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The map label for this gene is mpg1 [H]

Identifier: 124021811

GI number: 124021811

Start: 97950

End: 98708

Strand: Direct

Name: mpg1 [H]

Synonym: P9303_00981

Alternate gene names: 124021811

Gene position: 97950-98708 (Clockwise)

Preceding gene: 124021810

Following gene: 124021812

Centisome position: 3.65

GC content: 37.94

Gene sequence:

>759_bases
ATGTATGCTCAATGCGAGATTCGAGCATTAGTATTAGCGGCTGGTAAGGGCACTAGGTTGCAGCCCCTTACGTTGACAAT
CCCTAAATGTCTCGTATCTGTGGGCGGGAAGCCACTCTTAAAAAGATGGCTAGAATCATTAGAGGATATAGATTGTCGAT
CTGTAATTATCAATACTCATTACCTACATGATCAGGTTGAAGACTATATCAAAAATCAAGATGTTGGAAAGATTTCTGTA
ATACTAAAATACGAACCTAAGTTGCTTGGTACAGCAGGCACATTGTATCAAAACCGATTTTGGTTTAGAGGATGTATGAA
TTTAATCATTCATTGCGATAATTACTACGATGGTAGGCTCGAGCTTTTACTGAATGCACATAAGGAAAGGAGTCAAAAAT
GTATACTGACAATGCTCACATTTGACTGTGATGATCCGAGCTCATGTGGCATAACTCAGGTAAACCAGGATGGAATATTG
ACTGGCTTTCATGAAAAAAGCCAAAATTTTAAAGGTACAATGGCGAATGCAGCAATTTATGTATTCGAAGATGACTTCCT
AGACTGGCTTGAAAATGAAAGTAATTTATTTGACATTAGCTTAGATATAATTCCCAAATTATTAGGTAAAATACAGACTG
TTCATACAATGGATAAGTTGGTAGACATAGGCACTTTGGAGCGGCTTAACAAGCTAGAATTGGAATTGAACGATGTCAAG
ACTAGAACAAATGAACCATTTCGGACGGAGAGGCGGTGA

Upstream 100 bases:

>100_bases
TTCTGAAATTCAATTGGATGTATAGAATCTTAAATACAGGAGTATGGGACGTTTGATTATATTATGTTAGCTTGTATCGG
TCTATATACGGTAATCTTTA

Downstream 100 bases:

>100_bases
ATATCTCGAAAAATTGTGTGGATCCTTCAACAATGAAATTTACCAGAAGATTGATGAATTATGTAATGATCTAATTGGTG
CATGGAAGAATCATAAAGTT

Product: sugar-phosphate nucleotidyl transferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MYAQCEIRALVLAAGKGTRLQPLTLTIPKCLVSVGGKPLLKRWLESLEDIDCRSVIINTHYLHDQVEDYIKNQDVGKISV
ILKYEPKLLGTAGTLYQNRFWFRGCMNLIIHCDNYYDGRLELLLNAHKERSQKCILTMLTFDCDDPSSCGITQVNQDGIL
TGFHEKSQNFKGTMANAAIYVFEDDFLDWLENESNLFDISLDIIPKLLGKIQTVHTMDKLVDIGTLERLNKLELELNDVK
TRTNEPFRTERR

Sequences:

>Translated_252_residues
MYAQCEIRALVLAAGKGTRLQPLTLTIPKCLVSVGGKPLLKRWLESLEDIDCRSVIINTHYLHDQVEDYIKNQDVGKISV
ILKYEPKLLGTAGTLYQNRFWFRGCMNLIIHCDNYYDGRLELLLNAHKERSQKCILTMLTFDCDDPSSCGITQVNQDGIL
TGFHEKSQNFKGTMANAAIYVFEDDFLDWLENESNLFDISLDIIPKLLGKIQTVHTMDKLVDIGTLERLNKLELELNDVK
TRTNEPFRTERR
>Mature_252_residues
MYAQCEIRALVLAAGKGTRLQPLTLTIPKCLVSVGGKPLLKRWLESLEDIDCRSVIINTHYLHDQVEDYIKNQDVGKISV
ILKYEPKLLGTAGTLYQNRFWFRGCMNLIIHCDNYYDGRLELLLNAHKERSQKCILTMLTFDCDDPSSCGITQVNQDGIL
TGFHEKSQNFKGTMANAAIYVFEDDFLDWLENESNLFDISLDIIPKLLGKIQTVHTMDKLVDIGTLERLNKLELELNDVK
TRTNEPFRTERR

Specific function: Glycogen biosynthesis; first step. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=222, Percent_Identity=27.027027027027, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI11761619, Length=222, Percent_Identity=27.027027027027, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI133931050, Length=185, Percent_Identity=31.3513513513514, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6320148, Length=190, Percent_Identity=26.8421052631579, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21355443, Length=219, Percent_Identity=31.9634703196347, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24644084, Length=219, Percent_Identity=31.9634703196347, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24653912, Length=198, Percent_Identity=25.7575757575758, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 28917; Mature: 28917

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYAQCEIRALVLAAGKGTRLQPLTLTIPKCLVSVGGKPLLKRWLESLEDIDCRSVIINTH
CCCCEEEEEEEEECCCCCEEEEEEEHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEHH
YLHDQVEDYIKNQDVGKISVILKYEPKLLGTAGTLYQNRFWFRGCMNLIIHCDNYYDGRL
HHHHHHHHHHCCCCCCEEEEEEEECCCEECCCHHHHHHHHHHHHHHHHEEEECCCCCCHH
ELLLNAHKERSQKCILTMLTFDCDDPSSCGITQVNQDGILTGFHEKSQNFKGTMANAAIY
HHEEHHHHHHCCEEEEEEEEECCCCCCCCCCEEECCCCCEECCHHCCCCCCCEECCEEEE
VFEDDFLDWLENESNLFDISLDIIPKLLGKIQTVHTMDKLVDIGTLERLNKLELELNDVK
EEECHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHH
TRTNEPFRTERR
CCCCCCCCCCCC
>Mature Secondary Structure
MYAQCEIRALVLAAGKGTRLQPLTLTIPKCLVSVGGKPLLKRWLESLEDIDCRSVIINTH
CCCCEEEEEEEEECCCCCEEEEEEEHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEHH
YLHDQVEDYIKNQDVGKISVILKYEPKLLGTAGTLYQNRFWFRGCMNLIIHCDNYYDGRL
HHHHHHHHHHCCCCCCEEEEEEEECCCEECCCHHHHHHHHHHHHHHHHEEEECCCCCCHH
ELLLNAHKERSQKCILTMLTFDCDDPSSCGITQVNQDGILTGFHEKSQNFKGTMANAAIY
HHEEHHHHHHCCEEEEEEEEECCCCCCCCCCEEECCCCCEECCHHCCCCCCCEECCEEEE
VFEDDFLDWLENESNLFDISLDIIPKLLGKIQTVHTMDKLVDIGTLERLNKLELELNDVK
EEECHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHH
TRTNEPFRTERR
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]