Click here to switch to the map view.

The map label for this gene is pheT [H]

Identifier: 125624962

GI number: 125624962

Start: 2159623

End: 2162016

Strand: Reverse

Name: pheT [H]

Synonym: llmg_2195

Alternate gene names: 125624962

Gene position: 2162016-2159623 (Counterclockwise)

Preceding gene: 125624963

Following gene: 125624961

Centisome position: 85.47

GC content: 37.64

Gene sequence:

>2394_bases
ATGTTAGTATCATATAAATGGTTAAAAGAGTTGGTGCCAAATCTTACGGCTACGCCAGCTGAATTAGAACAAAAGATGTC
AACGTCTGGGATTGAGGTTGAAGGAGTGACGAGTCCACAAGAAGGTTTGTCAAAACTTGTTGTCGGAGAAGTTCTTTCTA
GTGAAGATATTCCTGAAACACATTTGCATATTACACAAGTTAATGTTGGGGCTGACGAGGCATTACAAATTGTTTGTGGA
GCGCCAAATGTTCGTGTGGGGATGAAAGTAATTGTGGCACTTGTCGGTGCTCGAATTGCGGATAATTATAAAATCAAAAA
AGGTAAAATTCGTGGAGTTGAATCTCTCGGGATGCTTTGTGCACTTGATGAAATAGGATTTGATGAAAAAATTAATCCAA
TGAAGCATGAAGATGGTATTTTTGAAATGCCAGCGGATGCTAAAGTTGGTGATAGTATTTTCCCTTATCTTGATATGGAC
GATGAAATCATCGAATTATCAATCACTCCAAATCGTGCGGATGCTTTGTCAATGAATGGGGCAGCATGGGAAGTTGGAGC
AATCTATGATTTACCAGTTAAGCTTGAGGAAAAATCTTTAGTAGAAGCTTCAGAATCAGTAGCAAGCAAAATTACAGTTA
AGGTTGAAACAGATAAAGTTCCAACATATAAAATCCGTTTGATTGAAGGGGTTAAAATTGCGAAATCACCTCAATGGTTG
CAAAACCGATTGATGAATGCGGGTGTAAAACCAATTAATAATGTGGTTGATGTGACCAATTATGTATTGATGGCATTTGG
TCAACCTTTGCATAGTTTTGACTTTGCCAAATTTGGTTCTGATGAAATCTTGGTTCGTCAGGCTAAGTCTGGTGAAAAAA
TAGCCACTTTAGACCATGTTGAACGTGAATTAGATGACTCTGATATTGTAGTCACAGCAAATGGACTTCCTGTAGCGCTT
GGTGGTGTCATGGGTGGTGCAGACAGTGAGATTACTGATGAAACAACAAATGTTGCTCTTGAAGCAGCTTTGTTTGACGG
AACTTCAATTCGTAAAACTTCGCAAAAATTTGCTTTGCGCTCAGAAGCATCAAGTCGTTTTGAAAAAGGAATTAATGAAG
GAACAGTTCGTGAGGCTCTTGATTTTGCAGCAGCAATGATTGTTGAATTGGCTGGCGGGAAAGTTCTTTCAGGCCTTGTT
GAATCAAATGATTATCAACCTCTGTTACCAAAAGTTTCAATTACTTTAAGTCGTGTTAATGGGGCTTTAGGAACAGATTT
ATCACTTGAAACTGTGAAGAAAATTTTTGTTCAACTTGGTTTTGGAGTCGAAGTTGAGGGAGAAAAATTTACTTGTGAAA
TTCCATCACGTCGTTGGGATATTCATATTGAAGCTGATTTGGTTGAAGAAGTTGCTCGGATTTATGGATATGATAATTTG
CCAAGTACTTTGCCTCTTTCACAAAATGCTGGTGAGTTGACTGACATGCAAAAATTCCGTCGAACGGTAAGAACTGGACT
TGAAAGTTCAGGTCTTAATGAAGTCATTGGTTACTCACTTGTGACTCCAGAAAAAGCGACTGAATTTGTGGGTGAGCTTG
AAACAACATCGCTCATGATGCCAATGACTGAAGAACGTCAAACACTTCGTGCAAATATGATTCCAGGACTTTTGGACATT
GTTAATTACAATCAAAATCGTAAAAATGCTGACGTAGCAATTTATGAAATTGGCAATATTTTCTTACCAAATGCAGATGA
TATTCGTCCTACAGAAGTACCAAATCTTGCTTTTGCTATTTCTGGAAATGTTGTGGATAAATCATACAACGGACAAGCTG
TTCCTGTGGATTTCTACTATGCTAAGGGAATTGTGGAAAACCTTCTTGAAACTTACGAAGAAGTTGAATTTGTTCCAACT
AATAATCAAGCGGCAATGCATCCAGGACGGACTGCTGTCATTAACATCAATGGTCGCCTGGCTGGTTTTGTGGGACAAAT
TCATCCGGCTACAGCTAAAAAATATGATGTAGCAGAAACTTATGTTGCTAGTCTCGACATGAAAGTGATGCTTGAAGAAT
TGCCAGCACAAACCATCTTTAATGATATTCCAAAAGTTCAAGCAGTTCATCGTGATATTGCACTTTTGATTGATGCTGAG
GTTACACATGCCCAAATCGTTTCTGTCATTAAATCAAGTCGCGTTAAAACACTTAAGCAAGTTGAGTTATTTGATATTTA
TCAAGGTAAAAATTTACCTGCTGGTAAAAAATCAATGGCCTATAGCTTAACTTTCCAACCGGCTGAAAATACAATGACTG
ATGATGAAATTACGGCTGCTGTTAATAAAATTACAAAAAATCTTGTTGAAAAATTGAATGTAGAAATTCGTTAA

Upstream 100 bases:

>100_bases
GCATTGTCGATTTCGACATTCGAAAAGGGAGGACTCCCTTCGATGGAGCGATTTGGAAAATAAATAGTATAAAAAACTGT
GAATAGAAAGTTGAAATAAC

Downstream 100 bases:

>100_bases
AAGAAAATAAGATCACTGACAAAGCTGTCAGTAAAAAACTCTATCGGTAGTTACTGATAGAGTTTTTTCATCTTTGATGA
TTATCAAAATATAAATCATT

Product: phenylalanyl-tRNA synthetase subunit beta

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase beta chain; PheRS [H]

Number of amino acids: Translated: 797; Mature: 797

Protein sequence:

>797_residues
MLVSYKWLKELVPNLTATPAELEQKMSTSGIEVEGVTSPQEGLSKLVVGEVLSSEDIPETHLHITQVNVGADEALQIVCG
APNVRVGMKVIVALVGARIADNYKIKKGKIRGVESLGMLCALDEIGFDEKINPMKHEDGIFEMPADAKVGDSIFPYLDMD
DEIIELSITPNRADALSMNGAAWEVGAIYDLPVKLEEKSLVEASESVASKITVKVETDKVPTYKIRLIEGVKIAKSPQWL
QNRLMNAGVKPINNVVDVTNYVLMAFGQPLHSFDFAKFGSDEILVRQAKSGEKIATLDHVERELDDSDIVVTANGLPVAL
GGVMGGADSEITDETTNVALEAALFDGTSIRKTSQKFALRSEASSRFEKGINEGTVREALDFAAAMIVELAGGKVLSGLV
ESNDYQPLLPKVSITLSRVNGALGTDLSLETVKKIFVQLGFGVEVEGEKFTCEIPSRRWDIHIEADLVEEVARIYGYDNL
PSTLPLSQNAGELTDMQKFRRTVRTGLESSGLNEVIGYSLVTPEKATEFVGELETTSLMMPMTEERQTLRANMIPGLLDI
VNYNQNRKNADVAIYEIGNIFLPNADDIRPTEVPNLAFAISGNVVDKSYNGQAVPVDFYYAKGIVENLLETYEEVEFVPT
NNQAAMHPGRTAVININGRLAGFVGQIHPATAKKYDVAETYVASLDMKVMLEELPAQTIFNDIPKVQAVHRDIALLIDAE
VTHAQIVSVIKSSRVKTLKQVELFDIYQGKNLPAGKKSMAYSLTFQPAENTMTDDEITAAVNKITKNLVEKLNVEIR

Sequences:

>Translated_797_residues
MLVSYKWLKELVPNLTATPAELEQKMSTSGIEVEGVTSPQEGLSKLVVGEVLSSEDIPETHLHITQVNVGADEALQIVCG
APNVRVGMKVIVALVGARIADNYKIKKGKIRGVESLGMLCALDEIGFDEKINPMKHEDGIFEMPADAKVGDSIFPYLDMD
DEIIELSITPNRADALSMNGAAWEVGAIYDLPVKLEEKSLVEASESVASKITVKVETDKVPTYKIRLIEGVKIAKSPQWL
QNRLMNAGVKPINNVVDVTNYVLMAFGQPLHSFDFAKFGSDEILVRQAKSGEKIATLDHVERELDDSDIVVTANGLPVAL
GGVMGGADSEITDETTNVALEAALFDGTSIRKTSQKFALRSEASSRFEKGINEGTVREALDFAAAMIVELAGGKVLSGLV
ESNDYQPLLPKVSITLSRVNGALGTDLSLETVKKIFVQLGFGVEVEGEKFTCEIPSRRWDIHIEADLVEEVARIYGYDNL
PSTLPLSQNAGELTDMQKFRRTVRTGLESSGLNEVIGYSLVTPEKATEFVGELETTSLMMPMTEERQTLRANMIPGLLDI
VNYNQNRKNADVAIYEIGNIFLPNADDIRPTEVPNLAFAISGNVVDKSYNGQAVPVDFYYAKGIVENLLETYEEVEFVPT
NNQAAMHPGRTAVININGRLAGFVGQIHPATAKKYDVAETYVASLDMKVMLEELPAQTIFNDIPKVQAVHRDIALLIDAE
VTHAQIVSVIKSSRVKTLKQVELFDIYQGKNLPAGKKSMAYSLTFQPAENTMTDDEITAAVNKITKNLVEKLNVEIR
>Mature_797_residues
MLVSYKWLKELVPNLTATPAELEQKMSTSGIEVEGVTSPQEGLSKLVVGEVLSSEDIPETHLHITQVNVGADEALQIVCG
APNVRVGMKVIVALVGARIADNYKIKKGKIRGVESLGMLCALDEIGFDEKINPMKHEDGIFEMPADAKVGDSIFPYLDMD
DEIIELSITPNRADALSMNGAAWEVGAIYDLPVKLEEKSLVEASESVASKITVKVETDKVPTYKIRLIEGVKIAKSPQWL
QNRLMNAGVKPINNVVDVTNYVLMAFGQPLHSFDFAKFGSDEILVRQAKSGEKIATLDHVERELDDSDIVVTANGLPVAL
GGVMGGADSEITDETTNVALEAALFDGTSIRKTSQKFALRSEASSRFEKGINEGTVREALDFAAAMIVELAGGKVLSGLV
ESNDYQPLLPKVSITLSRVNGALGTDLSLETVKKIFVQLGFGVEVEGEKFTCEIPSRRWDIHIEADLVEEVARIYGYDNL
PSTLPLSQNAGELTDMQKFRRTVRTGLESSGLNEVIGYSLVTPEKATEFVGELETTSLMMPMTEERQTLRANMIPGLLDI
VNYNQNRKNADVAIYEIGNIFLPNADDIRPTEVPNLAFAISGNVVDKSYNGQAVPVDFYYAKGIVENLLETYEEVEFVPT
NNQAAMHPGRTAVININGRLAGFVGQIHPATAKKYDVAETYVASLDMKVMLEELPAQTIFNDIPKVQAVHRDIALLIDAE
VTHAQIVSVIKSSRVKTLKQVELFDIYQGKNLPAGKKSMAYSLTFQPAENTMTDDEITAAVNKITKNLVEKLNVEIR

Specific function: Unknown

COG id: COG0072

COG function: function code J; Phenylalanyl-tRNA synthetase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 tRNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI124028525, Length=403, Percent_Identity=23.8213399503722, Blast_Score=81, Evalue=4e-15,
Organism=Escherichia coli, GI1788006, Length=815, Percent_Identity=35.9509202453988, Blast_Score=443, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17533403, Length=375, Percent_Identity=20.5333333333333, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21355211, Length=390, Percent_Identity=22.0512820512821, Blast_Score=84, Evalue=5e-16,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005146
- InterPro:   IPR005147
- InterPro:   IPR009061
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004532
- InterPro:   IPR020825
- InterPro:   IPR005121
- InterPro:   IPR002547 [H]

Pfam domain/function: PF03483 B3_4; PF03484 B5; PF03147 FDX-ACB; PF01588 tRNA_bind [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 87183; Mature: 87183

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS50886 TRBD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVSYKWLKELVPNLTATPAELEQKMSTSGIEVEGVTSPQEGLSKLVVGEVLSSEDIPET
CCCCHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCC
HLHITQVNVGADEALQIVCGAPNVRVGMKVIVALVGARIADNYKIKKGKIRGVESLGMLC
EEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHH
ALDEIGFDEKINPMKHEDGIFEMPADAKVGDSIFPYLDMDDEIIELSITPNRADALSMNG
HHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEECCC
AAWEVGAIYDLPVKLEEKSLVEASESVASKITVKVETDKVPTYKIRLIEGVKIAKSPQWL
CEEEECEEEECCCEECHHHHHHHHHHHHCEEEEEEECCCCCEEEEEEEECCEECCCHHHH
QNRLMNAGVKPINNVVDVTNYVLMAFGQPLHSFDFAKFGSDEILVRQAKSGEKIATLDHV
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHCCHHHCCCCCEEEEECCCCCEEEHHHHH
ERELDDSDIVVTANGLPVALGGVMGGADSEITDETTNVALEAALFDGTSIRKTSQKFALR
HHHCCCCCEEEEECCCCEEECCCCCCCCCCCCCCHHHEEEEEEEECCCCHHHHHHHHHHH
SEASSRFEKGINEGTVREALDFAAAMIVELAGGKVLSGLVESNDYQPLLPKVSITLSRVN
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHEEEEEECC
GALGTDLSLETVKKIFVQLGFGVEVEGEKFTCEIPSRRWDIHIEADLVEEVARIYGYDNL
CCCCCCCCHHHHHHHHHHHCCCEEECCCEEEEECCCCEEEEEEEHHHHHHHHHHCCCCCC
PSTLPLSQNAGELTDMQKFRRTVRTGLESSGLNEVIGYSLVTPEKATEFVGELETTSLMM
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHCCEEECCHHHHHHHHCCCHHEEEC
PMTEERQTLRANMIPGLLDIVNYNQNRKNADVAIYEIGNIFLPNADDIRPTEVPNLAFAI
CCHHHHHHHHHHHCHHHHHHHCCCCCCCCCCEEEEEECCEECCCCCCCCCCCCCCEEEEE
SGNVVDKSYNGQAVPVDFYYAKGIVENLLETYEEVEFVPTNNQAAMHPGRTAVININGRL
ECCEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHCEEEECCCCCEECCCCEEEEEECCEE
AGFVGQIHPATAKKYDVAETYVASLDMKVMLEELPAQTIFNDIPKVQAVHRDIALLIDAE
EEHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHCCEEEEEECC
VTHAQIVSVIKSSRVKTLKQVELFDIYQGKNLPAGKKSMAYSLTFQPAENTMTDDEITAA
CHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHH
VNKITKNLVEKLNVEIR
HHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLVSYKWLKELVPNLTATPAELEQKMSTSGIEVEGVTSPQEGLSKLVVGEVLSSEDIPET
CCCCHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCC
HLHITQVNVGADEALQIVCGAPNVRVGMKVIVALVGARIADNYKIKKGKIRGVESLGMLC
EEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHH
ALDEIGFDEKINPMKHEDGIFEMPADAKVGDSIFPYLDMDDEIIELSITPNRADALSMNG
HHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEECCC
AAWEVGAIYDLPVKLEEKSLVEASESVASKITVKVETDKVPTYKIRLIEGVKIAKSPQWL
CEEEECEEEECCCEECHHHHHHHHHHHHCEEEEEEECCCCCEEEEEEEECCEECCCHHHH
QNRLMNAGVKPINNVVDVTNYVLMAFGQPLHSFDFAKFGSDEILVRQAKSGEKIATLDHV
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHCCHHHCCCCCEEEEECCCCCEEEHHHHH
ERELDDSDIVVTANGLPVALGGVMGGADSEITDETTNVALEAALFDGTSIRKTSQKFALR
HHHCCCCCEEEEECCCCEEECCCCCCCCCCCCCCHHHEEEEEEEECCCCHHHHHHHHHHH
SEASSRFEKGINEGTVREALDFAAAMIVELAGGKVLSGLVESNDYQPLLPKVSITLSRVN
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHEEEEEECC
GALGTDLSLETVKKIFVQLGFGVEVEGEKFTCEIPSRRWDIHIEADLVEEVARIYGYDNL
CCCCCCCCHHHHHHHHHHHCCCEEECCCEEEEECCCCEEEEEEEHHHHHHHHHHCCCCCC
PSTLPLSQNAGELTDMQKFRRTVRTGLESSGLNEVIGYSLVTPEKATEFVGELETTSLMM
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHCCEEECCHHHHHHHHCCCHHEEEC
PMTEERQTLRANMIPGLLDIVNYNQNRKNADVAIYEIGNIFLPNADDIRPTEVPNLAFAI
CCHHHHHHHHHHHCHHHHHHHCCCCCCCCCCEEEEEECCEECCCCCCCCCCCCCCEEEEE
SGNVVDKSYNGQAVPVDFYYAKGIVENLLETYEEVEFVPTNNQAAMHPGRTAVININGRL
ECCEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHCEEEECCCCCEECCCCEEEEEECCEE
AGFVGQIHPATAKKYDVAETYVASLDMKVMLEELPAQTIFNDIPKVQAVHRDIALLIDAE
EEHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHCCEEEEEECC
VTHAQIVSVIKSSRVKTLKQVELFDIYQGKNLPAGKKSMAYSLTFQPAENTMTDDEITAA
CHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHH
VNKITKNLVEKLNVEIR
HHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]