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The map label for this gene is nagA [H]

Identifier: 124024955

GI number: 124024955

Start: 223118

End: 224278

Strand: Direct

Name: nagA [H]

Synonym: NATL1_02421

Alternate gene names: 124024955

Gene position: 223118-224278 (Clockwise)

Preceding gene: 124024953

Following gene: 124024956

Centisome position: 11.97

GC content: 34.97

Gene sequence:

>1161_bases
ATGAGAAAAATTACAAACATTAAAGTACCTCAACCAGAGAAAAGCGAAGATGAAAAGAATTTATTTTCACTAGTTTTAGA
TGAACATGGAATTATTCTTTCTATTGATAAAACTTGCAAGAAGGAATCAAGTTATGACGAAGATTGGCATGGAGATTGGC
TAAGTCCTAGAGCCATTGATCTTCAAATGAATGGAGGTTTAGGGATCTCATTTACAGATTTAAATTTTAATAAAATACCT
AAATTATTAACATTGCTTGATCAACTTTGGCTAGATGGAGTTGAAGGAATTTGTCCAACTTTTGTTAGTTGTTCTCTAGA
TCAATTTCAATTAGGAATGGAGGTCTTAAAGGAAACGAAAAAATATACTTCAACAAATCGATGTCGACTACTTGGCGCCC
ATATGGAAGGACCTTTTTTATGTGAGACATATTCTGGAGCACATGACACAGGAAGTATTTGTAGACCTAGTATTTCTGCC
TTAAATGAGAGAATAAAGGGATTTGAGGACGACATAGCACTAATGACATTGGCTCCAGAATTAAAAGGTTCTTTGGATGT
AATTTCTCGTCTAAGAGAATTAAATATCGTTGTCTCACTGGGACATTCTTCAGCTGATTTTGATTCAGCCATAAAAGCTT
TTAATAATGGTGTGAGCATGATTACGCATACTTTTAATGCAATGAAAGGTTTACATCATCGAGCTATTGGACCTATAGGA
GCGGCTGCAAGAAGAGACGATATTTTCCTAGGATTGATAGGTGATGGTGTTCATGTTCATTCAGATATGATTAGGCTTTT
AAAGATACTTGCACCAAAGCAAATTGTTTTAGTTAGCGATGCAATATCAGCTTATGGTTTAGGAGATGGATCGTTTAATT
GGGATAAACGCTTGATAACAGTAGAAAATGGTTTATGCAGACTTCCAAATGAAACAATTGCAGGATCCACTTTGCCTTTA
CTAGACGCATGCAAAAAAATAGCAAATTGGATTAATGATCCCTCTGCTGCTATTTGGATGGCAACACTTGCTCCACGTAT
GGTATTAAGTCAGAACAAAATGACTGCAAAATCTTTTTTTATTGGAAAGAATATTAAGTCTTTACTTAGATGGAAAATGA
ATTCTTGTAATCATCAGTTGTCTTGGCAGTTGGCTGCGTAA

Upstream 100 bases:

>100_bases
TATTAGCTTCAGTTAAAGACAATTGTCAATTTTATAAATCTCATTTTTATAATGCCAATTATTTAAGAATTCTGCATTAA
TTATTTTTAGTTTTTAAGAA

Downstream 100 bases:

>100_bases
GATTGGTAAGAGGTAATTATCTGATTAAATGACAACGCAAATTGAGAAAAATGAAAAGGCGGAAGTCACTGAATATTTTA
ATGGGACTGGGTTTGATAGA

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MRKITNIKVPQPEKSEDEKNLFSLVLDEHGIILSIDKTCKKESSYDEDWHGDWLSPRAIDLQMNGGLGISFTDLNFNKIP
KLLTLLDQLWLDGVEGICPTFVSCSLDQFQLGMEVLKETKKYTSTNRCRLLGAHMEGPFLCETYSGAHDTGSICRPSISA
LNERIKGFEDDIALMTLAPELKGSLDVISRLRELNIVVSLGHSSADFDSAIKAFNNGVSMITHTFNAMKGLHHRAIGPIG
AAARRDDIFLGLIGDGVHVHSDMIRLLKILAPKQIVLVSDAISAYGLGDGSFNWDKRLITVENGLCRLPNETIAGSTLPL
LDACKKIANWINDPSAAIWMATLAPRMVLSQNKMTAKSFFIGKNIKSLLRWKMNSCNHQLSWQLAA

Sequences:

>Translated_386_residues
MRKITNIKVPQPEKSEDEKNLFSLVLDEHGIILSIDKTCKKESSYDEDWHGDWLSPRAIDLQMNGGLGISFTDLNFNKIP
KLLTLLDQLWLDGVEGICPTFVSCSLDQFQLGMEVLKETKKYTSTNRCRLLGAHMEGPFLCETYSGAHDTGSICRPSISA
LNERIKGFEDDIALMTLAPELKGSLDVISRLRELNIVVSLGHSSADFDSAIKAFNNGVSMITHTFNAMKGLHHRAIGPIG
AAARRDDIFLGLIGDGVHVHSDMIRLLKILAPKQIVLVSDAISAYGLGDGSFNWDKRLITVENGLCRLPNETIAGSTLPL
LDACKKIANWINDPSAAIWMATLAPRMVLSQNKMTAKSFFIGKNIKSLLRWKMNSCNHQLSWQLAA
>Mature_386_residues
MRKITNIKVPQPEKSEDEKNLFSLVLDEHGIILSIDKTCKKESSYDEDWHGDWLSPRAIDLQMNGGLGISFTDLNFNKIP
KLLTLLDQLWLDGVEGICPTFVSCSLDQFQLGMEVLKETKKYTSTNRCRLLGAHMEGPFLCETYSGAHDTGSICRPSISA
LNERIKGFEDDIALMTLAPELKGSLDVISRLRELNIVVSLGHSSADFDSAIKAFNNGVSMITHTFNAMKGLHHRAIGPIG
AAARRDDIFLGLIGDGVHVHSDMIRLLKILAPKQIVLVSDAISAYGLGDGSFNWDKRLITVENGLCRLPNETIAGSTLPL
LDACKKIANWINDPSAAIWMATLAPRMVLSQNKMTAKSFFIGKNIKSLLRWKMNSCNHQLSWQLAA

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=274, Percent_Identity=32.4817518248175, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI224922791, Length=273, Percent_Identity=32.6007326007326, Blast_Score=135, Evalue=4e-32,
Organism=Escherichia coli, GI1786892, Length=337, Percent_Identity=30.8605341246291, Blast_Score=139, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17553768, Length=315, Percent_Identity=32.6984126984127, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI19920392, Length=351, Percent_Identity=32.4786324786325, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI281361140, Length=364, Percent_Identity=31.043956043956, Blast_Score=147, Evalue=8e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 42709; Mature: 42709

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKITNIKVPQPEKSEDEKNLFSLVLDEHGIILSIDKTCKKESSYDEDWHGDWLSPRAID
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECHHHCCCCCCCCCCCCCCCCCEEEE
LQMNGGLGISFTDLNFNKIPKLLTLLDQLWLDGVEGICPTFVSCSLDQFQLGMEVLKETK
EEECCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHH
KYTSTNRCRLLGAHMEGPFLCETYSGAHDTGSICRPSISALNERIKGFEDDIALMTLAPE
HHCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECHH
LKGSLDVISRLRELNIVVSLGHSSADFDSAIKAFNNGVSMITHTFNAMKGLHHRAIGPIG
HCCHHHHHHHHHHCEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
AAARRDDIFLGLIGDGVHVHSDMIRLLKILAPKQIVLVSDAISAYGLGDGSFNWDKRLIT
CCCCCCCEEEEEECCCEEHHHHHHHHHHHHCCCEEEEEECCHHHCCCCCCCCCCCCEEEE
VENGLCRLPNETIAGSTLPLLDACKKIANWINDPSAAIWMATLAPRMVLSQNKMTAKSFF
ECCCCEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
IGKNIKSLLRWKMNSCNHQLSWQLAA
HHHHHHHHHHHHHHCCCCEEEEEECC
>Mature Secondary Structure
MRKITNIKVPQPEKSEDEKNLFSLVLDEHGIILSIDKTCKKESSYDEDWHGDWLSPRAID
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECHHHCCCCCCCCCCCCCCCCCEEEE
LQMNGGLGISFTDLNFNKIPKLLTLLDQLWLDGVEGICPTFVSCSLDQFQLGMEVLKETK
EEECCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHH
KYTSTNRCRLLGAHMEGPFLCETYSGAHDTGSICRPSISALNERIKGFEDDIALMTLAPE
HHCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECHH
LKGSLDVISRLRELNIVVSLGHSSADFDSAIKAFNNGVSMITHTFNAMKGLHHRAIGPIG
HCCHHHHHHHHHHCEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
AAARRDDIFLGLIGDGVHVHSDMIRLLKILAPKQIVLVSDAISAYGLGDGSFNWDKRLIT
CCCCCCCEEEEEECCCEEHHHHHHHHHHHHCCCEEEEEECCHHHCCCCCCCCCCCCEEEE
VENGLCRLPNETIAGSTLPLLDACKKIANWINDPSAAIWMATLAPRMVLSQNKMTAKSFF
ECCCCEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
IGKNIKSLLRWKMNSCNHQLSWQLAA
HHHHHHHHHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969210 [H]