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The map label for this gene is btuR [C]

Identifier: 124026721

GI number: 124026721

Start: 1659082

End: 1660233

Strand: Reverse

Name: btuR [C]

Synonym: NATL1_20161

Alternate gene names: 124026721

Gene position: 1660233-1659082 (Counterclockwise)

Preceding gene: 124026723

Following gene: 124026718

Centisome position: 89.03

GC content: 42.71

Gene sequence:

>1152_bases
GTGGTTTCAAACGGTATAGGGATTACGACAGCATCGGAAAGCTTGGAACGTAGTCAAGGACAATTACATGTTTATGACGG
AGAGGGTAAAGGGAAGAGCCAGGCAGCCTTGGGGGTCGTTCTGAGGACCATAGGTCTAGGCATATGTGAGAAAAGACAAA
CAAGGGTATTACTTCTTAGATTCTTGAAAGGACCTGGTCGCTCGTATGACGAAGATGCCGCAATAGATGCTTTGCAGCAA
GGCTTCCCTCACTTGATTGATCAAGTGAGGACTGGCAGGGGAGAATTTTTTAGCGCCGATCAATCTACCAAATTTGATTA
TCAGGAAGCTCAAAGAGGTTGGGACATAGCCAAGGGGGCAATCGCTAGTGCCTTGTATTCAGTTGTTGTCCTCGACGAAT
TGAATCCTGTTCTGGATTTAGGATTATTGCCTGTTGAAGAAGTTGTTAAAACACTTAAGTCAAGACCAAACGGTATGGAA
ATTATCGTTACTGGAAGAGCTGCACCAAATCCTCTGATTAAAGTTGCGGAACTGCATTCTGAGATGAGAGCTCACAGACG
ACCTGAGATTAGTAACGATGAAATTCTTTTTGAAAATAATGTTGGTGGGATTGAAATATATACGGGTGAAGGAAAAGGCA
AATCAACCAGTGCGTTGGGTAAAGCTTTACAAGCTATCGGTAGAGGAATAAGTCAGGACAAAAGTCATCGTGTTTTGATT
TTGCAATGGCTGAAGGGTGGTAGTGGTTACACAGAGGATGCCGCTATTGCGGCTCTTCGAGAAAGTTATCCTCATTTAGT
AGACCATCTTCGATCTGGTAGAGATGCGATTGTTTGGAGGGGCCAGCAAAAGCCCATTGACTATGTAGAGGCTGAAAGAG
CATGGGAAATTGCAAGGGCAGCTATTTCAAGTGGTCTTTATAAGACTGTGATTTTGGATGAGTTAAATCCAACCGTTGAT
TTGGAACTCCTCCCAGTTGAGCCTATTGTTCAAACATTGCTTCGTAAACCTTCCGAAACCGAGGTGATTATTACAGGAAG
ATGCAAAAACCAACCTATATATTTTGATTTAGCAAGTGTTCATTCTGAGATGGTGTGTCACAAGCACTATGCTGAAAAAG
GAGTTGATTTAAAAAGGGGAGTTGATTATTAG

Upstream 100 bases:

>100_bases
GACTCTTAGTCTCCTTCATCTGTGTATGTATTTTGCATATTCTATGACGTCTATTGTATAAGAAGTTAGGTTGCATACAT
AAGAAGCAGAATTATCGATT

Downstream 100 bases:

>100_bases
TTTTAATTAATTTTTTTCGCTATTCCACGCATCAATACCTCCAAGAATATTAATACCTCTAATTCCAAATTTGTTTAAAT
GCTTTAATGCAAGCAATGAT

Product: hypothetical protein

Products: Adenosylcobalamin; Phosphate; Diphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MVSNGIGITTASESLERSQGQLHVYDGEGKGKSQAALGVVLRTIGLGICEKRQTRVLLLRFLKGPGRSYDEDAAIDALQQ
GFPHLIDQVRTGRGEFFSADQSTKFDYQEAQRGWDIAKGAIASALYSVVVLDELNPVLDLGLLPVEEVVKTLKSRPNGME
IIVTGRAAPNPLIKVAELHSEMRAHRRPEISNDEILFENNVGGIEIYTGEGKGKSTSALGKALQAIGRGISQDKSHRVLI
LQWLKGGSGYTEDAAIAALRESYPHLVDHLRSGRDAIVWRGQQKPIDYVEAERAWEIARAAISSGLYKTVILDELNPTVD
LELLPVEPIVQTLLRKPSETEVIITGRCKNQPIYFDLASVHSEMVCHKHYAEKGVDLKRGVDY

Sequences:

>Translated_383_residues
MVSNGIGITTASESLERSQGQLHVYDGEGKGKSQAALGVVLRTIGLGICEKRQTRVLLLRFLKGPGRSYDEDAAIDALQQ
GFPHLIDQVRTGRGEFFSADQSTKFDYQEAQRGWDIAKGAIASALYSVVVLDELNPVLDLGLLPVEEVVKTLKSRPNGME
IIVTGRAAPNPLIKVAELHSEMRAHRRPEISNDEILFENNVGGIEIYTGEGKGKSTSALGKALQAIGRGISQDKSHRVLI
LQWLKGGSGYTEDAAIAALRESYPHLVDHLRSGRDAIVWRGQQKPIDYVEAERAWEIARAAISSGLYKTVILDELNPTVD
LELLPVEPIVQTLLRKPSETEVIITGRCKNQPIYFDLASVHSEMVCHKHYAEKGVDLKRGVDY
>Mature_383_residues
MVSNGIGITTASESLERSQGQLHVYDGEGKGKSQAALGVVLRTIGLGICEKRQTRVLLLRFLKGPGRSYDEDAAIDALQQ
GFPHLIDQVRTGRGEFFSADQSTKFDYQEAQRGWDIAKGAIASALYSVVVLDELNPVLDLGLLPVEEVVKTLKSRPNGME
IIVTGRAAPNPLIKVAELHSEMRAHRRPEISNDEILFENNVGGIEIYTGEGKGKSTSALGKALQAIGRGISQDKSHRVLI
LQWLKGGSGYTEDAAIAALRESYPHLVDHLRSGRDAIVWRGQQKPIDYVEAERAWEIARAAISSGLYKTVILDELNPTVD
LELLPVEPIVQTLLRKPSETEVIITGRCKNQPIYFDLASVHSEMVCHKHYAEKGVDLKRGVDY

Specific function: Required For Both De Novo Synthesis Of The Corrin Ring For The Assimilation Of Exogenous Corrinoids. Participates In The Adenosylation Of A Variety Of Incomplete And Complete Corrinoids (By Similarity). [C]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787525, Length=186, Percent_Identity=31.7204301075269, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: 2.5.1.17 [C]

Molecular weight: Translated: 42128; Mature: 42128

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSNGIGITTASESLERSQGQLHVYDGEGKGKSQAALGVVLRTIGLGICEKRQTRVLLLR
CCCCCCCCEECHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHCCHHHCHHHHHHHHHH
FLKGPGRSYDEDAAIDALQQGFPHLIDQVRTGRGEFFSADQSTKFDYQEAQRGWDIAKGA
HHCCCCCCCCHHHHHHHHHHCHHHHHHHHHCCCCCEECCCCCCCCCHHHHHCCHHHHHHH
IASALYSVVVLDELNPVLDLGLLPVEEVVKTLKSRPNGMEIIVTGRAAPNPLIKVAELHS
HHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHH
EMRAHRRPEISNDEILFENNVGGIEIYTGEGKGKSTSALGKALQAIGRGISQDKSHRVLI
HHHHHCCCCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEE
LQWLKGGSGYTEDAAIAALRESYPHLVDHLRSGRDAIVWRGQQKPIDYVEAERAWEIARA
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHH
AISSGLYKTVILDELNPTVDLELLPVEPIVQTLLRKPSETEVIITGRCKNQPIYFDLASV
HHHCCCCEEEEECCCCCCEEEEEECHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEHHHH
HSEMVCHKHYAEKGVDLKRGVDY
HHHHHHHHHHHHCCCCHHCCCCC
>Mature Secondary Structure
MVSNGIGITTASESLERSQGQLHVYDGEGKGKSQAALGVVLRTIGLGICEKRQTRVLLLR
CCCCCCCCEECHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHCCHHHCHHHHHHHHHH
FLKGPGRSYDEDAAIDALQQGFPHLIDQVRTGRGEFFSADQSTKFDYQEAQRGWDIAKGA
HHCCCCCCCCHHHHHHHHHHCHHHHHHHHHCCCCCEECCCCCCCCCHHHHHCCHHHHHHH
IASALYSVVVLDELNPVLDLGLLPVEEVVKTLKSRPNGMEIIVTGRAAPNPLIKVAELHS
HHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHH
EMRAHRRPEISNDEILFENNVGGIEIYTGEGKGKSTSALGKALQAIGRGISQDKSHRVLI
HHHHHCCCCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEE
LQWLKGGSGYTEDAAIAALRESYPHLVDHLRSGRDAIVWRGQQKPIDYVEAERAWEIARA
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHH
AISSGLYKTVILDELNPTVDLELLPVEPIVQTLLRKPSETEVIITGRCKNQPIYFDLASV
HHHCCCCEEEEECCCCCCEEEEEECHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEHHHH
HSEMVCHKHYAEKGVDLKRGVDY
HHHHHHHHHHHHCCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; Cob(I)alamin; H2O [C]

Specific reaction: ATP + Cob(I)alamin + H2O <==> Adenosylcobalamin + Phosphate + Diphosphate [C]

General reaction: Adenosyl group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840; 7883709 [H]