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The map label for this gene is pepA

Identifier: 125623271

GI number: 125623271

Start: 399112

End: 400179

Strand: Reverse

Name: pepA

Synonym: llmg_0403

Alternate gene names: 125623271

Gene position: 400179-399112 (Counterclockwise)

Preceding gene: 125623279

Following gene: 125623269

Centisome position: 15.82

GC content: 41.76

Gene sequence:

>1068_bases
ATGGAACTATTTGACAAAGTAAAAGCACTGACAGAAATTCAAGCCACTTCTGGTTTTGAAGGTCCCGTTCGCGACTATTT
AAAAGCTCGTATGGTTGAGCTAGGCTATCAACCAGAATTTGACGGACTTGGTGGTATTTTTGTGACAAAAGCTTCAAAAG
TCGAAAATGCCCCACGAATCATGGTTGCGGCTCACATGGATGAGGTCGGATTTATGGTCAGCTCAATCAAAGCTGACGGA
ACATTCCGCGTTGTTCCTCTTGGTGGTTGGAACCCCTTAGTCGTTTCTGGTCAACGTTTTACCCTATTTACACGTACAGG
TAAAAAGATTCCGGTTGTAACTGGTGGTCTTCCTCCACACCTTCTTCGCGGAACTGGTGTAACACCTCAAATCCCAGCAA
TCTCTGATATCATCTTTGATGGTGCATTTGAAAATGCTGCCGAAGCTGCCGAATTTGGAATCGCCCAAGGTGATTTAATT
ATTCCAGAAACAGAAACAATTCTGTCAGCAAATGGGAAAAATATCATTTCTAAAGCTTGGGATAATCGCTATGGTTGCTT
AATGATTCTTGAACTTCTTGAATTTTTAGCTGACAAAGAATTACCTGTAACATTAATTATTGGAGCGAATGTTCAAGAGG
AAGTCGGACTTCGTGGTGCAAAAGTTTCCACAACCAAATTCAATCCTGATTTATTCTTTGCCGTTGACTGTTCACCAGCA
AGCGATACCTTCGGTGACGATAATGGTCGCCTCGGAGAAGGAACAACGCTCCGTTTCTTCGACCCAGGTCATATCATGCT
TCCTGGAATGAAGAACTTCTTACTTGACACTGCAAATCATGCCAAAGTTAAAACACAAGTTTACATGGCCAAAGGGGGAA
CCGATGCAGGTGCCGCTCATTTAGCAAATGGAGGAGTTCCTTCAACAACAATCGGTGTGGTAGCCCGCTATATCCATAGC
CATCAAACTATTTTCAACATTGATGATTTTCTTCAAGCTCAAACTTTCTTGAGAGCGATTATTACTTCACTTAATACTGA
AAAAGTAGCAGAAATCAAAAACTACTAA

Upstream 100 bases:

>100_bases
GGAAATTTTAACATATTTCTTGGTATAATTATAGTGTAAATCATCAAAAGAATTACTGACAGATTTGTCAGTAAATTTTT
CAGTATCCCGGAGGAGAAAA

Downstream 100 bases:

>100_bases
TTCTAATAAAAAAACACTAGGAATTTATCCTAGTGTTTTTTTAGTTACTTTTTGATGAGGAAGTCTGACTAAAATTGAAA
GAAGGTAAAATTTTCTTCCA

Product: glutamyl-aminopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MELFDKVKALTEIQATSGFEGPVRDYLKARMVELGYQPEFDGLGGIFVTKASKVENAPRIMVAAHMDEVGFMVSSIKADG
TFRVVPLGGWNPLVVSGQRFTLFTRTGKKIPVVTGGLPPHLLRGTGVTPQIPAISDIIFDGAFENAAEAAEFGIAQGDLI
IPETETILSANGKNIISKAWDNRYGCLMILELLEFLADKELPVTLIIGANVQEEVGLRGAKVSTTKFNPDLFFAVDCSPA
SDTFGDDNGRLGEGTTLRFFDPGHIMLPGMKNFLLDTANHAKVKTQVYMAKGGTDAGAAHLANGGVPSTTIGVVARYIHS
HQTIFNIDDFLQAQTFLRAIITSLNTEKVAEIKNY

Sequences:

>Translated_355_residues
MELFDKVKALTEIQATSGFEGPVRDYLKARMVELGYQPEFDGLGGIFVTKASKVENAPRIMVAAHMDEVGFMVSSIKADG
TFRVVPLGGWNPLVVSGQRFTLFTRTGKKIPVVTGGLPPHLLRGTGVTPQIPAISDIIFDGAFENAAEAAEFGIAQGDLI
IPETETILSANGKNIISKAWDNRYGCLMILELLEFLADKELPVTLIIGANVQEEVGLRGAKVSTTKFNPDLFFAVDCSPA
SDTFGDDNGRLGEGTTLRFFDPGHIMLPGMKNFLLDTANHAKVKTQVYMAKGGTDAGAAHLANGGVPSTTIGVVARYIHS
HQTIFNIDDFLQAQTFLRAIITSLNTEKVAEIKNY
>Mature_355_residues
MELFDKVKALTEIQATSGFEGPVRDYLKARMVELGYQPEFDGLGGIFVTKASKVENAPRIMVAAHMDEVGFMVSSIKADG
TFRVVPLGGWNPLVVSGQRFTLFTRTGKKIPVVTGGLPPHLLRGTGVTPQIPAISDIIFDGAFENAAEAAEFGIAQGDLI
IPETETILSANGKNIISKAWDNRYGCLMILELLEFLADKELPVTLIIGANVQEEVGLRGAKVSTTKFNPDLFFAVDCSPA
SDTFGDDNGRLGEGTTLRFFDPGHIMLPGMKNFLLDTANHAKVKTQVYMAKGGTDAGAAHLANGGVPSTTIGVVARYIHS
HQTIFNIDDFLQAQTFLRAIITSLNTEKVAEIKNY

Specific function: Unknown

COG id: COG1363

COG function: function code G; Cellulase M and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M42 family

Homologues:

Organism=Escherichia coli, GI1790332, Length=349, Percent_Identity=34.6704871060172, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI1788727, Length=353, Percent_Identity=32.2946175637394, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI87082417, Length=345, Percent_Identity=28.1159420289855, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PEPA_LACLM (Q48677)

Other databases:

- EMBL:   X81089
- EMBL:   AM406671
- RefSeq:   YP_001031754.1
- ProteinModelPortal:   Q48677
- SMR:   Q48677
- STRING:   Q48677
- MEROPS:   M42.001
- GeneID:   4796852
- GenomeReviews:   AM406671_GR
- KEGG:   llm:llmg_0403
- eggNOG:   COG1363
- HOGENOM:   HBG426188
- OMA:   CSRYIHT
- ProtClustDB:   CLSK876740
- InterPro:   IPR017538
- InterPro:   IPR008007
- PIRSF:   PIRSF001123
- TIGRFAMs:   TIGR03107

Pfam domain/function: PF05343 Peptidase_M42

EC number: =3.4.11.7

Molecular weight: Translated: 38324; Mature: 38324

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: ACT_SITE 213-213

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELFDKVKALTEIQATSGFEGPVRDYLKARMVELGYQPEFDGLGGIFVTKASKVENAPRI
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHCCCCCEE
MVAAHMDEVGFMVSSIKADGTFRVVPLGGWNPLVVSGQRFTLFTRTGKKIPVVTGGLPPH
EEEECHHHHHHHHHHCCCCCEEEEEEECCCCCEEEECCEEEEEEECCCCCCEEECCCCHH
LLRGTGVTPQIPAISDIIFDGAFENAAEAAEFGIAQGDLIIPETETILSANGKNIISKAW
HHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCEECCCCHHEEECCCCHHHHHHH
DNRYGCLMILELLEFLADKELPVTLIIGANVQEEVGLRGAKVSTTKFNPDLFFAVDCSPA
CCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHCCCCCEEEEEEECCCEEEEEECCCC
SDTFGDDNGRLGEGTTLRFFDPGHIMLPGMKNFLLDTANHAKVKTQVYMAKGGTDAGAAH
CCCCCCCCCCCCCCCEEEEECCCCEECCCCHHHHHCCCCCCEEEEEEEEECCCCCCCHHH
LANGGVPSTTIGVVARYIHSHQTIFNIDDFLQAQTFLRAIITSLNTEKVAEIKNY
HCCCCCCHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHCCHHHHHHHCCC
>Mature Secondary Structure
MELFDKVKALTEIQATSGFEGPVRDYLKARMVELGYQPEFDGLGGIFVTKASKVENAPRI
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHCCCCCEE
MVAAHMDEVGFMVSSIKADGTFRVVPLGGWNPLVVSGQRFTLFTRTGKKIPVVTGGLPPH
EEEECHHHHHHHHHHCCCCCEEEEEEECCCCCEEEECCEEEEEEECCCCCCEEECCCCHH
LLRGTGVTPQIPAISDIIFDGAFENAAEAAEFGIAQGDLIIPETETILSANGKNIISKAW
HHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCEECCCCHHEEECCCCHHHHHHH
DNRYGCLMILELLEFLADKELPVTLIIGANVQEEVGLRGAKVSTTKFNPDLFFAVDCSPA
CCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHCCCCCEEEEEEECCCEEEEEECCCC
SDTFGDDNGRLGEGTTLRFFDPGHIMLPGMKNFLLDTANHAKVKTQVYMAKGGTDAGAAH
CCCCCCCCCCCCCCCEEEEECCCCEECCCCHHHHHCCCCCCEEEEEEEEECCCCCCCHHH
LANGGVPSTTIGVVARYIHSHQTIFNIDDFLQAQTFLRAIITSLNTEKVAEIKNY
HCCCCCCHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8535515