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The map label for this gene is gmhB [H]

Identifier: 124021810

GI number: 124021810

Start: 97134

End: 97796

Strand: Direct

Name: gmhB [H]

Synonym: P9303_00971

Alternate gene names: 124021810

Gene position: 97134-97796 (Clockwise)

Preceding gene: 124021809

Following gene: 124021811

Centisome position: 3.62

GC content: 33.79

Gene sequence:

>663_bases
ATGAACAGACACATAATACATACTATAAAAAGTAGTAGAGAAATACTAGGAATAAATAACAAGTGTTTATTCCTAGACAG
GGATGGCGTTATTATAAAAGATAAAAACTACATCAGCTCTCCTTTAGAAGTAGAGCTGGAGAAAGGTGCAAAGTATTTGA
TTAACCTAGCAAAGAAAAATCATTATCTTGTGGTCATTATTACTAACCAATCTGGGATCTCTCGAGGTTATTTTAATTGG
AATCAATACGAGGAAGTTACTAAAGAAATGATTAAGCAGCTTGGTGGTGAGATGATGGTTGATGGTATTTATGCAAATGG
AATTTATCCAGATGCGTCTACAAAAGCCGATAGCTGGAGAAAACCTGGGATTGGTATGATTATTCAAGCAAAGAACGACT
TCAATATAGAATTAAAAGACTCTATTTTAATTGGTGATAGATTGAGTGATATTCTTTCAGGTTTACGTGCTGGATTAGGA
CATGTCATACATGTAGAGACTGGCCATGGGCATAAAGAAAGATCCAAAGTGGAAAAATATTTAGTTCGAGAAACACCAAA
TATGATATGTTTCGAGGAAGATGGAACAAAAACAAACTTTACGAGGTTAACAAGTCTAGAGGAATTAGACAAGGAGGATA
TAAATATATTTTCCAGTACTTAA

Upstream 100 bases:

>100_bases
GAGCGTGTAAAAACTGGTATTGATAAATTTGAGTATAAAAAATTAAAAAAATCTAAAATGATAAAGGCTAGGCGGATATA
AACTTATAGTTATTTCAAAA

Downstream 100 bases:

>100_bases
ATTGATGGCAATATGTCAGAATTATCCATATACTTGGTGAGGCGTTAGATAGATTCTGAAATTCAATTGGATGTATAGAA
TCTTAAATACAGGAGTATGG

Product: phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MNRHIIHTIKSSREILGINNKCLFLDRDGVIIKDKNYISSPLEVELEKGAKYLINLAKKNHYLVVIITNQSGISRGYFNW
NQYEEVTKEMIKQLGGEMMVDGIYANGIYPDASTKADSWRKPGIGMIIQAKNDFNIELKDSILIGDRLSDILSGLRAGLG
HVIHVETGHGHKERSKVEKYLVRETPNMICFEEDGTKTNFTRLTSLEELDKEDINIFSST

Sequences:

>Translated_220_residues
MNRHIIHTIKSSREILGINNKCLFLDRDGVIIKDKNYISSPLEVELEKGAKYLINLAKKNHYLVVIITNQSGISRGYFNW
NQYEEVTKEMIKQLGGEMMVDGIYANGIYPDASTKADSWRKPGIGMIIQAKNDFNIELKDSILIGDRLSDILSGLRAGLG
HVIHVETGHGHKERSKVEKYLVRETPNMICFEEDGTKTNFTRLTSLEELDKEDINIFSST
>Mature_220_residues
MNRHIIHTIKSSREILGINNKCLFLDRDGVIIKDKNYISSPLEVELEKGAKYLINLAKKNHYLVVIITNQSGISRGYFNW
NQYEEVTKEMIKQLGGEMMVDGIYANGIYPDASTKADSWRKPGIGMIIQAKNDFNIELKDSILIGDRLSDILSGLRAGLG
HVIHVETGHGHKERSKVEKYLVRETPNMICFEEDGTKTNFTRLTSLEELDKEDINIFSST

Specific function: Converts the D-glycero-alpha-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-alpha-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=152, Percent_Identity=33.5526315789474, Blast_Score=84, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 24989; Mature: 24989

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRHIIHTIKSSREILGINNKCLFLDRDGVIIKDKNYISSPLEVELEKGAKYLINLAKKN
CCCEEEEEECCCCEEEECCCEEEEEECCCEEEECCCCCCCCCEEEECCCCCEEHHHHCCC
HYLVVIITNQSGISRGYFNWNQYEEVTKEMIKQLGGEMMVDGIYANGIYPDASTKADSWR
CEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCC
KPGIGMIIQAKNDFNIELKDSILIGDRLSDILSGLRAGLGHVIHVETGHGHKERSKVEKY
CCCCEEEEEECCCCCEEEECCEEECHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHH
LVRETPNMICFEEDGTKTNFTRLTSLEELDKEDINIFSST
HHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCEEEECC
>Mature Secondary Structure
MNRHIIHTIKSSREILGINNKCLFLDRDGVIIKDKNYISSPLEVELEKGAKYLINLAKKN
CCCEEEEEECCCCEEEECCCEEEEEECCCEEEECCCCCCCCCEEEECCCCCEEHHHHCCC
HYLVVIITNQSGISRGYFNWNQYEEVTKEMIKQLGGEMMVDGIYANGIYPDASTKADSWR
CEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCC
KPGIGMIIQAKNDFNIELKDSILIGDRLSDILSGLRAGLGHVIHVETGHGHKERSKVEKY
CCCCEEEEEECCCCCEEEECCEEECHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHH
LVRETPNMICFEEDGTKTNFTRLTSLEELDKEDINIFSST
HHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11279237; 12101286 [H]