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The map label for this gene is pepN [H]

Identifier: 124022707

GI number: 124022707

Start: 912412

End: 915030

Strand: Reverse

Name: pepN [H]

Synonym: P9303_10001

Alternate gene names: 124022707

Gene position: 915030-912412 (Counterclockwise)

Preceding gene: 124022708

Following gene: 124022705

Centisome position: 34.11

GC content: 49.14

Gene sequence:

>2619_bases
ATGACAACAGCAACCACCCGATTAGCGGATTACAGGCCATATCCCTTCCAGATTCCTAACATTGAACTGGATGTTGTTGT
CGAAGAACAGCACATCGTGATCTCCAGCTCCATGCAGATCGAGCCTGCCTTGACAACCAAAGTTCCTTTAGTCCTTCAGG
GGTTAGACCTGGAGTTGGACTCCATTGTTATAAACGGCAGTTCTGTACCAACGGATGCGTACAGCCTATCGAGCCGTGAG
TTAGTTCTCCATCAGCCACCAATTCATCCTTTTGAGTTGAAGATCATCTGCCAAATTGATCCCTTCAGCAACACCTCACT
AGAAGGGCTTTATGCCAGCGAGAGCATGCTCACAAGCCAATGTGAGGCAGAAGGCTTCCGTCGCATCTGCTTCCATCCTG
ATCGTCCTGATGTGCTCAGTCGCTATCGAGTACGAATTGAGGCGGATCGGACGCGCTATCCAGTGTTGCTCTCTAATGGA
AATCTTGTGAGCAAAGGGCCCTTACCCAAAGATCCAATGCGACATGAGGCAATTTGGGACGATCCCTATCCCAAGCCTGC
CTATCTCTTTGCTTTGGTTGCAGGGGCACTTCAGGAAGTTCAGGCTCATTTCACAACCACATATGGACGCTCAGTTCTAT
TGCGTTTGCATGTTGAGAACGGAGATGAACCCTACACCTCTCACGCCTTGGATTCTCTAAAAAAAGCTATGGCCTGGGAT
GAAAAGGTCTATGGGCTGGAGTACGACCTGGATGAATACAACATTGTGGCAGTGCGTCACTTCAACATGGGCGCAATGGA
AAATAAGAGCTTAAATATATTCAACTCAAAACTTGTCTTGGCTGATTCCGAATGTGCCACAGATAGTGAACTTGAACGAA
TCGAAAGTGTTGTTGCTCATGAATATTTTCACAACTGGACTGGCAACCGTATCACCTGCAGGGACTGGTTTCAGCTCTCT
CTAAAAGAAGGTCTCACTGTATTTCGGGATCAGAGCTTCACAGCTGATCTGCATTCAAAAGCAGTGAAACGCATCGAGGA
TGTATCAATGCTGCGAAACACCCAATTTCGTGAAGATTCAGGCCCTACATCTCATCCAGTTAAACCTAGTGAATACAAGG
CAATTGATAATTTCTACACCACAACTATTTATGAAAAAGGTGCAGAGTTAATCCGCATGCTTCACACCATGCTTGGGCAG
CAACGCTTCATGGCAGGAATGGCGTTATATGTGCAGCGTTTTGATGGCACTGCTGCTACCACAGACGATTTCATCGACTC
CATTGCTGAAGGAGCCTGCGCAAATGGGGAACAACTTGGTTTTGATCTTGATCAATTTCAGCGTTGGTATCACCAAAGCG
GAACTCCTCAAGTATGCGTCAAACGCCACTGGGATTCTCAAGTCGGAACACTCACACTTGAGGTCAGCCAGTTCACACCA
CCAACTCCTGGTCAACCCTCAAAAGAACCTCTAGTCATTCCTATGGCCCTCGCCGTGATCGGCCCAAATGGACGAGTCGG
CGAAGAGAAACTGGTTATTTTGGACCAAGACACGCAGAACGTCTCACTAAGGGATCTACCAAGACAAGCAAAGCCTCCAG
CTCTATCGATATTCCGTCGTTTTTCAGCTCCGATCACGTTGCAGATGGACGTCTCAGTCGACGAATCATTGCAGCTACTT
GCTCTTGATGACGATCCCGTTGCTCGATGGGAAGCAGGCCAGAGATTATGGAGAAAGATCCTTTTAGCAAGGGCTCGCAA
ACAAACTGACAATCCACTTGAAGAACGTTTAGCTCTAGCGTTAAATCAACTGATCACCAGTGGAGGGGAGAGTGATCCCT
CTTTTCTGGCGATGTTATTTGGCATGCCAGGACTAGCTGAACTGGAGGCCGCCCAGGATGTCGCCGATCCATTGATGCTC
TATCAGGTGTATCAATCACTCAAGTCATGGTTGGGAGTCAAACTCTCAGATCCGCTCCAGAATCTGCTTGAACGTAGTCG
ATTGAATTGGGGGGCTCAATGGCCAGCTGGACAAGGTGAACGCATGCTCACAGGACTGACCTGGAGCTGGTTAGCTGCTG
CTGGTGATTGCGAAGTTCGCAAGGAAGCAGTTGAAGCAGTCAACGGACCCTCGATGTCTTTGGCTCGAGCGGCCCTTCGG
GCACTACAACCCGTTGAATGTCCTGAGCGAGACGAAGCTCTCAAAAGCTTTTACGAGCGCTGGCAAGATCGACCAGTGAT
CCTAGATACCTGGTTTGCTCTGGAGGCATCCACTCCACGGTCAGATGGGCTTGAACGAATCAAACAGTTACTCGATCATC
CCCGCTTTGACCCAATGGCACCCAACGCGATAAGGGCTGTCCTTGGTGGTCTCGCTTCAAATCCTCCTGTATTTCACGCT
ATTGATGGAAGTGGCTACAACTTCATGGCTGATCAGCTCATCGCCATTGATCAACGCAACCCAATCACTGCTTCACGCAT
GGTGAAAGTGTTCAGTCGTTGGCAAACTTATGCTCCCTCAAGGAAAGAGGCGATGCACCGGGCCATCGATCAACTGGCCA
GTGCAGAGCTGTCTGCAAACACCAGAGAAGTGGTCACGCTCATGCAGCCAGAACAGTAG

Upstream 100 bases:

>100_bases
GAAATTGTTCCACGGTATGGCTAGCACATCTCAATTGATGTCATCAATAAATTAGCGCGGAAGCTCAAACTCAAAAATCT
CTACAAACAAACACTCCCCC

Downstream 100 bases:

>100_bases
AAACAAGCCTAGTTTTTCTTCTCATGCAATTGCTTGAACTGTCTGAGGCGCTGAATTCCACCCTCGATGCCAGCGTGCTG
TCCCCAAAGCCCCTCCCAAT

Product: aminopeptidase N

Products: NA

Alternate protein names: Alpha-aminoacylpeptide hydrolase [H]

Number of amino acids: Translated: 872; Mature: 871

Protein sequence:

>872_residues
MTTATTRLADYRPYPFQIPNIELDVVVEEQHIVISSSMQIEPALTTKVPLVLQGLDLELDSIVINGSSVPTDAYSLSSRE
LVLHQPPIHPFELKIICQIDPFSNTSLEGLYASESMLTSQCEAEGFRRICFHPDRPDVLSRYRVRIEADRTRYPVLLSNG
NLVSKGPLPKDPMRHEAIWDDPYPKPAYLFALVAGALQEVQAHFTTTYGRSVLLRLHVENGDEPYTSHALDSLKKAMAWD
EKVYGLEYDLDEYNIVAVRHFNMGAMENKSLNIFNSKLVLADSECATDSELERIESVVAHEYFHNWTGNRITCRDWFQLS
LKEGLTVFRDQSFTADLHSKAVKRIEDVSMLRNTQFREDSGPTSHPVKPSEYKAIDNFYTTTIYEKGAELIRMLHTMLGQ
QRFMAGMALYVQRFDGTAATTDDFIDSIAEGACANGEQLGFDLDQFQRWYHQSGTPQVCVKRHWDSQVGTLTLEVSQFTP
PTPGQPSKEPLVIPMALAVIGPNGRVGEEKLVILDQDTQNVSLRDLPRQAKPPALSIFRRFSAPITLQMDVSVDESLQLL
ALDDDPVARWEAGQRLWRKILLARARKQTDNPLEERLALALNQLITSGGESDPSFLAMLFGMPGLAELEAAQDVADPLML
YQVYQSLKSWLGVKLSDPLQNLLERSRLNWGAQWPAGQGERMLTGLTWSWLAAAGDCEVRKEAVEAVNGPSMSLARAALR
ALQPVECPERDEALKSFYERWQDRPVILDTWFALEASTPRSDGLERIKQLLDHPRFDPMAPNAIRAVLGGLASNPPVFHA
IDGSGYNFMADQLIAIDQRNPITASRMVKVFSRWQTYAPSRKEAMHRAIDQLASAELSANTREVVTLMQPEQ

Sequences:

>Translated_872_residues
MTTATTRLADYRPYPFQIPNIELDVVVEEQHIVISSSMQIEPALTTKVPLVLQGLDLELDSIVINGSSVPTDAYSLSSRE
LVLHQPPIHPFELKIICQIDPFSNTSLEGLYASESMLTSQCEAEGFRRICFHPDRPDVLSRYRVRIEADRTRYPVLLSNG
NLVSKGPLPKDPMRHEAIWDDPYPKPAYLFALVAGALQEVQAHFTTTYGRSVLLRLHVENGDEPYTSHALDSLKKAMAWD
EKVYGLEYDLDEYNIVAVRHFNMGAMENKSLNIFNSKLVLADSECATDSELERIESVVAHEYFHNWTGNRITCRDWFQLS
LKEGLTVFRDQSFTADLHSKAVKRIEDVSMLRNTQFREDSGPTSHPVKPSEYKAIDNFYTTTIYEKGAELIRMLHTMLGQ
QRFMAGMALYVQRFDGTAATTDDFIDSIAEGACANGEQLGFDLDQFQRWYHQSGTPQVCVKRHWDSQVGTLTLEVSQFTP
PTPGQPSKEPLVIPMALAVIGPNGRVGEEKLVILDQDTQNVSLRDLPRQAKPPALSIFRRFSAPITLQMDVSVDESLQLL
ALDDDPVARWEAGQRLWRKILLARARKQTDNPLEERLALALNQLITSGGESDPSFLAMLFGMPGLAELEAAQDVADPLML
YQVYQSLKSWLGVKLSDPLQNLLERSRLNWGAQWPAGQGERMLTGLTWSWLAAAGDCEVRKEAVEAVNGPSMSLARAALR
ALQPVECPERDEALKSFYERWQDRPVILDTWFALEASTPRSDGLERIKQLLDHPRFDPMAPNAIRAVLGGLASNPPVFHA
IDGSGYNFMADQLIAIDQRNPITASRMVKVFSRWQTYAPSRKEAMHRAIDQLASAELSANTREVVTLMQPEQ
>Mature_871_residues
TTATTRLADYRPYPFQIPNIELDVVVEEQHIVISSSMQIEPALTTKVPLVLQGLDLELDSIVINGSSVPTDAYSLSSREL
VLHQPPIHPFELKIICQIDPFSNTSLEGLYASESMLTSQCEAEGFRRICFHPDRPDVLSRYRVRIEADRTRYPVLLSNGN
LVSKGPLPKDPMRHEAIWDDPYPKPAYLFALVAGALQEVQAHFTTTYGRSVLLRLHVENGDEPYTSHALDSLKKAMAWDE
KVYGLEYDLDEYNIVAVRHFNMGAMENKSLNIFNSKLVLADSECATDSELERIESVVAHEYFHNWTGNRITCRDWFQLSL
KEGLTVFRDQSFTADLHSKAVKRIEDVSMLRNTQFREDSGPTSHPVKPSEYKAIDNFYTTTIYEKGAELIRMLHTMLGQQ
RFMAGMALYVQRFDGTAATTDDFIDSIAEGACANGEQLGFDLDQFQRWYHQSGTPQVCVKRHWDSQVGTLTLEVSQFTPP
TPGQPSKEPLVIPMALAVIGPNGRVGEEKLVILDQDTQNVSLRDLPRQAKPPALSIFRRFSAPITLQMDVSVDESLQLLA
LDDDPVARWEAGQRLWRKILLARARKQTDNPLEERLALALNQLITSGGESDPSFLAMLFGMPGLAELEAAQDVADPLMLY
QVYQSLKSWLGVKLSDPLQNLLERSRLNWGAQWPAGQGERMLTGLTWSWLAAAGDCEVRKEAVEAVNGPSMSLARAALRA
LQPVECPERDEALKSFYERWQDRPVILDTWFALEASTPRSDGLERIKQLLDHPRFDPMAPNAIRAVLGGLASNPPVFHAI
DGSGYNFMADQLIAIDQRNPITASRMVKVFSRWQTYAPSRKEAMHRAIDQLASAELSANTREVVTLMQPEQ

Specific function: Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation [H]

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cytoplasm, Bound To The Inner Face Of The Cytoplasm Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family [H]

Homologues:

Organism=Homo sapiens, GI158937236, Length=382, Percent_Identity=26.1780104712042, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI61742775, Length=336, Percent_Identity=25, Blast_Score=107, Evalue=7e-23,
Organism=Homo sapiens, GI61742777, Length=336, Percent_Identity=25, Blast_Score=107, Evalue=7e-23,
Organism=Homo sapiens, GI310123622, Length=335, Percent_Identity=25.9701492537313, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI310133497, Length=335, Percent_Identity=26.2686567164179, Blast_Score=103, Evalue=7e-22,
Organism=Homo sapiens, GI157266300, Length=397, Percent_Identity=26.7002518891688, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI4505029, Length=400, Percent_Identity=26.5, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI132814467, Length=355, Percent_Identity=24.2253521126761, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI194306629, Length=263, Percent_Identity=26.615969581749, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI11641261, Length=263, Percent_Identity=26.615969581749, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI7019561, Length=329, Percent_Identity=24.0121580547112, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI94818901, Length=314, Percent_Identity=26.4331210191083, Blast_Score=85, Evalue=4e-16,
Organism=Homo sapiens, GI94818891, Length=314, Percent_Identity=26.4331210191083, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI194239713, Length=292, Percent_Identity=25, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI54020718, Length=291, Percent_Identity=27.8350515463918, Blast_Score=77, Evalue=8e-14,
Organism=Homo sapiens, GI40316915, Length=339, Percent_Identity=24.188790560472, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1787163, Length=876, Percent_Identity=41.8949771689498, Blast_Score=624, Evalue=1e-180,
Organism=Caenorhabditis elegans, GI71989071, Length=431, Percent_Identity=25.5220417633411, Blast_Score=125, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71989076, Length=431, Percent_Identity=25.5220417633411, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17569221, Length=286, Percent_Identity=28.6713286713287, Blast_Score=100, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17569225, Length=292, Percent_Identity=26.3698630136986, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI193206928, Length=406, Percent_Identity=24.384236453202, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193206926, Length=406, Percent_Identity=24.384236453202, Blast_Score=91, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI115533278, Length=290, Percent_Identity=25.5172413793103, Blast_Score=90, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI115533276, Length=290, Percent_Identity=25.5172413793103, Blast_Score=90, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71990873, Length=483, Percent_Identity=21.9461697722567, Blast_Score=87, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17544504, Length=488, Percent_Identity=24.5901639344262, Blast_Score=87, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71984353, Length=459, Percent_Identity=22.8758169934641, Blast_Score=83, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71984339, Length=460, Percent_Identity=22.8260869565217, Blast_Score=83, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI133903840, Length=464, Percent_Identity=23.9224137931034, Blast_Score=82, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17565628, Length=322, Percent_Identity=24.5341614906832, Blast_Score=74, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI9755335, Length=417, Percent_Identity=25.1798561151079, Blast_Score=133, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6321837, Length=420, Percent_Identity=24.047619047619, Blast_Score=114, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6324283, Length=483, Percent_Identity=23.8095238095238, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24655274, Length=559, Percent_Identity=25.5813953488372, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24655260, Length=559, Percent_Identity=25.5813953488372, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24655265, Length=559, Percent_Identity=25.5813953488372, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24655268, Length=559, Percent_Identity=25.5813953488372, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24655257, Length=559, Percent_Identity=25.5813953488372, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24655252, Length=559, Percent_Identity=25.5813953488372, Blast_Score=127, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24646518, Length=363, Percent_Identity=29.2011019283747, Blast_Score=124, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24646514, Length=447, Percent_Identity=28.1879194630872, Blast_Score=124, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24646516, Length=363, Percent_Identity=29.2011019283747, Blast_Score=124, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24651025, Length=425, Percent_Identity=25.8823529411765, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24651023, Length=425, Percent_Identity=25.8823529411765, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24651021, Length=425, Percent_Identity=25.8823529411765, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21358341, Length=244, Percent_Identity=26.2295081967213, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24651016, Length=330, Percent_Identity=26.969696969697, Blast_Score=99, Evalue=2e-20,
Organism=Drosophila melanogaster, GI45550850, Length=408, Percent_Identity=24.5098039215686, Blast_Score=97, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24650973, Length=408, Percent_Identity=24.5098039215686, Blast_Score=97, Evalue=6e-20,
Organism=Drosophila melanogaster, GI221379089, Length=503, Percent_Identity=22.6640159045726, Blast_Score=90, Evalue=9e-18,
Organism=Drosophila melanogaster, GI161078673, Length=509, Percent_Identity=25.3438113948919, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28571901, Length=509, Percent_Identity=25.3438113948919, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24646510, Length=260, Percent_Identity=27.6923076923077, Blast_Score=88, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24646512, Length=260, Percent_Identity=27.6923076923077, Blast_Score=88, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24648786, Length=245, Percent_Identity=26.530612244898, Blast_Score=83, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221330574, Length=251, Percent_Identity=27.4900398406374, Blast_Score=80, Evalue=7e-15,
Organism=Drosophila melanogaster, GI28571792, Length=388, Percent_Identity=24.2268041237113, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24648790, Length=314, Percent_Identity=24.5222929936306, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24585062, Length=375, Percent_Identity=24, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24585064, Length=375, Percent_Identity=24, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24585066, Length=375, Percent_Identity=24, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45550350, Length=375, Percent_Identity=24, Blast_Score=69, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001930
- InterPro:   IPR014782
- InterPro:   IPR012779 [H]

Pfam domain/function: PF01433 Peptidase_M1 [H]

EC number: =3.4.11.2 [H]

Molecular weight: Translated: 98060; Mature: 97929

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTATTRLADYRPYPFQIPNIELDVVVEEQHIVISSSMQIEPALTTKVPLVLQGLDLELD
CCCCCCCHHCCCCCCEECCCEEEEEEEECCEEEEECCCEECCCHHCCCCEEEECCCEEEE
SIVINGSSVPTDAYSLSSRELVLHQPPIHPFELKIICQIDPFSNTSLEGLYASESMLTSQ
EEEECCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEEECCCCCCCCCCEECHHHHHHHH
CEAEGFRRICFHPDRPDVLSRYRVRIEADRTRYPVLLSNGNLVSKGPLPKDPMRHEAIWD
HHHHHHHHHCCCCCCHHHHHHEEEEEEECCCCCCEEEECCCEEECCCCCCCCCCCCCCCC
DPYPKPAYLFALVAGALQEVQAHFTTTYGRSVLLRLHVENGDEPYTSHALDSLKKAMAWD
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHC
EKVYGLEYDLDEYNIVAVRHFNMGAMENKSLNIFNSKLVLADSECATDSELERIESVVAH
HHHCCEEECCCCCEEEEEEEECCCCCCCCCEEEECCEEEEECCCCCCHHHHHHHHHHHHH
EYFHNWTGNRITCRDWFQLSLKEGLTVFRDQSFTADLHSKAVKRIEDVSMLRNTQFREDS
HHHHCCCCCEEEEHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
GPTSHPVKPSEYKAIDNFYTTTIYEKGAELIRMLHTMLGQQRFMAGMALYVQRFDGTAAT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TDDFIDSIAEGACANGEQLGFDLDQFQRWYHQSGTPQVCVKRHWDSQVGTLTLEVSQFTP
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEEEECCCC
PTPGQPSKEPLVIPMALAVIGPNGRVGEEKLVILDQDTQNVSLRDLPRQAKPPALSIFRR
CCCCCCCCCCEEEEEEEEEECCCCCCCCCEEEEEECCCCCCCHHHCCCCCCCHHHHHHHH
FSAPITLQMDVSVDESLQLLALDDDPVARWEAGQRLWRKILLARARKQTDNPLEERLALA
HCCCEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LNQLITSGGESDPSFLAMLFGMPGLAELEAAQDVADPLMLYQVYQSLKSWLGVKLSDPLQ
HHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECHHHH
NLLERSRLNWGAQWPAGQGERMLTGLTWSWLAAAGDCEVRKEAVEAVNGPSMSLARAALR
HHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHH
ALQPVECPERDEALKSFYERWQDRPVILDTWFALEASTPRSDGLERIKQLLDHPRFDPMA
HCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCC
PNAIRAVLGGLASNPPVFHAIDGSGYNFMADQLIAIDQRNPITASRMVKVFSRWQTYAPS
CHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHEEEECCCCCCCHHHHHHHHHHHHHCCCC
RKEAMHRAIDQLASAELSANTREVVTLMQPEQ
HHHHHHHHHHHHHHHHHCCCCHHEEEEECCCC
>Mature Secondary Structure 
TTATTRLADYRPYPFQIPNIELDVVVEEQHIVISSSMQIEPALTTKVPLVLQGLDLELD
CCCCCCHHCCCCCCEECCCEEEEEEEECCEEEEECCCEECCCHHCCCCEEEECCCEEEE
SIVINGSSVPTDAYSLSSRELVLHQPPIHPFELKIICQIDPFSNTSLEGLYASESMLTSQ
EEEECCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEEECCCCCCCCCCEECHHHHHHHH
CEAEGFRRICFHPDRPDVLSRYRVRIEADRTRYPVLLSNGNLVSKGPLPKDPMRHEAIWD
HHHHHHHHHCCCCCCHHHHHHEEEEEEECCCCCCEEEECCCEEECCCCCCCCCCCCCCCC
DPYPKPAYLFALVAGALQEVQAHFTTTYGRSVLLRLHVENGDEPYTSHALDSLKKAMAWD
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHC
EKVYGLEYDLDEYNIVAVRHFNMGAMENKSLNIFNSKLVLADSECATDSELERIESVVAH
HHHCCEEECCCCCEEEEEEEECCCCCCCCCEEEECCEEEEECCCCCCHHHHHHHHHHHHH
EYFHNWTGNRITCRDWFQLSLKEGLTVFRDQSFTADLHSKAVKRIEDVSMLRNTQFREDS
HHHHCCCCCEEEEHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
GPTSHPVKPSEYKAIDNFYTTTIYEKGAELIRMLHTMLGQQRFMAGMALYVQRFDGTAAT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TDDFIDSIAEGACANGEQLGFDLDQFQRWYHQSGTPQVCVKRHWDSQVGTLTLEVSQFTP
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEEEECCCC
PTPGQPSKEPLVIPMALAVIGPNGRVGEEKLVILDQDTQNVSLRDLPRQAKPPALSIFRR
CCCCCCCCCCEEEEEEEEEECCCCCCCCCEEEEEECCCCCCCHHHCCCCCCCHHHHHHHH
FSAPITLQMDVSVDESLQLLALDDDPVARWEAGQRLWRKILLARARKQTDNPLEERLALA
HCCCEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LNQLITSGGESDPSFLAMLFGMPGLAELEAAQDVADPLMLYQVYQSLKSWLGVKLSDPLQ
HHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECHHHH
NLLERSRLNWGAQWPAGQGERMLTGLTWSWLAAAGDCEVRKEAVEAVNGPSMSLARAALR
HHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHH
ALQPVECPERDEALKSFYERWQDRPVILDTWFALEASTPRSDGLERIKQLLDHPRFDPMA
HCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCC
PNAIRAVLGGLASNPPVFHAIDGSGYNFMADQLIAIDQRNPITASRMVKVFSRWQTYAPS
CHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHEEEECCCCCCCHHHHHHHHHHHHHCCCC
RKEAMHRAIDQLASAELSANTREVVTLMQPEQ
HHHHHHHHHHHHHHHHHCCCCHHEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647; 8421698 [H]