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The map label for this gene is dapB [H]

Identifier: 124023099

GI number: 124023099

Start: 1192676

End: 1193527

Strand: Direct

Name: dapB [H]

Synonym: P9303_13941

Alternate gene names: 124023099

Gene position: 1192676-1193527 (Clockwise)

Preceding gene: 124023097

Following gene: 124023100

Centisome position: 44.46

GC content: 52.46

Gene sequence:

>852_bases
ATGACCTCAGTCCCTCCAGAGTTGATTCCTGTTGTGGTTGCTGGCGCACTGGGCCGCATGGGGGCTGAGGTCATCAAAGC
CGTTCATCTCGCTTCGGATTGTGAGTTGGTAGGTGCAGTGGACACAACGCCAGGCAAGGAAGGCGTGGAGGTTGGGGAGG
AGCTTGGAATAGGTGTTCTTGATGTTGCTTTGACGTCCGACATTGAGGCTTGTCTTTGTTCTGTCAGCCAGTCTTTTCAT
CGGACAGGTCCTGGACAAGGTGCTGTGCTTGTTGATTTCACTCATCCTTCAGTGGTTTACGAGCACACCAGGGCGGCGTT
TGCCTATGGGGTTCATCCGGTCATAGGCACTACAGGTCTGTCTCCAGATCAGTTGCTTGATCTCAGCAACTTTGCTGAAA
AGGCCTCGATGGGGGGAGCTGTTATCCCAAATTTCTCTGTTGGCATGGTCTTACTGCAACAGGCAGCAGCCGCGGCTGCG
AGCTTCTATCAACATGCAGAACTGACTGAGCTGCATCACAACCGTAAGGCTGATGCCCCGAGTGGCACATGTATAAAAAC
TGCAGAGATGATGGAGGAGCTCGGTAAAAGTTTTAATTCGCCTGAAGTTGATGAGCATGAATCGCTGACTGGTTCCCGTG
GTGGCTTACGAGCTAGTGGCTTAAGACTCCATTCGCTTCGTCTGCCTGGATTGGTTGCCCATCAGGAAGTGATGTTCGGA
GCTCCTGGAGAGAGCTATACACTCCGACACGACACCATTGATCGTTCGGCCTACATGCCAGGTGTGTTGCTAACCGTTCG
TAAGGTGCGACAGCTTCAAGGTCTGGTTTATGGCCTTGAACGCCTCATCTGA

Upstream 100 bases:

>100_bases
TAATTTGATGAAGCCTAGGTTGTCTGGGGCTCAGCGTGAAGTTCGCTGCCTGGGTGTTACATGAGTCGACCCATAGGCTT
TATTCAGCGATCGCCCTCCC

Downstream 100 bases:

>100_bases
AATTCATTTGCGTGTCGATGTTGGTCCCTTTGCGTCCAGGAGAGCTTCAGAGGCTTATCCCTGCAGTGGCCACCAGTAAT
CAATTCGCAGCGGCCCTTGG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MTSVPPELIPVVVAGALGRMGAEVIKAVHLASDCELVGAVDTTPGKEGVEVGEELGIGVLDVALTSDIEACLCSVSQSFH
RTGPGQGAVLVDFTHPSVVYEHTRAAFAYGVHPVIGTTGLSPDQLLDLSNFAEKASMGGAVIPNFSVGMVLLQQAAAAAA
SFYQHAELTELHHNRKADAPSGTCIKTAEMMEELGKSFNSPEVDEHESLTGSRGGLRASGLRLHSLRLPGLVAHQEVMFG
APGESYTLRHDTIDRSAYMPGVLLTVRKVRQLQGLVYGLERLI

Sequences:

>Translated_283_residues
MTSVPPELIPVVVAGALGRMGAEVIKAVHLASDCELVGAVDTTPGKEGVEVGEELGIGVLDVALTSDIEACLCSVSQSFH
RTGPGQGAVLVDFTHPSVVYEHTRAAFAYGVHPVIGTTGLSPDQLLDLSNFAEKASMGGAVIPNFSVGMVLLQQAAAAAA
SFYQHAELTELHHNRKADAPSGTCIKTAEMMEELGKSFNSPEVDEHESLTGSRGGLRASGLRLHSLRLPGLVAHQEVMFG
APGESYTLRHDTIDRSAYMPGVLLTVRKVRQLQGLVYGLERLI
>Mature_282_residues
TSVPPELIPVVVAGALGRMGAEVIKAVHLASDCELVGAVDTTPGKEGVEVGEELGIGVLDVALTSDIEACLCSVSQSFHR
TGPGQGAVLVDFTHPSVVYEHTRAAFAYGVHPVIGTTGLSPDQLLDLSNFAEKASMGGAVIPNFSVGMVLLQQAAAAAAS
FYQHAELTELHHNRKADAPSGTCIKTAEMMEELGKSFNSPEVDEHESLTGSRGGLRASGLRLHSLRLPGLVAHQEVMFGA
PGESYTLRHDTIDRSAYMPGVLLTVRKVRQLQGLVYGLERLI

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=277, Percent_Identity=30.6859205776173, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 29890; Mature: 29759

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVPPELIPVVVAGALGRMGAEVIKAVHLASDCELVGAVDTTPGKEGVEVGEELGIGVL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHCCCHH
DVALTSDIEACLCSVSQSFHRTGPGQGAVLVDFTHPSVVYEHTRAAFAYGVHPVIGTTGL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHCCCCC
SPDQLLDLSNFAEKASMGGAVIPNFSVGMVLLQQAAAAAASFYQHAELTELHHNRKADAP
CHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SGTCIKTAEMMEELGKSFNSPEVDEHESLTGSRGGLRASGLRLHSLRLPGLVAHQEVMFG
CCCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCEECCEEEEEECCCCHHHHHHHEEC
APGESYTLRHDTIDRSAYMPGVLLTVRKVRQLQGLVYGLERLI
CCCCCEEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TSVPPELIPVVVAGALGRMGAEVIKAVHLASDCELVGAVDTTPGKEGVEVGEELGIGVL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHCCCHH
DVALTSDIEACLCSVSQSFHRTGPGQGAVLVDFTHPSVVYEHTRAAFAYGVHPVIGTTGL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHCCCCC
SPDQLLDLSNFAEKASMGGAVIPNFSVGMVLLQQAAAAAASFYQHAELTELHHNRKADAP
CHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SGTCIKTAEMMEELGKSFNSPEVDEHESLTGSRGGLRASGLRLHSLRLPGLVAHQEVMFG
CCCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCEECCEEEEEECCCCHHHHHHHEEC
APGESYTLRHDTIDRSAYMPGVLLTVRKVRQLQGLVYGLERLI
CCCCCEEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]