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The map label for this gene is gntR [H]

Identifier: 126208053

GI number: 126208053

Start: 643793

End: 645193

Strand: Reverse

Name: gntR [H]

Synonym: APL_0571

Alternate gene names: 126208053

Gene position: 645193-643793 (Counterclockwise)

Preceding gene: 126208056

Following gene: 126208050

Centisome position: 28.37

GC content: 39.04

Gene sequence:

>1401_bases
ATGAGGTCAGAAGTGAAAAAATTAAGCTATCTACTCAATAAGCAGCAAACTACACCGCTTTATTTACAACTTTATCAGCA
AATCAAGCGGTCTATTTATAGCCAAGAATTGCAACTTGGCGATAAATTGCCGTCTAAGCGTCACCTCTGCGAATACTTAC
AAATCAGCCAAAACACGGTGGAAAGCGCCTATGCACAGCTGTTAGCGGAAGGCTATATCGAATCCAAGCCTCGCAGCGGT
TTCTTTGTCTGTTTTCAAGCTGAGCTGACTTATCCGAGTGCTAATGTCGTAAAAAATTTTATAAATTCGACCGCTTCTAC
AGAGTATGAGATCGATTTCAACTCAAATAAAATCGATAGCCAATCTTTTCCATTGAATCGTTGGAAAAAGTGTGCCAATT
GGACAAATAAAGATTTTTTAAATATGGGCGATAAGCAAGGTGATCTCAATTTACGCCAACAGATCTCCCAATATTTATTG
GCCTCACGTGGAGTAAATTGCGAACCGGAACAAATCGTAATTGGGGCGGGCGTAGAAAGCTGCTTACAGCAATTGATTTT
ATTATTTCAACAGCTCAATCCTGCTATGAATTGGGCAATGGAATCTTACGGTTATCCTACGGTAGAAAAATTATTGAATC
TCTATCAAAAGCCAATTTTTAAAATGCCGTTCAGCTCGGAAAACTATCAGCTGGACATTCCTTTCTTGGAACAAAATCGA
ATTAACGTCGCTTATCTGACCCCCTCACACTTATATCCGTTCGGTCACATTTTAACCATCGGACAACGCCAACAATTACT
CGAATGGGCGGCAGCACAAGACGGACGCTATATTATTGAGGACGACTACGACAGTGAATTCCGCTACACCGGCAAGCCGA
TTCCGTCGTTACAAAGTTTAGACCGACAAGATAAAGTGATCTATTTGGGATCGTTTTCTAAATTACTTATGCCCTCACTG
CGAATTACGTTTTTAGTGTTACCTCGCAATTTATTGAGAGAATATCAAAAGTATTGTGAATTTTTTAATGCCTCGGTTTC
TCGCTTAGAACAGCAACGTTTAGCCAAATTTATTCAATCCGGAGAATTTGAAAAACATATTAATCGAATGAGAAAAATCT
ACCGCCGTAAAATGGAGTTATTATGTGAGCTACTCTCACCTTATACCAAACAAATTAACTATTACGGCGAACATTCCGGC
TTCTATTTGCTGATTGAATTATTAAACGAAACAAGAACGTTAGATCAATTAGTCGAACTGGCAAAAGCACAGAAAATTAA
GGTCTATCCGATTCATCACCAACAACGCAGATTATTTAGTTTAGGATTCGGACATTTGTCGGAAGAACAACTTCGGGAAG
GATTAGACAAGTTGCTATATTGTTGGGGTATTGCTTGCTAA

Upstream 100 bases:

>100_bases
AAAATTTTGGTCATATTAATTTCCTTCTTGTTGATGTGAAAATGATGGCTATTTTTATTTCAAACAGATATGATTAAAAG
CATCAATTTAATAAATATTA

Downstream 100 bases:

>100_bases
CAAGCGGTCAAATTTTACAATTTTTTTGCAAAAATAAAGGCACGTAAACACGTGCCTTTTTCTTCATTCAGCAAAGATTA
GAAATCTAATAATTCTTTTT

Product: HTH-type transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MRSEVKKLSYLLNKQQTTPLYLQLYQQIKRSIYSQELQLGDKLPSKRHLCEYLQISQNTVESAYAQLLAEGYIESKPRSG
FFVCFQAELTYPSANVVKNFINSTASTEYEIDFNSNKIDSQSFPLNRWKKCANWTNKDFLNMGDKQGDLNLRQQISQYLL
ASRGVNCEPEQIVIGAGVESCLQQLILLFQQLNPAMNWAMESYGYPTVEKLLNLYQKPIFKMPFSSENYQLDIPFLEQNR
INVAYLTPSHLYPFGHILTIGQRQQLLEWAAAQDGRYIIEDDYDSEFRYTGKPIPSLQSLDRQDKVIYLGSFSKLLMPSL
RITFLVLPRNLLREYQKYCEFFNASVSRLEQQRLAKFIQSGEFEKHINRMRKIYRRKMELLCELLSPYTKQINYYGEHSG
FYLLIELLNETRTLDQLVELAKAQKIKVYPIHHQQRRLFSLGFGHLSEEQLREGLDKLLYCWGIAC

Sequences:

>Translated_466_residues
MRSEVKKLSYLLNKQQTTPLYLQLYQQIKRSIYSQELQLGDKLPSKRHLCEYLQISQNTVESAYAQLLAEGYIESKPRSG
FFVCFQAELTYPSANVVKNFINSTASTEYEIDFNSNKIDSQSFPLNRWKKCANWTNKDFLNMGDKQGDLNLRQQISQYLL
ASRGVNCEPEQIVIGAGVESCLQQLILLFQQLNPAMNWAMESYGYPTVEKLLNLYQKPIFKMPFSSENYQLDIPFLEQNR
INVAYLTPSHLYPFGHILTIGQRQQLLEWAAAQDGRYIIEDDYDSEFRYTGKPIPSLQSLDRQDKVIYLGSFSKLLMPSL
RITFLVLPRNLLREYQKYCEFFNASVSRLEQQRLAKFIQSGEFEKHINRMRKIYRRKMELLCELLSPYTKQINYYGEHSG
FYLLIELLNETRTLDQLVELAKAQKIKVYPIHHQQRRLFSLGFGHLSEEQLREGLDKLLYCWGIAC
>Mature_466_residues
MRSEVKKLSYLLNKQQTTPLYLQLYQQIKRSIYSQELQLGDKLPSKRHLCEYLQISQNTVESAYAQLLAEGYIESKPRSG
FFVCFQAELTYPSANVVKNFINSTASTEYEIDFNSNKIDSQSFPLNRWKKCANWTNKDFLNMGDKQGDLNLRQQISQYLL
ASRGVNCEPEQIVIGAGVESCLQQLILLFQQLNPAMNWAMESYGYPTVEKLLNLYQKPIFKMPFSSENYQLDIPFLEQNR
INVAYLTPSHLYPFGHILTIGQRQQLLEWAAAQDGRYIIEDDYDSEFRYTGKPIPSLQSLDRQDKVIYLGSFSKLLMPSL
RITFLVLPRNLLREYQKYCEFFNASVSRLEQQRLAKFIQSGEFEKHINRMRKIYRRKMELLCELLSPYTKQINYYGEHSG
FYLLIELLNETRTLDQLVELAKAQKIKVYPIHHQQRRLFSLGFGHLSEEQLREGLDKLLYCWGIAC

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787710, Length=446, Percent_Identity=27.5784753363229, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1790797, Length=412, Percent_Identity=26.6990291262136, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54620; Mature: 54620

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSEVKKLSYLLNKQQTTPLYLQLYQQIKRSIYSQELQLGDKLPSKRHLCEYLQISQNTV
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ESAYAQLLAEGYIESKPRSGFFVCFQAELTYPSANVVKNFINSTASTEYEIDFNSNKIDS
HHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCCC
QSFPLNRWKKCANWTNKDFLNMGDKQGDLNLRQQISQYLLASRGVNCEPEQIVIGAGVES
CCCCHHHHHHHHCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCHHH
CLQQLILLFQQLNPAMNWAMESYGYPTVEKLLNLYQKPIFKMPFSSENYQLDIPFLEQNR
HHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHCCCEECCCCCCCEEEECCEECCCC
INVAYLTPSHLYPFGHILTIGQRQQLLEWAAAQDGRYIIEDDYDSEFRYTGKPIPSLQSL
EEEEEECCCCCCCCHHHEECCHHHHHHHHHHCCCCCEEEECCCCCCCEECCCCCCCHHHC
DRQDKVIYLGSFSKLLMPSLRITFLVLPRNLLREYQKYCEFFNASVSRLEQQRLAKFIQS
CCCCCEEEEECCHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GEFEKHINRMRKIYRRKMELLCELLSPYTKQINYYGEHSGFYLLIELLNETRTLDQLVEL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
AKAQKIKVYPIHHQQRRLFSLGFGHLSEEQLREGLDKLLYCWGIAC
HHCCCEEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRSEVKKLSYLLNKQQTTPLYLQLYQQIKRSIYSQELQLGDKLPSKRHLCEYLQISQNTV
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ESAYAQLLAEGYIESKPRSGFFVCFQAELTYPSANVVKNFINSTASTEYEIDFNSNKIDS
HHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCCC
QSFPLNRWKKCANWTNKDFLNMGDKQGDLNLRQQISQYLLASRGVNCEPEQIVIGAGVES
CCCCHHHHHHHHCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCHHH
CLQQLILLFQQLNPAMNWAMESYGYPTVEKLLNLYQKPIFKMPFSSENYQLDIPFLEQNR
HHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHCCCEECCCCCCCEEEECCEECCCC
INVAYLTPSHLYPFGHILTIGQRQQLLEWAAAQDGRYIIEDDYDSEFRYTGKPIPSLQSL
EEEEEECCCCCCCCHHHEECCHHHHHHHHHHCCCCCEEEECCCCCCCEECCCCCCCHHHC
DRQDKVIYLGSFSKLLMPSLRITFLVLPRNLLREYQKYCEFFNASVSRLEQQRLAKFIQS
CCCCCEEEEECCHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GEFEKHINRMRKIYRRKMELLCELLSPYTKQINYYGEHSGFYLLIELLNETRTLDQLVEL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
AKAQKIKVYPIHHQQRRLFSLGFGHLSEEQLREGLDKLLYCWGIAC
HHCCCEEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]