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The map label for this gene is hns [H]

Identifier: 126175053

GI number: 126175053

Start: 3355917

End: 3356309

Strand: Direct

Name: hns [H]

Synonym: Sbal_2848

Alternate gene names: 126175053

Gene position: 3355917-3356309 (Clockwise)

Preceding gene: 126175049

Following gene: 126175054

Centisome position: 65.45

GC content: 41.98

Gene sequence:

>393_bases
ATGAGCGAATTTTTAGAGATATTAACTCACGGCCGTCGTTTTAAAGCAGCAGTTAAAGAACTTAGCGTTGAAGAGTTACG
TGATTTAGCCGACAAATTAGATAAAATTTTAGTAGAACGCGAGTCTATGGCTGAGGAAGAAGAACAAGCCATGGCAGCTC
GTAATGCTAAGATTGAAGAAATCCGTCAACAAATGGAAGCCGTTGGTTTATCAATTGATGACTTAGGTGGCGTAGCTGTT
AAAGCAACCGCGAAGAAACGCGCTCCTCGTCCAGCTAAATACCAAATCGAAGTTGACGGTGAAATGGTTCAGTGGACTGG
CCAAGGCCGTATGCCAACCGTATTTAAGAACGAGATCAACAAAGGTCGTTCTATGGAAGATTTCTTAATCTAA

Upstream 100 bases:

>100_bases
AACGCATAATTTTATTTGATTCGAGCTATATTAGTTTCTATCATTTAGGTGTTGTTCACCATTATCCTGTATTAAAAATT
AGAGTGGGACGAAAATAGAT

Downstream 100 bases:

>100_bases
TCCAATTCGGTGTGGCGGTTCGAGTAACCAACACACATTTGCATAAAAGCTCGCGTTCATTGCGGGCTTTTTTATATCCA
TTATTGGCTGCAATCTAAAA

Product: histone family protein nucleoid-structuring protein H-NS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 130; Mature: 129

Protein sequence:

>130_residues
MSEFLEILTHGRRFKAAVKELSVEELRDLADKLDKILVERESMAEEEEQAMAARNAKIEEIRQQMEAVGLSIDDLGGVAV
KATAKKRAPRPAKYQIEVDGEMVQWTGQGRMPTVFKNEINKGRSMEDFLI

Sequences:

>Translated_130_residues
MSEFLEILTHGRRFKAAVKELSVEELRDLADKLDKILVERESMAEEEEQAMAARNAKIEEIRQQMEAVGLSIDDLGGVAV
KATAKKRAPRPAKYQIEVDGEMVQWTGQGRMPTVFKNEINKGRSMEDFLI
>Mature_129_residues
SEFLEILTHGRRFKAAVKELSVEELRDLADKLDKILVERESMAEEEEQAMAARNAKIEEIRQQMEAVGLSIDDLGGVAVK
ATAKKRAPRPAKYQIEVDGEMVQWTGQGRMPTVFKNEINKGRSMEDFLI

Specific function: Binds tightly to ds-DNA, increases its thermal stability and inhibits transcription [H]

COG id: COG2916

COG function: function code R; DNA-binding protein H-NS

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone-like protein H-NS family [H]

Homologues:

Organism=Escherichia coli, GI1789023, Length=134, Percent_Identity=35.8208955223881, Blast_Score=75, Evalue=1e-15,
Organism=Escherichia coli, GI1787489, Length=135, Percent_Identity=37.037037037037, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001801 [H]

Pfam domain/function: PF00816 Histone_HNS [H]

EC number: NA

Molecular weight: Translated: 14736; Mature: 14605

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFLEILTHGRRFKAAVKELSVEELRDLADKLDKILVERESMAEEEEQAMAARNAKIEE
CHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
IRQQMEAVGLSIDDLGGVAVKATAKKRAPRPAKYQIEVDGEMVQWTGQGRMPTVFKNEIN
HHHHHHHHCCCHHCCCCEEEEEHHHHCCCCCCCEEEEECCEEEEEECCCCCCHHHHHHHH
KGRSMEDFLI
CCCCCHHHCC
>Mature Secondary Structure 
SEFLEILTHGRRFKAAVKELSVEELRDLADKLDKILVERESMAEEEEQAMAARNAKIEE
HHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
IRQQMEAVGLSIDDLGGVAVKATAKKRAPRPAKYQIEVDGEMVQWTGQGRMPTVFKNEIN
HHHHHHHHCCCHHCCCCEEEEEHHHHCCCCCCCEEEEECCEEEEEECCCCCCHHHHHHHH
KGRSMEDFLI
CCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]