Click here to switch to the map view.

The map label for this gene is nahR [H]

Identifier: 124265993

GI number: 124265993

Start: 837535

End: 838515

Strand: Direct

Name: nahR [H]

Synonym: Mpe_A0800

Alternate gene names: 124265993

Gene position: 837535-838515 (Clockwise)

Preceding gene: 124265989

Following gene: 124265994

Centisome position: 20.71

GC content: 73.09

Gene sequence:

>981_bases
ATGAGCCAGCCCACGCTTTTCGACAAGATCGAGCTCCATCTCGTCCGCGTCCTCCACACCGTGATCACCGAACGCAGCGT
GTCGCGTGCCGCACTCAGGCTGCGCACCACCCAGCCGGCCGTCAGCGCCCAGCTCAAGCGCCTGCGGGCGCTGGTCGGCG
ACCCGTTGTTGGTGCGCTCCGGCACCGGCATGGCGCCGACCGCGGTGGCGCTGCAACTGCTGGAGCCGGCGGCAGAGCTG
CTGCGCAACGCCGAGCGGTTGTTCGGCTCGCGCGCCGAGGCGCTGGCCTTCGACCCGGCGCACAGCGAGACGACCTTCCG
CGTGGCGGCGAGCGACTATCTCGACCCGCAGTTCCTGCCCGCGCTCGTGACGCGGCTGCGCGCCGAGGCGCCGGGCATCC
GCGTTGAGGTGCTGCCGCTGTCGGCCGAGTTCGACTACCGCAAGGGCCTGGCGCGCGGCGAGGTCGACCTGGTGATCGGA
AACTGGCTGCGGCCACCGGCCGAGCTGCACCTGGGCCGCCTGCTGTCCGACGAGATCGTCTGCCTGGTCGCCGAGGACCA
CCCGGCCGTGAAGAGCCCGCGCAGCTGGACCGCCGAGCGCTACCTGGCCAGCGAGCACATCGCGCCGACGCCGCTGCACC
CCGGTGCGCGCGGCGTGATCGACGAGCACCTCGACGCGCTGGGTCTGGCGCGCGACATCGTGGTGCGCAGCCCCTACTTC
GGCCTGGGGCCGCAGATGGTGGCGCACTCGCGGCTGGTGCTCACCACCGGCCGGTTGTTCTGCAGCCGCTACGTCGGTCA
GCTGCCGGGCCTGCGCATCGTGCGCTGCCCGGTGCCGTTCCCGGCGCTGGTGTACTACCAGCTCTGGCACGAGCTGAGCC
ACCAGTCGGCCGCCGGTCGGTGGCTGCGCGGCGTGATGCGCGATGTGGCGCGCGGCCTGCCGAAGCCGGGTGCCGCGGCC
CCGCGCGCCGGCGCTCACTGA

Upstream 100 bases:

>100_bases
CGGGGCGCGGTCTGACGAATCTTGCGGTTCGGGCCGAAGGTACTCCACGCCGACCCCATGCGAATACGATGCCAGCGATA
ACCGGTATGCCGATGACGAT

Downstream 100 bases:

>100_bases
TGACCACGCAAGGGAGCACCGCATGAGCCAAAGGCTGGCCCTGTTCGGCGACCTGCTCGACATCGAGGTCGACCCCGGCT
TCGCTGCCCCTGGCGACGCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MSQPTLFDKIELHLVRVLHTVITERSVSRAALRLRTTQPAVSAQLKRLRALVGDPLLVRSGTGMAPTAVALQLLEPAAEL
LRNAERLFGSRAEALAFDPAHSETTFRVAASDYLDPQFLPALVTRLRAEAPGIRVEVLPLSAEFDYRKGLARGEVDLVIG
NWLRPPAELHLGRLLSDEIVCLVAEDHPAVKSPRSWTAERYLASEHIAPTPLHPGARGVIDEHLDALGLARDIVVRSPYF
GLGPQMVAHSRLVLTTGRLFCSRYVGQLPGLRIVRCPVPFPALVYYQLWHELSHQSAAGRWLRGVMRDVARGLPKPGAAA
PRAGAH

Sequences:

>Translated_326_residues
MSQPTLFDKIELHLVRVLHTVITERSVSRAALRLRTTQPAVSAQLKRLRALVGDPLLVRSGTGMAPTAVALQLLEPAAEL
LRNAERLFGSRAEALAFDPAHSETTFRVAASDYLDPQFLPALVTRLRAEAPGIRVEVLPLSAEFDYRKGLARGEVDLVIG
NWLRPPAELHLGRLLSDEIVCLVAEDHPAVKSPRSWTAERYLASEHIAPTPLHPGARGVIDEHLDALGLARDIVVRSPYF
GLGPQMVAHSRLVLTTGRLFCSRYVGQLPGLRIVRCPVPFPALVYYQLWHELSHQSAAGRWLRGVMRDVARGLPKPGAAA
PRAGAH
>Mature_325_residues
SQPTLFDKIELHLVRVLHTVITERSVSRAALRLRTTQPAVSAQLKRLRALVGDPLLVRSGTGMAPTAVALQLLEPAAELL
RNAERLFGSRAEALAFDPAHSETTFRVAASDYLDPQFLPALVTRLRAEAPGIRVEVLPLSAEFDYRKGLARGEVDLVIGN
WLRPPAELHLGRLLSDEIVCLVAEDHPAVKSPRSWTAERYLASEHIAPTPLHPGARGVIDEHLDALGLARDIVVRSPYFG
LGPQMVAHSRLVLTTGRLFCSRYVGQLPGLRIVRCPVPFPALVYYQLWHELSHQSAAGRWLRGVMRDVARGLPKPGAAAP
RAGAH

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790147, Length=310, Percent_Identity=27.4193548387097, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI87081684, Length=195, Percent_Identity=31.7948717948718, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87081766, Length=184, Percent_Identity=25.5434782608696, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35766; Mature: 35635

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPTLFDKIELHLVRVLHTVITERSVSRAALRLRTTQPAVSAQLKRLRALVGDPLLVRS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEC
GTGMAPTAVALQLLEPAAELLRNAERLFGSRAEALAFDPAHSETTFRVAASDYLDPQFLP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCCEEEEEHHHCCCHHHHH
ALVTRLRAEAPGIRVEVLPLSAEFDYRKGLARGEVDLVIGNWLRPPAELHLGRLLSDEIV
HHHHHHHHCCCCCEEEEEEECCCCHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEE
CLVAEDHPAVKSPRSWTAERYLASEHIAPTPLHPGARGVIDEHLDALGLARDIVVRSPYF
EEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
GLGPQMVAHSRLVLTTGRLFCSRYVGQLPGLRIVRCPVPFPALVYYQLWHELSHQSAAGR
CCCHHHHHCCHHEEHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHH
WLRGVMRDVARGLPKPGAAAPRAGAH
HHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SQPTLFDKIELHLVRVLHTVITERSVSRAALRLRTTQPAVSAQLKRLRALVGDPLLVRS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEC
GTGMAPTAVALQLLEPAAELLRNAERLFGSRAEALAFDPAHSETTFRVAASDYLDPQFLP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCCEEEEEHHHCCCHHHHH
ALVTRLRAEAPGIRVEVLPLSAEFDYRKGLARGEVDLVIGNWLRPPAELHLGRLLSDEIV
HHHHHHHHCCCCCEEEEEEECCCCHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEE
CLVAEDHPAVKSPRSWTAERYLASEHIAPTPLHPGARGVIDEHLDALGLARDIVVRSPYF
EEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
GLGPQMVAHSRLVLTTGRLFCSRYVGQLPGLRIVRCPVPFPALVYYQLWHELSHQSAAGR
CCCHHHHHCCHHEEHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHH
WLRGVMRDVARGLPKPGAAAPRAGAH
HHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]