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The map label for this gene is yebU [C]

Identifier: 124028405

GI number: 124028405

Start: 1569293

End: 1570315

Strand: Reverse

Name: yebU [C]

Synonym: Hbut_1559

Alternate gene names: 124028405

Gene position: 1570315-1569293 (Counterclockwise)

Preceding gene: 124028408

Following gene: 124028404

Centisome position: 94.19

GC content: 51.12

Gene sequence:

>1023_bases
ATGAATATAGCTGCAGCTCTGAGAGAACTCAAGGAGGCATTTCACCGGCTGGAGGAGAAGTACGGAGACCTAGCTCAAAG
CCTAGTGGAGAAGTATCATAGTGTGCGTCTCCACAGAGACCAGGTGGTCAGATATCTAGAGCTGTTTGACACGGTCTCGG
AGGTCGAGAGGCTCCTGTCAACAGGCGAGGACAAGGTAATGAAAACCATAAGGGTTAACACTCTGCTCGCAGATCCGGAA
GAGGTGTCCGAGAGGCTGGAAGCAAAGGGATTTAGGCTGAGAAGACATCCATACATAGACTACGGTCTCGTAGTCCTCGA
AGAACCAATACCCATTGGTGCAACCCACGAATACATGCTTGGCCTCTACACGGTTCAAGGGCCAGCATCGATGATGGTAG
TCCCAGCGCTGGATCCTCCAGGGAAGGGTAGGATAGCTGACATGTGTGCCGGGGCAGGTGTAAAGACTACGCAGATAGCC
CAGCATAGCCCACAAGCACACATTGTAGCACTAGATATAAACCGGAGAAAGCTCCTCGCACTCAAAAACAATGCTAGTAG
GCTAGCAGTCTTCAACATAGTTGCGCTAAACATGGATGCTCGCCGTCTACCACAACTAGGACGCTTCGACGCAATACTAC
TCGACGCGCCTTGTAGCGGCGAGGGTCTATTAGCATTCCAACGGGGGCGTTGGCCGAGAAGCTTCAACGATATAGCCTCT
AGGGTGGAACTCCAACTCCAACTCCTAAAAGCAGGTATAGAGGCACTAGCCGACAATGGCGTACTCGTATATGCAACCTG
TAGCATATCGGTTGAGGAAAATGAATACGTCGTCACAAGGATCCTTGAGGAGTACAGCAGTCTGGATCTCGAGGAACCAC
CGATAAAGGCTGGGTTACCCGGTAAGCAGAGCTACGCTGGCCTAAAATTAGACAGACGTGTATCAAGGTGCCGCCGCTTC
TACCCCCACATACACGGGACTGAGGGATTTACAATATGCAGGTTGGTGAAGAGAAAAAGCTAG

Upstream 100 bases:

>100_bases
CGCGATAAACCATAGAACCCGCTCACCCGGATTCGCTGGACACGCTGCCAGACAGGCTAAGCATATTGCGGCTAGGCCTG
GCAGCACGGAGAGGAAAGCC

Downstream 100 bases:

>100_bases
GAATGTGCAGTAGTGAGATACGAGACCTACTTAGAGGGCTTGTAGAGTGTATTGTAGGAGTAGACGTCCTAAAGCACTAC
AGCCTCCTATGCAAACACAG

Product: tRNA and rRNA cytosine-C5-methylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MNIAAALRELKEAFHRLEEKYGDLAQSLVEKYHSVRLHRDQVVRYLELFDTVSEVERLLSTGEDKVMKTIRVNTLLADPE
EVSERLEAKGFRLRRHPYIDYGLVVLEEPIPIGATHEYMLGLYTVQGPASMMVVPALDPPGKGRIADMCAGAGVKTTQIA
QHSPQAHIVALDINRRKLLALKNNASRLAVFNIVALNMDARRLPQLGRFDAILLDAPCSGEGLLAFQRGRWPRSFNDIAS
RVELQLQLLKAGIEALADNGVLVYATCSISVEENEYVVTRILEEYSSLDLEEPPIKAGLPGKQSYAGLKLDRRVSRCRRF
YPHIHGTEGFTICRLVKRKS

Sequences:

>Translated_340_residues
MNIAAALRELKEAFHRLEEKYGDLAQSLVEKYHSVRLHRDQVVRYLELFDTVSEVERLLSTGEDKVMKTIRVNTLLADPE
EVSERLEAKGFRLRRHPYIDYGLVVLEEPIPIGATHEYMLGLYTVQGPASMMVVPALDPPGKGRIADMCAGAGVKTTQIA
QHSPQAHIVALDINRRKLLALKNNASRLAVFNIVALNMDARRLPQLGRFDAILLDAPCSGEGLLAFQRGRWPRSFNDIAS
RVELQLQLLKAGIEALADNGVLVYATCSISVEENEYVVTRILEEYSSLDLEEPPIKAGLPGKQSYAGLKLDRRVSRCRRF
YPHIHGTEGFTICRLVKRKS
>Mature_340_residues
MNIAAALRELKEAFHRLEEKYGDLAQSLVEKYHSVRLHRDQVVRYLELFDTVSEVERLLSTGEDKVMKTIRVNTLLADPE
EVSERLEAKGFRLRRHPYIDYGLVVLEEPIPIGATHEYMLGLYTVQGPASMMVVPALDPPGKGRIADMCAGAGVKTTQIA
QHSPQAHIVALDINRRKLLALKNNASRLAVFNIVALNMDARRLPQLGRFDAILLDAPCSGEGLLAFQRGRWPRSFNDIAS
RVELQLQLLKAGIEALADNGVLVYATCSISVEENEYVVTRILEEYSSLDLEEPPIKAGLPGKQSYAGLKLDRRVSRCRRF
YPHIHGTEGFTICRLVKRKS

Specific function: May act as RNA methyltransferase [H]

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=320, Percent_Identity=34.375, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI76150623, Length=320, Percent_Identity=34.375, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI32698918, Length=234, Percent_Identity=32.9059829059829, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI301336155, Length=368, Percent_Identity=25.5434782608696, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI39995082, Length=256, Percent_Identity=28.90625, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI11545785, Length=175, Percent_Identity=27.4285714285714, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI87081985, Length=322, Percent_Identity=29.8136645962733, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI2367212, Length=230, Percent_Identity=35.2173913043478, Blast_Score=111, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17536757, Length=305, Percent_Identity=32.7868852459016, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI25143471, Length=183, Percent_Identity=27.3224043715847, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324268, Length=277, Percent_Identity=36.8231046931408, Blast_Score=162, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6319447, Length=267, Percent_Identity=27.7153558052434, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI22024126, Length=307, Percent_Identity=31.5960912052117, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI21355201, Length=202, Percent_Identity=29.7029702970297, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24668781, Length=205, Percent_Identity=31.219512195122, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356513, Length=205, Percent_Identity=31.219512195122, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR011023 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu [H]

EC number: NA

Molecular weight: Translated: 38157; Mature: 38157

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIAAALRELKEAFHRLEEKYGDLAQSLVEKYHSVRLHRDQVVRYLELFDTVSEVERLLS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGEDKVMKTIRVNTLLADPEEVSERLEAKGFRLRRHPYIDYGLVVLEEPIPIGATHEYML
CCHHHHHHHHHHHHEECCHHHHHHHHHHCCCEEECCCCCCCCEEEEECCCCCCCCHHHEE
GLYTVQGPASMMVVPALDPPGKGRIADMCAGAGVKTTQIAQHSPQAHIVALDINRRKLLA
EEEEECCCCCEEEEECCCCCCCCCHHHHHCCCCCCHHHHHCCCCCEEEEEEECCCEEEEE
LKNNASRLAVFNIVALNMDARRLPQLGRFDAILLDAPCSGEGLLAFQRGRWPRSFNDIAS
EECCCCEEEEEEEEEECCCHHHCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHH
RVELQLQLLKAGIEALADNGVLVYATCSISVEENEYVVTRILEEYSSLDLEEPPIKAGLP
HHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCC
GKQSYAGLKLDRRVSRCRRFYPHIHGTEGFTICRLVKRKS
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MNIAAALRELKEAFHRLEEKYGDLAQSLVEKYHSVRLHRDQVVRYLELFDTVSEVERLLS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGEDKVMKTIRVNTLLADPEEVSERLEAKGFRLRRHPYIDYGLVVLEEPIPIGATHEYML
CCHHHHHHHHHHHHEECCHHHHHHHHHHCCCEEECCCCCCCCEEEEECCCCCCCCHHHEE
GLYTVQGPASMMVVPALDPPGKGRIADMCAGAGVKTTQIAQHSPQAHIVALDINRRKLLA
EEEEECCCCCEEEEECCCCCCCCCHHHHHCCCCCCHHHHHCCCCCEEEEEEECCCEEEEE
LKNNASRLAVFNIVALNMDARRLPQLGRFDAILLDAPCSGEGLLAFQRGRWPRSFNDIAS
EECCCCEEEEEEEEEECCCHHHCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHH
RVELQLQLLKAGIEALADNGVLVYATCSISVEENEYVVTRILEEYSSLDLEEPPIKAGLP
HHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCC
GKQSYAGLKLDRRVSRCRRFYPHIHGTEGFTICRLVKRKS
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]