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The map label for this gene is aaeR [H]

Identifier: 126175365

GI number: 126175365

Start: 3704181

End: 3705125

Strand: Reverse

Name: aaeR [H]

Synonym: Sbal_3164

Alternate gene names: 126175365

Gene position: 3705125-3704181 (Counterclockwise)

Preceding gene: 126175373

Following gene: 126175363

Centisome position: 72.26

GC content: 53.02

Gene sequence:

>945_bases
ATGGATAGACTCGAAGCGGCTAAAGTGTTTGTCACTATTGTCGAGCGCGGCAGCATGGTAAGCGCCGCTAATGCCTTAGA
TATGTCGCGTTCTATGGTGACCCGTTACTTGAGCGAAATGGAAGAATGGTCCGGTGCTAGATTGTTGCATCGTTCGACGC
GCAGCCTCAGCTTAACGCCAGCGGGTGAGCAAGTGCTGGATTACTGCCATCGACTGCTCGAATTGGCTAATGAAGTGCCG
GCGGTCAGTCATGCCGCTGTGGCTATTCCGCGCGGCTTGTTGCGTATTAGCTGCTCCCAGTTTTTGGCGCATCAGATTTT
AGCGCCCGTGGTGCGCCAATACTTAGCCAGTTATCCGCAGGCGAGTGTGAATTTCCACGTGAGTAGCCAAACCGTCGATC
TGGTCGCCGAGCGGATTGATCTGGCGATTCGCATCACCAATGAACTCGATCCCAACCTTATCGCAAGGCGCTTGGGTGAA
TGTGAATCTGTGGTGTGCGCTGCACCGAGTTACCTTGCCGCGCGCGCCGCCGTGCTGCATCCCGAAGATTTGACGCAGCA
TAATTGCTTAACCTATTCCTACTTTGGCGATGTGATGTGGCGCTTTTATCAAGCCGATGTGGCTGCGAAGCAGGCTCAGG
CGCTGAACTCTGATCCTAAGTTAAACCAAGGTCAGGCGTTTAATGTGCCTGTGAATGGCAATTTCAGCGCCAATGATTCC
ATGGTGGTGCTCAATGCCACGCTGGCAGGTGAGGGGATTGCAATGCAACCGCTGTGGGCGGCGAAACCCTATTTAGATTC
GGGTCAGTTAGTGCCTTTGTTAACTGAGTTCATGCCGCAGTCACTGGGTGTGTATGGCGTGTATCAATCCCGCAAACATA
TGCAGCCTGCACTCAGGGTGATGATGGACATGCTGGTGGCTTATTTTGCCAGTTTGAAAAGCTGA

Upstream 100 bases:

>100_bases
GCCGGATGTACTCTTAGTTATTATTCATGTGGGGCGCGAGTATGTGAGTGAGCCTTCGAGTGATTGAACGTTATTGATTG
AACGTGAGTGGAGATAAATC

Downstream 100 bases:

>100_bases
GTTGTTTTATAGAAGCTATTCGATAGCACTCCACAAAACTAGCCCATAAAAAGCATCCAATAAAAAGGAGCGCAGATCCT
TAGACCTGAGCTCCTTTTTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MDRLEAAKVFVTIVERGSMVSAANALDMSRSMVTRYLSEMEEWSGARLLHRSTRSLSLTPAGEQVLDYCHRLLELANEVP
AVSHAAVAIPRGLLRISCSQFLAHQILAPVVRQYLASYPQASVNFHVSSQTVDLVAERIDLAIRITNELDPNLIARRLGE
CESVVCAAPSYLAARAAVLHPEDLTQHNCLTYSYFGDVMWRFYQADVAAKQAQALNSDPKLNQGQAFNVPVNGNFSANDS
MVVLNATLAGEGIAMQPLWAAKPYLDSGQLVPLLTEFMPQSLGVYGVYQSRKHMQPALRVMMDMLVAYFASLKS

Sequences:

>Translated_314_residues
MDRLEAAKVFVTIVERGSMVSAANALDMSRSMVTRYLSEMEEWSGARLLHRSTRSLSLTPAGEQVLDYCHRLLELANEVP
AVSHAAVAIPRGLLRISCSQFLAHQILAPVVRQYLASYPQASVNFHVSSQTVDLVAERIDLAIRITNELDPNLIARRLGE
CESVVCAAPSYLAARAAVLHPEDLTQHNCLTYSYFGDVMWRFYQADVAAKQAQALNSDPKLNQGQAFNVPVNGNFSANDS
MVVLNATLAGEGIAMQPLWAAKPYLDSGQLVPLLTEFMPQSLGVYGVYQSRKHMQPALRVMMDMLVAYFASLKS
>Mature_314_residues
MDRLEAAKVFVTIVERGSMVSAANALDMSRSMVTRYLSEMEEWSGARLLHRSTRSLSLTPAGEQVLDYCHRLLELANEVP
AVSHAAVAIPRGLLRISCSQFLAHQILAPVVRQYLASYPQASVNFHVSSQTVDLVAERIDLAIRITNELDPNLIARRLGE
CESVVCAAPSYLAARAAVLHPEDLTQHNCLTYSYFGDVMWRFYQADVAAKQAQALNSDPKLNQGQAFNVPVNGNFSANDS
MVVLNATLAGEGIAMQPLWAAKPYLDSGQLVPLLTEFMPQSLGVYGVYQSRKHMQPALRVMMDMLVAYFASLKS

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=312, Percent_Identity=32.6923076923077, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI87081978, Length=312, Percent_Identity=29.8076923076923, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1789440, Length=306, Percent_Identity=29.7385620915033, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1787589, Length=311, Percent_Identity=26.0450160771704, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786401, Length=306, Percent_Identity=27.7777777777778, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI145693193, Length=308, Percent_Identity=26.9480519480519, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787128, Length=301, Percent_Identity=24.9169435215947, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786448, Length=292, Percent_Identity=25, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1789173, Length=269, Percent_Identity=25.6505576208178, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34606; Mature: 34606

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLEAAKVFVTIVERGSMVSAANALDMSRSMVTRYLSEMEEWSGARLLHRSTRSLSLTP
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEECCC
AGEQVLDYCHRLLELANEVPAVSHAAVAIPRGLLRISCSQFLAHQILAPVVRQYLASYPQ
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ASVNFHVSSQTVDLVAERIDLAIRITNELDPNLIARRLGECESVVCAAPSYLAARAAVLH
CCEEEEECHHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCHHHHHHCCCHHHHHHHHHCC
PEDLTQHNCLTYSYFGDVMWRFYQADVAAKQAQALNSDPKLNQGQAFNVPVNGNFSANDS
CHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCC
MVVLNATLAGEGIAMQPLWAAKPYLDSGQLVPLLTEFMPQSLGVYGVYQSRKHMQPALRV
EEEEEEEECCCCCEECCHHCCCCCCCCCCHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHH
MMDMLVAYFASLKS
HHHHHHHHHHHHCC
>Mature Secondary Structure
MDRLEAAKVFVTIVERGSMVSAANALDMSRSMVTRYLSEMEEWSGARLLHRSTRSLSLTP
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEECCC
AGEQVLDYCHRLLELANEVPAVSHAAVAIPRGLLRISCSQFLAHQILAPVVRQYLASYPQ
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ASVNFHVSSQTVDLVAERIDLAIRITNELDPNLIARRLGECESVVCAAPSYLAARAAVLH
CCEEEEECHHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCHHHHHHCCCHHHHHHHHHCC
PEDLTQHNCLTYSYFGDVMWRFYQADVAAKQAQALNSDPKLNQGQAFNVPVNGNFSANDS
CHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCC
MVVLNATLAGEGIAMQPLWAAKPYLDSGQLVPLLTEFMPQSLGVYGVYQSRKHMQPALRV
EEEEEEEECCCCCEECCHHCCCCCCCCCCHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHH
MMDMLVAYFASLKS
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]