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The map label for this gene is acoR [H]

Identifier: 124265589

GI number: 124265589

Start: 429555

End: 431549

Strand: Reverse

Name: acoR [H]

Synonym: Mpe_A0396

Alternate gene names: 124265589

Gene position: 431549-429555 (Counterclockwise)

Preceding gene: 124265599

Following gene: 124265583

Centisome position: 10.67

GC content: 70.13

Gene sequence:

>1995_bases
ATGAAGCCGAACGCCAGCCCCTACCTCGGCTTCGACAAGGACGCCCGCGGGGTCAAGAGCCTGTGGGAGCGCTTCAACGC
CGGGCTGATCGACACCGAGGAGCGCCGCGACACCTACCAGCAGCTCCTGCTGCACGAATGGCAGCGCTGCAAGGCGCTGG
GCGTCGATGTCGCCATGACCATGGGCCGCCGCCTGAGCGACAGCGAATTCCGCCTGCGCATGCAGGCGGAACAGCTGCTG
CTCGAAACCGCGGTGCCGATCGTGAGGGACGTCGACCGCTTCCTCGCCGACGTGCCGGGGATCATGATCCTGATCGACCG
CTCCGGCTGCGCGCTGCACATCAGCGGCGACCCGCGTGTCGGCGAGTTCGCAGCCAGCCGCACCGGCATCGTCGTGGGCT
CGCAATGGGACGAGGCCACGGCAGGCACCAACGGCATCGGCACGGCACTCGCGAAGCGGCAGCCGGTGCACGTGTTCGCC
TCCGAGCACTTCTGCGAGGGCTGGCAGTCGTGGTCGTGCTGCGCCGCGCCCATCTTCGACGCCGACGGCCACACCGTGCT
CGGCGTCATCGACTACACGACCATGGCGTCGGATTTCCGCGAACAGGCGCTCGCACTCACGGTCTCGGTCGCGAACTCCA
TCCAGGCGCGCATGACCATGCACCGCGAGCTCGAGCGCAGCCGCCTGGTCACCGCCTTCAGCGAGGCGGCTCGCCGTTAC
CCCTTCGACGACATGCTGGCGCTGGACCATGCCGGGCGCCTGGCCATCCACACGCCCAGCGACCGCTGCCGGCGCATCGC
CGAGAACTGGGCCTCGGGCGGCTTCGAGGGCACCCCCGCCGTGCGCGAAACCTTCGAGGTGACGGCTCCCAACTCCGAAT
CGCGCATCGGCACCCTCATCCTGCTGGCCAAGCCCGCCAGCTACGACCGCGTGTTCCTGCCGTCGAACACGCCGTCCTCG
TTGCGCGACGCGGTGGAGCCGGTCAAGCGCTTCGGCCACTTCCTCACCCGCGACCCGGACACCCGGCGCATGCTGGCCGA
GCTGGAGCGCGTGGCGGCGGCCGACGTGAACGTGCTGATCATCGGCGAGACCGGCACCGGCAAGGAGCTGCTCGCGCGCC
AGTTGCACGCCAGCAGCCCGCGCCGCGCCGAGCCCTACATCGCGGTGAACTGCGGCGCGATCAGCGAAGACCTGATGGAG
AGCACCTTCTTCGGCTACGTGAGGGGCGCGTTCTCCGGCGCCGACCCGCGCGGCCGGGCCGGCTACTTCGAGTCCGCCAA
GGGCGGCACGCTGTTCCTCGACGAAGTGGGCGAGCTGCCGCTGGCCATGCAGGCCGCGATGCTGCGCGTGCTCGAGGACG
GCAGCTACCAGCGCGTGGGCTCCTGCGAAACCCAGCAGGCGCGCTGCCGCATCATCGCCGCGACGCACCGCAACCTGGAG
CAGCTGGTCGCGCAGGGCCGGTTCCGCCAAGACCTGTACTTCCGACTGAAGATCGTCCAGAAGTCCATCAAGCCGCTGCG
CGAGCGGCCCTGCGACCTGACGCTGCTGATCGACCAGTTCGGCGACGCCATGCGCCAGAAGCACGGCCTGCCCACGGTGC
AGCTCCCGCCGGACACCCGCGCCGCGCTCGAACGCTACCGCTGGCCGGGCAATGCGCGCGAGGTGCGCAACGTGATCGAG
GCCGCCGTGCTGTGCGCCGATGGCGCGATCGGCCTCGAATGCCTGCCGCCCGAAGTGACCCGTCCACCCGAGACCAGCAC
CGAACCGGTGGTGGCCGGCACGGCCGGCGAAGGTCTGGCCGCCGTGCGCGACTACGAGCGCCAGCTGATCCTGGGCCTGC
TGCGCAAGTACCGCAAGGTCAACCACGTGGCCAGCGCGCTGGGCATTGCGCGCTCCACGCTGTACCGCAAGTTCGCGGAA
CTCGCCATCGACCAGAGCGAGTTCACCCAGGCGGGCCACGACGAGCGGCCGATCGCGCGCGACGGCATCCACTGA

Upstream 100 bases:

>100_bases
GGTTTGATCTGCTTGAGAAGAAGCCGGCCAACCGGTGTAATCGGCAGACCTTTCCTCACTCACCACCGCACGGGATTCAC
GCGATGAGCGCAGGTCTGTC

Downstream 100 bases:

>100_bases
ACGGTGGCCGCCGCGCGGCCACCGCCCCCTGCCTCACCGCCCGAGCAACTCCCGGATCGCCTGCAAGGCCGTGGGGTCCT
CGATGGTGGTCAGGTCGCCC

Product: sigma-54 dependent transcriptional activator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 664; Mature: 664

Protein sequence:

>664_residues
MKPNASPYLGFDKDARGVKSLWERFNAGLIDTEERRDTYQQLLLHEWQRCKALGVDVAMTMGRRLSDSEFRLRMQAEQLL
LETAVPIVRDVDRFLADVPGIMILIDRSGCALHISGDPRVGEFAASRTGIVVGSQWDEATAGTNGIGTALAKRQPVHVFA
SEHFCEGWQSWSCCAAPIFDADGHTVLGVIDYTTMASDFREQALALTVSVANSIQARMTMHRELERSRLVTAFSEAARRY
PFDDMLALDHAGRLAIHTPSDRCRRIAENWASGGFEGTPAVRETFEVTAPNSESRIGTLILLAKPASYDRVFLPSNTPSS
LRDAVEPVKRFGHFLTRDPDTRRMLAELERVAAADVNVLIIGETGTGKELLARQLHASSPRRAEPYIAVNCGAISEDLME
STFFGYVRGAFSGADPRGRAGYFESAKGGTLFLDEVGELPLAMQAAMLRVLEDGSYQRVGSCETQQARCRIIAATHRNLE
QLVAQGRFRQDLYFRLKIVQKSIKPLRERPCDLTLLIDQFGDAMRQKHGLPTVQLPPDTRAALERYRWPGNAREVRNVIE
AAVLCADGAIGLECLPPEVTRPPETSTEPVVAGTAGEGLAAVRDYERQLILGLLRKYRKVNHVASALGIARSTLYRKFAE
LAIDQSEFTQAGHDERPIARDGIH

Sequences:

>Translated_664_residues
MKPNASPYLGFDKDARGVKSLWERFNAGLIDTEERRDTYQQLLLHEWQRCKALGVDVAMTMGRRLSDSEFRLRMQAEQLL
LETAVPIVRDVDRFLADVPGIMILIDRSGCALHISGDPRVGEFAASRTGIVVGSQWDEATAGTNGIGTALAKRQPVHVFA
SEHFCEGWQSWSCCAAPIFDADGHTVLGVIDYTTMASDFREQALALTVSVANSIQARMTMHRELERSRLVTAFSEAARRY
PFDDMLALDHAGRLAIHTPSDRCRRIAENWASGGFEGTPAVRETFEVTAPNSESRIGTLILLAKPASYDRVFLPSNTPSS
LRDAVEPVKRFGHFLTRDPDTRRMLAELERVAAADVNVLIIGETGTGKELLARQLHASSPRRAEPYIAVNCGAISEDLME
STFFGYVRGAFSGADPRGRAGYFESAKGGTLFLDEVGELPLAMQAAMLRVLEDGSYQRVGSCETQQARCRIIAATHRNLE
QLVAQGRFRQDLYFRLKIVQKSIKPLRERPCDLTLLIDQFGDAMRQKHGLPTVQLPPDTRAALERYRWPGNAREVRNVIE
AAVLCADGAIGLECLPPEVTRPPETSTEPVVAGTAGEGLAAVRDYERQLILGLLRKYRKVNHVASALGIARSTLYRKFAE
LAIDQSEFTQAGHDERPIARDGIH
>Mature_664_residues
MKPNASPYLGFDKDARGVKSLWERFNAGLIDTEERRDTYQQLLLHEWQRCKALGVDVAMTMGRRLSDSEFRLRMQAEQLL
LETAVPIVRDVDRFLADVPGIMILIDRSGCALHISGDPRVGEFAASRTGIVVGSQWDEATAGTNGIGTALAKRQPVHVFA
SEHFCEGWQSWSCCAAPIFDADGHTVLGVIDYTTMASDFREQALALTVSVANSIQARMTMHRELERSRLVTAFSEAARRY
PFDDMLALDHAGRLAIHTPSDRCRRIAENWASGGFEGTPAVRETFEVTAPNSESRIGTLILLAKPASYDRVFLPSNTPSS
LRDAVEPVKRFGHFLTRDPDTRRMLAELERVAAADVNVLIIGETGTGKELLARQLHASSPRRAEPYIAVNCGAISEDLME
STFFGYVRGAFSGADPRGRAGYFESAKGGTLFLDEVGELPLAMQAAMLRVLEDGSYQRVGSCETQQARCRIIAATHRNLE
QLVAQGRFRQDLYFRLKIVQKSIKPLRERPCDLTLLIDQFGDAMRQKHGLPTVQLPPDTRAALERYRWPGNAREVRNVIE
AAVLCADGAIGLECLPPEVTRPPETSTEPVVAGTAGEGLAAVRDYERQLILGLLRKYRKVNHVASALGIARSTLYRKFAE
LAIDQSEFTQAGHDERPIARDGIH

Specific function: Acts as a transcriptional activator of the acoABCL operon encoding the acetoin dehydrogenase complex [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=333, Percent_Identity=38.1381381381381, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1789233, Length=307, Percent_Identity=38.4364820846906, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI1789087, Length=320, Percent_Identity=40.9375, Blast_Score=225, Evalue=6e-60,
Organism=Escherichia coli, GI87082152, Length=281, Percent_Identity=44.8398576512456, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1787583, Length=326, Percent_Identity=34.9693251533742, Blast_Score=212, Evalue=7e-56,
Organism=Escherichia coli, GI1790437, Length=353, Percent_Identity=37.1104815864023, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI87082117, Length=313, Percent_Identity=38.6581469648562, Blast_Score=208, Evalue=1e-54,
Organism=Escherichia coli, GI1790299, Length=325, Percent_Identity=40, Blast_Score=208, Evalue=1e-54,
Organism=Escherichia coli, GI1788905, Length=389, Percent_Identity=34.4473007712082, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1786524, Length=263, Percent_Identity=41.8250950570342, Blast_Score=196, Evalue=6e-51,
Organism=Escherichia coli, GI87081872, Length=245, Percent_Identity=41.6326530612245, Blast_Score=180, Evalue=3e-46,
Organism=Escherichia coli, GI87081858, Length=674, Percent_Identity=26.1127596439169, Blast_Score=179, Evalue=6e-46,
Organism=Escherichia coli, GI1789828, Length=257, Percent_Identity=34.6303501945525, Blast_Score=134, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 73520; Mature: 73520

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPNASPYLGFDKDARGVKSLWERFNAGLIDTEERRDTYQQLLLHEWQRCKALGVDVAMT
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
MGRRLSDSEFRLRMQAEQLLLETAVPIVRDVDRFLADVPGIMILIDRSGCALHISGDPRV
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCH
GEFAASRTGIVVGSQWDEATAGTNGIGTALAKRQPVHVFASEHFCEGWQSWSCCAAPIFD
HHHHCCCCCEEEECCCCCCCCCCCCHHHHHHCCCCEEEECCHHHHCCCCCCCEEECCEEC
ADGHTVLGVIDYTTMASDFREQALALTVSVANSIQARMTMHRELERSRLVTAFSEAARRY
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PFDDMLALDHAGRLAIHTPSDRCRRIAENWASGGFEGTPAVRETFEVTAPNSESRIGTLI
CCHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCCCHHHHCEEEECCCCCCCCEEEE
LLAKPASYDRVFLPSNTPSSLRDAVEPVKRFGHFLTRDPDTRRMLAELERVAAADVNVLI
EEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEE
IGETGTGKELLARQLHASSPRRAEPYIAVNCGAISEDLMESTFFGYVRGAFSGADPRGRA
EECCCCCHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
GYFESAKGGTLFLDEVGELPLAMQAAMLRVLEDGSYQRVGSCETQQARCRIIAATHRNLE
CCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEHHHHHHHH
QLVAQGRFRQDLYFRLKIVQKSIKPLRERPCDLTLLIDQFGDAMRQKHGLPTVQLPPDTR
HHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCEEECCCCHH
AALERYRWPGNAREVRNVIEAAVLCADGAIGLECLPPEVTRPPETSTEPVVAGTAGEGLA
HHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCEEEECCCCCHH
AVRDYERQLILGLLRKYRKVNHVASALGIARSTLYRKFAELAIDQSEFTQAGHDERPIAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCC
DGIH
CCCC
>Mature Secondary Structure
MKPNASPYLGFDKDARGVKSLWERFNAGLIDTEERRDTYQQLLLHEWQRCKALGVDVAMT
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
MGRRLSDSEFRLRMQAEQLLLETAVPIVRDVDRFLADVPGIMILIDRSGCALHISGDPRV
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCH
GEFAASRTGIVVGSQWDEATAGTNGIGTALAKRQPVHVFASEHFCEGWQSWSCCAAPIFD
HHHHCCCCCEEEECCCCCCCCCCCCHHHHHHCCCCEEEECCHHHHCCCCCCCEEECCEEC
ADGHTVLGVIDYTTMASDFREQALALTVSVANSIQARMTMHRELERSRLVTAFSEAARRY
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PFDDMLALDHAGRLAIHTPSDRCRRIAENWASGGFEGTPAVRETFEVTAPNSESRIGTLI
CCHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCCCHHHHCEEEECCCCCCCCEEEE
LLAKPASYDRVFLPSNTPSSLRDAVEPVKRFGHFLTRDPDTRRMLAELERVAAADVNVLI
EEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEE
IGETGTGKELLARQLHASSPRRAEPYIAVNCGAISEDLMESTFFGYVRGAFSGADPRGRA
EECCCCCHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
GYFESAKGGTLFLDEVGELPLAMQAAMLRVLEDGSYQRVGSCETQQARCRIIAATHRNLE
CCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEHHHHHHHH
QLVAQGRFRQDLYFRLKIVQKSIKPLRERPCDLTLLIDQFGDAMRQKHGLPTVQLPPDTR
HHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCEEECCCCHH
AALERYRWPGNAREVRNVIEAAVLCADGAIGLECLPPEVTRPPETSTEPVVAGTAGEGLA
HHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCEEEECCCCCHH
AVRDYERQLILGLLRKYRKVNHVASALGIARSTLYRKFAELAIDQSEFTQAGHDERPIAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCC
DGIH
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377; 10368162 [H]