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The map label for this gene is pnuC1 [H]

Identifier: 125624512

GI number: 125624512

Start: 1694953

End: 1695666

Strand: Reverse

Name: pnuC1 [H]

Synonym: llmg_1719

Alternate gene names: 125624512

Gene position: 1695666-1694953 (Counterclockwise)

Preceding gene: 125624513

Following gene: 125624511

Centisome position: 67.04

GC content: 34.59

Gene sequence:

>714_bases
ATGACAAAAGAATCATGGCTTTTTAAACAACTTTTTGCAAATTGGAAAAAGTTTGAAATCACATATATTGCTATTTTATT
GTTATTACAAATCATTGTTTATATTATTGCTCCGGATTCCTTCATTGGGATGATTTCGGGTGTCTTTGGAGTGCTTTGTC
TCATTTATGGGATGAAAGGGCGTAAAATTAATTTTGCGTTTGGATTGATACAGACTATAGCGATGACTTTAATAGCTTAT
CAGACCCATTCATGGATGAGTTTTGTAATGGGAATTTTTTATATTTTATCTCAACCTGTTGGTTGGTTTTTTTGGGGACA
AGATGATGCTATTCATGAATTTAAACCAAAAACTCGTCGACTGATATTTTTAGGAGCTTTTATTGCTTGGCTAATTGTTT
GGGTTATTGATGCTTTTTTAAATGGCCAACTTCCTTATTTTGACTCCTTAAATCTGATTATCCCACTTATCGCGCAAATA
TTATACATTTTGAAATATAAAGAAAATTGGTCACTCTGGATTGTGGTTAATACTGCCGCCGTGGTCTATTGGTCAATATT
GACAATACAATTTATAATGGACGTAAATACTCAAGGTCAATTGGGAATGTATTTATCACAAGTTGCTCTGCAAGGAGCCT
TACTCTTCAATGCCATCTATGCAAATCGGGTTTGGGCAAGCGGCGAAGCGGATAATGAAGGTGGTACGAAATGA

Upstream 100 bases:

>100_bases
ATGATTTAGTTTCAGGGGATGATAAGGTCATTGAAGGTGAAAAACGAACAATTGAAATTGCTTTAGAAGTTTTAAATAAG
TAATTTGAAAAGGAGAAGAA

Downstream 100 bases:

>100_bases
TTAGTCAAAATACCCTAAGGATTTAGGGTGTTTTTTGTTCTTATTAACATCCAAAAGGAGAGCAGCTCCTACATTTTTTT
GCTATAATAAACATTATGAA

Product: PnuC1 protein

Products: nicotinamide nucleotide [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MTKESWLFKQLFANWKKFEITYIAILLLLQIIVYIIAPDSFIGMISGVFGVLCLIYGMKGRKINFAFGLIQTIAMTLIAY
QTHSWMSFVMGIFYILSQPVGWFFWGQDDAIHEFKPKTRRLIFLGAFIAWLIVWVIDAFLNGQLPYFDSLNLIIPLIAQI
LYILKYKENWSLWIVVNTAAVVYWSILTIQFIMDVNTQGQLGMYLSQVALQGALLFNAIYANRVWASGEADNEGGTK

Sequences:

>Translated_237_residues
MTKESWLFKQLFANWKKFEITYIAILLLLQIIVYIIAPDSFIGMISGVFGVLCLIYGMKGRKINFAFGLIQTIAMTLIAY
QTHSWMSFVMGIFYILSQPVGWFFWGQDDAIHEFKPKTRRLIFLGAFIAWLIVWVIDAFLNGQLPYFDSLNLIIPLIAQI
LYILKYKENWSLWIVVNTAAVVYWSILTIQFIMDVNTQGQLGMYLSQVALQGALLFNAIYANRVWASGEADNEGGTK
>Mature_236_residues
TKESWLFKQLFANWKKFEITYIAILLLLQIIVYIIAPDSFIGMISGVFGVLCLIYGMKGRKINFAFGLIQTIAMTLIAYQ
THSWMSFVMGIFYILSQPVGWFFWGQDDAIHEFKPKTRRLIFLGAFIAWLIVWVIDAFLNGQLPYFDSLNLIIPLIAQIL
YILKYKENWSLWIVVNTAAVVYWSILTIQFIMDVNTQGQLGMYLSQVALQGALLFNAIYANRVWASGEADNEGGTK

Specific function: Required for nicotinamide riboside transport across the inner membrane [H]

COG id: COG3201

COG function: function code H; Nicotinamide mononucleotide transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006419 [H]

Pfam domain/function: PF04973 NMN_transporter [H]

EC number: NA

Molecular weight: Translated: 27199; Mature: 27067

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKESWLFKQLFANWKKFEITYIAILLLLQIIVYIIAPDSFIGMISGVFGVLCLIYGMKG
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
RKINFAFGLIQTIAMTLIAYQTHSWMSFVMGIFYILSQPVGWFFWGQDDAIHEFKPKTRR
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHCCCHHHH
LIFLGAFIAWLIVWVIDAFLNGQLPYFDSLNLIIPLIAQILYILKYKENWSLWIVVNTAA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHH
VVYWSILTIQFIMDVNTQGQLGMYLSQVALQGALLFNAIYANRVWASGEADNEGGTK
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCCCCC
>Mature Secondary Structure 
TKESWLFKQLFANWKKFEITYIAILLLLQIIVYIIAPDSFIGMISGVFGVLCLIYGMKG
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
RKINFAFGLIQTIAMTLIAYQTHSWMSFVMGIFYILSQPVGWFFWGQDDAIHEFKPKTRR
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHCCCHHHH
LIFLGAFIAWLIVWVIDAFLNGQLPYFDSLNLIIPLIAQILYILKYKENWSLWIVVNTAA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHH
VVYWSILTIQFIMDVNTQGQLGMYLSQVALQGALLFNAIYANRVWASGEADNEGGTK
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nicotinamide nucleotide [Periplasm] [C]

Specific reaction: nicotinamide nucleotide [Periplasm] = nicotinamide nucleotide [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12446641; 7542800 [H]