Click here to switch to the map view.

The map label for this gene is msrB [H]

Identifier: 126207917

GI number: 126207917

Start: 489902

End: 490297

Strand: Reverse

Name: msrB [H]

Synonym: APL_0433

Alternate gene names: 126207917

Gene position: 490297-489902 (Counterclockwise)

Preceding gene: 126207925

Following gene: 126207913

Centisome position: 21.56

GC content: 46.97

Gene sequence:

>396_bases
ATGATTAAAGATATTGACGAACTAACGGAAGAACAGGTTGAAATTCTGATTAATCATGGTACGGAAATGCCATATTCCGG
CAAGTTTCTTAATGAAAATCGCATAGGAACCTACCGCTGCGCCCGTTGCCATAACGCCCTATTCCGTTCGGATACAAAAT
TTGATGCCGGCTGCGGCTGGCCTAGCTTCTACGAAGCGATTTCAGACGACGCATTACGCTATTTGGACGACTATAGTTTA
GGTCGCCACCGTACCGAAATTCGCTGCGGTAACTGCGATTCGCATATGGGGCACGTATTTAATGACGGCCCTCCGCCGAC
CGGTTTACGCTTCTGCCTGAATTCCATCGCACTCAACTTTAAATGGGATGAAACCGGTGAAGAAATTGACGGTTAA

Upstream 100 bases:

>100_bases
ATAAATTTTTTGTGATCTATGTCAAAATTTCAAAATTTGTAACGCTAAAGAGGTAAAAAAACGGTAGAATTGGAGAATAA
TTTCTATCTTAGGAGTGAAA

Downstream 100 bases:

>100_bases
TTAATTTTATAAATTAAATATCATTTTCTACATTAGGCATAAAGACAAGCGGTCGAAATTTGAAGAATTTTTGCAAATTA
TTTTCAAATTTCGACCGCTT

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MIKDIDELTEEQVEILINHGTEMPYSGKFLNENRIGTYRCARCHNALFRSDTKFDAGCGWPSFYEAISDDALRYLDDYSL
GRHRTEIRCGNCDSHMGHVFNDGPPPTGLRFCLNSIALNFKWDETGEEIDG

Sequences:

>Translated_131_residues
MIKDIDELTEEQVEILINHGTEMPYSGKFLNENRIGTYRCARCHNALFRSDTKFDAGCGWPSFYEAISDDALRYLDDYSL
GRHRTEIRCGNCDSHMGHVFNDGPPPTGLRFCLNSIALNFKWDETGEEIDG
>Mature_131_residues
MIKDIDELTEEQVEILINHGTEMPYSGKFLNENRIGTYRCARCHNALFRSDTKFDAGCGWPSFYEAISDDALRYLDDYSL
GRHRTEIRCGNCDSHMGHVFNDGPPPTGLRFCLNSIALNFKWDETGEEIDG

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=124, Percent_Identity=42.741935483871, Blast_Score=125, Evalue=7e-30,
Organism=Homo sapiens, GI301336162, Length=124, Percent_Identity=42.741935483871, Blast_Score=125, Evalue=7e-30,
Organism=Homo sapiens, GI73089054, Length=124, Percent_Identity=42.741935483871, Blast_Score=125, Evalue=7e-30,
Organism=Homo sapiens, GI37620216, Length=124, Percent_Identity=42.741935483871, Blast_Score=125, Evalue=8e-30,
Organism=Homo sapiens, GI117606353, Length=124, Percent_Identity=49.1935483870968, Blast_Score=116, Evalue=7e-27,
Organism=Escherichia coli, GI1788077, Length=124, Percent_Identity=55.6451612903226, Blast_Score=155, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI17553450, Length=116, Percent_Identity=47.4137931034483, Blast_Score=111, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI115532676, Length=116, Percent_Identity=47.4137931034483, Blast_Score=111, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6319816, Length=128, Percent_Identity=43.75, Blast_Score=103, Evalue=1e-23,
Organism=Drosophila melanogaster, GI221378664, Length=124, Percent_Identity=42.741935483871, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI221378662, Length=131, Percent_Identity=40.4580152671756, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI45553335, Length=114, Percent_Identity=43.859649122807, Blast_Score=112, Evalue=5e-26,
Organism=Drosophila melanogaster, GI21356369, Length=114, Percent_Identity=43.859649122807, Blast_Score=112, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24645799, Length=114, Percent_Identity=43.859649122807, Blast_Score=112, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24645804, Length=125, Percent_Identity=40, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24645801, Length=125, Percent_Identity=40, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 14958; Mature: 14958

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKDIDELTEEQVEILINHGTEMPYSGKFLNENRIGTYRCARCHNALFRSDTKFDAGCGW
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
PSFYEAISDDALRYLDDYSLGRHRTEIRCGNCDSHMGHVFNDGPPPTGLRFCLNSIALNF
HHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
KWDETGEEIDG
CCCCCCCCCCC
>Mature Secondary Structure
MIKDIDELTEEQVEILINHGTEMPYSGKFLNENRIGTYRCARCHNALFRSDTKFDAGCGW
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
PSFYEAISDDALRYLDDYSLGRHRTEIRCGNCDSHMGHVFNDGPPPTGLRFCLNSIALNF
HHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
KWDETGEEIDG
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]