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The map label for this gene is pabB [H]

Identifier: 124026871

GI number: 124026871

Start: 1823252

End: 1824592

Strand: Direct

Name: pabB [H]

Synonym: NATL1_21661

Alternate gene names: 124026871

Gene position: 1823252-1824592 (Clockwise)

Preceding gene: 124026870

Following gene: 124026872

Centisome position: 97.78

GC content: 38.26

Gene sequence:

>1341_bases
GTGAATAATATTAAACGACTACTATGTCAGTGGGAATCACCTGAGCAAGTAGCCTATAAATTGATTCAAGAATGGGGAGA
GGCGGGATTTATATGGCTTGATGGCGATGGGAGTGATTTAGGTCGATGGGTCACCTTAGGAATTAATCCTTTAGAACAGT
TTTGCTCTAGAGAATTAGAAAATTCAAAAAAGTACTCTAATCCTTTTAAAATTTTACGCGAATTACCCCAAGGGCATTGG
ACTGGTTGGTTGAGTTATGAAGCTGCATCTTGGACAGAACCACAAAACCCATGGCAAAAAAGTTCCATGGCAACTTTATG
GATAGCCTCTCATGACCCAATATTAAAATTTGATCTTCAGAAGAGAGAGCTATGGCTAGAAGGCAAAGATCCAAAACGCA
TCTCTATTATGGAAAATTTTCTAAAAAGTACTTTTCATCAAAAGCTTTCTAAACCAGACAGTGAAGCAGCAAAACAAGCA
GAATGCAAACATAGTATTCCCCTAGAATCTTGGGACTGGCGGTTAACAAGTCAAGAATATTCTGAAAGAGTTGATGAGAT
CAAAGAATGGATTGCGAACGGTGATATTTTTCAGGCTAATCTAACTACCTCATGCCAAGCCCCATTGCCAGAATCAATGC
GTCCAATAGACGTATATTCAAAACTTAAAAAATACTCCCCTGCTCCATTTGCTGGAGTAATTATCGGCGATCAGATGGCA
AAAGGAGAAGCTATTATATCAACTTCACCAGAAAGATTTTTAAAAGCGTTACCCAGTGGTGAGGTGGAAACGAGACCAAT
CAAAGGTACTAGACCAAGAGATAGAGATCCAGAAAAAGATGCTGATTGGGCAGCAGAGCTTATTTGTAGTCCAAAAGATC
ATGCTGAGAATGTAATGATTGTAGATCTACTAAGAAATGATCTTGGAAGAGTATGCCAACCTGGTTCAATCAATGTTCCT
CATCTACTAGTTTTAGAAAGCTATTCACAAGTTCATCATCTCACTTCAGTAGTTAAAGGTAGACTCAATACAAATAAGAC
TTGGGTTGACTTACTTGAAGCCTGCTGGCCAGGAGGTTCAGTAACAGGAGCACCGAAGCTTAGAGCATGTAAAAGATTGT
ATGAACTTGAACCAACAGCGAGAGGTCCATATTGTGGATCAATATTAAATATAAATTGGGATGGAGTACTTGATAGTAAT
ATTCTCATTCGATCTTTAATGATTAAAGAATCTTCTATCAGTGCTCATGCTGGATGTGGAATTGTTGCAGATTCAGATAG
TCAAAAGGAAGCTGAAGAAATGAATTGGAAATTGATGCCACTTTTAAACGCATTAACATGA

Upstream 100 bases:

>100_bases
AAGGTGAAAGTAAACCGTGTGGGAGATGTGATAGTTGTCGTATTAGAGATAAAGCATTAAAAGAAATAGGTCGCGAAGAT
CTATGTAGTCAAAATATCTA

Downstream 100 bases:

>100_bases
CTGAAAATAAGAACGAAAAATTAGGATGGATTAATGGTCATTGGGGAGTCTTCAAAGATTTAAAAGTGCCAATTAATGAT
CGAGGTCTCAACTTTGCGGA

Product: putative p-aminobenzoate synthetase

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MNNIKRLLCQWESPEQVAYKLIQEWGEAGFIWLDGDGSDLGRWVTLGINPLEQFCSRELENSKKYSNPFKILRELPQGHW
TGWLSYEAASWTEPQNPWQKSSMATLWIASHDPILKFDLQKRELWLEGKDPKRISIMENFLKSTFHQKLSKPDSEAAKQA
ECKHSIPLESWDWRLTSQEYSERVDEIKEWIANGDIFQANLTTSCQAPLPESMRPIDVYSKLKKYSPAPFAGVIIGDQMA
KGEAIISTSPERFLKALPSGEVETRPIKGTRPRDRDPEKDADWAAELICSPKDHAENVMIVDLLRNDLGRVCQPGSINVP
HLLVLESYSQVHHLTSVVKGRLNTNKTWVDLLEACWPGGSVTGAPKLRACKRLYELEPTARGPYCGSILNINWDGVLDSN
ILIRSLMIKESSISAHAGCGIVADSDSQKEAEEMNWKLMPLLNALT

Sequences:

>Translated_446_residues
MNNIKRLLCQWESPEQVAYKLIQEWGEAGFIWLDGDGSDLGRWVTLGINPLEQFCSRELENSKKYSNPFKILRELPQGHW
TGWLSYEAASWTEPQNPWQKSSMATLWIASHDPILKFDLQKRELWLEGKDPKRISIMENFLKSTFHQKLSKPDSEAAKQA
ECKHSIPLESWDWRLTSQEYSERVDEIKEWIANGDIFQANLTTSCQAPLPESMRPIDVYSKLKKYSPAPFAGVIIGDQMA
KGEAIISTSPERFLKALPSGEVETRPIKGTRPRDRDPEKDADWAAELICSPKDHAENVMIVDLLRNDLGRVCQPGSINVP
HLLVLESYSQVHHLTSVVKGRLNTNKTWVDLLEACWPGGSVTGAPKLRACKRLYELEPTARGPYCGSILNINWDGVLDSN
ILIRSLMIKESSISAHAGCGIVADSDSQKEAEEMNWKLMPLLNALT
>Mature_446_residues
MNNIKRLLCQWESPEQVAYKLIQEWGEAGFIWLDGDGSDLGRWVTLGINPLEQFCSRELENSKKYSNPFKILRELPQGHW
TGWLSYEAASWTEPQNPWQKSSMATLWIASHDPILKFDLQKRELWLEGKDPKRISIMENFLKSTFHQKLSKPDSEAAKQA
ECKHSIPLESWDWRLTSQEYSERVDEIKEWIANGDIFQANLTTSCQAPLPESMRPIDVYSKLKKYSPAPFAGVIIGDQMA
KGEAIISTSPERFLKALPSGEVETRPIKGTRPRDRDPEKDADWAAELICSPKDHAENVMIVDLLRNDLGRVCQPGSINVP
HLLVLESYSQVHHLTSVVKGRLNTNKTWVDLLEACWPGGSVTGAPKLRACKRLYELEPTARGPYCGSILNINWDGVLDSN
ILIRSLMIKESSISAHAGCGIVADSDSQKEAEEMNWKLMPLLNALT

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=275, Percent_Identity=41.4545454545455, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1787518, Length=288, Percent_Identity=33.6805555555556, Blast_Score=150, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6320935, Length=430, Percent_Identity=29.7674418604651, Blast_Score=176, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6324361, Length=286, Percent_Identity=30.0699300699301, Blast_Score=99, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 50454; Mature: 50454

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNIKRLLCQWESPEQVAYKLIQEWGEAGFIWLDGDGSDLGRWVTLGINPLEQFCSRELE
CCHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEECCCHHHHHHHHHHH
NSKKYSNPFKILRELPQGHWTGWLSYEAASWTEPQNPWQKSSMATLWIASHDPILKFDLQ
HCCCCCCHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHCCCEEEEEECCCCEEEEECC
KRELWLEGKDPKRISIMENFLKSTFHQKLSKPDSEAAKQAECKHSIPLESWDWRLTSQEY
CCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEECHHHH
SERVDEIKEWIANGDIFQANLTTSCQAPLPESMRPIDVYSKLKKYSPAPFAGVIIGDQMA
HHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCC
KGEAIISTSPERFLKALPSGEVETRPIKGTRPRDRDPEKDADWAAELICSPKDHAENVMI
CCCEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHCCCEEH
VDLLRNDLGRVCQPGSINVPHLLVLESYSQVHHLTSVVKGRLNTNKTWVDLLEACWPGGS
HHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCC
VTGAPKLRACKRLYELEPTARGPYCGSILNINWDGVLDSNILIRSLMIKESSISAHAGCG
CCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEECCHHHHHHHHHHHCCCCCCCCCC
IVADSDSQKEAEEMNWKLMPLLNALT
EEECCCCHHHHHHCCEEHHHHHHHCC
>Mature Secondary Structure
MNNIKRLLCQWESPEQVAYKLIQEWGEAGFIWLDGDGSDLGRWVTLGINPLEQFCSRELE
CCHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEECCCHHHHHHHHHHH
NSKKYSNPFKILRELPQGHWTGWLSYEAASWTEPQNPWQKSSMATLWIASHDPILKFDLQ
HCCCCCCHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHCCCEEEEEECCCCEEEEECC
KRELWLEGKDPKRISIMENFLKSTFHQKLSKPDSEAAKQAECKHSIPLESWDWRLTSQEY
CCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEECHHHH
SERVDEIKEWIANGDIFQANLTTSCQAPLPESMRPIDVYSKLKKYSPAPFAGVIIGDQMA
HHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCC
KGEAIISTSPERFLKALPSGEVETRPIKGTRPRDRDPEKDADWAAELICSPKDHAENVMI
CCCEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHCCCEEH
VDLLRNDLGRVCQPGSINVPHLLVLESYSQVHHLTSVVKGRLNTNKTWVDLLEACWPGGS
HHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCC
VTGAPKLRACKRLYELEPTARGPYCGSILNINWDGVLDSNILIRSLMIKESSISAHAGCG
CCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEECCHHHHHHHHHHHCCCCCCCCCC
IVADSDSQKEAEEMNWKLMPLLNALT
EEECCCCHHHHHHCCEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]