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The map label for this gene is mukF

Identifier: 126208061

GI number: 126208061

Start: 655340

End: 656671

Strand: Direct

Name: mukF

Synonym: APL_0579

Alternate gene names: 126208061

Gene position: 655340-656671 (Clockwise)

Preceding gene: 126208060

Following gene: 126208062

Centisome position: 28.81

GC content: 43.69

Gene sequence:

>1332_bases
ATGCAAAACGAATTGGCACAGACAATCCCCGAACTGATCAACTGGACGAAAGAGCGAGAATTTTCACTTTCGTTATCTTC
TGATCGCCTTGCCTTTCTCTTGGCGATTTCCATTTATAATAACGAACAAACGGACGGAGAGCTTTTAGAAAGTGATCTTA
TTGATCTTTTTCGTTATGTTTCGGAAGTATTCGACCAATCGGAAGCCACCCTTACACAACGTGCCAATAATGCGATTAAC
GATTTAGTTAAGCAGCGTTTTCTTAACCGTTTCTCCAGCGAATTTACCGAAGGTCTAGCCATTTATCGTATCACTCCGTT
AGGTGTCGGTGTGGCGGATTATTATGTGCGTCAGCGAGAGTTTTCCACTTTACGTTTATCCATTCAGCTTTCGATTGTAG
CGGACGAGATTCAGCGTGCTTCATCGGCGGCGGAAGAGGGCGGTGACGAGCGTTTTTGGCGTAATAACGTGTTTGCACCG
CTTAAATATTCGGTCGCGGAAATTTTCGACAGTATCGATCTTTCCCAACGTATGATGGATGAAAATCAACACCAAATTCG
TGAGCGAATTGCCGAACTGTTAAGTCAAAATTGGCATGAAGCGATTCTTAGTTGTGAACAATTACTGGACGAAACCTCGG
GTAATTTACGTGAGTTACAAGATACGCTTAATGCGGCAGGTGACAAGTTACAGGCACAATTACTGCGTATTCAAAGCTGC
TTGATCGGGCGAGATGATTTGGATTTTGTCGATCAACTGATTGTCAATCTGCAAAACAAATTAGACCGCATCATTAGCTG
GGGACAACAAGCGATTGACCTGTGGATCGGTTATGATCGTCACGTACATAAATTTATTCGTACGGCGATTGATATGGATA
AAAACCGTGTATTCGGTCAGCGTTTACGCCAATCTATTCAAGATTATTTCAAGTGCGCCTTGGTTACTTTATACTGCGAA
GCGGAATCGCTATTAGATCTGCGTGACGATGAAACGATGCTGAATGAGGCGGAAGCGGTCGGTGAATTACCGAGTGAGTT
GGAATATGAATCGCTTTCGGATGTTCAAGAACAAATTATCAGCGTAATGCAAGCGCATTTAGCACCGTTTAGAGCAGAAG
GTAAACCTATCGATCTCGGTGCGGTATTGCGAGAGCAACTTGCGCTTTATCCGCAATCTCGTCATTTTGATGTGGCTCGA
ATTATTGTGGATCAAGCGGTAAAACTCGGTATGGCAAGCCTCGATAGCCAAGCGGTTTATCCTGAATGGCAAGCAATTAA
TGATAAGGGTGCGGAAGTTCAGGCGAACGTAATCGACCAATATAACAAATAG

Upstream 100 bases:

>100_bases
CTTTGCGGAATTTGACCGCTTCTTTTTTTGATTTCGTTCCTATTTGATTCACATTCCTGTACAATAAAAGCCATTTTTCA
TCAACAAACGACAAAGCTGT

Downstream 100 bases:

>100_bases
TAGGGTGGGGAAAGTCCCACCATTGGAAAAACAGAAAGTTTAATGGTAGGCAGGAATGCCTGCCCTACGAGAGTAAAATA
TGACAGAGCAAATTCAAGAC

Product: condesin subunit F

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MQNELAQTIPELINWTKEREFSLSLSSDRLAFLLAISIYNNEQTDGELLESDLIDLFRYVSEVFDQSEATLTQRANNAIN
DLVKQRFLNRFSSEFTEGLAIYRITPLGVGVADYYVRQREFSTLRLSIQLSIVADEIQRASSAAEEGGDERFWRNNVFAP
LKYSVAEIFDSIDLSQRMMDENQHQIRERIAELLSQNWHEAILSCEQLLDETSGNLRELQDTLNAAGDKLQAQLLRIQSC
LIGRDDLDFVDQLIVNLQNKLDRIISWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRVFGQRLRQSIQDYFKCALVTLYCE
AESLLDLRDDETMLNEAEAVGELPSELEYESLSDVQEQIISVMQAHLAPFRAEGKPIDLGAVLREQLALYPQSRHFDVAR
IIVDQAVKLGMASLDSQAVYPEWQAINDKGAEVQANVIDQYNK

Sequences:

>Translated_443_residues
MQNELAQTIPELINWTKEREFSLSLSSDRLAFLLAISIYNNEQTDGELLESDLIDLFRYVSEVFDQSEATLTQRANNAIN
DLVKQRFLNRFSSEFTEGLAIYRITPLGVGVADYYVRQREFSTLRLSIQLSIVADEIQRASSAAEEGGDERFWRNNVFAP
LKYSVAEIFDSIDLSQRMMDENQHQIRERIAELLSQNWHEAILSCEQLLDETSGNLRELQDTLNAAGDKLQAQLLRIQSC
LIGRDDLDFVDQLIVNLQNKLDRIISWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRVFGQRLRQSIQDYFKCALVTLYCE
AESLLDLRDDETMLNEAEAVGELPSELEYESLSDVQEQIISVMQAHLAPFRAEGKPIDLGAVLREQLALYPQSRHFDVAR
IIVDQAVKLGMASLDSQAVYPEWQAINDKGAEVQANVIDQYNK
>Mature_443_residues
MQNELAQTIPELINWTKEREFSLSLSSDRLAFLLAISIYNNEQTDGELLESDLIDLFRYVSEVFDQSEATLTQRANNAIN
DLVKQRFLNRFSSEFTEGLAIYRITPLGVGVADYYVRQREFSTLRLSIQLSIVADEIQRASSAAEEGGDERFWRNNVFAP
LKYSVAEIFDSIDLSQRMMDENQHQIRERIAELLSQNWHEAILSCEQLLDETSGNLRELQDTLNAAGDKLQAQLLRIQSC
LIGRDDLDFVDQLIVNLQNKLDRIISWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRVFGQRLRQSIQDYFKCALVTLYCE
AESLLDLRDDETMLNEAEAVGELPSELEYESLSDVQEQIISVMQAHLAPFRAEGKPIDLGAVLREQLALYPQSRHFDVAR
IIVDQAVKLGMASLDSQAVYPEWQAINDKGAEVQANVIDQYNK

Specific function: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid

COG id: COG3006

COG function: function code D; Uncharacterized protein involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm, nucleoid. Note=Restricted to the nucleoid region (By similarity)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mukF family

Homologues:

Organism=Escherichia coli, GI1787152, Length=439, Percent_Identity=62.1867881548975, Blast_Score=582, Evalue=1e-167,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MUKF_ACTP2 (A3MZU5)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053286.1
- ProteinModelPortal:   A3MZU5
- SMR:   A3MZU5
- STRING:   A3MZU5
- GeneID:   4849076
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_0579
- eggNOG:   COG3006
- HOGENOM:   HBG296836
- OMA:   NRFSSEF
- PhylomeDB:   A3MZU5
- ProtClustDB:   PRK05260
- BioCyc:   APLE416269:APL_0579-MONOMER
- GO:   GO:0005737
- GO:   GO:0009295
- HAMAP:   MF_01803
- InterPro:   IPR005582
- PIRSF:   PIRSF018282

Pfam domain/function: PF03882 KicB

EC number: NA

Molecular weight: Translated: 50767; Mature: 50767

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNELAQTIPELINWTKEREFSLSLSSDRLAFLLAISIYNNEQTDGELLESDLIDLFRYV
CCCHHHHHHHHHHCCCCCCCEEEECCCCCEEHHHEEHHHCCCCCHHHHHHHHHHHHHHHH
SEVFDQSEATLTQRANNAINDLVKQRFLNRFSSEFTEGLAIYRITPLGVGVADYYVRQRE
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHH
FSTLRLSIQLSIVADEIQRASSAAEEGGDERFWRNNVFAPLKYSVAEIFDSIDLSQRMMD
HCEEEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHC
ENQHQIRERIAELLSQNWHEAILSCEQLLDETSGNLRELQDTLNAAGDKLQAQLLRIQSC
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIGRDDLDFVDQLIVNLQNKLDRIISWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRVFGQ
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHH
RLRQSIQDYFKCALVTLYCEAESLLDLRDDETMLNEAEAVGELPSELEYESLSDVQEQII
HHHHHHHHHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHCCCHHCCHHHHHHHHHHHH
SVMQAHLAPFRAEGKPIDLGAVLREQLALYPQSRHFDVARIIVDQAVKLGMASLDSQAVY
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
PEWQAINDKGAEVQANVIDQYNK
CCHHCCCCCCCEEHHHHHHCCCC
>Mature Secondary Structure
MQNELAQTIPELINWTKEREFSLSLSSDRLAFLLAISIYNNEQTDGELLESDLIDLFRYV
CCCHHHHHHHHHHCCCCCCCEEEECCCCCEEHHHEEHHHCCCCCHHHHHHHHHHHHHHHH
SEVFDQSEATLTQRANNAINDLVKQRFLNRFSSEFTEGLAIYRITPLGVGVADYYVRQRE
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHH
FSTLRLSIQLSIVADEIQRASSAAEEGGDERFWRNNVFAPLKYSVAEIFDSIDLSQRMMD
HCEEEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHC
ENQHQIRERIAELLSQNWHEAILSCEQLLDETSGNLRELQDTLNAAGDKLQAQLLRIQSC
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIGRDDLDFVDQLIVNLQNKLDRIISWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRVFGQ
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHH
RLRQSIQDYFKCALVTLYCEAESLLDLRDDETMLNEAEAVGELPSELEYESLSDVQEQII
HHHHHHHHHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHCCCHHCCHHHHHHHHHHHH
SVMQAHLAPFRAEGKPIDLGAVLREQLALYPQSRHFDVARIIVDQAVKLGMASLDSQAVY
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
PEWQAINDKGAEVQANVIDQYNK
CCHHCCCCCCCEEHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA