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The map label for this gene is folP [H]

Identifier: 124023097

GI number: 124023097

Start: 1188260

End: 1188493

Strand: Direct

Name: folP [H]

Synonym: P9303_13921

Alternate gene names: 124023097

Gene position: 1188260-1188493 (Clockwise)

Preceding gene: 124023096

Following gene: 124023099

Centisome position: 44.29

GC content: 52.56

Gene sequence:

>234_bases
TTGATTTTGTTGAAGCATCTAGAGAGGATTTGCTCTGAAGGCTTCCCTGTTTTGGTTGGGCCCTCAAGGAAACGCTTCAT
CGGAGATGTTTTGAACCAACCGGACCCAGATGCTCGTCTATGGGGTACTGCTGCCGTGGCCTGCCGTTGTCTGCAGGCGA
AGGCGGCAATGGTGAGAGTGCATGATGTGGGCCCAATCCATCAGACCCTTCAAATGGCTAGCAGACTGTGGTAA

Upstream 100 bases:

>100_bases
TACTTCGTCGAACGGATCAGGTTTTGGCAGCTGGTATTCGATCTGAACAGTTGATTTGGGACCCAGGCTTGGGTTTTGCT
AAAACCACTGAACAACAAAT

Downstream 100 bases:

>100_bases
TAGGGGCTTTAGTTACTTTTTAATCATTCGCCAGATGATTGGTTGTCTGGAGTTGTTACTCCTTCAATTCGATCTTCTAT
TTCCTGGTAAAGCTCTTGCA

Product: hypothetical protein

Products: NA

Alternate protein names: DHPS; Dihydropteroate pyrophosphorylase [H]

Number of amino acids: Translated: 77; Mature: 77

Protein sequence:

>77_residues
MILLKHLERICSEGFPVLVGPSRKRFIGDVLNQPDPDARLWGTAAVACRCLQAKAAMVRVHDVGPIHQTLQMASRLW

Sequences:

>Translated_77_residues
MILLKHLERICSEGFPVLVGPSRKRFIGDVLNQPDPDARLWGTAAVACRCLQAKAAMVRVHDVGPIHQTLQMASRLW
>Mature_77_residues
MILLKHLERICSEGFPVLVGPSRKRFIGDVLNQPDPDARLWGTAAVACRCLQAKAAMVRVHDVGPIHQTLQMASRLW

Specific function: DHPS catalyzes the formation of the immediate precursor of folic acid. It is implicated in resistance to sulfonamide [H]

COG id: COG0294

COG function: function code H; Dihydropteroate synthase and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006390
- InterPro:   IPR011005
- InterPro:   IPR000489 [H]

Pfam domain/function: PF00809 Pterin_bind [H]

EC number: =2.5.1.15 [H]

Molecular weight: Translated: 8590; Mature: 8590

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS50972 PTERIN_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLKHLERICSEGFPVLVGPSRKRFIGDVLNQPDPDARLWGTAAVACRCLQAKAAMVRV
CHHHHHHHHHHHCCCCEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
HDVGPIHQTLQMASRLW
CCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MILLKHLERICSEGFPVLVGPSRKRFIGDVLNQPDPDARLWGTAAVACRCLQAKAAMVRV
CHHHHHHHHHHHCCCCEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
HDVGPIHQTLQMASRLW
CCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]