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The map label for this gene is queC

Identifier: 124026870

GI number: 124026870

Start: 1822575

End: 1823252

Strand: Direct

Name: queC

Synonym: NATL1_21651

Alternate gene names: 124026870

Gene position: 1822575-1823252 (Clockwise)

Preceding gene: 124026869

Following gene: 124026871

Centisome position: 97.74

GC content: 37.76

Gene sequence:

>678_bases
ATGATTGAACAGACAACAATTGCATTACTTTCTGGAGGAATTGATTCAGCTACAGCTGCATGTATCGCTATGGAAGCTGG
GCAAAAAGTAATTGGATTATCATTTGATTATGGCCAGCGACATCTTAAGGAGTTACAAGCAGCAGCAGATTTAGCAAAAA
ATTTAAATCTTGAGGATCATATAACAATAAAGATTGATTTATCTTCTTGGGGTGGTTCCTCCTTGACCGACACGTCACAA
GCAATACCAACTAAAGGCATACAAAAAAATACTATTCCTAACACTTACGTTCCTGGTAGAAACACTATCTTTGTTGCTAT
TGGTTTGAGTCTTGCAGAAGCACGTGGAGCCAATCGAATCGCATTAGGAATAAATGCAATGGACTATTCTGGATATCCAG
ACTGTAGACCGGATTATTTAAAAGCATATCAAGAATTAGCTAACCTATCGAGCAGAGTAGGACGCGAGGGAAAAGGGATA
AAACTATGGGCTCCACTACTAGATTGGGAAAAAACAAAAATCTTTGAGGAGGCATTACGCTTAAAAATTCCTATAGAAAA
AACATGGAGTTGCTATCAAGGTGAAAGTAAACCGTGTGGGAGATGTGATAGTTGTCGTATTAGAGATAAAGCATTAAAAG
AAATAGGTCGCGAAGATCTATGTAGTCAAAATATCTAG

Upstream 100 bases:

>100_bases
CCGGATTGGAGATTAAGTATGCAAACTCACAAATGGCTAGGTGTACTCTAACCATCTATATAAATGAGATTTTGCTTCAT
TAGATTTAAAAATAAAAATA

Downstream 100 bases:

>100_bases
TGAATAATATTAAACGACTACTATGTCAGTGGGAATCACCTGAGCAAGTAGCCTATAAATTGATTCAAGAATGGGGAGAG
GCGGGATTTATATGGCTTGA

Product: ATPase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MIEQTTIALLSGGIDSATAACIAMEAGQKVIGLSFDYGQRHLKELQAAADLAKNLNLEDHITIKIDLSSWGGSSLTDTSQ
AIPTKGIQKNTIPNTYVPGRNTIFVAIGLSLAEARGANRIALGINAMDYSGYPDCRPDYLKAYQELANLSSRVGREGKGI
KLWAPLLDWEKTKIFEEALRLKIPIEKTWSCYQGESKPCGRCDSCRIRDKALKEIGREDLCSQNI

Sequences:

>Translated_225_residues
MIEQTTIALLSGGIDSATAACIAMEAGQKVIGLSFDYGQRHLKELQAAADLAKNLNLEDHITIKIDLSSWGGSSLTDTSQ
AIPTKGIQKNTIPNTYVPGRNTIFVAIGLSLAEARGANRIALGINAMDYSGYPDCRPDYLKAYQELANLSSRVGREGKGI
KLWAPLLDWEKTKIFEEALRLKIPIEKTWSCYQGESKPCGRCDSCRIRDKALKEIGREDLCSQNI
>Mature_225_residues
MIEQTTIALLSGGIDSATAACIAMEAGQKVIGLSFDYGQRHLKELQAAADLAKNLNLEDHITIKIDLSSWGGSSLTDTSQ
AIPTKGIQKNTIPNTYVPGRNTIFVAIGLSLAEARGANRIALGINAMDYSGYPDCRPDYLKAYQELANLSSRVGREGKGI
KLWAPLLDWEKTKIFEEALRLKIPIEKTWSCYQGESKPCGRCDSCRIRDKALKEIGREDLCSQNI

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=213, Percent_Identity=32.3943661971831, Blast_Score=114, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_PROM1 (A2C5G1)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001015985.1
- ProteinModelPortal:   A2C5G1
- SMR:   A2C5G1
- STRING:   A2C5G1
- GeneID:   4779781
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_21651
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- ProtClustDB:   CLSK922374
- BioCyc:   PMAR167555:NATL1_21651-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 24665; Mature: 24665

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEQTTIALLSGGIDSATAACIAMEAGQKVIGLSFDYGQRHLKELQAAADLAKNLNLEDH
CCCCCEEHHHHCCCCHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCE
ITIKIDLSSWGGSSLTDTSQAIPTKGIQKNTIPNTYVPGRNTIFVAIGLSLAEARGANRI
EEEEEEECCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHCCCCCEE
ALGINAMDYSGYPDCRPDYLKAYQELANLSSRVGREGKGIKLWAPLLDWEKTKIFEEALR
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHH
LKIPIEKTWSCYQGESKPCGRCDSCRIRDKALKEIGREDLCSQNI
EECCHHHCCHHHCCCCCCCCCCCCCCHHHHHHHHHCHHHHHCCCC
>Mature Secondary Structure
MIEQTTIALLSGGIDSATAACIAMEAGQKVIGLSFDYGQRHLKELQAAADLAKNLNLEDH
CCCCCEEHHHHCCCCHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCE
ITIKIDLSSWGGSSLTDTSQAIPTKGIQKNTIPNTYVPGRNTIFVAIGLSLAEARGANRI
EEEEEEECCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHCCCCCEE
ALGINAMDYSGYPDCRPDYLKAYQELANLSSRVGREGKGIKLWAPLLDWEKTKIFEEALR
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHH
LKIPIEKTWSCYQGESKPCGRCDSCRIRDKALKEIGREDLCSQNI
EECCHHHCCHHHCCCCCCCCCCCCCCHHHHHHHHHCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA