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The map label for this gene is ydhC [C]

Identifier: 126175373

GI number: 126175373

Start: 3714821

End: 3715984

Strand: Reverse

Name: ydhC [C]

Synonym: Sbal_3172

Alternate gene names: 126175373

Gene position: 3715984-3714821 (Counterclockwise)

Preceding gene: 126175375

Following gene: 126175365

Centisome position: 72.47

GC content: 45.88

Gene sequence:

>1164_bases
ATGAATATAAAACCACCATTAGGGCTCGTTGTGCTGCTAATGATGTTTCCGCAAATTATGGAAACCATTTATAGCCCTGC
TTTGCCTAATATTGCAGAAAACTTTGCGGTGTCGGTTGCCGCTGCATCGCAAACCTTATCTGTGTACTTTATGGCCTTTG
CCATCGGCGTATTTTGCTGGGGCCGCTTAGCCGACATTATTGGTCGCCGTAAAGCTATGCTCGCGGGATTAGTCTGTTAT
GCCATTGGCTCAGCGTTAGCCTTGATGGTTAGCGACTTTAGCCTGTTGTTGATGGCCCGCGTATTGTCGGCCTTTGGCGC
GGCAGTGGGGTCTGTGATTACTCAAACTATGATGCGTGACAGTTATAGCGGAGAGGAATTAGCGAGAGTCTTTTCTGTGA
TGGGGATGTCACTTGGAATAAGCCCAGTTATCGGATTGCTATTGGGCAGTGTTCTCAGTGCGTATTGGGGTTATAAAGGT
GTGTTTGTCGCACTCATGGTCTCTGCAATCGTATTATTATTTTTGTCGGTAAAATCTTTACCCGAAACCAAACCCGCACA
TACTCAGAAAATCGCGATAGGCGAGTTAGCGATTAAGATGCTTAGTGACAGCGGGATTATTAAGAACACCTTGTTGGTGG
CGGCGTTTAATCTGATGTGGTTTAGCTACTTTTCACTGGCGCCATTTATGTTTGAGGCGCAAGGGTTATCGACGCTTGCC
TTTGGTACCAGTGGCTTACTGTTAGGCTTTGGTACATTCCTTGGCAGTTATGTTAATAAAATAATGCTGGGTCGAGGCCA
CACTGGTGCACGACTGGTTCGCTTAGCCAGTGCTATTGCACTTGTCGGTGGATTGGGGATTTGGCTGATCCAATCTACCT
TTATAGGGCTGAATAATGTTTACTTTTTAGCGCCTATGCTATTGATTGTGATTGCTTACGGTATCGCGATTCCGAACATA
CTCAGCTCGGCTTTGGCAAACTACCGCATCTATGCGGGCTCTGCTGGTGCACTCTTCGGACTGTTTTATTACATTCTGTT
GGGACTGGGTTTAGGCGGCACGGGAATCGTTCACCATTTAGGTATGGTGATTACGTTAAGTGCACTGCTTTGTGTTGGCT
TAGGTTTACATTTAGGCTTAGCCAATAAAGTAAAAAATGCTTAA

Upstream 100 bases:

>100_bases
GACACATTTGGATTTTATCTATACTGCGCCATCTTTGACAAGTATGGAGCGACATTTCGGTAAACCAACTCATTTGGATG
ACTGAAATGGACTAAAAATC

Downstream 100 bases:

>100_bases
GACGTAAATGAGAAAAAGCCAAGGCACTGAGTGCCTTGGCTTTTTGTTATGTGATTATCAACAGCTATGATTAGCGTTAG
GCTTTAGGCGTGAGTTCCTG

Product: Bcr/CflA subfamily drug resistance transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MNIKPPLGLVVLLMMFPQIMETIYSPALPNIAENFAVSVAAASQTLSVYFMAFAIGVFCWGRLADIIGRRKAMLAGLVCY
AIGSALALMVSDFSLLLMARVLSAFGAAVGSVITQTMMRDSYSGEELARVFSVMGMSLGISPVIGLLLGSVLSAYWGYKG
VFVALMVSAIVLLFLSVKSLPETKPAHTQKIAIGELAIKMLSDSGIIKNTLLVAAFNLMWFSYFSLAPFMFEAQGLSTLA
FGTSGLLLGFGTFLGSYVNKIMLGRGHTGARLVRLASAIALVGGLGIWLIQSTFIGLNNVYFLAPMLLIVIAYGIAIPNI
LSSALANYRIYAGSAGALFGLFYYILLGLGLGGTGIVHHLGMVITLSALLCVGLGLHLGLANKVKNA

Sequences:

>Translated_387_residues
MNIKPPLGLVVLLMMFPQIMETIYSPALPNIAENFAVSVAAASQTLSVYFMAFAIGVFCWGRLADIIGRRKAMLAGLVCY
AIGSALALMVSDFSLLLMARVLSAFGAAVGSVITQTMMRDSYSGEELARVFSVMGMSLGISPVIGLLLGSVLSAYWGYKG
VFVALMVSAIVLLFLSVKSLPETKPAHTQKIAIGELAIKMLSDSGIIKNTLLVAAFNLMWFSYFSLAPFMFEAQGLSTLA
FGTSGLLLGFGTFLGSYVNKIMLGRGHTGARLVRLASAIALVGGLGIWLIQSTFIGLNNVYFLAPMLLIVIAYGIAIPNI
LSSALANYRIYAGSAGALFGLFYYILLGLGLGGTGIVHHLGMVITLSALLCVGLGLHLGLANKVKNA
>Mature_387_residues
MNIKPPLGLVVLLMMFPQIMETIYSPALPNIAENFAVSVAAASQTLSVYFMAFAIGVFCWGRLADIIGRRKAMLAGLVCY
AIGSALALMVSDFSLLLMARVLSAFGAAVGSVITQTMMRDSYSGEELARVFSVMGMSLGISPVIGLLLGSVLSAYWGYKG
VFVALMVSAIVLLFLSVKSLPETKPAHTQKIAIGELAIKMLSDSGIIKNTLLVAAFNLMWFSYFSLAPFMFEAQGLSTLA
FGTSGLLLGFGTFLGSYVNKIMLGRGHTGARLVRLASAIALVGGLGIWLIQSTFIGLNNVYFLAPMLLIVIAYGIAIPNI
LSSALANYRIYAGSAGALFGLFYYILLGLGLGGTGIVHHLGMVITLSALLCVGLGLHLGLANKVKNA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=317, Percent_Identity=27.1293375394322, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87082312, Length=332, Percent_Identity=25, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788509, Length=244, Percent_Identity=27.8688524590164, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790146, Length=175, Percent_Identity=28, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 40894; Mature: 40894

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA