Click here to switch to the map view.

The map label for this gene is cysC [H]

Identifier: 124024953

GI number: 124024953

Start: 221840

End: 222478

Strand: Direct

Name: cysC [H]

Synonym: NATL1_02401

Alternate gene names: 124024953

Gene position: 221840-222478 (Clockwise)

Preceding gene: 124024952

Following gene: 124024955

Centisome position: 11.9

GC content: 35.84

Gene sequence:

>639_bases
ATGGAACAAAACTCTAAAAGTCCTCTATCAAAAGCCACCAATATAGTTTGGCACCAATCTTCAGTTGATAGAGAAGCTAG
ATCTCAGCAAAGAGGACATCGCAGCGCAATACTTTGGTTTACAGGTCTATCTGGTTCTGGAAAAAGCACACTAGCCAATG
CAGTAAATGTAGCTCTACACAAAGATGGTTATTCAACTTATGTTTTAGATGGTGACAACATCAGACATGGTTTATGCAAA
GACTTGGGATTTTCTGATCTTGATAGGGAAGAAAATATCAGAAGAATTGGCGAAGTCTCTAAACTATTTCTTGACGCTGG
AATCATTGTTTTAACTGCATTCGTATCTCCATTTAGAGTCGATCGCGATAATGCAAGATCTTTAGTTGGAGAGAATGATT
TTATAGAAATATATTGTTCAGCTGATCTAGGGGTTTGTGAAACAAGAGATACAAAAGGGCTTTATGCCAAGGCAAGAAAC
GGAGACATCAAAGATTTTACTGGAATCTCAAGTCCTTATGAAGAACCTCAGTCTCCAGAATTGAAAATTGATACTGGAAA
TCTAGAGATTGATCAATGTGTAGATATAGTTACTAATTTGCTTGTTGAAAGAAAGATTATTTCAAAAATTTCTAAGTAA

Upstream 100 bases:

>100_bases
AATTTTCTTTTAAAGGAGGGTTTTAGGCCAAAACAAAGTGGAGGTTAACAATAAACTGTGTCGATCAACATGGAGAATAG
TAAACAATTAGTCTGCATTC

Downstream 100 bases:

>100_bases
ATTAGTAAGTTAATGGAAAATTAATTACATTTTTTCTAGATAAGTTATAGCTCCAATCTCTTTAAGTGTGTGATCTTTTT
TAACGACAAGGTCGTGCAGC

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MEQNSKSPLSKATNIVWHQSSVDREARSQQRGHRSAILWFTGLSGSGKSTLANAVNVALHKDGYSTYVLDGDNIRHGLCK
DLGFSDLDREENIRRIGEVSKLFLDAGIIVLTAFVSPFRVDRDNARSLVGENDFIEIYCSADLGVCETRDTKGLYAKARN
GDIKDFTGISSPYEEPQSPELKIDTGNLEIDQCVDIVTNLLVERKIISKISK

Sequences:

>Translated_212_residues
MEQNSKSPLSKATNIVWHQSSVDREARSQQRGHRSAILWFTGLSGSGKSTLANAVNVALHKDGYSTYVLDGDNIRHGLCK
DLGFSDLDREENIRRIGEVSKLFLDAGIIVLTAFVSPFRVDRDNARSLVGENDFIEIYCSADLGVCETRDTKGLYAKARN
GDIKDFTGISSPYEEPQSPELKIDTGNLEIDQCVDIVTNLLVERKIISKISK
>Mature_212_residues
MEQNSKSPLSKATNIVWHQSSVDREARSQQRGHRSAILWFTGLSGSGKSTLANAVNVALHKDGYSTYVLDGDNIRHGLCK
DLGFSDLDREENIRRIGEVSKLFLDAGIIVLTAFVSPFRVDRDNARSLVGENDFIEIYCSADLGVCETRDTKGLYAKARN
GDIKDFTGISSPYEEPQSPELKIDTGNLEIDQCVDIVTNLLVERKIISKISK

Specific function: Catalyzes the synthesis of activated sulfate [H]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI46094058, Length=206, Percent_Identity=48.5436893203884, Blast_Score=200, Evalue=9e-52,
Organism=Homo sapiens, GI34447231, Length=205, Percent_Identity=47.8048780487805, Blast_Score=193, Evalue=9e-50,
Organism=Homo sapiens, GI62912492, Length=205, Percent_Identity=47.8048780487805, Blast_Score=193, Evalue=1e-49,
Organism=Escherichia coli, GI1789107, Length=194, Percent_Identity=54.639175257732, Blast_Score=228, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI17542422, Length=205, Percent_Identity=48.780487804878, Blast_Score=196, Evalue=8e-51,
Organism=Saccharomyces cerevisiae, GI6322852, Length=200, Percent_Identity=53, Blast_Score=203, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24667032, Length=214, Percent_Identity=45.7943925233645, Blast_Score=187, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24667028, Length=214, Percent_Identity=45.7943925233645, Blast_Score=187, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24667036, Length=214, Percent_Identity=45.7943925233645, Blast_Score=187, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24667040, Length=215, Percent_Identity=45.5813953488372, Blast_Score=186, Evalue=8e-48,
Organism=Drosophila melanogaster, GI116007838, Length=207, Percent_Identity=46.8599033816425, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24667044, Length=207, Percent_Identity=46.8599033816425, Blast_Score=186, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891 [H]

Pfam domain/function: PF01583 APS_kinase [H]

EC number: =2.7.1.25 [H]

Molecular weight: Translated: 23509; Mature: 23509

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQNSKSPLSKATNIVWHQSSVDREARSQQRGHRSAILWFTGLSGSGKSTLANAVNVALH
CCCCCCCCHHHHHHEEECCCHHCHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHEEEE
KDGYSTYVLDGDNIRHGLCKDLGFSDLDREENIRRIGEVSKLFLDAGIIVLTAFVSPFRV
CCCCEEEEECCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DRDNARSLVGENDFIEIYCSADLGVCETRDTKGLYAKARNGDIKDFTGISSPYEEPQSPE
CCHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCC
LKIDTGNLEIDQCVDIVTNLLVERKIISKISK
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEQNSKSPLSKATNIVWHQSSVDREARSQQRGHRSAILWFTGLSGSGKSTLANAVNVALH
CCCCCCCCHHHHHHEEECCCHHCHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHEEEE
KDGYSTYVLDGDNIRHGLCKDLGFSDLDREENIRRIGEVSKLFLDAGIIVLTAFVSPFRV
CCCCEEEEECCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DRDNARSLVGENDFIEIYCSADLGVCETRDTKGLYAKARNGDIKDFTGISSPYEEPQSPE
CCHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCC
LKIDTGNLEIDQCVDIVTNLLVERKIISKISK
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917486 [H]