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The map label for this gene is trpB [H]

Identifier: 126174913

GI number: 126174913

Start: 3172547

End: 3173737

Strand: Direct

Name: trpB [H]

Synonym: Sbal_2705

Alternate gene names: 126174913

Gene position: 3172547-3173737 (Clockwise)

Preceding gene: 126174912

Following gene: 126174914

Centisome position: 61.87

GC content: 51.05

Gene sequence:

>1191_bases
ATGTCAAAGTTAAAGCTTAACCCTTATTTCGGCGAATACGGCGGCATGTATGTGCCACAGATTTTAGTGCCAGCCCTTAA
GCAATTAGAAACTGCCTTTGTGGAAGCGCAGGAAGATGACGACTTTAAAGCCGAATTTACCGATTTACTGAAAAACTACG
CGGGTCGCCCTACAGCACTGACCTTAACCCGCAATTTAAGCCCCAACCCTATGGTGAAAATCTACCTCAAACGAGAAGAT
TTACTCCACGGCGGCGCCCATAAAACTAACCAAGTGTTAGGCCAAGCTCTGCTTGCTAAACGCATGGGCAAAAAGGAAAT
TATTGCAGAAACCGGTGCTGGACAACACGGCGTTGCCACCGCCCTTGCCTGCGCGCTATTAGGCTTGAAATGTAAAGTCT
ATATGGGCGCGAAAGACGTTGCGCGCCAATCACCGAACGTATTTAGAATGCGGTTGATGGGCGCGGAAGTCATTCCTGTC
ACCTCTGGTTCTGCCACCTTAAAAGATGCCTGTAACGAAGCGATGCGCGACTGGTCTGGCAGCTACGAAAAGGCCCACTA
TTTGCTCGGCACGGCCGCGGGGCCACATCCGTTCCCAACCATAGTGCGTGAATTTCAACGCATTATTGGCGAAGAAACCA
AAAAGCAAATGCTAGAGCGTGAAGGTCGCCTGCCCGATGCGGTTATCGCCTGTGTGGGCGGCGGTTCCAACGCCATCGGC
ATGTTTGCTGACTTTATCGACGAGCCAAGTGTCGAACTGATTGGCGTCGAACCGGCGGGTAAAGGCATCGACACGCCAAT
GCACGGCGCGCCGCTTAAACACGGTAAGACAGGTATTTTCTTCGGTATGAAAGCGCCTTTGATGCAAAATAGCGAAGGCC
AAATCGAAGAATCCTATTCAATTTCAGCTGGATTGGACTTCCCCTCCGTTGGCCCGCAGCACGCGCATCTTAATGCCACA
GGCCGCGCCCGTTATGAATCCGCCACCGACGATGAAGCCTTGGAAGCCTTCCAACAACTGGCTCGCTGTGAAGGGATTAT
CCCCGCATTGGAATCGGCACATGCTATCGCCTATGCCGTGAAAATGGCGCGCGAGTGCACCAAAGAAACCATTTTAGTGG
TCAATCTTTCCGGTCGTGGCGACAAAGATATTTTCACCGTTTCTGACATTTTGAATGGTAAAGAGGTATAA

Upstream 100 bases:

>100_bases
GATAACGGCTCAGTTAACATTATTTATACGATTAACACCAAGACGCTGTTAGCACAATCGAAGCCACTGACAAACTGATT
GATAAGATAAGGAAAAAGGT

Downstream 100 bases:

>100_bases
CGAACATGAGTGATACATTGACTAACACTGGCCGTTACCAAGCCACCTTTGCCAAACTCAAAGCCGAAGGCCGTGGTGCT
TTTGTCCCATTCGTCACCCT

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MSKLKLNPYFGEYGGMYVPQILVPALKQLETAFVEAQEDDDFKAEFTDLLKNYAGRPTALTLTRNLSPNPMVKIYLKRED
LLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLGLKCKVYMGAKDVARQSPNVFRMRLMGAEVIPV
TSGSATLKDACNEAMRDWSGSYEKAHYLLGTAAGPHPFPTIVREFQRIIGEETKKQMLEREGRLPDAVIACVGGGSNAIG
MFADFIDEPSVELIGVEPAGKGIDTPMHGAPLKHGKTGIFFGMKAPLMQNSEGQIEESYSISAGLDFPSVGPQHAHLNAT
GRARYESATDDEALEAFQQLARCEGIIPALESAHAIAYAVKMARECTKETILVVNLSGRGDKDIFTVSDILNGKEV

Sequences:

>Translated_396_residues
MSKLKLNPYFGEYGGMYVPQILVPALKQLETAFVEAQEDDDFKAEFTDLLKNYAGRPTALTLTRNLSPNPMVKIYLKRED
LLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLGLKCKVYMGAKDVARQSPNVFRMRLMGAEVIPV
TSGSATLKDACNEAMRDWSGSYEKAHYLLGTAAGPHPFPTIVREFQRIIGEETKKQMLEREGRLPDAVIACVGGGSNAIG
MFADFIDEPSVELIGVEPAGKGIDTPMHGAPLKHGKTGIFFGMKAPLMQNSEGQIEESYSISAGLDFPSVGPQHAHLNAT
GRARYESATDDEALEAFQQLARCEGIIPALESAHAIAYAVKMARECTKETILVVNLSGRGDKDIFTVSDILNGKEV
>Mature_395_residues
SKLKLNPYFGEYGGMYVPQILVPALKQLETAFVEAQEDDDFKAEFTDLLKNYAGRPTALTLTRNLSPNPMVKIYLKREDL
LHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLGLKCKVYMGAKDVARQSPNVFRMRLMGAEVIPVT
SGSATLKDACNEAMRDWSGSYEKAHYLLGTAAGPHPFPTIVREFQRIIGEETKKQMLEREGRLPDAVIACVGGGSNAIGM
FADFIDEPSVELIGVEPAGKGIDTPMHGAPLKHGKTGIFFGMKAPLMQNSEGQIEESYSISAGLDFPSVGPQHAHLNATG
RARYESATDDEALEAFQQLARCEGIIPALESAHAIAYAVKMARECTKETILVVNLSGRGDKDIFTVSDILNGKEV

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=390, Percent_Identity=80.2564102564103, Blast_Score=650, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321412, Length=384, Percent_Identity=52.34375, Blast_Score=417, Evalue=1e-117,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 42796; Mature: 42664

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLKLNPYFGEYGGMYVPQILVPALKQLETAFVEAQEDDDFKAEFTDLLKNYAGRPTAL
CCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEE
TLTRNLSPNPMVKIYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVAT
EEECCCCCCCEEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHH
ALACALLGLKCKVYMGAKDVARQSPNVFRMRLMGAEVIPVTSGSATLKDACNEAMRDWSG
HHHHHHHCCEEEEEECCHHHHHCCCCCEEEEECCCEEEEECCCCHHHHHHHHHHHHHCCC
SYEKAHYLLGTAAGPHPFPTIVREFQRIIGEETKKQMLEREGRLPDAVIACVGGGSNAIG
CHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHH
MFADFIDEPSVELIGVEPAGKGIDTPMHGAPLKHGKTGIFFGMKAPLMQNSEGQIEESYS
HHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCE
ISAGLDFPSVGPQHAHLNATGRARYESATDDEALEAFQQLARCEGIIPALESAHAIAYAV
EECCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
KMARECTKETILVVNLSGRGDKDIFTVSDILNGKEV
HHHHHHCCCEEEEEEECCCCCCCEEEHHHHCCCCCC
>Mature Secondary Structure 
SKLKLNPYFGEYGGMYVPQILVPALKQLETAFVEAQEDDDFKAEFTDLLKNYAGRPTAL
CCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEE
TLTRNLSPNPMVKIYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVAT
EEECCCCCCCEEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHH
ALACALLGLKCKVYMGAKDVARQSPNVFRMRLMGAEVIPVTSGSATLKDACNEAMRDWSG
HHHHHHHCCEEEEEECCHHHHHCCCCCEEEEECCCEEEEECCCCHHHHHHHHHHHHHCCC
SYEKAHYLLGTAAGPHPFPTIVREFQRIIGEETKKQMLEREGRLPDAVIACVGGGSNAIG
CHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHH
MFADFIDEPSVELIGVEPAGKGIDTPMHGAPLKHGKTGIFFGMKAPLMQNSEGQIEESYS
HHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCE
ISAGLDFPSVGPQHAHLNATGRARYESATDDEALEAFQQLARCEGIIPALESAHAIAYAV
EECCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
KMARECTKETILVVNLSGRGDKDIFTVSDILNGKEV
HHHHHHCCCEEEEEEECCCCCCCEEEHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA