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The map label for this gene is 124485363

Identifier: 124485363

GI number: 124485363

Start: 511513

End: 512448

Strand: Reverse

Name: 124485363

Synonym: Mlab_0538

Alternate gene names: NA

Gene position: 512448-511513 (Counterclockwise)

Preceding gene: 124485364

Following gene: 124485362

Centisome position: 28.39

GC content: 52.56

Gene sequence:

>936_bases
ATGCCACGAAAACGACCAGTATCCAAAACCCCGAAAACCTGCCTTCACCGGCAGGGATACAACTTCATAGCTGAAGGAGC
ATCCGCCGCCGTCAAGCCGTGCATGTGGTGCAAACGTGCTCTTCGCGGCGGCGAATCCTGCTATAAACACCAGTTCTACG
GGATCGACACCTGGAAATGCGTCCAGATGACCCCGACGCTGCGCTGCAATCAGCGGTGTCTTTTTTGCTGGAGATCCATG
GAGCACGAGATCCTGTCCGAGACTGAACTATCTCCGGAAGAAATCGTCGCCGCCATTCCAAAGATGCAGAAAAAAGGCTT
GTCCGGCGACAAACCTTATACCGAGCCGGAGAGGTGGGAAGAGGCGACCGATCACCCGACCCAGTATGCGCTCTCTTTGT
CCGGCGAGCCGACCCTTTACTCGAAACTGCCCGAACTCATCGACCTTCTCCGGGAAAATCCCAACAACAGCGTGTTCGTT
GTTTCAAACGGAACGATGCCTTCCGTGATCCGGCGGATACGCCCGACCCAGTTGTATCTGTCTCTGGATGCCGTGGACGA
ATCCTCTTATGAAAGGATATGCCGTCCGATCGGCGATCCGGCTGCCATGTGGGGGAATATCCAAACGTCTCTTTCGCTTC
TCAAACAAAAAGAGGAGGAGGGCGTCAGAACGGCGGTCCGGATCACCCTCGTCAACGAGTATAATGACACCTATGAGGCA
GGTTTTGCCAAAATTATCGAAGAGGCACAGCCCCTCTTTGTTGAAGTAAAGGGATACATGTATTTGGGATACAGTCGAAT
GAGATTAACAGAAATGCATGTCCCCGACATGGAAACCATTCGTCGTTTCGCCGCAGGAGTTGCCCAACTCTGCAATTATG
AGATTATGGATGAAAACGTGCCGAGCCGCGTTGTTTGTCTGAAGAGAAAATCATGA

Upstream 100 bases:

>100_bases
TCGCCGCTCTGTTGAGGTATAAGATCTGATTCTTCCGGCACTCCAAAATGACTTCCCATGTGTATATACAATCACAAATA
ATACAGGACATTTGATACCA

Downstream 100 bases:

>100_bases
AATTCGATATTGAGGAATTCAAGGAACGCAGAAAAACCGATTTCGAGGGTGCCTGGCATGCCGGCCCATCGGTCATAACC
CCGCCGGAATCATCAAAAAT

Product: tRNA-modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MPRKRPVSKTPKTCLHRQGYNFIAEGASAAVKPCMWCKRALRGGESCYKHQFYGIDTWKCVQMTPTLRCNQRCLFCWRSM
EHEILSETELSPEEIVAAIPKMQKKGLSGDKPYTEPERWEEATDHPTQYALSLSGEPTLYSKLPELIDLLRENPNNSVFV
VSNGTMPSVIRRIRPTQLYLSLDAVDESSYERICRPIGDPAAMWGNIQTSLSLLKQKEEEGVRTAVRITLVNEYNDTYEA
GFAKIIEEAQPLFVEVKGYMYLGYSRMRLTEMHVPDMETIRRFAAGVAQLCNYEIMDENVPSRVVCLKRKS

Sequences:

>Translated_311_residues
MPRKRPVSKTPKTCLHRQGYNFIAEGASAAVKPCMWCKRALRGGESCYKHQFYGIDTWKCVQMTPTLRCNQRCLFCWRSM
EHEILSETELSPEEIVAAIPKMQKKGLSGDKPYTEPERWEEATDHPTQYALSLSGEPTLYSKLPELIDLLRENPNNSVFV
VSNGTMPSVIRRIRPTQLYLSLDAVDESSYERICRPIGDPAAMWGNIQTSLSLLKQKEEEGVRTAVRITLVNEYNDTYEA
GFAKIIEEAQPLFVEVKGYMYLGYSRMRLTEMHVPDMETIRRFAAGVAQLCNYEIMDENVPSRVVCLKRKS
>Mature_310_residues
PRKRPVSKTPKTCLHRQGYNFIAEGASAAVKPCMWCKRALRGGESCYKHQFYGIDTWKCVQMTPTLRCNQRCLFCWRSME
HEILSETELSPEEIVAAIPKMQKKGLSGDKPYTEPERWEEATDHPTQYALSLSGEPTLYSKLPELIDLLRENPNNSVFVV
SNGTMPSVIRRIRPTQLYLSLDAVDESSYERICRPIGDPAAMWGNIQTSLSLLKQKEEEGVRTAVRITLVNEYNDTYEAG
FAKIIEEAQPLFVEVKGYMYLGYSRMRLTEMHVPDMETIRRFAAGVAQLCNYEIMDENVPSRVVCLKRKS

Specific function: Unknown

COG id: COG0731

COG function: function code C; Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0026 family [H]

Homologues:

Organism=Homo sapiens, GI50726981, Length=317, Percent_Identity=35.0157728706625, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI224282123, Length=261, Percent_Identity=32.9501915708812, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI224282125, Length=264, Percent_Identity=31.8181818181818, Blast_Score=108, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6325049, Length=282, Percent_Identity=32.6241134751773, Blast_Score=132, Evalue=8e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR007197
- InterPro:   IPR013917 [H]

Pfam domain/function: PF04055 Radical_SAM; PF08608 Wyosine_form [H]

EC number: NA

Molecular weight: Translated: 35608; Mature: 35477

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRKRPVSKTPKTCLHRQGYNFIAEGASAAVKPCMWCKRALRGGESCYKHQFYGIDTWKC
CCCCCCCCCCHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEE
VQMTPTLRCNQRCLFCWRSMEHEILSETELSPEEIVAAIPKMQKKGLSGDKPYTEPERWE
EEECCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
EATDHPTQYALSLSGEPTLYSKLPELIDLLRENPNNSVFVVSNGTMPSVIRRIRPTQLYL
HHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHCCCCEEEE
SLDAVDESSYERICRPIGDPAAMWGNIQTSLSLLKQKEEEGVRTAVRITLVNEYNDTYEA
EEECCCCHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCCHHHH
GFAKIIEEAQPLFVEVKGYMYLGYSRMRLTEMHVPDMETIRRFAAGVAQLCNYEIMDENV
HHHHHHHHCCCEEEEEECEEEECHHHHEEEECCCCCHHHHHHHHHHHHHHHCCHHHCCCC
PSRVVCLKRKS
CCEEEEEECCC
>Mature Secondary Structure 
PRKRPVSKTPKTCLHRQGYNFIAEGASAAVKPCMWCKRALRGGESCYKHQFYGIDTWKC
CCCCCCCCCHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEE
VQMTPTLRCNQRCLFCWRSMEHEILSETELSPEEIVAAIPKMQKKGLSGDKPYTEPERWE
EEECCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
EATDHPTQYALSLSGEPTLYSKLPELIDLLRENPNNSVFVVSNGTMPSVIRRIRPTQLYL
HHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHCCCCEEEE
SLDAVDESSYERICRPIGDPAAMWGNIQTSLSLLKQKEEEGVRTAVRITLVNEYNDTYEA
EEECCCCHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCCHHHH
GFAKIIEEAQPLFVEVKGYMYLGYSRMRLTEMHVPDMETIRRFAAGVAQLCNYEIMDENV
HHHHHHHHCCCEEEEEECEEEECHHHHEEEECCCCCHHHHHHHHHHHHHHHCCHHHCCCC
PSRVVCLKRKS
CCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]