Click here to switch to the map view.

The map label for this gene is crtH [H]

Identifier: 124022708

GI number: 124022708

Start: 915200

End: 916762

Strand: Reverse

Name: crtH [H]

Synonym: P9303_10011

Alternate gene names: 124022708

Gene position: 916762-915200 (Counterclockwise)

Preceding gene: 124022709

Following gene: 124022707

Centisome position: 34.17

GC content: 55.09

Gene sequence:

>1563_bases
ATGGAACCTATCCGCATCGAAAAAGACGCAACGCAGCCTTGGGATGCTGTGGTTATCGGTTCGGGCATCGGCGGCCTGGT
CACCGCCAGTCAGCTAGCTGTCAAAGGTGCCAAGGTTCTTGTTCTGGAGAGCTACACAATCCCAGGTGGTAGTAGCGGCT
CATTCCAGCGAGAGGGCTACACCTTTGATGTAGGTGCATCAATGATCTTCGGGTTCGGAGAAAAGGGATACACCAACCTG
CTCACCCGAGCCTTGGCCGATGTGGGTGAGCACTGTGACACCCTGCCTGACCCCGCCCAACTCGCCTACCACCTTCCTGG
AGGATTAGAGCTCGCAGTTGATCGGAAATACGAGCAGTTCATTGCTGATCTCACCGCACGCTTCCCCCACGAAGCGAAGG
GGATCCGTCACTTTTACGACATCTGTTGGCAAGTGTTCAACTGCCTGGATGCAATGCCACTGCTATCGATCGAGGATCCC
ACTTATCTGGCCAAAGTTTTTTTCAAGTCCCCCCTGGCCTGTCTCGGTCTTGCGCGCTGGTTGCCCGTCAACGTGGGTGA
TGTAGCCAGGCGTCACATCAAAGACCCAGAACTGTTGCGGTTCATCGACATTGAATGCTTCTGCTGGTCAGTGATGCCTG
CCGACCTCACACCGATGATCAATGCTGGCATGGTGTTTTCAGATCGCCATGCCGGTGGCATCAACTACCCCAAAGGAGGC
GTTGGTGTGATAGCCCAAAAGCTCGTCAAAGGCATGCAACGTCATGGTGGTGAGATCCGCTACAAGGCACGTGTCACACG
AGTGGTGCTAAAAGATAACCGTGCTGTTGGTGTACAGCTAGCAAATGGAGAAATCATCCACGCCCGCAGGGTGATATCCA
ACGCCACTCGCTGGGACACATTCAGCGGTGAGGGGTCCAAACAGGCCCTGGTGGATGCAGAACACACACCCGCAGCGGAG
CAGACCTGGCGACGCCGCTATGTGCCCTCGCCATCCTTCCTCTCTCTTCACCTTGGGGTCCGTAACGAGGCCATTCCAGC
CAACAGCCACTGCCACCATCTGCTCCTAGAAAGCTGGGATGAAATGGAGAGTGAACAGGGTGTCGCATTCGTCTCGATGC
CGACTCTCCTGGATCCATCCCTGTCGCCAGAGGGGCATCACATCGTCCACGCCTTCACACCATCCTCAATGCAGGCATGG
CAAGACCTAAGCCCTGCGACCTACAACAGCAAAAAGCAAGCTGATGCTGATCGTCTAATCAGGAAACTCGAAAAAATCCT
GCCTGGCTTAAGTCAAGCCATCGTTCACCGAGAGGTGGGCACTCCTCGTAGCCATCGACGTTTCCTAGGACGATTTCAGG
GTAGCTATGGGCCAATCCCCTCAAGTCGTTTACCAGGCCTTCTCACCATGCCCTTTAACCGCACTGGACTCAAAGGGCTT
TATTGCGTCGGCGACTCTTGTTTCCCTGGCCAAGGCCTAAATGCAGTTGCTTTTAGTGGCTTTGCCTGCTCCCATCTCAT
CGGTGCCGATTTAGGGATCAACCCCTGGGCCCTACCTAATTGA

Upstream 100 bases:

>100_bases
CATTAATCTCTCCAGCAAAGCTGCCGCAAACTTCACAGTCAGAGTTGACGGGTTCAGAGTTGCATGCAAGCCCTTAGCGT
CAAGCTGTTGAGACCATGCC

Downstream 100 bases:

>100_bases
TTCATCTTCTAGAGATCTTCATAGAAGACAGTCGTTGCCAGAACGACCTTGAAGTACAAGGCAGCAGCAGAAATTGTTCC
ACGGTATGGCTAGCACATCT

Product: carotenoid isomerase

Products: NA

Alternate protein names: Phytoene desaturase [H]

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MEPIRIEKDATQPWDAVVIGSGIGGLVTASQLAVKGAKVLVLESYTIPGGSSGSFQREGYTFDVGASMIFGFGEKGYTNL
LTRALADVGEHCDTLPDPAQLAYHLPGGLELAVDRKYEQFIADLTARFPHEAKGIRHFYDICWQVFNCLDAMPLLSIEDP
TYLAKVFFKSPLACLGLARWLPVNVGDVARRHIKDPELLRFIDIECFCWSVMPADLTPMINAGMVFSDRHAGGINYPKGG
VGVIAQKLVKGMQRHGGEIRYKARVTRVVLKDNRAVGVQLANGEIIHARRVISNATRWDTFSGEGSKQALVDAEHTPAAE
QTWRRRYVPSPSFLSLHLGVRNEAIPANSHCHHLLLESWDEMESEQGVAFVSMPTLLDPSLSPEGHHIVHAFTPSSMQAW
QDLSPATYNSKKQADADRLIRKLEKILPGLSQAIVHREVGTPRSHRRFLGRFQGSYGPIPSSRLPGLLTMPFNRTGLKGL
YCVGDSCFPGQGLNAVAFSGFACSHLIGADLGINPWALPN

Sequences:

>Translated_520_residues
MEPIRIEKDATQPWDAVVIGSGIGGLVTASQLAVKGAKVLVLESYTIPGGSSGSFQREGYTFDVGASMIFGFGEKGYTNL
LTRALADVGEHCDTLPDPAQLAYHLPGGLELAVDRKYEQFIADLTARFPHEAKGIRHFYDICWQVFNCLDAMPLLSIEDP
TYLAKVFFKSPLACLGLARWLPVNVGDVARRHIKDPELLRFIDIECFCWSVMPADLTPMINAGMVFSDRHAGGINYPKGG
VGVIAQKLVKGMQRHGGEIRYKARVTRVVLKDNRAVGVQLANGEIIHARRVISNATRWDTFSGEGSKQALVDAEHTPAAE
QTWRRRYVPSPSFLSLHLGVRNEAIPANSHCHHLLLESWDEMESEQGVAFVSMPTLLDPSLSPEGHHIVHAFTPSSMQAW
QDLSPATYNSKKQADADRLIRKLEKILPGLSQAIVHREVGTPRSHRRFLGRFQGSYGPIPSSRLPGLLTMPFNRTGLKGL
YCVGDSCFPGQGLNAVAFSGFACSHLIGADLGINPWALPN
>Mature_520_residues
MEPIRIEKDATQPWDAVVIGSGIGGLVTASQLAVKGAKVLVLESYTIPGGSSGSFQREGYTFDVGASMIFGFGEKGYTNL
LTRALADVGEHCDTLPDPAQLAYHLPGGLELAVDRKYEQFIADLTARFPHEAKGIRHFYDICWQVFNCLDAMPLLSIEDP
TYLAKVFFKSPLACLGLARWLPVNVGDVARRHIKDPELLRFIDIECFCWSVMPADLTPMINAGMVFSDRHAGGINYPKGG
VGVIAQKLVKGMQRHGGEIRYKARVTRVVLKDNRAVGVQLANGEIIHARRVISNATRWDTFSGEGSKQALVDAEHTPAAE
QTWRRRYVPSPSFLSLHLGVRNEAIPANSHCHHLLLESWDEMESEQGVAFVSMPTLLDPSLSPEGHHIVHAFTPSSMQAW
QDLSPATYNSKKQADADRLIRKLEKILPGLSQAIVHREVGTPRSHRRFLGRFQGSYGPIPSSRLPGLLTMPFNRTGLKGL
YCVGDSCFPGQGLNAVAFSGFACSHLIGADLGINPWALPN

Specific function: This enzyme converts phytoene into lycopene via the intermediaries of phytofluene, zeta-carotene and neurosporene by the introduction of four double bonds [H]

COG id: COG1233

COG function: function code Q; Phytoene dehydrogenase and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid/retinoid oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI229577391, Length=561, Percent_Identity=24.0641711229947, Blast_Score=81, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR008150
- InterPro:   IPR014105 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: NA

Molecular weight: Translated: 57044; Mature: 57044

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPIRIEKDATQPWDAVVIGSGIGGLVTASQLAVKGAKVLVLESYTIPGGSSGSFQREGY
CCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCE
TFDVGASMIFGFGEKGYTNLLTRALADVGEHCDTLPDPAQLAYHLPGGLELAVDRKYEQF
EEECCCHHEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHEEECCCCEEEEECHHHHHH
IADLTARFPHEAKGIRHFYDICWQVFNCLDAMPLLSIEDPTYLAKVFFKSPLACLGLARW
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHCCHHHHHHHHH
LPVNVGDVARRHIKDPELLRFIDIECFCWSVMPADLTPMINAGMVFSDRHAGGINYPKGG
CCCCHHHHHHHHCCCCHHHHEEEEEEEEEECCCCCCCCHHCCCEEEECCCCCCCCCCCCC
VGVIAQKLVKGMQRHGGEIRYKARVTRVVLKDNRAVGVQLANGEIIHARRVISNATRWDT
HHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCEEEEEECCCCEEHHHHHHCCCCCCCC
FSGEGSKQALVDAEHTPAAEQTWRRRYVPSPSFLSLHLGVRNEAIPANSHCHHLLLESWD
CCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
EMESEQGVAFVSMPTLLDPSLSPEGHHIVHAFTPSSMQAWQDLSPATYNSKKQADADRLI
HHHHHCCEEEEECCHHCCCCCCCCCCEEEEEECCCHHHHHHCCCCCCCCCHHHCCHHHHH
RKLEKILPGLSQAIVHREVGTPRSHRRFLGRFQGSYGPIPSSRLPGLLTMPFNRTGLKGL
HHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCEE
YCVGDSCFPGQGLNAVAFSGFACSHLIGADLGINPWALPN
EEECCCCCCCCCCCCEEECCHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MEPIRIEKDATQPWDAVVIGSGIGGLVTASQLAVKGAKVLVLESYTIPGGSSGSFQREGY
CCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCE
TFDVGASMIFGFGEKGYTNLLTRALADVGEHCDTLPDPAQLAYHLPGGLELAVDRKYEQF
EEECCCHHEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHEEECCCCEEEEECHHHHHH
IADLTARFPHEAKGIRHFYDICWQVFNCLDAMPLLSIEDPTYLAKVFFKSPLACLGLARW
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHCCHHHHHHHHH
LPVNVGDVARRHIKDPELLRFIDIECFCWSVMPADLTPMINAGMVFSDRHAGGINYPKGG
CCCCHHHHHHHHCCCCHHHHEEEEEEEEEECCCCCCCCHHCCCEEEECCCCCCCCCCCCC
VGVIAQKLVKGMQRHGGEIRYKARVTRVVLKDNRAVGVQLANGEIIHARRVISNATRWDT
HHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCEEEEEECCCCEEHHHHHHCCCCCCCC
FSGEGSKQALVDAEHTPAAEQTWRRRYVPSPSFLSLHLGVRNEAIPANSHCHHLLLESWD
CCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
EMESEQGVAFVSMPTLLDPSLSPEGHHIVHAFTPSSMQAWQDLSPATYNSKKQADADRLI
HHHHHCCEEEEECCHHCCCCCCCCCCEEEEEECCCHHHHHHCCCCCCCCCHHHCCHHHHH
RKLEKILPGLSQAIVHREVGTPRSHRRFLGRFQGSYGPIPSSRLPGLLTMPFNRTGLKGL
HHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCEE
YCVGDSCFPGQGLNAVAFSGFACSHLIGADLGINPWALPN
EEECCCCCCCCCCCCEEECCHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2263648 [H]