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The map label for this gene is speD [H]

Identifier: 124026723

GI number: 124026723

Start: 1661265

End: 1661732

Strand: Reverse

Name: speD [H]

Synonym: NATL1_20181

Alternate gene names: 124026723

Gene position: 1661732-1661265 (Counterclockwise)

Preceding gene: 124026724

Following gene: 124026721

Centisome position: 89.11

GC content: 38.03

Gene sequence:

>468_bases
ATGGAACCTTTTTTTTCTGAATTGCATCCAAATCCTGGATGGGGTGACTCTTTCAAGTCAAAAGATATAGATACTATACA
ATTTAATTCTAGTGAGAATATTGGACGGCACTGCATACTTGAACTCTACCAATGTGATCACGCGAGACTTAATGATGAAG
CTTTTATAAGGACATCTATTACATCATCGGCCAAAATTGCTGGTGCAACACTCATGAATTTGGTGACACATAGCTTTAAA
CCTCAAGGAGTAACTGGACTAGCTTTATTGGCTGAATCTCATATTTCAATACATACATGGCCTGAGATTGGTTATGCAGC
TATTGATGTTTTCACTTGTGGTGACCATACGATGCCTGAAAAAGCTTGTAAGTTTCTTTTTAAAGATTTTTTGGCTCAGC
ACTTTGCTTTTAAAAATATCGAAAGAGAGATCCCTGCCGGAATCCAGGCTTTGCATCGTGAACCTTGA

Upstream 100 bases:

>100_bases
TCTTTTGAGGGTGAATGGGTACGAAACTCACAATTAATGGAATTGGATTCTTTTAGTTGAAACTATTGGTCAGTTATTGT
GGAAATGATTTTTGGATAAT

Downstream 100 bases:

>100_bases
CCACAATGAAAGATTAAAAATAAATCAATCATCTTTTCGACATAGGAGTTTATTGTCTAAGTAGTCTTTATATCTCTTGT
GAGTTTTCCACTAATCAAAC

Product: S-adenosylmethionine decarboxylase proenzyme

Products: NA

Alternate protein names: AdoMetDC; SAMDC [H]

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MEPFFSELHPNPGWGDSFKSKDIDTIQFNSSENIGRHCILELYQCDHARLNDEAFIRTSITSSAKIAGATLMNLVTHSFK
PQGVTGLALLAESHISIHTWPEIGYAAIDVFTCGDHTMPEKACKFLFKDFLAQHFAFKNIEREIPAGIQALHREP

Sequences:

>Translated_155_residues
MEPFFSELHPNPGWGDSFKSKDIDTIQFNSSENIGRHCILELYQCDHARLNDEAFIRTSITSSAKIAGATLMNLVTHSFK
PQGVTGLALLAESHISIHTWPEIGYAAIDVFTCGDHTMPEKACKFLFKDFLAQHFAFKNIEREIPAGIQALHREP
>Mature_155_residues
MEPFFSELHPNPGWGDSFKSKDIDTIQFNSSENIGRHCILELYQCDHARLNDEAFIRTSITSSAKIAGATLMNLVTHSFK
PQGVTGLALLAESHISIHTWPEIGYAAIDVFTCGDHTMPEKACKFLFKDFLAQHFAFKNIEREIPAGIQALHREP

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine [H]

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716 [H]

Pfam domain/function: PF02675 AdoMet_dc [H]

EC number: =4.1.1.50 [H]

Molecular weight: Translated: 17389; Mature: 17389

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPFFSELHPNPGWGDSFKSKDIDTIQFNSSENIGRHCILELYQCDHARLNDEAFIRTSI
CCCCHHHCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEECC
TSSAKIAGATLMNLVTHSFKPQGVTGLALLAESHISIHTWPEIGYAAIDVFTCGDHTMPE
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEECCCCCEEEEEEEECCCCCCHH
KACKFLFKDFLAQHFAFKNIEREIPAGIQALHREP
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCC
>Mature Secondary Structure
MEPFFSELHPNPGWGDSFKSKDIDTIQFNSSENIGRHCILELYQCDHARLNDEAFIRTSI
CCCCHHHCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEECC
TSSAKIAGATLMNLVTHSFKPQGVTGLALLAESHISIHTWPEIGYAAIDVFTCGDHTMPE
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEECCCCCEEEEEEEECCCCCCHH
KACKFLFKDFLAQHFAFKNIEREIPAGIQALHREP
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917641 [H]