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The map label for this gene is yugS [H]

Identifier: 124486098

GI number: 124486098

Start: 1305951

End: 1307213

Strand: Reverse

Name: yugS [H]

Synonym: Mlab_1278

Alternate gene names: 124486098

Gene position: 1307213-1305951 (Counterclockwise)

Preceding gene: 124486099

Following gene: 124486093

Centisome position: 72.42

GC content: 49.56

Gene sequence:

>1263_bases
ATGGTAGTTTATACGAATATCATCATTTTTCTTATATTGCTGATTTGTTCGGCATTTTTTTCGGCTTCCGAAGTCGCTCT
TGTAGGTATCAGCCGTGCAAAAGTTCATACACTTTCAGAAACAGGAAGCCGCGGCAGGCGTCTGGATAAATTAAAAAATA
ATCCGGATCATTTTCTGATCACGATCCTGATCGGAAACAATATCGCAAACGTCGGGGCCGCATCTCTTGCGACCGCCGTT
GCTTTGGAATTATTCCAGAATAACGGCGTCGCGATCGCGACGGGAGTTGTCACCCTTCTGCTGCTGATATTTGGGGAGAT
AGGTCCAAAAACCTACGCCAATCGTCAGATGGAGCGGGTCGCACTGTTCGTTGCAACACCGATTTATTTCCTTACCATGC
TCCTCTCGCCGCTCTTCTATGTCTATGACCGGTTCCGGAAGAAGGATCATTCACCGTCCGTAACTGAAGAAGAGATCCGT
GAATGGATCGATGTCGGAGAGATGGAAGGGGCGATTGAAGAGGAAGAGAAGGAGATGATCTACTCGGTTCTCAAATTCAA
CGACACGACTGCAAAGGAGATCATGACGCCGAGGCCCGATGTTGCGGTTGTTGAGGATACGGTAACACTTGAAGAAGCGG
TATCCCATTTCAGGGAAACCGGTTTTTCGCGTGTACCGGTCTATCATGACAAAACCGACAATATTGTCGGAACCCTCAAC
TTCAAGGATCTCTTTAATGCCTACTCGACGGATAACCGCAAGGCCTCGGTCAAGAGCCTGATGCTTGACGTTTACTGCGT
GCCTGAATCGAAAAAGATCGATGTTCTTCTTCGTGAACTTCAGGTCAGGCGTGTTCATATGGCGATCGTTCTGGACGAGT
TCGGCGGATTTTCCGGTGTCGTGACCTTCGAGGACATTCTCGAGGAACTCGTCGGCGATATCATGGATGAATCCGACGGG
GATGAAGTCTCGGATATCATCCCGATCGGCGACGGTCTGTATATGATCGATGCCCAGGTCCGTGTGGCCCTGCTGAATGA
ACGGTTTGATATTTCACTGCCCGAAGATCCGGGTAATTACGAAACGATCGGCGGCCTCGTCTTCTCGCAGTTGGGTCATA
TCCCTCGTCTCGGAGAGTCGATCCCGCTCCCGGGAGATCATATTACCCTCGTTGTTACCAAGATGCGGGGTAGACAGATC
CTTAAAGTCAAGATGATTCTCGCCGCCCCTGAATATGACGATCAGGATATAAGCGGGGAGTAA

Upstream 100 bases:

>100_bases
TGTATTTAAGAAATGGTACGTATAAATAAATATAGAGATTTTAACCAATGGCTGTTTCCAGACATAAAAATAGATCTGCC
GCATATGCGGCGTGGACGTT

Downstream 100 bases:

>100_bases
TCCCCTTATATCTTAAATTTTAGCATAGATCTTCTTCCATTTTTCCACGATCCTGTAATGTGGATTTGCATTTAGAAGAA
GATCCCGCAGTATTTTTGGA

Product: aminotransferase class-III

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MVVYTNIIIFLILLICSAFFSASEVALVGISRAKVHTLSETGSRGRRLDKLKNNPDHFLITILIGNNIANVGAASLATAV
ALELFQNNGVAIATGVVTLLLLIFGEIGPKTYANRQMERVALFVATPIYFLTMLLSPLFYVYDRFRKKDHSPSVTEEEIR
EWIDVGEMEGAIEEEEKEMIYSVLKFNDTTAKEIMTPRPDVAVVEDTVTLEEAVSHFRETGFSRVPVYHDKTDNIVGTLN
FKDLFNAYSTDNRKASVKSLMLDVYCVPESKKIDVLLRELQVRRVHMAIVLDEFGGFSGVVTFEDILEELVGDIMDESDG
DEVSDIIPIGDGLYMIDAQVRVALLNERFDISLPEDPGNYETIGGLVFSQLGHIPRLGESIPLPGDHITLVVTKMRGRQI
LKVKMILAAPEYDDQDISGE

Sequences:

>Translated_420_residues
MVVYTNIIIFLILLICSAFFSASEVALVGISRAKVHTLSETGSRGRRLDKLKNNPDHFLITILIGNNIANVGAASLATAV
ALELFQNNGVAIATGVVTLLLLIFGEIGPKTYANRQMERVALFVATPIYFLTMLLSPLFYVYDRFRKKDHSPSVTEEEIR
EWIDVGEMEGAIEEEEKEMIYSVLKFNDTTAKEIMTPRPDVAVVEDTVTLEEAVSHFRETGFSRVPVYHDKTDNIVGTLN
FKDLFNAYSTDNRKASVKSLMLDVYCVPESKKIDVLLRELQVRRVHMAIVLDEFGGFSGVVTFEDILEELVGDIMDESDG
DEVSDIIPIGDGLYMIDAQVRVALLNERFDISLPEDPGNYETIGGLVFSQLGHIPRLGESIPLPGDHITLVVTKMRGRQI
LKVKMILAAPEYDDQDISGE
>Mature_420_residues
MVVYTNIIIFLILLICSAFFSASEVALVGISRAKVHTLSETGSRGRRLDKLKNNPDHFLITILIGNNIANVGAASLATAV
ALELFQNNGVAIATGVVTLLLLIFGEIGPKTYANRQMERVALFVATPIYFLTMLLSPLFYVYDRFRKKDHSPSVTEEEIR
EWIDVGEMEGAIEEEEKEMIYSVLKFNDTTAKEIMTPRPDVAVVEDTVTLEEAVSHFRETGFSRVPVYHDKTDNIVGTLN
FKDLFNAYSTDNRKASVKSLMLDVYCVPESKKIDVLLRELQVRRVHMAIVLDEFGGFSGVVTFEDILEELVGDIMDESDG
DEVSDIIPIGDGLYMIDAQVRVALLNERFDISLPEDPGNYETIGGLVFSQLGHIPRLGESIPLPGDHITLVVTKMRGRQI
LKVKMILAAPEYDDQDISGE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=377, Percent_Identity=28.9124668435013, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI94681046, Length=326, Percent_Identity=25.7668711656442, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI40068055, Length=338, Percent_Identity=26.0355029585799, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI40068053, Length=338, Percent_Identity=26.0355029585799, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI40068051, Length=248, Percent_Identity=24.1935483870968, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI145693175, Length=380, Percent_Identity=30.5263157894737, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI1786879, Length=282, Percent_Identity=32.2695035460993, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1790664, Length=412, Percent_Identity=24.5145631067961, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788119, Length=248, Percent_Identity=29.8387096774194, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI87082033, Length=234, Percent_Identity=27.3504273504274, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71980512, Length=360, Percent_Identity=25.8333333333333, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17554630, Length=361, Percent_Identity=23.5457063711911, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6324512, Length=335, Percent_Identity=26.865671641791, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 46783; Mature: 46783

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVYTNIIIFLILLICSAFFSASEVALVGISRAKVHTLSETGSRGRRLDKLKNNPDHFLI
CEEHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHEEEHHHCCCCCHHHHHHCCCCCEEEE
TILIGNNIANVGAASLATAVALELFQNNGVAIATGVVTLLLLIFGEIGPKTYANRQMERV
EEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ALFVATPIYFLTMLLSPLFYVYDRFRKKDHSPSVTEEEIREWIDVGEMEGAIEEEEKEMI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
YSVLKFNDTTAKEIMTPRPDVAVVEDTVTLEEAVSHFRETGFSRVPVYHDKTDNIVGTLN
HHHHHCCCCCHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEEE
FKDLFNAYSTDNRKASVKSLMLDVYCVPESKKIDVLLRELQVRRVHMAIVLDEFGGFSGV
HHHHHHHHCCCCCHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCE
VTFEDILEELVGDIMDESDGDEVSDIIPIGDGLYMIDAQVRVALLNERFDISLPEDPGNY
EEHHHHHHHHHHHHHCCCCCCCCHHEEECCCCEEEEEHHEEEEEECCCCEEECCCCCCCH
ETIGGLVFSQLGHIPRLGESIPLPGDHITLVVTKMRGRQILKVKMILAAPEYDDQDISGE
HHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MVVYTNIIIFLILLICSAFFSASEVALVGISRAKVHTLSETGSRGRRLDKLKNNPDHFLI
CEEHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHEEEHHHCCCCCHHHHHHCCCCCEEEE
TILIGNNIANVGAASLATAVALELFQNNGVAIATGVVTLLLLIFGEIGPKTYANRQMERV
EEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ALFVATPIYFLTMLLSPLFYVYDRFRKKDHSPSVTEEEIREWIDVGEMEGAIEEEEKEMI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
YSVLKFNDTTAKEIMTPRPDVAVVEDTVTLEEAVSHFRETGFSRVPVYHDKTDNIVGTLN
HHHHHCCCCCHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEEE
FKDLFNAYSTDNRKASVKSLMLDVYCVPESKKIDVLLRELQVRRVHMAIVLDEFGGFSGV
HHHHHHHHCCCCCHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCE
VTFEDILEELVGDIMDESDGDEVSDIIPIGDGLYMIDAQVRVALLNERFDISLPEDPGNY
EEHHHHHHHHHHHHHCCCCCCCCHHEEECCCCEEEEEHHEEEEEECCCCEEECCCCCCCH
ETIGGLVFSQLGHIPRLGESIPLPGDHITLVVTKMRGRQILKVKMILAAPEYDDQDISGE
HHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]