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The map label for this gene is udp [H]

Identifier: 125624513

GI number: 125624513

Start: 1695684

End: 1696400

Strand: Reverse

Name: udp [H]

Synonym: llmg_1720

Alternate gene names: 125624513

Gene position: 1696400-1695684 (Counterclockwise)

Preceding gene: 125624514

Following gene: 125624512

Centisome position: 67.07

GC content: 37.94

Gene sequence:

>717_bases
ATGGAAGAGTTACAAGCACACATCCAATTGAAGAAAACTGATGCAGTAGAAGATGCAATTATTGTAGGTGATCCAGCACG
GGTAGACCAAGTGGCAAAATTTTTGACGGAATTCAGAGAATTAAAATATAACCGTGAATTTCGTTCACTTCGTGGCACCT
ATAAAAACAAAGAAGTCTTAGTTCTGTCAACAGGAGTTGGGGCGCCGTCAGCTGCTATTGCCATTGAAGAACTTCATAAT
ATTGGAGTTAAGAGAATTATCAGAGTAGGCTCTGCTGGAGCTTTGCAGTTAGGGATTGGTTTAGGAAATCCAATTATTGG
AGAAGGAGCAGTGCGTGACGATGGTCTGACAAAGATGTATGTTCCAGAACAATATCCGGCAGTTCCCTCTAGTACTTTAC
TAGCAAAAGCAAAAGAAATTGCACCTGAGGCCATTTATGGAATTATTCGTTCGCATGACGGTTTTTATATGGATAATAAT
GAACAGACACAGGAATATTGGTCAAATTTTGGACTTATTGGTGAGGATATGGAGTCTGGAGCCTTATTTACTGTTGGACG
TCTGCGAGGAATAGAAACTTTATCTATTTTAAATAATGTTGTAGCTTATAAAGAAGATTTACAAGCCGGGGTAAATGATT
TAGTTTCAGGGGATGATAAGGTCATTGAAGGTGAAAAACGAACAATTGAAATTGCTTTAGAAGTTTTAAATAAGTAA

Upstream 100 bases:

>100_bases
CAATTTAATAATTAAGTTCTTTTAATTGTTTAAAATATTTGCTATAATTTAATTGTTTCAAACAAATCAAATAAACCTTT
ATGAAATGAAGGAGTGACTA

Downstream 100 bases:

>100_bases
TTTGAAAAGGAGAAGAAATGACAAAAGAATCATGGCTTTTTAAACAACTTTTTGCAAATTGGAAAAAGTTTGAAATCACA
TATATTGCTATTTTATTGTT

Product: uridine phosphorylase

Products: NA

Alternate protein names: UPase; UrdPase [H]

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MEELQAHIQLKKTDAVEDAIIVGDPARVDQVAKFLTEFRELKYNREFRSLRGTYKNKEVLVLSTGVGAPSAAIAIEELHN
IGVKRIIRVGSAGALQLGIGLGNPIIGEGAVRDDGLTKMYVPEQYPAVPSSTLLAKAKEIAPEAIYGIIRSHDGFYMDNN
EQTQEYWSNFGLIGEDMESGALFTVGRLRGIETLSILNNVVAYKEDLQAGVNDLVSGDDKVIEGEKRTIEIALEVLNK

Sequences:

>Translated_238_residues
MEELQAHIQLKKTDAVEDAIIVGDPARVDQVAKFLTEFRELKYNREFRSLRGTYKNKEVLVLSTGVGAPSAAIAIEELHN
IGVKRIIRVGSAGALQLGIGLGNPIIGEGAVRDDGLTKMYVPEQYPAVPSSTLLAKAKEIAPEAIYGIIRSHDGFYMDNN
EQTQEYWSNFGLIGEDMESGALFTVGRLRGIETLSILNNVVAYKEDLQAGVNDLVSGDDKVIEGEKRTIEIALEVLNK
>Mature_238_residues
MEELQAHIQLKKTDAVEDAIIVGDPARVDQVAKFLTEFRELKYNREFRSLRGTYKNKEVLVLSTGVGAPSAAIAIEELHN
IGVKRIIRVGSAGALQLGIGLGNPIIGEGAVRDDGLTKMYVPEQYPAVPSSTLLAKAKEIAPEAIYGIIRSHDGFYMDNN
EQTQEYWSNFGLIGEDMESGALFTVGRLRGIETLSILNNVVAYKEDLQAGVNDLVSGDDKVIEGEKRTIEIALEVLNK

Specific function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synth

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790265, Length=204, Percent_Identity=31.8627450980392, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790844, Length=240, Percent_Identity=28.75, Blast_Score=88, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- InterPro:   IPR010058 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.3 [H]

Molecular weight: Translated: 26060; Mature: 26060

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEELQAHIQLKKTDAVEDAIIVGDPARVDQVAKFLTEFRELKYNREFRSLRGTYKNKEVL
CCCHHHHEEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCEEE
VLSTGVGAPSAAIAIEELHNIGVKRIIRVGSAGALQLGIGLGNPIIGEGAVRDDGLTKMY
EEECCCCCCHHHHHHHHHHHCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEE
VPEQYPAVPSSTLLAKAKEIAPEAIYGIIRSHDGFYMDNNEQTQEYWSNFGLIGEDMESG
CCCCCCCCCCHHHHHHHHHHCHHHHHHHHHCCCCEEECCCCHHHHHHHHCCCCCCCCCCC
ALFTVGRLRGIETLSILNNVVAYKEDLQAGVNDLVSGDDKVIEGEKRTIEIALEVLNK
CEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHCC
>Mature Secondary Structure
MEELQAHIQLKKTDAVEDAIIVGDPARVDQVAKFLTEFRELKYNREFRSLRGTYKNKEVL
CCCHHHHEEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCEEE
VLSTGVGAPSAAIAIEELHNIGVKRIIRVGSAGALQLGIGLGNPIIGEGAVRDDGLTKMY
EEECCCCCCHHHHHHHHHHHCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEE
VPEQYPAVPSSTLLAKAKEIAPEAIYGIIRSHDGFYMDNNEQTQEYWSNFGLIGEDMESG
CCCCCCCCCCHHHHHHHHHHCHHHHHHHHHCCCCEEECCCCHHHHHHHHCCCCCCCCCCC
ALFTVGRLRGIETLSILNNVVAYKEDLQAGVNDLVSGDDKVIEGEKRTIEIALEVLNK
CEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]