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The map label for this gene is metX [H]

Identifier: 126207925

GI number: 126207925

Start: 497701

End: 498777

Strand: Reverse

Name: metX [H]

Synonym: APL_0441

Alternate gene names: 126207925

Gene position: 498777-497701 (Counterclockwise)

Preceding gene: 126207928

Following gene: 126207917

Centisome position: 21.93

GC content: 42.53

Gene sequence:

>1077_bases
ATGGCGCATAGCATTACCCTTTTTTCAGAAAAGCCTCTTTCTCTTATACTCGGAGGAATGCTTTCCCCGATTGATGTCGC
CTATCAAACATACGGCACGCTGAATGCGGATAAAAGTAATGTCGTCTTGCTCTGCCATGCGCTCACCGGCGATGCAGAGC
CTTATAAAAACGCACCGGAACAAGGTTGGTGGCAAGATTTTATCGGCTCGGGATTAGCTTTCGATACGGCTCGTTATTTC
TTTATTTGTTCTAACGTGCTTGGCGGGTGCAAAGGTACGACAGGTCCGTCCTCAATTAATACTAAAACAGGTAAGCCTTA
CGGAAGTCAATTTCCGATTATTACGGTGCAAGATATTGTCGAGGTACAAAAGGCTTTACTCGATACGTTAGGTATTAGCC
ATTTACATGCGGTGGTCGGCGGTTCTTTCGGTGGAATGCAAGCCACACAGTGGGGAATTAGTTATCCCGACTTTGTGAGT
AATATTATTAACTTATGTTCATCACTTACGTTAAGTGCGGAAGCGATCGGTTTTAACCATGTAATGCGCCAAGCAATTAT
CAACGATCCGCATTTTAATCATGGTGACTATTACGACGGCTTACCGCCGGATAACGGTTTAAAAATCGCTCGTATGCTCG
GTATGCTGACTTATCGTACCGATGTGCAATTGGCTCGTGCTTTCGGGCGTGAAATGAAGCAACAAACCGAAATTTGGGGC
GATTATTTTCAAGTGGAATCGTATTTGAGCTATCAGGGAGTAAAATTTTTAGATCGCTTTGATGCCAACAGCTATTTACG
CTTATTACGAGCCTTGGATTTATATGATCCGGCGTTAGGCTATGAACATGAAATTGATGCGTTAAAACGAATTAAAGCAA
ATTACACTTTGGTTGCGATTACCAGTGATCAGCTATTTAAGCAAATTGATGTACTAAAAAGTAAACAGCGTTTAGAAGCT
GCCGGCGTGCAGGTGGATTATCACGAATTTCATTCCAACTTCGGGCATGATGCTTTCTTAGTCGATTATGATTTCTTTGA
GCCGATGATTAGAAAAGGATTACAAACGGAAACCTAA

Upstream 100 bases:

>100_bases
TTGACGATTAATTTATACGTACTTTTAGGCGTTTAGACGTCTATACTGATAATAATAAGCGGTCTGATTTTCGCAAAATT
TTGTAACCTTAGGAAAAGCC

Downstream 100 bases:

>100_bases
TTTCCGTTTGCTAAAAACAGATAAAAAAAGACCGCTTGCAATAAATAACAAGCGGTCATTTTTTTATGGAATTTTTACAC
TACACGTGTGTTTGTTCAGG

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MAHSITLFSEKPLSLILGGMLSPIDVAYQTYGTLNADKSNVVLLCHALTGDAEPYKNAPEQGWWQDFIGSGLAFDTARYF
FICSNVLGGCKGTTGPSSINTKTGKPYGSQFPIITVQDIVEVQKALLDTLGISHLHAVVGGSFGGMQATQWGISYPDFVS
NIINLCSSLTLSAEAIGFNHVMRQAIINDPHFNHGDYYDGLPPDNGLKIARMLGMLTYRTDVQLARAFGREMKQQTEIWG
DYFQVESYLSYQGVKFLDRFDANSYLRLLRALDLYDPALGYEHEIDALKRIKANYTLVAITSDQLFKQIDVLKSKQRLEA
AGVQVDYHEFHSNFGHDAFLVDYDFFEPMIRKGLQTET

Sequences:

>Translated_358_residues
MAHSITLFSEKPLSLILGGMLSPIDVAYQTYGTLNADKSNVVLLCHALTGDAEPYKNAPEQGWWQDFIGSGLAFDTARYF
FICSNVLGGCKGTTGPSSINTKTGKPYGSQFPIITVQDIVEVQKALLDTLGISHLHAVVGGSFGGMQATQWGISYPDFVS
NIINLCSSLTLSAEAIGFNHVMRQAIINDPHFNHGDYYDGLPPDNGLKIARMLGMLTYRTDVQLARAFGREMKQQTEIWG
DYFQVESYLSYQGVKFLDRFDANSYLRLLRALDLYDPALGYEHEIDALKRIKANYTLVAITSDQLFKQIDVLKSKQRLEA
AGVQVDYHEFHSNFGHDAFLVDYDFFEPMIRKGLQTET
>Mature_357_residues
AHSITLFSEKPLSLILGGMLSPIDVAYQTYGTLNADKSNVVLLCHALTGDAEPYKNAPEQGWWQDFIGSGLAFDTARYFF
ICSNVLGGCKGTTGPSSINTKTGKPYGSQFPIITVQDIVEVQKALLDTLGISHLHAVVGGSFGGMQATQWGISYPDFVSN
IINLCSSLTLSAEAIGFNHVMRQAIINDPHFNHGDYYDGLPPDNGLKIARMLGMLTYRTDVQLARAFGREMKQQTEIWGD
YFQVESYLSYQGVKFLDRFDANSYLRLLRALDLYDPALGYEHEIDALKRIKANYTLVAITSDQLFKQIDVLKSKQRLEAA
GVQVDYHEFHSNFGHDAFLVDYDFFEPMIRKGLQTET

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=219, Percent_Identity=39.2694063926941, Blast_Score=166, Evalue=8e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR008220 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =2.3.1.31 [H]

Molecular weight: Translated: 39947; Mature: 39816

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHSITLFSEKPLSLILGGMLSPIDVAYQTYGTLNADKSNVVLLCHALTGDAEPYKNAPE
CCCEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCC
QGWWQDFIGSGLAFDTARYFFICSNVLGGCKGTTGPSSINTKTGKPYGSQFPIITVQDIV
CCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHH
EVQKALLDTLGISHLHAVVGGSFGGMQATQWGISYPDFVSNIINLCSSLTLSAEAIGFNH
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
VMRQAIINDPHFNHGDYYDGLPPDNGLKIARMLGMLTYRTDVQLARAFGREMKQQTEIWG
HHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DYFQVESYLSYQGVKFLDRFDANSYLRLLRALDLYDPALGYEHEIDALKRIKANYTLVAI
HHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCEEEEEE
TSDQLFKQIDVLKSKQRLEAAGVQVDYHEFHSNFGHDAFLVDYDFFEPMIRKGLQTET
CHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHCCCCCCEEEEEHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AHSITLFSEKPLSLILGGMLSPIDVAYQTYGTLNADKSNVVLLCHALTGDAEPYKNAPE
CCEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCC
QGWWQDFIGSGLAFDTARYFFICSNVLGGCKGTTGPSSINTKTGKPYGSQFPIITVQDIV
CCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHH
EVQKALLDTLGISHLHAVVGGSFGGMQATQWGISYPDFVSNIINLCSSLTLSAEAIGFNH
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
VMRQAIINDPHFNHGDYYDGLPPDNGLKIARMLGMLTYRTDVQLARAFGREMKQQTEIWG
HHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DYFQVESYLSYQGVKFLDRFDANSYLRLLRALDLYDPALGYEHEIDALKRIKANYTLVAI
HHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCEEEEEE
TSDQLFKQIDVLKSKQRLEAAGVQVDYHEFHSNFGHDAFLVDYDFFEPMIRKGLQTET
CHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHCCCCCCEEEEEHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA