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The map label for this gene is ftsK [H]

Identifier: 126208100

GI number: 126208100

Start: 703924

End: 706794

Strand: Direct

Name: ftsK [H]

Synonym: APL_0618

Alternate gene names: 126208100

Gene position: 703924-706794 (Clockwise)

Preceding gene: 126208099

Following gene: 126208101

Centisome position: 30.95

GC content: 44.34

Gene sequence:

>2871_bases
GTGATTGAACGATTAAAACCGCGATTAAAGGGTAAAGAGAATTTAATCAATCTGATGTTTATCTTACTGGGATTACTCGG
ATTATATTTAATCGTGGCATGGGCAAGCTATAGCCCGCTGGATAACGCTTGGAGTGTCGGAAGCAGCGTGACGGAACTGG
AAGTATTAAATAAGACGGGGGCTTTAGGCGCTTGGTCTATTGATTTACTTTATACTTTTTTAGGGAAAGTTGCCTTTATT
GTACCGTTTGCTTTACTCGGCATCGCCGCATATTCTCTTATATTGGGATTAGCTAAAGAATGGACGTGGAAACGTTTGCT
ATTCCGAGCCGTTAGCTTTCTATTATTTATAGCCGGTTTAGCCGGACTGTCCGGTGTGATTTTTTCAAATAGTGCTTATT
ATGTATCCGGCGGTTTTATCGGCGGAATGTTTCAGACGTTATTAGCGGATGTTATCGGACAATTCGGCGCATTATTCGTT
GCGATGATCTTTACCGCAGTAGGTTTTTATTTCTGTTCCGGACAATTATTACTGCCGCTATTAGCTCGATTTTATGACTG
GATTGTAGCAAAAGATAAAGCTAAAACGGTAAATGATAATACAGTGACGGAATTGCAACAAAATGACGAAAATCAACCGC
TTGTTGATAACGAATCGTTAAAGCATTCTTCTGTTGCAAATGAAAATACGGAACAGGAGCAATTAACCGATCTTTCGTTA
TTTAATAGACCGAATATTAGCGGATTACATAAAGAGCAAGAAATATCTGAAGATGCTTTAACTAATCCCGCTATGTTTAA
GGTGGAAAAAGAATTAGAGTTACCGAAAATTAATATGCAAGGGCAAGAGTTTTCTGTTGAATTAGCGACAAATTCAGCGG
AGGAGTATGTTGCCGACCTAGACTCGCCGACTTTACCGAAAGTTCGCTTAAATGTATCGTTAGCGGATAATTCCTATGAA
GAACCTGCGGTTAACCATGTCGAAACAAGCGAATCTCCGGAAGAAGACATCACAACCGAATTACAAGATCCGACGGTAAT
GCCTGCTTTTGTACAGGAAGTTAAACCAACCGTTCGTTTGCAATCGATAGAAGAAACCGTTTTCAAGCAAACGGAAGAAA
CCGAAACGGATTACGAGGCGGAACTAGCCAGAGAATTTGAACAGGCCGAACAAATGCGTCTGGCACAAATGGAACAGCGA
GCTAAAGCGCAAGGACTGGAGCAAGCGTTTGAGCAAATTATCAATAGCAAATCTGAAGTTGTCGTGCCAACGGTAAAAAT
GGCGAATGAATCGGAAAATGCGCTGTCCGTATCCTCGAATAAATCTCCCGACTATCCGAAAGGATACGGTAATACGTTGA
TACACCCGTTATTACAGCGAAGCCATAGCGTTGAAAAACCGACCACGCCGTTACCGACCTTAGATTTATTGGATGAAGCG
CCATGTCAAACGCAGCAAATTACCGAGCATGAGATTGTTGAAACCTCTCATCGTTTAGAAAGTGCGTTAGCCAATTATGG
GGTGAAAGCAACGGTCGAAGACGTATTGGTCGGTCCGGTTGTTACTCGTTATGAAATTAAACCGGCTGCCGGTGTAAAAG
CGGCGAAAGTAGTCGGATTAGCCAGCGACCTTGCCCGTGAATTAATGTTCAAAGCGATTCGTATTACGGAAGTAGTGCCG
GGTAAACCTTATATGGGGATTGAAACGCCGAATAAGCAACGTGAAACGGTTTGGCTTCGTGACGTATTAAACAGCGATGC
GTTTAAACACAGTAAGGCGACATTACCGATGGCACTCGGTAAAGATATTAGCGGCGAGCCGATCGTCGTCGATATGGCGA
AAATGCCGCATTTGTTGGTTGCAGGGCAAACCGGCGGCGGTAAATCGGTCGGTGTCAATACTATGATCTTGAGTTTATTG
TTTAAACTCTCGCCGGAACAAGTACGTTTTATTATGATCGACCCGAAAGTAGTCGAGCTTTCCATTTATAACGATATTCC
GCATTTATTAACGCCGGTCGTTACCGATATGAAAAAAGCGGCAAATGCGTTACGTTGGGCAGTGGAAGAAATGGAACGCC
GTTATTTATTAATCAGTCATTTAAACGTGCGTAATATCGAAGGTTATAACGATAAAATCGAACAAGCGGCGGCAATGAAC
TTTCCGATTCCCGATCCGACTTGGCGTCCGGGAGATTCAATGGATCAACTGCCGCCGGCGTTAGAAAAACTCAGCTATAT
CGTACTGATTGTGGATGAGTTCGCCGATTTAATGATGTCTGCCGGCAAAGAAGCGGAAGAGTACATTATGCGTATAGCGC
AAAAAGCACGAGCGGTCGGAATTCACTTAATTCTTGCAACGCAGCGTCCATCAACCGACGTAATTACCGGCGTGATTAAA
GCGAATATTCCGAGCCGTATCGCCTTTACCGTCGCAAGCCAAATCGACTCGCGTACCATTTTGGATGTCGGCGGTGCGGA
AGCGTTGCTAGGGCGCGGCGATATGTTGTATTCCGGTGCGGGGAGTCCGGATATTATTCGTATTCATGGTGCATTTATGA
GTGATGCGGATGTGCAACGAGTGGCGGATAACTGGCGTGCAAGAGGCAAACCGCAATATTTGGAAAGCATTGTCGCTTCC
GTCGAAGAAAGCGAAGGCACTAGTCGTGCAGACAGCGGTGCGGACGTAGATCCTCTTTTTGACGAAATCGTCGAGTTCGT
AATTGAAAGCGGCGTAACTTCGATTAGCGGTATTCAGCGCCGTTTCTCGCTCGGTTTTAACCGAGCGGCACGTATTGTTG
ATCAAATGGAAGCCCAAGGCATTATTTCCGAACAAGGTAAAAACGGAAAGCGTGAAATTTTAGCCAGATAA

Upstream 100 bases:

>100_bases
CTTTACTGCGATTACCCGGTGTGAACGATACGCGAACCTATGTCGTAATGGAAGAAGTGAAACAAACCAATTATCTGTTA
TTAAAATAAGGAGTTAATCG

Downstream 100 bases:

>100_bases
ATAGCGACATTGTCACGTTATTTTTATAAAGCAAGCGGTTGAATTTTTCCCTAAATTTGCAAACTTTAAGGAAAATTCGA
CCGCTCTTTTATTGCCGACT

Product: DNA translocase FtsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 956; Mature: 956

Protein sequence:

>956_residues
MIERLKPRLKGKENLINLMFILLGLLGLYLIVAWASYSPLDNAWSVGSSVTELEVLNKTGALGAWSIDLLYTFLGKVAFI
VPFALLGIAAYSLILGLAKEWTWKRLLFRAVSFLLFIAGLAGLSGVIFSNSAYYVSGGFIGGMFQTLLADVIGQFGALFV
AMIFTAVGFYFCSGQLLLPLLARFYDWIVAKDKAKTVNDNTVTELQQNDENQPLVDNESLKHSSVANENTEQEQLTDLSL
FNRPNISGLHKEQEISEDALTNPAMFKVEKELELPKINMQGQEFSVELATNSAEEYVADLDSPTLPKVRLNVSLADNSYE
EPAVNHVETSESPEEDITTELQDPTVMPAFVQEVKPTVRLQSIEETVFKQTEETETDYEAELAREFEQAEQMRLAQMEQR
AKAQGLEQAFEQIINSKSEVVVPTVKMANESENALSVSSNKSPDYPKGYGNTLIHPLLQRSHSVEKPTTPLPTLDLLDEA
PCQTQQITEHEIVETSHRLESALANYGVKATVEDVLVGPVVTRYEIKPAAGVKAAKVVGLASDLARELMFKAIRITEVVP
GKPYMGIETPNKQRETVWLRDVLNSDAFKHSKATLPMALGKDISGEPIVVDMAKMPHLLVAGQTGGGKSVGVNTMILSLL
FKLSPEQVRFIMIDPKVVELSIYNDIPHLLTPVVTDMKKAANALRWAVEEMERRYLLISHLNVRNIEGYNDKIEQAAAMN
FPIPDPTWRPGDSMDQLPPALEKLSYIVLIVDEFADLMMSAGKEAEEYIMRIAQKARAVGIHLILATQRPSTDVITGVIK
ANIPSRIAFTVASQIDSRTILDVGGAEALLGRGDMLYSGAGSPDIIRIHGAFMSDADVQRVADNWRARGKPQYLESIVAS
VEESEGTSRADSGADVDPLFDEIVEFVIESGVTSISGIQRRFSLGFNRAARIVDQMEAQGIISEQGKNGKREILAR

Sequences:

>Translated_956_residues
MIERLKPRLKGKENLINLMFILLGLLGLYLIVAWASYSPLDNAWSVGSSVTELEVLNKTGALGAWSIDLLYTFLGKVAFI
VPFALLGIAAYSLILGLAKEWTWKRLLFRAVSFLLFIAGLAGLSGVIFSNSAYYVSGGFIGGMFQTLLADVIGQFGALFV
AMIFTAVGFYFCSGQLLLPLLARFYDWIVAKDKAKTVNDNTVTELQQNDENQPLVDNESLKHSSVANENTEQEQLTDLSL
FNRPNISGLHKEQEISEDALTNPAMFKVEKELELPKINMQGQEFSVELATNSAEEYVADLDSPTLPKVRLNVSLADNSYE
EPAVNHVETSESPEEDITTELQDPTVMPAFVQEVKPTVRLQSIEETVFKQTEETETDYEAELAREFEQAEQMRLAQMEQR
AKAQGLEQAFEQIINSKSEVVVPTVKMANESENALSVSSNKSPDYPKGYGNTLIHPLLQRSHSVEKPTTPLPTLDLLDEA
PCQTQQITEHEIVETSHRLESALANYGVKATVEDVLVGPVVTRYEIKPAAGVKAAKVVGLASDLARELMFKAIRITEVVP
GKPYMGIETPNKQRETVWLRDVLNSDAFKHSKATLPMALGKDISGEPIVVDMAKMPHLLVAGQTGGGKSVGVNTMILSLL
FKLSPEQVRFIMIDPKVVELSIYNDIPHLLTPVVTDMKKAANALRWAVEEMERRYLLISHLNVRNIEGYNDKIEQAAAMN
FPIPDPTWRPGDSMDQLPPALEKLSYIVLIVDEFADLMMSAGKEAEEYIMRIAQKARAVGIHLILATQRPSTDVITGVIK
ANIPSRIAFTVASQIDSRTILDVGGAEALLGRGDMLYSGAGSPDIIRIHGAFMSDADVQRVADNWRARGKPQYLESIVAS
VEESEGTSRADSGADVDPLFDEIVEFVIESGVTSISGIQRRFSLGFNRAARIVDQMEAQGIISEQGKNGKREILAR
>Mature_956_residues
MIERLKPRLKGKENLINLMFILLGLLGLYLIVAWASYSPLDNAWSVGSSVTELEVLNKTGALGAWSIDLLYTFLGKVAFI
VPFALLGIAAYSLILGLAKEWTWKRLLFRAVSFLLFIAGLAGLSGVIFSNSAYYVSGGFIGGMFQTLLADVIGQFGALFV
AMIFTAVGFYFCSGQLLLPLLARFYDWIVAKDKAKTVNDNTVTELQQNDENQPLVDNESLKHSSVANENTEQEQLTDLSL
FNRPNISGLHKEQEISEDALTNPAMFKVEKELELPKINMQGQEFSVELATNSAEEYVADLDSPTLPKVRLNVSLADNSYE
EPAVNHVETSESPEEDITTELQDPTVMPAFVQEVKPTVRLQSIEETVFKQTEETETDYEAELAREFEQAEQMRLAQMEQR
AKAQGLEQAFEQIINSKSEVVVPTVKMANESENALSVSSNKSPDYPKGYGNTLIHPLLQRSHSVEKPTTPLPTLDLLDEA
PCQTQQITEHEIVETSHRLESALANYGVKATVEDVLVGPVVTRYEIKPAAGVKAAKVVGLASDLARELMFKAIRITEVVP
GKPYMGIETPNKQRETVWLRDVLNSDAFKHSKATLPMALGKDISGEPIVVDMAKMPHLLVAGQTGGGKSVGVNTMILSLL
FKLSPEQVRFIMIDPKVVELSIYNDIPHLLTPVVTDMKKAANALRWAVEEMERRYLLISHLNVRNIEGYNDKIEQAAAMN
FPIPDPTWRPGDSMDQLPPALEKLSYIVLIVDEFADLMMSAGKEAEEYIMRIAQKARAVGIHLILATQRPSTDVITGVIK
ANIPSRIAFTVASQIDSRTILDVGGAEALLGRGDMLYSGAGSPDIIRIHGAFMSDADVQRVADNWRARGKPQYLESIVAS
VEESEGTSRADSGADVDPLFDEIVEFVIESGVTSISGIQRRFSLGFNRAARIVDQMEAQGIISEQGKNGKREILAR

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=508, Percent_Identity=60.0393700787402, Blast_Score=634, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 105426; Mature: 105426

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIERLKPRLKGKENLINLMFILLGLLGLYLIVAWASYSPLDNAWSVGSSVTELEVLNKTG
CCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHCCC
ALGAWSIDLLYTFLGKVAFIVPFALLGIAAYSLILGLAKEWTWKRLLFRAVSFLLFIAGL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLSGVIFSNSAYYVSGGFIGGMFQTLLADVIGQFGALFVAMIFTAVGFYFCSGQLLLPL
HHCCCEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LARFYDWIVAKDKAKTVNDNTVTELQQNDENQPLVDNESLKHSSVANENTEQEQLTDLSL
HHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHH
FNRPNISGLHKEQEISEDALTNPAMFKVEKELELPKINMQGQEFSVELATNSAEEYVADL
CCCCCCCCCCHHHHHHHHHCCCCHHEEEHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHC
DSPTLPKVRLNVSLADNSYEEPAVNHVETSESPEEDITTELQDPTVMPAFVQEVKPTVRL
CCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHCCHHHHH
QSIEETVFKQTEETETDYEAELAREFEQAEQMRLAQMEQRAKAQGLEQAFEQIINSKSEV
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VVPTVKMANESENALSVSSNKSPDYPKGYGNTLIHPLLQRSHSVEKPTTPLPTLDLLDEA
EEEEHHHCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHCCC
PCQTQQITEHEIVETSHRLESALANYGVKATVEDVLVGPVVTRYEIKPAAGVKAAKVVGL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHH
ASDLARELMFKAIRITEVVPGKPYMGIETPNKQRETVWLRDVLNSDAFKHSKATLPMALG
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCCCCCHHHC
KDISGEPIVVDMAKMPHLLVAGQTGGGKSVGVNTMILSLLFKLSPEQVRFIMIDPKVVEL
CCCCCCCEEEEHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCEEEEE
SIYNDIPHLLTPVVTDMKKAANALRWAVEEMERRYLLISHLNVRNIEGYNDKIEQAAAMN
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHCC
FPIPDPTWRPGDSMDQLPPALEKLSYIVLIVDEFADLMMSAGKEAEEYIMRIAQKARAVG
CCCCCCCCCCCCCHHHCCHHHHHHHHHEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHEE
IHLILATQRPSTDVITGVIKANIPSRIAFTVASQIDSRTILDVGGAEALLGRGDMLYSGA
EEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCHHHHHCCCCEEECCC
GSPDIIRIHGAFMSDADVQRVADNWRARGKPQYLESIVASVEESEGTSRADSGADVDPLF
CCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
DEIVEFVIESGVTSISGIQRRFSLGFNRAARIVDQMEAQGIISEQGKNGKREILAR
HHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHCCCCCCHHHCCC
>Mature Secondary Structure
MIERLKPRLKGKENLINLMFILLGLLGLYLIVAWASYSPLDNAWSVGSSVTELEVLNKTG
CCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHCCC
ALGAWSIDLLYTFLGKVAFIVPFALLGIAAYSLILGLAKEWTWKRLLFRAVSFLLFIAGL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLSGVIFSNSAYYVSGGFIGGMFQTLLADVIGQFGALFVAMIFTAVGFYFCSGQLLLPL
HHCCCEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LARFYDWIVAKDKAKTVNDNTVTELQQNDENQPLVDNESLKHSSVANENTEQEQLTDLSL
HHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHH
FNRPNISGLHKEQEISEDALTNPAMFKVEKELELPKINMQGQEFSVELATNSAEEYVADL
CCCCCCCCCCHHHHHHHHHCCCCHHEEEHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHC
DSPTLPKVRLNVSLADNSYEEPAVNHVETSESPEEDITTELQDPTVMPAFVQEVKPTVRL
CCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHCCHHHHH
QSIEETVFKQTEETETDYEAELAREFEQAEQMRLAQMEQRAKAQGLEQAFEQIINSKSEV
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VVPTVKMANESENALSVSSNKSPDYPKGYGNTLIHPLLQRSHSVEKPTTPLPTLDLLDEA
EEEEHHHCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHCCC
PCQTQQITEHEIVETSHRLESALANYGVKATVEDVLVGPVVTRYEIKPAAGVKAAKVVGL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHH
ASDLARELMFKAIRITEVVPGKPYMGIETPNKQRETVWLRDVLNSDAFKHSKATLPMALG
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCCCCCHHHC
KDISGEPIVVDMAKMPHLLVAGQTGGGKSVGVNTMILSLLFKLSPEQVRFIMIDPKVVEL
CCCCCCCEEEEHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCEEEEE
SIYNDIPHLLTPVVTDMKKAANALRWAVEEMERRYLLISHLNVRNIEGYNDKIEQAAAMN
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHCC
FPIPDPTWRPGDSMDQLPPALEKLSYIVLIVDEFADLMMSAGKEAEEYIMRIAQKARAVG
CCCCCCCCCCCCCHHHCCHHHHHHHHHEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHEE
IHLILATQRPSTDVITGVIKANIPSRIAFTVASQIDSRTILDVGGAEALLGRGDMLYSGA
EEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCHHHHHCCCCEEECCC
GSPDIIRIHGAFMSDADVQRVADNWRARGKPQYLESIVASVEESEGTSRADSGADVDPLF
CCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
DEIVEFVIESGVTSISGIQRRFSLGFNRAARIVDQMEAQGIISEQGKNGKREILAR
HHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA