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The map label for this gene is pelA

Identifier: 124485364

GI number: 124485364

Start: 512520

End: 513548

Strand: Reverse

Name: pelA

Synonym: Mlab_0539

Alternate gene names: 124485364

Gene position: 513548-512520 (Counterclockwise)

Preceding gene: 124485365

Following gene: 124485363

Centisome position: 28.45

GC content: 59.57

Gene sequence:

>1029_bases
ATGAAGGCGGAGCTGCCCGAACCGCTGAAAAAAGACGGATTCGGCGAGTATAAACTCATGCCCGAATCGATCGACGATCT
CTGGCATCTTTCGCATCTGATAAGTCCCGGAAACACCGTGTATGCCGTCACGCTGAGGACAGTGGACGGCCCGTCCGACA
AACTCCGTTCCGAAAAGCTCGAGAAGCGGCCGGTGCGGATCGGGGTGAAATGCGAGAAGGCGGAGTTCGTCCCGGAATCG
TCCCGCCTCAGAGTGTTTGGGGTCATCAGTTACGGGCCGGACATGGGCCAGCACCACACGCTCAATATCGAAGCAGGCTA
TGAAATAAGCGTTGTTCGGCAGTGGCGGCAGATCGATCTTGCCCGTCTGGAACGGGCGGTCTCCTCTTCGGTCCACGGTG
TGGTTCACATCGCGGCGATTGAGGATGGGGAGGCGGAACTCTATCGGGTCAGGCAGTACGGACCCGAGCGGATCACTACG
CTGACGGTCGGCAGCGGAAAAACCGCCGAGCTGGACTCAAGGCAGGCCCTGTTTGCCGAGCTCCTCACATTTCTCGAGAA
GGTCACCGGCTCGATCGTTATCGCCGGCCCGGGATTCGTAAAAGAAGACTTCGTCAAGTTCGCAAAAACCAAAGCTCCCG
AGATCGCCGAACGCATGCTCATCGCCGACACAAGGCGCTGCGGCTACGGGGCGGTTCAGGAGGCGATCGGAAACGGCGTC
CTTACCCGCGTGGCAGAGGATCTCCAGCTCGCAAAAGAGGTCTCGTTCATGGACGAGGTGTTTCTCCGGATCGGGCAGAA
CGGCGCCGTCGCCTACGGAAAAAGCGAGGTACGCCAGGCGATCGATTACGGAGCAGCCGAGACGATCCTTGTGGCCGACT
CGTTTGTAAAAGACGGCGGCATCGAAAAAATGATCGAAGGGGCAGAGCGGCTCGGCGCGAACGTCGTCGTCCTCTCGACC
GAGTTCGAACCGGGCACCCGGCTTGTTGGTCTCGGCGGGGTCGCCGCTCTGTTGAGGTATAAGATCTGA

Upstream 100 bases:

>100_bases
AAGCGCTCAAAGCGATCCTGAACACCGAGGGCGTAGCCGCGTTCGTGCCGCCGGGCGGGTCCGATCTCAAAGAGCCGGCC
CGAGAGGGAGCGGACCGCGA

Downstream 100 bases:

>100_bases
TTCTTCCGGCACTCCAAAATGACTTCCCATGTGTATATACAATCACAAATAATACAGGACATTTGATACCAATGCCACGA
AAACGACCAGTATCCAAAAC

Product: cell division protein pelota

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MKAELPEPLKKDGFGEYKLMPESIDDLWHLSHLISPGNTVYAVTLRTVDGPSDKLRSEKLEKRPVRIGVKCEKAEFVPES
SRLRVFGVISYGPDMGQHHTLNIEAGYEISVVRQWRQIDLARLERAVSSSVHGVVHIAAIEDGEAELYRVRQYGPERITT
LTVGSGKTAELDSRQALFAELLTFLEKVTGSIVIAGPGFVKEDFVKFAKTKAPEIAERMLIADTRRCGYGAVQEAIGNGV
LTRVAEDLQLAKEVSFMDEVFLRIGQNGAVAYGKSEVRQAIDYGAAETILVADSFVKDGGIEKMIEGAERLGANVVVLST
EFEPGTRLVGLGGVAALLRYKI

Sequences:

>Translated_342_residues
MKAELPEPLKKDGFGEYKLMPESIDDLWHLSHLISPGNTVYAVTLRTVDGPSDKLRSEKLEKRPVRIGVKCEKAEFVPES
SRLRVFGVISYGPDMGQHHTLNIEAGYEISVVRQWRQIDLARLERAVSSSVHGVVHIAAIEDGEAELYRVRQYGPERITT
LTVGSGKTAELDSRQALFAELLTFLEKVTGSIVIAGPGFVKEDFVKFAKTKAPEIAERMLIADTRRCGYGAVQEAIGNGV
LTRVAEDLQLAKEVSFMDEVFLRIGQNGAVAYGKSEVRQAIDYGAAETILVADSFVKDGGIEKMIEGAERLGANVVVLST
EFEPGTRLVGLGGVAALLRYKI
>Mature_342_residues
MKAELPEPLKKDGFGEYKLMPESIDDLWHLSHLISPGNTVYAVTLRTVDGPSDKLRSEKLEKRPVRIGVKCEKAEFVPES
SRLRVFGVISYGPDMGQHHTLNIEAGYEISVVRQWRQIDLARLERAVSSSVHGVVHIAAIEDGEAELYRVRQYGPERITT
LTVGSGKTAELDSRQALFAELLTFLEKVTGSIVIAGPGFVKEDFVKFAKTKAPEIAERMLIADTRRCGYGAVQEAIGNGV
LTRVAEDLQLAKEVSFMDEVFLRIGQNGAVAYGKSEVRQAIDYGAAETILVADSFVKDGGIEKMIEGAERLGANVVVLST
EFEPGTRLVGLGGVAALLRYKI

Specific function: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has end

COG id: COG1537

COG function: function code R; Predicted RNA-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eukaryotic release factor 1 family. Pelota subfamily

Homologues:

Organism=Homo sapiens, GI31880783, Length=366, Percent_Identity=21.8579234972678, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17554648, Length=377, Percent_Identity=24.4031830238727, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324327, Length=381, Percent_Identity=22.0472440944882, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI17136914, Length=357, Percent_Identity=24.6498599439776, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PELO_METLZ (A2SQV7)

Other databases:

- EMBL:   CP000559
- RefSeq:   YP_001029980.1
- ProteinModelPortal:   A2SQV7
- SMR:   A2SQV7
- STRING:   A2SQV7
- GeneID:   4794737
- GenomeReviews:   CP000559_GR
- KEGG:   mla:Mlab_0539
- eggNOG:   arNOG04486
- HOGENOM:   HBG646058
- OMA:   WHLSHLI
- PhylomeDB:   A2SQV7
- ProtClustDB:   CLSK949438
- BioCyc:   MLAB410358:MLAB_0539-MONOMER
- GO:   GO:0005737
- GO:   GO:0006412
- HAMAP:   MF_01853
- InterPro:   IPR005140
- InterPro:   IPR005141
- InterPro:   IPR005142
- InterPro:   IPR004405
- PANTHER:   PTHR10853
- TIGRFAMs:   TIGR00111

Pfam domain/function: PF03463 eRF1_1; PF03464 eRF1_2; PF03465 eRF1_3

EC number: NA

Molecular weight: Translated: 37478; Mature: 37478

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAELPEPLKKDGFGEYKLMPESIDDLWHLSHLISPGNTVYAVTLRTVDGPSDKLRSEKL
CCCCCCCCHHHCCCCCEEECHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHH
EKRPVRIGVKCEKAEFVPESSRLRVFGVISYGPDMGQHHTLNIEAGYEISVVRQWRQIDL
HCCCCEEEEEEECCCCCCCCCCEEEEEEEECCCCCCCEEEEEEECCCEEHHHHHHHHHHH
ARLERAVSSSVHGVVHIAAIEDGEAELYRVRQYGPERITTLTVGSGKTAELDSRQALFAE
HHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHH
LLTFLEKVTGSIVIAGPGFVKEDFVKFAKTKAPEIAERMLIADTRRCGYGAVQEAIGNGV
HHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHCCHH
LTRVAEDLQLAKEVSFMDEVFLRIGQNGAVAYGKSEVRQAIDYGAAETILVADSFVKDGG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHCCCCCEEEEEHHHHCCCC
IEKMIEGAERLGANVVVLSTEFEPGTRLVGLGGVAALLRYKI
HHHHHHHHHHCCCEEEEEEECCCCCCEEEECHHHHHHHHCCC
>Mature Secondary Structure
MKAELPEPLKKDGFGEYKLMPESIDDLWHLSHLISPGNTVYAVTLRTVDGPSDKLRSEKL
CCCCCCCCHHHCCCCCEEECHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHH
EKRPVRIGVKCEKAEFVPESSRLRVFGVISYGPDMGQHHTLNIEAGYEISVVRQWRQIDL
HCCCCEEEEEEECCCCCCCCCCEEEEEEEECCCCCCCEEEEEEECCCEEHHHHHHHHHHH
ARLERAVSSSVHGVVHIAAIEDGEAELYRVRQYGPERITTLTVGSGKTAELDSRQALFAE
HHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHH
LLTFLEKVTGSIVIAGPGFVKEDFVKFAKTKAPEIAERMLIADTRRCGYGAVQEAIGNGV
HHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHCCHH
LTRVAEDLQLAKEVSFMDEVFLRIGQNGAVAYGKSEVRQAIDYGAAETILVADSFVKDGG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHCCCCCEEEEEHHHHCCCC
IEKMIEGAERLGANVVVLSTEFEPGTRLVGLGGVAALLRYKI
HHHHHHHHHHCCCEEEEEEECCCCCCEEEECHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA