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The map label for this gene is dapB

Identifier: 124485354

GI number: 124485354

Start: 503024

End: 503779

Strand: Reverse

Name: dapB

Synonym: Mlab_0529

Alternate gene names: 124485354

Gene position: 503779-503024 (Counterclockwise)

Preceding gene: 124485355

Following gene: 124485353

Centisome position: 27.91

GC content: 57.54

Gene sequence:

>756_bases
ATGATTAAGGTCATCATCTGCGGCGCACTCGGCAGGATGGGAACCATGATCGCGAACATGGTGATCGAGAACCCGGAGCT
GGAGTTCGTCGGCGGCGTGGATATCCGGGACGGGACGGTCCTTGGAAAACCGGTCGTTCCTTCCGAGAAGCTTGCCGCGT
TCATCGACGAGGTCAAACCCGATGTGATGATCGACTTCACCGTGGCGGCGGCGACGATGATCAATGCAAAGATCGCTGCG
AAAAAAGGCGTGGCTTTAGTGATCGGCACGACCGGTTTCACGCCGGAGCAGGATGCCGAGCTGCTTGACGCGATAAAGAA
TGTCCCGGTCGTTAAAACGACCAACTTCAGCGTCGGCGTGAACATTTTCTGGGAACTTGTCCGCGATGCGGCATCGCGTC
TGGGCGATTACGATATCGAAGTGATCGAGGCCCACCACCGGTACAAGAAGGACGCTCCGAGCGGAACGGCGAAGACGATC
CTGAAAGTGATCCAGGAAGAGGTCGGCAAACGCGAGGAGATGTACGGACGCGAGGGTATGACCGAGCGGAAAAACGAGAT
CGGCGTGCATGTGATCCGCGGCGGCGATGTGGTCGGCGACCACACGGTCCAGTTCCATCAGAACTACGAGACGATCGAGC
TGACGCACCGTGCCTACGATAGAGCGGTATTCGCACGAGGCGCTATCCGTGCGGCGGCATGGGTGCCCAAAGCGAAACCG
GGAGTATATACTATGAAAGAGGTTCTCGGGTTATAA

Upstream 100 bases:

>100_bases
GCAGAGATCCGCGGTCTGATCAACTCAGGCAACGTCAGACTTCCATTGGATTCGCTTGGCGAGCAGAACACGGCGATCCT
TCGCGGGGTGCTTTCCCGCT

Downstream 100 bases:

>100_bases
CCCGGGCCTTCTTTTTTCGATATCCATATCTTTCCCAATCCAAATCATTTTTTATTTCAGTTACTTTGAACACCGACTGG
AAAAGAGCAGCCCTTCACCA

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MIKVIICGALGRMGTMIANMVIENPELEFVGGVDIRDGTVLGKPVVPSEKLAAFIDEVKPDVMIDFTVAAATMINAKIAA
KKGVALVIGTTGFTPEQDAELLDAIKNVPVVKTTNFSVGVNIFWELVRDAASRLGDYDIEVIEAHHRYKKDAPSGTAKTI
LKVIQEEVGKREEMYGREGMTERKNEIGVHVIRGGDVVGDHTVQFHQNYETIELTHRAYDRAVFARGAIRAAAWVPKAKP
GVYTMKEVLGL

Sequences:

>Translated_251_residues
MIKVIICGALGRMGTMIANMVIENPELEFVGGVDIRDGTVLGKPVVPSEKLAAFIDEVKPDVMIDFTVAAATMINAKIAA
KKGVALVIGTTGFTPEQDAELLDAIKNVPVVKTTNFSVGVNIFWELVRDAASRLGDYDIEVIEAHHRYKKDAPSGTAKTI
LKVIQEEVGKREEMYGREGMTERKNEIGVHVIRGGDVVGDHTVQFHQNYETIELTHRAYDRAVFARGAIRAAAWVPKAKP
GVYTMKEVLGL
>Mature_251_residues
MIKVIICGALGRMGTMIANMVIENPELEFVGGVDIRDGTVLGKPVVPSEKLAAFIDEVKPDVMIDFTVAAATMINAKIAA
KKGVALVIGTTGFTPEQDAELLDAIKNVPVVKTTNFSVGVNIFWELVRDAASRLGDYDIEVIEAHHRYKKDAPSGTAKTI
LKVIQEEVGKREEMYGREGMTERKNEIGVHVIRGGDVVGDHTVQFHQNYETIELTHRAYDRAVFARGAIRAAAWVPKAKP
GVYTMKEVLGL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=271, Percent_Identity=38.7453874538745, Blast_Score=151, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_METLZ (A2SQU7)

Other databases:

- EMBL:   CP000559
- RefSeq:   YP_001029970.1
- ProteinModelPortal:   A2SQU7
- SMR:   A2SQU7
- STRING:   A2SQU7
- GeneID:   4795079
- GenomeReviews:   CP000559_GR
- KEGG:   mla:Mlab_0529
- eggNOG:   arNOG05038
- HOGENOM:   HBG594002
- OMA:   YNNENIE
- PhylomeDB:   A2SQU7
- ProtClustDB:   PRK00048
- BioCyc:   MLAB410358:MLAB_0529-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 27432; Mature: 27432

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVIICGALGRMGTMIANMVIENPELEFVGGVDIRDGTVLGKPVVPSEKLAAFIDEVKP
CEEEEEECCHHHHHHHHHHHHCCCCCEEEECCEECCCCEEECCCCCCHHHHHHHHHHCCC
DVMIDFTVAAATMINAKIAAKKGVALVIGTTGFTPEQDAELLDAIKNVPVVKTTNFSVGV
CEEEEHHHHHHHHHHHHHECCCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEECCCEEHH
NIFWELVRDAASRLGDYDIEVIEAHHRYKKDAPSGTAKTILKVIQEEVGKREEMYGREGM
HHHHHHHHHHHHHCCCCCCEEHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHCCCCC
TERKNEIGVHVIRGGDVVGDHTVQFHQNYETIELTHRAYDRAVFARGAIRAAAWVPKAKP
CCCCCCCCEEEEECCCEECCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCC
GVYTMKEVLGL
CHHHHHHHHCC
>Mature Secondary Structure
MIKVIICGALGRMGTMIANMVIENPELEFVGGVDIRDGTVLGKPVVPSEKLAAFIDEVKP
CEEEEEECCHHHHHHHHHHHHCCCCCEEEECCEECCCCEEECCCCCCHHHHHHHHHHCCC
DVMIDFTVAAATMINAKIAAKKGVALVIGTTGFTPEQDAELLDAIKNVPVVKTTNFSVGV
CEEEEHHHHHHHHHHHHHECCCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEECCCEEHH
NIFWELVRDAASRLGDYDIEVIEAHHRYKKDAPSGTAKTILKVIQEEVGKREEMYGREGM
HHHHHHHHHHHHHCCCCCCEEHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHCCCCC
TERKNEIGVHVIRGGDVVGDHTVQFHQNYETIELTHRAYDRAVFARGAIRAAAWVPKAKP
CCCCCCCCEEEEECCCEECCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCC
GVYTMKEVLGL
CHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA