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The map label for this gene is 124486158

Identifier: 124486158

GI number: 124486158

Start: 1365158

End: 1365859

Strand: Reverse

Name: 124486158

Synonym: Mlab_1340

Alternate gene names: NA

Gene position: 1365859-1365158 (Counterclockwise)

Preceding gene: 124486159

Following gene: 124486157

Centisome position: 75.67

GC content: 54.42

Gene sequence:

>702_bases
ATGATTTCCCTTGATGATGCAGTAACCGCCCGTCTGGAGACACACGGGCTGAAATTTGAACTGTTGGTTGATCCCGAACT
TGCCGACAAAATGAGGCACGGCGAGGATCTCGACATCGAAGATGTTGTTGCAGCAATGTATGTATACGAGAACGCTTCGC
GCGGAGACAAGTCCCCGGACGAAGATCTGATCAAAGCGTTCAAGACCACCGATTTTACTGAGATCGCAAAACATATCATT
CTCAAAGGCGAAATCCATCTGACGACCGAGCAGCGCCGTCACCTGATTGAAGAAAAACGCAGACGCGTCATCACCTTCAT
CGCACGAAACGCCGTGAACCCGCAGACCGGTCTGCCGCATCCCGTCATGCGTATCGAGATGGCGCTGGATCAGGTCCGCA
TAAACTACGATCCCTTCAAGTCCGTGGACGATCTGGTCAAGGAGGCCGTAAAAGCGCTCCGCCCGATCCTTCCGATCCGG
TTCGAGGAACGGCGTATCGCCGCCAAATTCCCGATGGACTTTGCAGCCAGAGCGTATGCGGCCATCTCGGGCGCGGCGTA
TGTCACTATGGATAAAAACGAGTGGCAGAACGACGGGTCCTGGATCTGCGTCGTGACGATCCCTGCCGGCATGCAGGAAG
AGTTCTTCAATCTGGCGAACGCTGCGGCGAAAGGCGATGCTCAGCTCAAGATACTTGAGTAA

Upstream 100 bases:

>100_bases
TATCGACCATCGCATTTAGAAAACTGAATGTGGATGAAGTAAAGGCAGCTGTTGCCAAATTTTCCAAGACGACTCCTGCG
AAAAAGGAGTGAGTTAATCT

Downstream 100 bases:

>100_bases
CGCATACTATTAAAACAACTAAGAACGAATATTACTAGATATTTCTGGAGGAATAAAAAATGGCATCCAAGAGTAAACAT
GTTGCAAAAGGACGCGTCAC

Product: putative RNA-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MISLDDAVTARLETHGLKFELLVDPELADKMRHGEDLDIEDVVAAMYVYENASRGDKSPDEDLIKAFKTTDFTEIAKHII
LKGEIHLTTEQRRHLIEEKRRRVITFIARNAVNPQTGLPHPVMRIEMALDQVRINYDPFKSVDDLVKEAVKALRPILPIR
FEERRIAAKFPMDFAARAYAAISGAAYVTMDKNEWQNDGSWICVVTIPAGMQEEFFNLANAAAKGDAQLKILE

Sequences:

>Translated_233_residues
MISLDDAVTARLETHGLKFELLVDPELADKMRHGEDLDIEDVVAAMYVYENASRGDKSPDEDLIKAFKTTDFTEIAKHII
LKGEIHLTTEQRRHLIEEKRRRVITFIARNAVNPQTGLPHPVMRIEMALDQVRINYDPFKSVDDLVKEAVKALRPILPIR
FEERRIAAKFPMDFAARAYAAISGAAYVTMDKNEWQNDGSWICVVTIPAGMQEEFFNLANAAAKGDAQLKILE
>Mature_233_residues
MISLDDAVTARLETHGLKFELLVDPELADKMRHGEDLDIEDVVAAMYVYENASRGDKSPDEDLIKAFKTTDFTEIAKHII
LKGEIHLTTEQRRHLIEEKRRRVITFIARNAVNPQTGLPHPVMRIEMALDQVRINYDPFKSVDDLVKEAVKALRPILPIR
FEERRIAAKFPMDFAARAYAAISGAAYVTMDKNEWQNDGSWICVVTIPAGMQEEFFNLANAAAKGDAQLKILE

Specific function: Unknown

COG id: COG1500

COG function: function code J; Predicted exosome subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SDO1/SBDS family [H]

Homologues:

Organism=Homo sapiens, GI28416940, Length=231, Percent_Identity=26.8398268398268, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI25144459, Length=229, Percent_Identity=27.5109170305677, Blast_Score=87, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6323050, Length=160, Percent_Identity=26.875, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24659572, Length=176, Percent_Identity=28.4090909090909, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR018978
- InterPro:   IPR018023
- InterPro:   IPR019783
- InterPro:   IPR002140
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01172 SBDS; PF09377 SBDS_C [H]

EC number: NA

Molecular weight: Translated: 26423; Mature: 26423

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISLDDAVTARLETHGLKFELLVDPELADKMRHGEDLDIEDVVAAMYVYENASRGDKSPD
CCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCH
EDLIKAFKTTDFTEIAKHIILKGEIHLTTEQRRHLIEEKRRRVITFIARNAVNPQTGLPH
HHHHHHHCCCCHHHHHHHHEECCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PVMRIEMALDQVRINYDPFKSVDDLVKEAVKALRPILPIRFEERRIAAKFPMDFAARAYA
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEECCCHHHHHCCHHHHHHHHH
AISGAAYVTMDKNEWQNDGSWICVVTIPAGMQEEFFNLANAAAKGDAQLKILE
HHCCCEEEEECCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEC
>Mature Secondary Structure
MISLDDAVTARLETHGLKFELLVDPELADKMRHGEDLDIEDVVAAMYVYENASRGDKSPD
CCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCH
EDLIKAFKTTDFTEIAKHIILKGEIHLTTEQRRHLIEEKRRRVITFIARNAVNPQTGLPH
HHHHHHHCCCCHHHHHHHHEECCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PVMRIEMALDQVRINYDPFKSVDDLVKEAVKALRPILPIRFEERRIAAKFPMDFAARAYA
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEECCCHHHHHCCHHHHHHHHH
AISGAAYVTMDKNEWQNDGSWICVVTIPAGMQEEFFNLANAAAKGDAQLKILE
HHCCCEEEEECCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]