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The map label for this gene is tadA [H]

Identifier: 126208056

GI number: 126208056

Start: 646816

End: 647385

Strand: Reverse

Name: tadA [H]

Synonym: APL_0574

Alternate gene names: 126208056

Gene position: 647385-646816 (Counterclockwise)

Preceding gene: 126208057

Following gene: 126208053

Centisome position: 28.46

GC content: 42.46

Gene sequence:

>570_bases
TTGCTATTAGAACAAGCGGTTAGCTTTTTTCTCTTTTTTGCAATTATGTTTATCAAACCTCAAATCACGCAATGTTCTCT
TACCATTTCGGAACAAGATATCCATTTTATGCGGTATGCGTTGGAATTAGCGGATCGTGCCGAAGCGATAGGTGAAATTC
CGGTTGGTGCGGTATTGGTTGATCAAGAAGGCAACATTATCGGCGAAGGCTGGAATCAAGTGATTCAATTGTCCGATCCT
AGTGCGCATGCGGAAATGCTTGCGATACGTCAAGCGGGCAAAGTACAACGCAATTATCGCTTATTAGACTGTACGCTTTA
TGTCACTTTAGAACCTTGTACAATGTGTGCCGGTGCGATTTTACATAGCCGCTTACGCCGTTTAGTGTTTGGCGCAAGCG
ATTATAAAACCGGAGCTATCGGCTCTAGATTTCATCTGTTTGAAGATTATAAAATGAATCACTTTCTTGAAATTCGAGGC
GGTGTGTTAGCAGAAGAATGTAGCCAAAAAATCAGTCGATTTTTTCAACGCCGTCGCCAAGAACAAAAACGGCAGAAGCA
AGCGGTCTAA

Upstream 100 bases:

>100_bases
CGTAAAAAAGGCGGTTTTAAAGAAAAACGTTTTAATGACAAAGGTCGTGGTCGTCGCGACTAATTGATCCCGTTAATAAA
TGCCCCGATTTTGGGGCATT

Downstream 100 bases:

>100_bases
TTTCCTCGATTTTTTGCAAAATGCAATTCGATCTAAGGACACCTAAATGATGTCCTTAGATTTACGATAAAAACTACTCT
TTTAGCTGTTGTAGAAACAA

Product: tRNA-specific adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MLLEQAVSFFLFFAIMFIKPQITQCSLTISEQDIHFMRYALELADRAEAIGEIPVGAVLVDQEGNIIGEGWNQVIQLSDP
SAHAEMLAIRQAGKVQRNYRLLDCTLYVTLEPCTMCAGAILHSRLRRLVFGASDYKTGAIGSRFHLFEDYKMNHFLEIRG
GVLAEECSQKISRFFQRRRQEQKRQKQAV

Sequences:

>Translated_189_residues
MLLEQAVSFFLFFAIMFIKPQITQCSLTISEQDIHFMRYALELADRAEAIGEIPVGAVLVDQEGNIIGEGWNQVIQLSDP
SAHAEMLAIRQAGKVQRNYRLLDCTLYVTLEPCTMCAGAILHSRLRRLVFGASDYKTGAIGSRFHLFEDYKMNHFLEIRG
GVLAEECSQKISRFFQRRRQEQKRQKQAV
>Mature_189_residues
MLLEQAVSFFLFFAIMFIKPQITQCSLTISEQDIHFMRYALELADRAEAIGEIPVGAVLVDQEGNIIGEGWNQVIQLSDP
SAHAEMLAIRQAGKVQRNYRLLDCTLYVTLEPCTMCAGAILHSRLRRLVFGASDYKTGAIGSRFHLFEDYKMNHFLEIRG
GVLAEECSQKISRFFQRRRQEQKRQKQAV

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=171, Percent_Identity=29.2397660818713, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI145693172, Length=154, Percent_Identity=57.7922077922078, Blast_Score=181, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17541138, Length=152, Percent_Identity=34.8684210526316, Blast_Score=90, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17554608, Length=121, Percent_Identity=39.6694214876033, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17555996, Length=104, Percent_Identity=36.5384615384615, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6325319, Length=159, Percent_Identity=28.9308176100629, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 21604; Mature: 21604

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLEQAVSFFLFFAIMFIKPQITQCSLTISEQDIHFMRYALELADRAEAIGEIPVGAVLV
CCHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
DQEGNIIGEGWNQVIQLSDPSAHAEMLAIRQAGKVQRNYRLLDCTLYVTLEPCTMCAGAI
CCCCCEEECCCHHEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEEEEEEECHHHHHHHHH
LHSRLRRLVFGASDYKTGAIGSRFHLFEDYKMNHFLEIRGGVLAEECSQKISRFFQRRRQ
HHHHHHHHHHCCCCCCCCCCCCHHHEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
EQKRQKQAV
HHHHHHCCC
>Mature Secondary Structure
MLLEQAVSFFLFFAIMFIKPQITQCSLTISEQDIHFMRYALELADRAEAIGEIPVGAVLV
CCHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
DQEGNIIGEGWNQVIQLSDPSAHAEMLAIRQAGKVQRNYRLLDCTLYVTLEPCTMCAGAI
CCCCCEEECCCHHEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEEEEEEECHHHHHHHHH
LHSRLRRLVFGASDYKTGAIGSRFHLFEDYKMNHFLEIRGGVLAEECSQKISRFFQRRRQ
HHHHHHHHHHCCCCCCCCCCCCHHHEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
EQKRQKQAV
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]