Click here to switch to the map view.

The map label for this gene is engD [H]

Identifier: 124026292

GI number: 124026292

Start: 1292899

End: 1293990

Strand: Reverse

Name: engD [H]

Synonym: NATL1_15861

Alternate gene names: 124026292

Gene position: 1293990-1292899 (Counterclockwise)

Preceding gene: 124026296

Following gene: 124026291

Centisome position: 69.39

GC content: 36.26

Gene sequence:

>1092_bases
ATGCTTAAGGCCGGAATTGTTGGACTCCCTAATGTTGGGAAGTCCACCTTGTTCAATGCTCTTGTTGCGAATGCTCAAGC
TCAAGCAGCAAACTTTCCATTTTGTACGATTGAACCCAATGTAGGCTCTGTTTCAGTCCCTGACCAACGTTTGAATTTGC
TTGGTGAACTTAGTAATAGTAAGCAAATTATTCCAACGAGAATGGAGTTTGTTGATATTGCTGGTCTTGTTAAGGGAGCA
AGTAAAGGGGAGGGACTGGGTAACAAGTTTTTAGCAAATATAAGGGAAGTGGATGCAATAGTTCATGTGATTAGATGTTT
TAGAGATGATGATGTTATTCATGTTTCTGGATCAGTAGACCCATCAAGAGATATTGAGATAATAAATTTAGAATTAGCAT
TGTCTGATTTAAATCAAATAGAAAAACGTAGAACTCGATTAAAAAAACAAATAAGCACTATTAAGGAAGCAAAGTTAGAA
GATGATGTATTGGAAAAATTAAGCGAGGCTCTAGAAAATGAAAATGCAGTTAGGAGTGTTTCCTTAACTGATGAAGAAAA
GAAATTAATTAAACCATTAGGCTTATTAACTGAAAAACCAATTATTTATGCAACTAATCTTGGGGAAGATGAACTTGCGA
AGGGTAATTCCTTTTCAGATGAAGTAAATACACTCGCAACGAAAGAAGGGTCTGAATGTGTGAAGATTTCAGCGCAAGTT
GAAGCTGAGTTAATTGAATTGGGGGAGGAGGAAAGAGATGATTATCTAAATGGTTTAGGAGTTGAAGAAGGAGGCTTAAT
TAGTCTTATTAAAGCTACATATCGATTGTTGGGTTTAAGCACTTATTTCACTACTGGAGAAAAAGAAACTAAAGCTTGGA
CTATTTCTGATGGGATGACAGCTCCTCAAGCTGCCGGGGTAATACATACAGATTTTGAAAAGGGATTTATTCGAGCTCAA
ACAATCTCATACAAAAAACTACTTGAAGCAGGATCTTTAGTGGAAGCTCGAAACAAAGGTTGGCTTAGAAGTGAAGGTAA
AGAATATGTAGTTAATGAAGGAGACGTTATGGAGTTTTTATTCAACGTCTAA

Upstream 100 bases:

>100_bases
TTCCTTAAGAGATTTATAACAATATTTTCGCTGTTAATGGGCACGATTGGGTTTAATTTAGTCAGATTAATCAGCTGGGT
TCCTCTAAAGAACCATTTCA

Downstream 100 bases:

>100_bases
AAAGTCAGTGATACCAAGGGTTCTCAGGGGTTAGACTAAGGTTTGGTCTAACCATTTGGTCTAACTTTTTGAGACATGAA
AACTGGTTTTTGAGACAGGA

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MLKAGIVGLPNVGKSTLFNALVANAQAQAANFPFCTIEPNVGSVSVPDQRLNLLGELSNSKQIIPTRMEFVDIAGLVKGA
SKGEGLGNKFLANIREVDAIVHVIRCFRDDDVIHVSGSVDPSRDIEIINLELALSDLNQIEKRRTRLKKQISTIKEAKLE
DDVLEKLSEALENENAVRSVSLTDEEKKLIKPLGLLTEKPIIYATNLGEDELAKGNSFSDEVNTLATKEGSECVKISAQV
EAELIELGEEERDDYLNGLGVEEGGLISLIKATYRLLGLSTYFTTGEKETKAWTISDGMTAPQAAGVIHTDFEKGFIRAQ
TISYKKLLEAGSLVEARNKGWLRSEGKEYVVNEGDVMEFLFNV

Sequences:

>Translated_363_residues
MLKAGIVGLPNVGKSTLFNALVANAQAQAANFPFCTIEPNVGSVSVPDQRLNLLGELSNSKQIIPTRMEFVDIAGLVKGA
SKGEGLGNKFLANIREVDAIVHVIRCFRDDDVIHVSGSVDPSRDIEIINLELALSDLNQIEKRRTRLKKQISTIKEAKLE
DDVLEKLSEALENENAVRSVSLTDEEKKLIKPLGLLTEKPIIYATNLGEDELAKGNSFSDEVNTLATKEGSECVKISAQV
EAELIELGEEERDDYLNGLGVEEGGLISLIKATYRLLGLSTYFTTGEKETKAWTISDGMTAPQAAGVIHTDFEKGFIRAQ
TISYKKLLEAGSLVEARNKGWLRSEGKEYVVNEGDVMEFLFNV
>Mature_363_residues
MLKAGIVGLPNVGKSTLFNALVANAQAQAANFPFCTIEPNVGSVSVPDQRLNLLGELSNSKQIIPTRMEFVDIAGLVKGA
SKGEGLGNKFLANIREVDAIVHVIRCFRDDDVIHVSGSVDPSRDIEIINLELALSDLNQIEKRRTRLKKQISTIKEAKLE
DDVLEKLSEALENENAVRSVSLTDEEKKLIKPLGLLTEKPIIYATNLGEDELAKGNSFSDEVNTLATKEGSECVKISAQV
EAELIELGEEERDDYLNGLGVEEGGLISLIKATYRLLGLSTYFTTGEKETKAWTISDGMTAPQAAGVIHTDFEKGFIRAQ
TISYKKLLEAGSLVEARNKGWLRSEGKEYVVNEGDVMEFLFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=373, Percent_Identity=43.6997319034853, Blast_Score=284, Evalue=1e-76,
Organism=Homo sapiens, GI58761502, Length=213, Percent_Identity=37.0892018779343, Blast_Score=128, Evalue=1e-29,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=56.7493112947658, Blast_Score=402, Evalue=1e-113,
Organism=Escherichia coli, GI1789574, Length=177, Percent_Identity=28.8135593220339, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=42.6229508196721, Blast_Score=282, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6319499, Length=368, Percent_Identity=39.945652173913, Blast_Score=239, Evalue=5e-64,
Organism=Saccharomyces cerevisiae, GI6321773, Length=380, Percent_Identity=34.4736842105263, Blast_Score=211, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6321649, Length=174, Percent_Identity=35.0574712643678, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24640873, Length=369, Percent_Identity=42.0054200542005, Blast_Score=263, Evalue=1e-70,
Organism=Drosophila melanogaster, GI24640877, Length=369, Percent_Identity=42.0054200542005, Blast_Score=263, Evalue=1e-70,
Organism=Drosophila melanogaster, GI24640875, Length=369, Percent_Identity=42.0054200542005, Blast_Score=263, Evalue=1e-70,
Organism=Drosophila melanogaster, GI24640879, Length=327, Percent_Identity=39.1437308868502, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24585318, Length=142, Percent_Identity=33.0985915492958, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39744; Mature: 39744

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKAGIVGLPNVGKSTLFNALVANAQAQAANFPFCTIEPNVGSVSVPDQRLNLLGELSNS
CCCCCCCCCCCCCHHHHHHHHHHCCHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHCCCC
KQIIPTRMEFVDIAGLVKGASKGEGLGNKFLANIREVDAIVHVIRCFRDDDVIHVSGSVD
CCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PSRDIEIINLELALSDLNQIEKRRTRLKKQISTIKEAKLEDDVLEKLSEALENENAVRSV
CCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEE
SLTDEEKKLIKPLGLLTEKPIIYATNLGEDELAKGNSFSDEVNTLATKEGSECVKISAQV
ECCCHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCCCHHHHHHHHCCCCCCEEEEHHHH
EAELIELGEEERDDYLNGLGVEEGGLISLIKATYRLLGLSTYFTTGEKETKAWTISDGMT
HHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCEEEECCCCC
APQAAGVIHTDFEKGFIRAQTISYKKLLEAGSLVEARNKGWLRSEGKEYVVNEGDVMEFL
CCCCCCCEEECCCCCEEEEHHHHHHHHHHCCCHHHHHCCCCCCCCCCEEEECCCHHHHHH
FNV
HCC
>Mature Secondary Structure
MLKAGIVGLPNVGKSTLFNALVANAQAQAANFPFCTIEPNVGSVSVPDQRLNLLGELSNS
CCCCCCCCCCCCCHHHHHHHHHHCCHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHCCCC
KQIIPTRMEFVDIAGLVKGASKGEGLGNKFLANIREVDAIVHVIRCFRDDDVIHVSGSVD
CCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PSRDIEIINLELALSDLNQIEKRRTRLKKQISTIKEAKLEDDVLEKLSEALENENAVRSV
CCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEE
SLTDEEKKLIKPLGLLTEKPIIYATNLGEDELAKGNSFSDEVNTLATKEGSECVKISAQV
ECCCHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCCCHHHHHHHHCCCCCCEEEEHHHH
EAELIELGEEERDDYLNGLGVEEGGLISLIKATYRLLGLSTYFTTGEKETKAWTISDGMT
HHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCEEEECCCCC
APQAAGVIHTDFEKGFIRAQTISYKKLLEAGSLVEARNKGWLRSEGKEYVVNEGDVMEFL
CCCCCCCEEECCCCCEEEEHHHHHHHHHHCCCHHHHHCCCCCCCCCCEEEECCCHHHHHH
FNV
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]