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The map label for this gene is cysC [H]

Identifier: 124028214

GI number: 124028214

Start: 1355461

End: 1356042

Strand: Direct

Name: cysC [H]

Synonym: Hbut_1364

Alternate gene names: 124028214

Gene position: 1355461-1356042 (Clockwise)

Preceding gene: 124028210

Following gene: 124028222

Centisome position: 81.3

GC content: 59.28

Gene sequence:

>582_bases
TTGGAGCGCCATGGGAATGCTGGGCTGATATGCCTCAAACGCGGTATTGTAGCGTGGCTTACGGGGCTGCCGGGTAGCGG
CAAGACAACTATAGCCCGTCTCGCCGCGGAGAAGCTCCGCGAGATGGGGTATCGCGTCGAGCACCTTGACGGCGACTGGG
TAAGGAAGACCATCAACCCCGATGCGGGCTACACCAGGGAGGAGAGGCGCCGACACCTTCTACGGGTAGCGTGGATAGCC
AGGCTTCTGGCCCGGCACGGTGTTATAGTTCTCTGCAGCTTCGTCTCCCCATACCGTGACGTACGTAGGGAGGTGCGGGA
AATAGTCGAGGCGGAGGGTGTACCCTTCATAGAGGTCTACGTCAAGTGTCCAGTGGAGGAATGCATCAAGCGCGACCCGA
AGGGCCTCTATCGGAAGGCGCTGCAAGGCCTAATCAAGCACTTCACCGGGGTGAGCGACCCCTACGAGCCGCCGGAAAAC
CCGGACCTGGAGCTAGACACGGTAAGCAATACAGCTGAGGAAAACGCCGAGAAGCTTGTTGAAACGATACTTGCGAGACT
ACCCCGGGATAAGCCAGGCTAA

Upstream 100 bases:

>100_bases
ACCGGGTTGAGGCTAGGCTAGCACGAGCGTGGAGGGTGGTACAAGCTTAAAGAAGAATGAAGTGTTCCTGGTAAGCCTAA
GTGGCGTGGGGAGCTGGGTC

Downstream 100 bases:

>100_bases
CACGCTACAGCAGCCACGGCCTCGCCGTCACTATGTACCTAGACGGCTACCTGGTGAACGTGTGGCCAGTGCCTGGCTGG
TTTCCAGCTGCTAGCCGAGG

Product: adenylyl-sulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MERHGNAGLICLKRGIVAWLTGLPGSGKTTIARLAAEKLREMGYRVEHLDGDWVRKTINPDAGYTREERRRHLLRVAWIA
RLLARHGVIVLCSFVSPYRDVRREVREIVEAEGVPFIEVYVKCPVEECIKRDPKGLYRKALQGLIKHFTGVSDPYEPPEN
PDLELDTVSNTAEENAEKLVETILARLPRDKPG

Sequences:

>Translated_193_residues
MERHGNAGLICLKRGIVAWLTGLPGSGKTTIARLAAEKLREMGYRVEHLDGDWVRKTINPDAGYTREERRRHLLRVAWIA
RLLARHGVIVLCSFVSPYRDVRREVREIVEAEGVPFIEVYVKCPVEECIKRDPKGLYRKALQGLIKHFTGVSDPYEPPEN
PDLELDTVSNTAEENAEKLVETILARLPRDKPG
>Mature_193_residues
MERHGNAGLICLKRGIVAWLTGLPGSGKTTIARLAAEKLREMGYRVEHLDGDWVRKTINPDAGYTREERRRHLLRVAWIA
RLLARHGVIVLCSFVSPYRDVRREVREIVEAEGVPFIEVYVKCPVEECIKRDPKGLYRKALQGLIKHFTGVSDPYEPPEN
PDLELDTVSNTAEENAEKLVETILARLPRDKPG

Specific function: Catalyzes the synthesis of activated sulfate [H]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI46094058, Length=173, Percent_Identity=41.6184971098266, Blast_Score=141, Evalue=3e-34,
Organism=Homo sapiens, GI34447231, Length=170, Percent_Identity=40, Blast_Score=134, Evalue=7e-32,
Organism=Homo sapiens, GI62912492, Length=170, Percent_Identity=40, Blast_Score=133, Evalue=8e-32,
Organism=Escherichia coli, GI1789107, Length=174, Percent_Identity=41.9540229885057, Blast_Score=135, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17542422, Length=181, Percent_Identity=39.7790055248619, Blast_Score=143, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6322852, Length=171, Percent_Identity=41.5204678362573, Blast_Score=142, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24667040, Length=193, Percent_Identity=41.9689119170984, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24667032, Length=193, Percent_Identity=41.9689119170984, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24667028, Length=193, Percent_Identity=41.9689119170984, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24667036, Length=193, Percent_Identity=41.9689119170984, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI116007838, Length=193, Percent_Identity=41.9689119170984, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24667044, Length=193, Percent_Identity=41.9689119170984, Blast_Score=145, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891 [H]

Pfam domain/function: PF01583 APS_kinase [H]

EC number: =2.7.1.25 [H]

Molecular weight: Translated: 21920; Mature: 21920

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERHGNAGLICLKRGIVAWLTGLPGSGKTTIARLAAEKLREMGYRVEHLDGDWVRKTINP
CCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEECCCCCHHHHHHCCC
DAGYTREERRRHLLRVAWIARLLARHGVIVLCSFVSPYRDVRREVREIVEAEGVPFIEVY
CCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHH
VKCPVEECIKRDPKGLYRKALQGLIKHFTGVSDPYEPPENPDLELDTVSNTAEENAEKLV
EECCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHH
ETILARLPRDKPG
HHHHHHCCCCCCC
>Mature Secondary Structure
MERHGNAGLICLKRGIVAWLTGLPGSGKTTIARLAAEKLREMGYRVEHLDGDWVRKTINP
CCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEECCCCCHHHHHHCCC
DAGYTREERRRHLLRVAWIARLLARHGVIVLCSFVSPYRDVRREVREIVEAEGVPFIEVY
CCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHH
VKCPVEECIKRDPKGLYRKALQGLIKHFTGVSDPYEPPENPDLELDTVSNTAEENAEKLV
EECCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHH
ETILARLPRDKPG
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10382966 [H]