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The map label for this gene is qseC [H]

Identifier: 124265270

GI number: 124265270

Start: 71330

End: 72859

Strand: Direct

Name: qseC [H]

Synonym: Mpe_A0077

Alternate gene names: 124265270

Gene position: 71330-72859 (Clockwise)

Preceding gene: 124265269

Following gene: 124265271

Centisome position: 1.76

GC content: 71.37

Gene sequence:

>1530_bases
ATGAACACGCTGCGCGGACAACGCTCGCTGTTCGGCGAGATCCTCGACTGGATGCTCGCGCCGCTGCTGTTGCTGTGGCC
GATGAGTGTCGCGCTGACCTGGCTGGTCGCCCAGAACATCGCCAACCGTCCCTACGATCGCGCGCTCGGCGAGATGGCGA
GGGCGCTGTCGCAGCAGGTAAGCGTCGACCAGGGCCGCGTTGCGTTCGCTCTGCCGCCCGGAGCCGATCAACTGCTGCGG
GCCGACGAGGCGGACCAGATCTACTTCCAGGTGCTGGGCGCGCGGGGCGAGTATGTGGGTGGCGATCACACGCTGCCGGT
CCCGCGCGAGGACGACGTGGCGGCGGTCGGAGAGGTCCGCTATCGCGACGACGAGGTGCACAACGAGGCCGTGCGCGTGG
CCTACCTGTGGGTGGCGATGCCCGCCGCGCCGCGGATTCCCGGCGCCACCTCGCCGGCGCTGGTGCAGGTGGCCGAAACC
CTGGGCAAGCGCTCGCAGCTGGCCACCGAGATCATCAAGGGCGTGATCCTGCCGCAGTTCGTGATCCTGCCGCTCGCGGT
GCTGCTGGTGTGGCTGGCACTGGCGCGCGGCATCGCGCCGCTCAACGAGCTGCAGCAGCGCATCCGCCGCCGTGCGGCTG
ATGACCTGAGCCCGATCGACGAGATGGAGGCGCCGGAGGAGGTGTCGCCGCTGGTGCGAGCCATCAACGACCTGCTGGAG
CGCCTGGACCGCTCGCTGGCGACGCAGCGGCGCTTTCTCGCCGATGCCGCCCACCAGCTCAAGACGCCGCTGGCCGGCCT
GCGCACCCAGGCCGAGATCGCGCAGCGCGAGATCGACGCGGGTGAACGCGAGCCCGAGGCGCTGAAGCGCTCGCTGCAGC
AGATCGCGCTGTCGAGCCAGCGGGCCGCGCACATGGTCAACCAGTTGCTGGCGATGGCGCGCGCCGAGGACCGCGAACTC
GCCGCCCGCGTGGCCGAGGTCCGGCTGGCGAGGCTGGCAACGGAGACCGTCCGCGACTTCGTGCCGCGCGCGCTCGAGAA
GCGCATCGACCTCGGCTACGAGGGACCGGGCGCCGACGGCGAGACGGCCGAGCCGCAGCGCAGCAGCGTGCTCGGCCATG
CGCTGCTGCTGCGCGAGATGATCCGCAACCTGGTCGACAACGCCCTGCACTACACCCCTCCCGGAGGCACGGTGACGGTG
AGGGTCGTCAGCGACCCGTTCGGCCAGGTCGTGGTGCTGCAGGTCGAGGATTCCGGCCCCGGCATCCCCGCGGCGGAGCG
TGAACTGGTGTTCCAGCCCTTCTACCGCGCCCTGGGGACCGATGTCGATGGCTCGGGCCTGGGCCTGGCGATCGTCGCCG
AGATCGCTCGACAGCACGGTGCTACGTTGACGCTGGACGACACCCGCGAAGGCCCCGTGCCTGAAGGCAGCAGCCCCGGC
GCGCGCTTCACCGTGCGCTTCGCCGCCTGGCCGGCCGACCGTCTGCCGCGTGCCGCGCCTCTTGCCAGCGGGACGGCCAA
CCCGGCTTAG

Upstream 100 bases:

>100_bases
AGCAGGGCCCGGTGCGCATCGCCACCGTGCGCGGCCTGGGCTACTGCCTCGAGAAGATCGCGGGCTGAGCCGGCATGCTG
CGCGGCGCGCGCCTTCGGGC

Downstream 100 bases:

>100_bases
TCCCGGCCGACGCCAAGGAGGGTTGTTTGCTGCAATGCAGCATTCGTCGGGGCGCCGGCGTAGACTGGACGCCAGCCGGG
AGATGCCATGCCAGAGTCGC

Product: putative transmembrane sensor histidine kinase transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MNTLRGQRSLFGEILDWMLAPLLLLWPMSVALTWLVAQNIANRPYDRALGEMARALSQQVSVDQGRVAFALPPGADQLLR
ADEADQIYFQVLGARGEYVGGDHTLPVPREDDVAAVGEVRYRDDEVHNEAVRVAYLWVAMPAAPRIPGATSPALVQVAET
LGKRSQLATEIIKGVILPQFVILPLAVLLVWLALARGIAPLNELQQRIRRRAADDLSPIDEMEAPEEVSPLVRAINDLLE
RLDRSLATQRRFLADAAHQLKTPLAGLRTQAEIAQREIDAGEREPEALKRSLQQIALSSQRAAHMVNQLLAMARAEDREL
AARVAEVRLARLATETVRDFVPRALEKRIDLGYEGPGADGETAEPQRSSVLGHALLLREMIRNLVDNALHYTPPGGTVTV
RVVSDPFGQVVVLQVEDSGPGIPAAERELVFQPFYRALGTDVDGSGLGLAIVAEIARQHGATLTLDDTREGPVPEGSSPG
ARFTVRFAAWPADRLPRAAPLASGTANPA

Sequences:

>Translated_509_residues
MNTLRGQRSLFGEILDWMLAPLLLLWPMSVALTWLVAQNIANRPYDRALGEMARALSQQVSVDQGRVAFALPPGADQLLR
ADEADQIYFQVLGARGEYVGGDHTLPVPREDDVAAVGEVRYRDDEVHNEAVRVAYLWVAMPAAPRIPGATSPALVQVAET
LGKRSQLATEIIKGVILPQFVILPLAVLLVWLALARGIAPLNELQQRIRRRAADDLSPIDEMEAPEEVSPLVRAINDLLE
RLDRSLATQRRFLADAAHQLKTPLAGLRTQAEIAQREIDAGEREPEALKRSLQQIALSSQRAAHMVNQLLAMARAEDREL
AARVAEVRLARLATETVRDFVPRALEKRIDLGYEGPGADGETAEPQRSSVLGHALLLREMIRNLVDNALHYTPPGGTVTV
RVVSDPFGQVVVLQVEDSGPGIPAAERELVFQPFYRALGTDVDGSGLGLAIVAEIARQHGATLTLDDTREGPVPEGSSPG
ARFTVRFAAWPADRLPRAAPLASGTANPA
>Mature_509_residues
MNTLRGQRSLFGEILDWMLAPLLLLWPMSVALTWLVAQNIANRPYDRALGEMARALSQQVSVDQGRVAFALPPGADQLLR
ADEADQIYFQVLGARGEYVGGDHTLPVPREDDVAAVGEVRYRDDEVHNEAVRVAYLWVAMPAAPRIPGATSPALVQVAET
LGKRSQLATEIIKGVILPQFVILPLAVLLVWLALARGIAPLNELQQRIRRRAADDLSPIDEMEAPEEVSPLVRAINDLLE
RLDRSLATQRRFLADAAHQLKTPLAGLRTQAEIAQREIDAGEREPEALKRSLQQIALSSQRAAHMVNQLLAMARAEDREL
AARVAEVRLARLATETVRDFVPRALEKRIDLGYEGPGADGETAEPQRSSVLGHALLLREMIRNLVDNALHYTPPGGTVTV
RVVSDPFGQVVVLQVEDSGPGIPAAERELVFQPFYRALGTDVDGSGLGLAIVAEIARQHGATLTLDDTREGPVPEGSSPG
ARFTVRFAAWPADRLPRAAPLASGTANPA

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=451, Percent_Identity=28.6031042128603, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1786783, Length=374, Percent_Identity=29.4117647058824, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI1790551, Length=304, Percent_Identity=32.5657894736842, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1790861, Length=314, Percent_Identity=30.8917197452229, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1790346, Length=253, Percent_Identity=29.6442687747036, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1788393, Length=273, Percent_Identity=27.1062271062271, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87082128, Length=296, Percent_Identity=28.7162162162162, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787374, Length=406, Percent_Identity=27.0935960591133, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786600, Length=235, Percent_Identity=29.7872340425532, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1787894, Length=265, Percent_Identity=28.3018867924528, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI145693157, Length=252, Percent_Identity=26.1904761904762, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1788279, Length=318, Percent_Identity=22.6415094339623, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI48994928, Length=261, Percent_Identity=26.8199233716475, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786912, Length=222, Percent_Identity=30.1801801801802, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1789149, Length=310, Percent_Identity=24.1935483870968, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=27.7777777777778, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55399; Mature: 55399

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLRGQRSLFGEILDWMLAPLLLLWPMSVALTWLVAQNIANRPYDRALGEMARALSQQV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
SVDQGRVAFALPPGADQLLRADEADQIYFQVLGARGEYVGGDHTLPVPREDDVAAVGEVR
CCCCCCEEEECCCCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHH
YRDDEVHNEAVRVAYLWVAMPAAPRIPGATSPALVQVAETLGKRSQLATEIIKGVILPQF
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VILPLAVLLVWLALARGIAPLNELQQRIRRRAADDLSPIDEMEAPEEVSPLVRAINDLLE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHH
RLDRSLATQRRFLADAAHQLKTPLAGLRTQAEIAQREIDAGEREPEALKRSLQQIALSSQ
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
RAAHMVNQLLAMARAEDRELAARVAEVRLARLATETVRDFVPRALEKRIDLGYEGPGADG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ETAEPQRSSVLGHALLLREMIRNLVDNALHYTPPGGTVTVRVVSDPFGQVVVLQVEDSGP
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCEEEEEEECCCCCCEEEEEEECCCC
GIPAAERELVFQPFYRALGTDVDGSGLGLAIVAEIARQHGATLTLDDTREGPVPEGSSPG
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCC
ARFTVRFAAWPADRLPRAAPLASGTANPA
CEEEEEEECCCHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNTLRGQRSLFGEILDWMLAPLLLLWPMSVALTWLVAQNIANRPYDRALGEMARALSQQV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
SVDQGRVAFALPPGADQLLRADEADQIYFQVLGARGEYVGGDHTLPVPREDDVAAVGEVR
CCCCCCEEEECCCCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHH
YRDDEVHNEAVRVAYLWVAMPAAPRIPGATSPALVQVAETLGKRSQLATEIIKGVILPQF
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VILPLAVLLVWLALARGIAPLNELQQRIRRRAADDLSPIDEMEAPEEVSPLVRAINDLLE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHH
RLDRSLATQRRFLADAAHQLKTPLAGLRTQAEIAQREIDAGEREPEALKRSLQQIALSSQ
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
RAAHMVNQLLAMARAEDRELAARVAEVRLARLATETVRDFVPRALEKRIDLGYEGPGADG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ETAEPQRSSVLGHALLLREMIRNLVDNALHYTPPGGTVTVRVVSDPFGQVVVLQVEDSGP
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCEEEEEEECCCCCCEEEEEEECCCC
GIPAAERELVFQPFYRALGTDVDGSGLGLAIVAEIARQHGATLTLDDTREGPVPEGSSPG
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCC
ARFTVRFAAWPADRLPRAAPLASGTANPA
CEEEEEEECCCHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]