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The map label for this gene is 124485104

Identifier: 124485104

GI number: 124485104

Start: 256673

End: 257440

Strand: Reverse

Name: 124485104

Synonym: Mlab_0277

Alternate gene names: NA

Gene position: 257440-256673 (Counterclockwise)

Preceding gene: 124485108

Following gene: 124485103

Centisome position: 14.26

GC content: 48.31

Gene sequence:

>768_bases
ATGGATTTGGAAGTAACCAAAGCAATCACAGAATCCTGGTTTGCAAGACTGCAGGAAAATCTGTGTTTCGATGCAGCAAT
TGTTGGAACAGGACCATCCGGACTTATCGCCGCAGTAAAACTCGCAGATGCAGGATATAAAGTCTCCATGTTTGAAAGTA
AACTTGCTCCAGGAGGAGGGATGTGGGGAGGCGCCATGCTGTTTTCATCCATAGCTGTTCAGAATGAAGCGGTGTATCTT
TTGGACGAACTGGAAATTCCCTACAAACGATACAACGAGAATCTCGTTGTCTGCGACAGTGTTCTCGCAACCTCGGCACT
GATATATCAGGCGTCCAAAAGAGGGGTTGTGATTCACAACGGTATGAGCGTTGAGGATGTGGTGTTTATGGATAACAGAG
TTTCAGGCGTTGTTGTGAACTGGGGTCCGGTTGTAAGAGAAGGGCTGCATGTAGATCCGCTTTCCTTCAGAGCAAAAATC
GTGGTGGATGCAACCGGCCATCCCTGTATGATCTCGGAAACTGCTGCAAGAAAGAACAACATCACCCTTAACACACCGAC
TGGAAAAGTCTGCGGCGAGTGTTCTTTGAACGCGGTCGAGGGAGAGGCAATGACTGTTGAAAATACCAAAGAGATCTATC
CTGGACTCTACGTCTGCGGGATGGCAGCAAACGGAGTGTTTGGATCGCCCCGTATGGGACCGATCTTCGGTGGGATGCTT
CTTTCAGGAGAGAAAGTGGCAAAACTGATTATCGAGGAGCTGAAGTGA

Upstream 100 bases:

>100_bases
TTATACCCATATAACCTGATCCGGGTAATGCCGGCGGAGGGAGTCGCTTTTCCTATACGTGACCGTGCATTATCCGCCCA
GATTCAGGGAGGATAACACA

Downstream 100 bases:

>100_bases
CGGCAAACAATTTTGGGTTGTATCTGATCATCACCAAACCCTCTTTTTCCTACAGGAAAATCGCCGAAACCGCGGTTAAG
TATAATGTGCAGTATCTTCA

Product: ribulose-1,5-biphosphate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MDLEVTKAITESWFARLQENLCFDAAIVGTGPSGLIAAVKLADAGYKVSMFESKLAPGGGMWGGAMLFSSIAVQNEAVYL
LDELEIPYKRYNENLVVCDSVLATSALIYQASKRGVVIHNGMSVEDVVFMDNRVSGVVVNWGPVVREGLHVDPLSFRAKI
VVDATGHPCMISETAARKNNITLNTPTGKVCGECSLNAVEGEAMTVENTKEIYPGLYVCGMAANGVFGSPRMGPIFGGML
LSGEKVAKLIIEELK

Sequences:

>Translated_255_residues
MDLEVTKAITESWFARLQENLCFDAAIVGTGPSGLIAAVKLADAGYKVSMFESKLAPGGGMWGGAMLFSSIAVQNEAVYL
LDELEIPYKRYNENLVVCDSVLATSALIYQASKRGVVIHNGMSVEDVVFMDNRVSGVVVNWGPVVREGLHVDPLSFRAKI
VVDATGHPCMISETAARKNNITLNTPTGKVCGECSLNAVEGEAMTVENTKEIYPGLYVCGMAANGVFGSPRMGPIFGGML
LSGEKVAKLIIEELK
>Mature_255_residues
MDLEVTKAITESWFARLQENLCFDAAIVGTGPSGLIAAVKLADAGYKVSMFESKLAPGGGMWGGAMLFSSIAVQNEAVYL
LDELEIPYKRYNENLVVCDSVLATSALIYQASKRGVVIHNGMSVEDVVFMDNRVSGVVVNWGPVVREGLHVDPLSFRAKI
VVDATGHPCMISETAARKNNITLNTPTGKVCGECSLNAVEGEAMTVENTKEIYPGLYVCGMAANGVFGSPRMGPIFGGML
LSGEKVAKLIIEELK

Specific function: Involved in biosynthesis of the thiamine precursor thiazole [H]

COG id: COG1635

COG function: function code H; Flavoprotein involved in thiazole biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the THI4 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321583, Length=278, Percent_Identity=30.9352517985612, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR003042
- InterPro:   IPR002922
- InterPro:   IPR022828 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 27257; Mature: 27257

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLEVTKAITESWFARLQENLCFDAAIVGTGPSGLIAAVKLADAGYKVSMFESKLAPGGG
CCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEECCCEEEEEHHHHCCCCCC
MWGGAMLFSSIAVQNEAVYLLDELEIPYKRYNENLVVCDSVLATSALIYQASKRGVVIHN
CHHHHHHHHHHHHCCCEEEEEECCCCCHHHCCCCEEEEHHHHHHHHHHEECCCCCEEEEC
GMSVEDVVFMDNRVSGVVVNWGPVVREGLHVDPLSFRAKIVVDATGHPCMISETAARKNN
CCCEEEEEEECCCCCEEEEECCHHHHCCCCCCCCCEEEEEEEECCCCCEEEEHHHCCCCC
ITLNTPTGKVCGECSLNAVEGEAMTVENTKEIYPGLYVCGMAANGVFGSPRMGPIFGGML
EEEECCCCCCCCCCCCEEECCCEEEECCCHHHCCCEEEEEEECCCCCCCCCCCHHHCCEE
LSGEKVAKLIIEELK
ECCHHHHHHHHHHCC
>Mature Secondary Structure
MDLEVTKAITESWFARLQENLCFDAAIVGTGPSGLIAAVKLADAGYKVSMFESKLAPGGG
CCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEECCCEEEEEHHHHCCCCCC
MWGGAMLFSSIAVQNEAVYLLDELEIPYKRYNENLVVCDSVLATSALIYQASKRGVVIHN
CHHHHHHHHHHHHCCCEEEEEECCCCCHHHCCCCEEEEHHHHHHHHHHEECCCCCEEEEC
GMSVEDVVFMDNRVSGVVVNWGPVVREGLHVDPLSFRAKIVVDATGHPCMISETAARKNN
CCCEEEEEEECCCCCEEEEECCHHHHCCCCCCCCCEEEEEEEECCCCCEEEEHHHCCCCC
ITLNTPTGKVCGECSLNAVEGEAMTVENTKEIYPGLYVCGMAANGVFGSPRMGPIFGGML
EEEECCCCCCCCCCCCEEECCCEEEECCCHHHCCCEEEEEEECCCCCCCCCCCHHHCCEE
LSGEKVAKLIIEELK
ECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA