLDVILEQRVHGR
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]