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The map label for this gene is engA [C]

Identifier: 124028408

GI number: 124028408

Start: 1572013

End: 1573140

Strand: Reverse

Name: engA [C]

Synonym: Hbut_1562

Alternate gene names: 124028408

Gene position: 1573140-1572013 (Counterclockwise)

Preceding gene: 124028409

Following gene: 124028405

Centisome position: 94.36

GC content: 51.15

Gene sequence:

>1128_bases
ATGGAGGCTAGGGAGCTACCCTGGTTGGCTAGGCAGCTAGAGGCCCAGAAGATAGTTGAGACTGTGAGAAGGCTGCGTGA
GGTGCACGTATACACAGCTGATGAGATAGTTAGGATAGTTGGCGAGAGATATCGACGAATTCGCCGGAGTAAGCCGGGGC
TACCTGGCAAGATAGAGTTTGAGATCAAGAGGCTCGAAGTAGTATTCAACGTGGCTTACAGCAGGCTCCAGGCTGCAGCA
AAGCTACCCACGACTAGGGAGATGAGTGAGTTTCACCGGGTACTCGTAGAGAGCTTTGTTGGCAGAGAGTACGACGAGGC
GCTACGCAGAATACGTAGAGCACTAAAGCTGGTCAAGAACTTCTGGGCAGAGTACAGGCTCCTAATAGCCTCAGCAGAGT
CTGCAGTTGAGGCGGCGAGACTACGTAAGGAGGGTAGCGGCAGAATACTATCAGTTGTTAGGAGGTTGCGGAAACACCTA
GAACTGGTAGAAAGGGTGCGTAGAGAGCTTCTAAAAACACATGTCGTCGCCGAGGGTTTGCCTGTGGTAGTTGTTGCTGG
AATACCTAGTGCAGGTAAGTCGACACTGGTGCGCAGGATATCAACAGCTGAACCCGAGATAGCATCATACCCCTTTACTA
CGAAGAGCATTATAGTTGGTAAGGCTCGCCACCAGGGCATGGTTTTCTACGTTGTTGATACGCCTGGAATCCTCGAGAGG
CCTCTCGAGCTACACAACGAGATCGAGAGGAAGGCACTTGCGGCGCTCAAAACACTTCCAGACATAGTACTTGTTCTCCT
TGATCCTTCACCCGAGAAGGTGCAAAGCCTTGAAAACCAAGAGAGGCTACTACGCAGTATATATGAGGGTATAGTGAAGC
CCCGGGAGGCAGGTCTAATTATAGCCGTAAATAAGGTTGATGCGTCAGCTAGAGAGGAAGTGGAGAAAGCTATAGAGATG
GCCTCATCGCTACTACGTGATGTAAACCAGTCCGTGCGGTGTGTCAACAAGCCGATACCGATATCTGCACTGCATGGGCA
AGGTGTAGGCGAGCTGCTAGATGTGGTTATTGAGTGTTTGAAGCGTAAAACGCCTTGGCTCTTCCCTGGAGCAGAGCCTA
GGAGCTAG

Upstream 100 bases:

>100_bases
ATGGGTCAGCCATCGCTATCTGAGGCATTAGCCTCAATGAGTATAGCCGCTAGCCTAACTGGTTAAGAGGGTGTGGCTGC
AGCTGCCCCTAGAGGGGAGT

Downstream 100 bases:

>100_bases
GCTTGTAGCAGATACCCTTCACCCTCAGCTTAAACTTCTCATTCAGCTTGCCACCTTCAATAAACTCCATCTCAGCTCCC
GGCACGAGCATCTTAACAAC

Product: GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MEARELPWLARQLEAQKIVETVRRLREVHVYTADEIVRIVGERYRRIRRSKPGLPGKIEFEIKRLEVVFNVAYSRLQAAA
KLPTTREMSEFHRVLVESFVGREYDEALRRIRRALKLVKNFWAEYRLLIASAESAVEAARLRKEGSGRILSVVRRLRKHL
ELVERVRRELLKTHVVAEGLPVVVVAGIPSAGKSTLVRRISTAEPEIASYPFTTKSIIVGKARHQGMVFYVVDTPGILER
PLELHNEIERKALAALKTLPDIVLVLLDPSPEKVQSLENQERLLRSIYEGIVKPREAGLIIAVNKVDASAREEVEKAIEM
ASSLLRDVNQSVRCVNKPIPISALHGQGVGELLDVVIECLKRKTPWLFPGAEPRS

Sequences:

>Translated_375_residues
MEARELPWLARQLEAQKIVETVRRLREVHVYTADEIVRIVGERYRRIRRSKPGLPGKIEFEIKRLEVVFNVAYSRLQAAA
KLPTTREMSEFHRVLVESFVGREYDEALRRIRRALKLVKNFWAEYRLLIASAESAVEAARLRKEGSGRILSVVRRLRKHL
ELVERVRRELLKTHVVAEGLPVVVVAGIPSAGKSTLVRRISTAEPEIASYPFTTKSIIVGKARHQGMVFYVVDTPGILER
PLELHNEIERKALAALKTLPDIVLVLLDPSPEKVQSLENQERLLRSIYEGIVKPREAGLIIAVNKVDASAREEVEKAIEM
ASSLLRDVNQSVRCVNKPIPISALHGQGVGELLDVVIECLKRKTPWLFPGAEPRS
>Mature_375_residues
MEARELPWLARQLEAQKIVETVRRLREVHVYTADEIVRIVGERYRRIRRSKPGLPGKIEFEIKRLEVVFNVAYSRLQAAA
KLPTTREMSEFHRVLVESFVGREYDEALRRIRRALKLVKNFWAEYRLLIASAESAVEAARLRKEGSGRILSVVRRLRKHL
ELVERVRRELLKTHVVAEGLPVVVVAGIPSAGKSTLVRRISTAEPEIASYPFTTKSIIVGKARHQGMVFYVVDTPGILER
PLELHNEIERKALAALKTLPDIVLVLLDPSPEKVQSLENQERLLRSIYEGIVKPREAGLIIAVNKVDASAREEVEKAIEM
ASSLLRDVNQSVRCVNKPIPISALHGQGVGELLDVVIECLKRKTPWLFPGAEPRS

Specific function: Gtpase Of Unknown Physiological Role. [C]

COG id: COG1084

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP1/OBG family. NOG subfamily [H]

Homologues:

Organism=Homo sapiens, GI55953087, Length=251, Percent_Identity=30.6772908366534, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI25145602, Length=264, Percent_Identity=29.9242424242424, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI25145600, Length=264, Percent_Identity=29.9242424242424, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6325164, Length=229, Percent_Identity=30.5676855895196, Blast_Score=119, Evalue=5e-28,
Organism=Drosophila melanogaster, GI19921908, Length=259, Percent_Identity=30.8880308880309, Blast_Score=125, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006073
- InterPro:   IPR010674
- InterPro:   IPR005225 [H]

Pfam domain/function: PF06858 NOG1 [H]

EC number: NA

Molecular weight: Translated: 42530; Mature: 42530

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEARELPWLARQLEAQKIVETVRRLREVHVYTADEIVRIVGERYRRIRRSKPGLPGKIEF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEH
EIKRLEVVFNVAYSRLQAAAKLPTTREMSEFHRVLVESFVGREYDEALRRIRRALKLVKN
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FWAEYRLLIASAESAVEAARLRKEGSGRILSVVRRLRKHLELVERVRRELLKTHVVAEGL
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PVVVVAGIPSAGKSTLVRRISTAEPEIASYPFTTKSIIVGKARHQGMVFYVVDTPGILER
CEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHEEECCCCCCEEEEEECCCCHHHH
PLELHNEIERKALAALKTLPDIVLVLLDPSPEKVQSLENQERLLRSIYEGIVKPREAGLI
HHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
IAVNKVDASAREEVEKAIEMASSLLRDVNQSVRCVNKPIPISALHGQGVGELLDVVIECL
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHH
KRKTPWLFPGAEPRS
HCCCCCCCCCCCCCC
>Mature Secondary Structure
MEARELPWLARQLEAQKIVETVRRLREVHVYTADEIVRIVGERYRRIRRSKPGLPGKIEF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEH
EIKRLEVVFNVAYSRLQAAAKLPTTREMSEFHRVLVESFVGREYDEALRRIRRALKLVKN
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FWAEYRLLIASAESAVEAARLRKEGSGRILSVVRRLRKHLELVERVRRELLKTHVVAEGL
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PVVVVAGIPSAGKSTLVRRISTAEPEIASYPFTTKSIIVGKARHQGMVFYVVDTPGILER
CEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHEEECCCCCCEEEEEECCCCHHHH
PLELHNEIERKALAALKTLPDIVLVLLDPSPEKVQSLENQERLLRSIYEGIVKPREAGLI
HHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
IAVNKVDASAREEVEKAIEMASSLLRDVNQSVRCVNKPIPISALHGQGVGELLDVVIECL
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHH
KRKTPWLFPGAEPRS
HCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]