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The map label for this gene is prmA

Identifier: 124022235

GI number: 124022235

Start: 513499

End: 514404

Strand: Direct

Name: prmA

Synonym: P9303_05251

Alternate gene names: 124022235

Gene position: 513499-514404 (Clockwise)

Preceding gene: 124022234

Following gene: 124022236

Centisome position: 19.14

GC content: 55.85

Gene sequence:

>906_bases
ATGAACTCTGCTTCTGCTTGTTGCTGGTGGCGTCTTGCCCTGCCCATTGCAGATGAACTGGAAGAGTCGCTCATCTGGAA
GCTGACAGAGCTGGGCATCTCTCGAATCGCTGTTCAACATGTACCTGAGAAGGCTGAGCGCACCCTGTTGGCATGGTTGC
CATCGTCTGAGTGGTCCGAGTCGGACAGAGATCAGCTGATGGTCAACCTGCGTCCTCTGGCAGAACCATTTGGCCTGCAA
TTAGCCAACCCCACTTGGTGCGAGGTGGCCGATGAAGACTGGAGTTTGAACTGGAAGCAACATTGGCAATCCGATCCGGT
GGGGCAGCGTCTATTGATCTTGCCGGCTTGGTTGGATCTGCCGCAGGAGTATGCCGATCGGCTTGTTGTGCGAATGGACC
CTGGCAGTGCTTTTGGTACTGGCAGCCATCCCAGCACTCGCCTTTGCCTGGAGGCGCTAGAGAAGAACCCCCCGCTGGGC
TTGAGGGTGGCAGATCTCGGCTGTGGCAGTGGGGTGTTGGGTTTCGCCGCATTGGGTTTTGGGGCCAGGCAGGTGCTGGC
CGCTGATACGGATTCTCAGGCTGTCTGCGCCTCTAGAGCCAATGCAGAGCTCAATCAGCTCGATTTAGATCGTTTCAGGG
TTGTGCATGGTTCTGTGGATGCTTTGTCAGCGCAGTTGCAGGGAGAGGTCGTCGACCTACTGCTCTGCAACATCCTTGCT
CCTGTGATTGAGGCTTTGGCTTCAAGCTTTGATCAGTTGTTGAGTGCGAATGGTCGATGTTTGCTCAGTGGTTTGCTGGT
TGATCAAGCGCCAAGGCTTCAGGTGGTTTTGGAGGCGCTGGGATGGCGGGTGAATAGCCTGACTGTGCAGGGCTGCTGGG
GGCTTTTAGATGTTTCTAAGCGGTAA

Upstream 100 bases:

>100_bases
GCATTGATGATCCAATCCCACCAAGTTTGCTGGTCACCATCCATGCGATCAATGGCATTAAGGAAGCTCATCCGGTCACC
CTCTGATCGAGGCTGATGAG

Downstream 100 bases:

>100_bases
TTCTGCGCAAATTTTTATATAAGCCAGAGTTATCTGTACTCGTTCTTTGATTGGCCTTAGTCGGGCAGATTGCACGATCA
GACTGTATTTTTGCTGTGAG

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MNSASACCWWRLALPIADELEESLIWKLTELGISRIAVQHVPEKAERTLLAWLPSSEWSESDRDQLMVNLRPLAEPFGLQ
LANPTWCEVADEDWSLNWKQHWQSDPVGQRLLILPAWLDLPQEYADRLVVRMDPGSAFGTGSHPSTRLCLEALEKNPPLG
LRVADLGCGSGVLGFAALGFGARQVLAADTDSQAVCASRANAELNQLDLDRFRVVHGSVDALSAQLQGEVVDLLLCNILA
PVIEALASSFDQLLSANGRCLLSGLLVDQAPRLQVVLEALGWRVNSLTVQGCWGLLDVSKR

Sequences:

>Translated_301_residues
MNSASACCWWRLALPIADELEESLIWKLTELGISRIAVQHVPEKAERTLLAWLPSSEWSESDRDQLMVNLRPLAEPFGLQ
LANPTWCEVADEDWSLNWKQHWQSDPVGQRLLILPAWLDLPQEYADRLVVRMDPGSAFGTGSHPSTRLCLEALEKNPPLG
LRVADLGCGSGVLGFAALGFGARQVLAADTDSQAVCASRANAELNQLDLDRFRVVHGSVDALSAQLQGEVVDLLLCNILA
PVIEALASSFDQLLSANGRCLLSGLLVDQAPRLQVVLEALGWRVNSLTVQGCWGLLDVSKR
>Mature_301_residues
MNSASACCWWRLALPIADELEESLIWKLTELGISRIAVQHVPEKAERTLLAWLPSSEWSESDRDQLMVNLRPLAEPFGLQ
LANPTWCEVADEDWSLNWKQHWQSDPVGQRLLILPAWLDLPQEYADRLVVRMDPGSAFGTGSHPSTRLCLEALEKNPPLG
LRVADLGCGSGVLGFAALGFGARQVLAADTDSQAVCASRANAELNQLDLDRFRVVHGSVDALSAQLQGEVVDLLLCNILA
PVIEALASSFDQLLSANGRCLLSGLLVDQAPRLQVVLEALGWRVNSLTVQGCWGLLDVSKR

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=160, Percent_Identity=40.625, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_PROM3 (A2C717)

Other databases:

- EMBL:   CP000554
- RefSeq:   YP_001016542.1
- ProteinModelPortal:   A2C717
- SMR:   A2C717
- STRING:   A2C717
- GeneID:   4777423
- GenomeReviews:   CP000554_GR
- KEGG:   pmf:P9303_05251
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   MSFGTGY
- ProtClustDB:   PRK00517
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32950; Mature: 32950

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSASACCWWRLALPIADELEESLIWKLTELGISRIAVQHVPEKAERTLLAWLPSSEWSE
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCEEEEECCCCCCCC
SDRDQLMVNLRPLAEPFGLQLANPTWCEVADEDWSLNWKQHWQSDPVGQRLLILPAWLDL
CCCHHEEEEEECCCCCCCCEECCCCEEEECCCCCCCCHHHHCCCCCCCCEEEEEEHHHCC
PQEYADRLVVRMDPGSAFGTGSHPSTRLCLEALEKNPPLGLRVADLGCGSGVLGFAALGF
CHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHCC
GARQVLAADTDSQAVCASRANAELNQLDLDRFRVVHGSVDALSAQLQGEVVDLLLCNILA
CHHHEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
PVIEALASSFDQLLSANGRCLLSGLLVDQAPRLQVVLEALGWRVNSLTVQGCWGLLDVSK
HHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCHHHHHHHHHCCEEEEEEEECCCCEEECCC
R
C
>Mature Secondary Structure
MNSASACCWWRLALPIADELEESLIWKLTELGISRIAVQHVPEKAERTLLAWLPSSEWSE
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCEEEEECCCCCCCC
SDRDQLMVNLRPLAEPFGLQLANPTWCEVADEDWSLNWKQHWQSDPVGQRLLILPAWLDL
CCCHHEEEEEECCCCCCCCEECCCCEEEECCCCCCCCHHHHCCCCCCCCEEEEEEHHHCC
PQEYADRLVVRMDPGSAFGTGSHPSTRLCLEALEKNPPLGLRVADLGCGSGVLGFAALGF
CHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHCC
GARQVLAADTDSQAVCASRANAELNQLDLDRFRVVHGSVDALSAQLQGEVVDLLLCNILA
CHHHEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
PVIEALASSFDQLLSANGRCLLSGLLVDQAPRLQVVLEALGWRVNSLTVQGCWGLLDVSK
HHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCHHHHHHHHHCCEEEEEEEECCCCEEECCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA