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The map label for this gene is 125623294

Identifier: 125623294

GI number: 125623294

Start: 417811

End: 418800

Strand: Direct

Name: 125623294

Synonym: llmg_0427

Alternate gene names: NA

Gene position: 417811-418800 (Clockwise)

Preceding gene: 125623293

Following gene: 125623295

Centisome position: 16.52

GC content: 35.35

Gene sequence:

>990_bases
ATGAGTATCTCTGAGAAGAAAATTAAGACAAAGATACCGGGGAAACTTTTTTTTGCAGGTGAATATGCGGTCACAAAAGA
AGGAAATCTTGCCCTCATTACGACAATTGAAACAAATTTTGAAATGAGTATTTCAAGAGCGAGTGACAAATCGGTTCTCA
AAACAAATGTTGGACTTGCTGATTTTGAATTTTCATTGACCAAAATTGAATTTGATAAAGAAAGTCCTTGGAATTTTGCG
CTGACAGCCTTAAAAAATACTTTGTCAGCTGCTGACAGTTCTAAAAAAGAGTCTGTCAGTAAAATTTCTGAGCTGTCAGT
AGAAATATGCCTTGAAATTCGGAGTGATTTAGGCTTTGGTGAAAATAAAAAAGGCTATGGCTCAAGTGCATCAGTTGTTT
GTGGCGTAGTCAATGCGGTTAACCAATTTTTTGATTTACAACTTTCCCTTGAAAAACGGTTTGAAATTGCAGCAAAGACC
CATTTTGAAGTGCAAGGTTCCGGTTCAATGGGGGATATTGCGGCTATTATGTATGGTGGCTCAGTTTTCTATCAGAATCA
TAACCGTATCCTTCCTCTTGAGATTCCTTGGAAAACCTATGTTGTTCAAACAGGAAAAGCAGCCAAAACTGCTGAAAAAA
TCAAAATCAAACTCTCTGATGAATTTTATCAAACTTCAAATGAGTTAGTTATCGAAATGGCAACAGCGATTGACATTCAA
GATTTTAGCTTATTCAAAGAAAAATTATCAGAAAATCAACTTTTACTTTTGGAAAATATTCCAGAAGGCTATATGACTAA
AGAACTAGCTCTTGCATTAAACTTGCTCAATAGCTATCCAGAGCTTGCCGCTAAAATCTCTGGTGCTGGATTTGGGGAGA
ACCTTATTTTGTTTGCTCAAAATTCAATGGCTATTGCTGAGGTTCAAAAAAAATTATCCGAATATGGAATCAATCTTGAA
GAGTTTAAGATTGCTCAAAAAAATAACTGA

Upstream 100 bases:

>100_bases
AAAATTATTACTGACCATGCGACAGAAAAAATCTTGTTAACCAAGTTAAAAGCAGAGTTTCCAGAATTAACTTTTGATAT
TGCACGTGCTGGAGGCGCTT

Downstream 100 bases:

>100_bases
GTTTAACCTGCTAAAAACTAAAAAAGAAAACAAAGATAGATTTAAGCCTGTACGAGCCTGATTTTTCTTACTTTTCCTGT
TTTTAAAAGACTAGGTTTTA

Product: phosphomevalonate kinase

Products: ADP; (R)-5-diphosphomevalonate

Alternate protein names: Mevalonate Kinase

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MSISEKKIKTKIPGKLFFAGEYAVTKEGNLALITTIETNFEMSISRASDKSVLKTNVGLADFEFSLTKIEFDKESPWNFA
LTALKNTLSAADSSKKESVSKISELSVEICLEIRSDLGFGENKKGYGSSASVVCGVVNAVNQFFDLQLSLEKRFEIAAKT
HFEVQGSGSMGDIAAIMYGGSVFYQNHNRILPLEIPWKTYVVQTGKAAKTAEKIKIKLSDEFYQTSNELVIEMATAIDIQ
DFSLFKEKLSENQLLLLENIPEGYMTKELALALNLLNSYPELAAKISGAGFGENLILFAQNSMAIAEVQKKLSEYGINLE
EFKIAQKNN

Sequences:

>Translated_329_residues
MSISEKKIKTKIPGKLFFAGEYAVTKEGNLALITTIETNFEMSISRASDKSVLKTNVGLADFEFSLTKIEFDKESPWNFA
LTALKNTLSAADSSKKESVSKISELSVEICLEIRSDLGFGENKKGYGSSASVVCGVVNAVNQFFDLQLSLEKRFEIAAKT
HFEVQGSGSMGDIAAIMYGGSVFYQNHNRILPLEIPWKTYVVQTGKAAKTAEKIKIKLSDEFYQTSNELVIEMATAIDIQ
DFSLFKEKLSENQLLLLENIPEGYMTKELALALNLLNSYPELAAKISGAGFGENLILFAQNSMAIAEVQKKLSEYGINLE
EFKIAQKNN
>Mature_328_residues
SISEKKIKTKIPGKLFFAGEYAVTKEGNLALITTIETNFEMSISRASDKSVLKTNVGLADFEFSLTKIEFDKESPWNFAL
TALKNTLSAADSSKKESVSKISELSVEICLEIRSDLGFGENKKGYGSSASVVCGVVNAVNQFFDLQLSLEKRFEIAAKTH
FEVQGSGSMGDIAAIMYGGSVFYQNHNRILPLEIPWKTYVVQTGKAAKTAEKIKIKLSDEFYQTSNELVIEMATAIDIQD
FSLFKEKLSENQLLLLENIPEGYMTKELALALNLLNSYPELAAKISGAGFGENLILFAQNSMAIAEVQKKLSEYGINLEE
FKIAQKNN

Specific function: Unknown

COG id: COG1577

COG function: function code I; Mevalonate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.4.2

Molecular weight: Translated: 36346; Mature: 36215

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISEKKIKTKIPGKLFFAGEYAVTKEGNLALITTIETNFEMSISRASDKSVLKTNVGLA
CCCCHHHHHHCCCCEEEEECCEEEECCCCEEEEEEEECCCEEEEECCCCCHHHHHCCCEE
DFEFSLTKIEFDKESPWNFALTALKNTLSAADSSKKESVSKISELSVEICLEIRSDLGFG
EEEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
ENKKGYGSSASVVCGVVNAVNQFFDLQLSLEKRFEIAAKTHFEVQGSGSMGDIAAIMYGG
CCCCCCCCCHHHHHHHHHHHHHHHEEEEEHHHHEEEEEEEEEEEECCCCCCCEEEEEECC
SVFYQNHNRILPLEIPWKTYVVQTGKAAKTAEKIKIKLSDEFYQTSNELVIEMATAIDIQ
EEEEECCCEEEEEEECCEEEEEECCCCCCCCEEEEEEECHHHHHCCCCEEEEEEHHCCCH
DFSLFKEKLSENQLLLLENIPEGYMTKELALALNLLNSYPELAAKISGAGFGENLILFAQ
HHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEEEC
NSMAIAEVQKKLSEYGINLEEFKIAQKNN
CCHHHHHHHHHHHHHCCCHHHEEEECCCC
>Mature Secondary Structure 
SISEKKIKTKIPGKLFFAGEYAVTKEGNLALITTIETNFEMSISRASDKSVLKTNVGLA
CCCHHHHHHCCCCEEEEECCEEEECCCCEEEEEEEECCCEEEEECCCCCHHHHHCCCEE
DFEFSLTKIEFDKESPWNFALTALKNTLSAADSSKKESVSKISELSVEICLEIRSDLGFG
EEEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
ENKKGYGSSASVVCGVVNAVNQFFDLQLSLEKRFEIAAKTHFEVQGSGSMGDIAAIMYGG
CCCCCCCCCHHHHHHHHHHHHHHHEEEEEHHHHEEEEEEEEEEEECCCCCCCEEEEEECC
SVFYQNHNRILPLEIPWKTYVVQTGKAAKTAEKIKIKLSDEFYQTSNELVIEMATAIDIQ
EEEEECCCEEEEEEECCEEEEEECCCCCCCCEEEEEEECHHHHHCCCCEEEEEEHHCCCH
DFSLFKEKLSENQLLLLENIPEGYMTKELALALNLLNSYPELAAKISGAGFGENLILFAQ
HHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEEEC
NSMAIAEVQKKLSEYGINLEEFKIAQKNN
CCHHHHHHHHHHHHHCCCHHHEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; (R)-5-phosphomevalonate

Specific reaction: ATP + (R)-5-phosphomevalonate = ADP + (R)-5-diphosphomevalonate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA