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The map label for this gene is ribB [H]

Identifier: 124027443

GI number: 124027443

Start: 533230

End: 533949

Strand: Direct

Name: ribB [H]

Synonym: Hbut_0558

Alternate gene names: 124027443

Gene position: 533230-533949 (Clockwise)

Preceding gene: 124027442

Following gene: 124027444

Centisome position: 31.98

GC content: 55.42

Gene sequence:

>720_bases
ATGGGCGAACTAGACAAGGCAATTGAGGCTATGCGGAAGGGTATCCCCGTCCTAATCCACGATGACTATGGTAGGGAGGA
CGAGGTAGACTATGTTATCCATGCATCCTACGTGACTGTCGACAAGATATATGAGATGAGAACCCTGGCAGGCGGCCTCA
TATGCTACGCTATGCCGCTACCAGCTGGTGAGATGCTTGGCCTCCGCTACATAGCCGACATACTTGCTGGTATCGAGCCT
CTTGGCAGGCTTGCAGAGCGCACCCTAGGCTACGGTGATAAGCCTGCCTTCTCGCTATGGGTTAACCATCTGAAGGCCAG
GACGGGGATACGGGACAGGGATAGGGCGCTCACAATACGCGAGCTGGACCGGGTTGTGAACCTCATATATTCTGGCAGGG
TTGAGGAGGCCCGTAAGCTATTCTACGAGAGCTTCATGGCGCCAGGTCATGTGCCGATACTGCTTGGAAGAAGGCTCGGG
GAGAGACGCGGTCACACCGAGCTATCCCTGCACCTTGCAATGCTTGCCGGGATGACACCGTCAACGGTTATCGTCGAGAT
GCTCGACCGTGGCGAGGCTTTGAGCGTGGAGGAGGCCCGCAGGGTATCTAGGGAGAAGGGCTACCCCCTGGTGGAGGGGA
GTGAGATTATAGCAGAGGTGGAGCGTCGTGGTGAAGATATGTATTGTCGATACAACCTTTGCAAGAATAGACATGGCTAG

Upstream 100 bases:

>100_bases
AGAGGCTCTTTACCCTCCCCACGGGAGGGGTGTGTAGTGCAGAACACTAAGGAGCGGCTTGGGCAGCAATGGAGACGTTT
CGCTTCGGGGGCGCAGCGTA

Downstream 100 bases:

>100_bases
GTATGCGATAGAGGTTCTCCAAAACCTCATGCCTGACGCAGTTATAGTCCGTAGGACGGTGCCGGGGATAAAGGACATCC
CGGTTGAGATCAAGACGCTG

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MGELDKAIEAMRKGIPVLIHDDYGREDEVDYVIHASYVTVDKIYEMRTLAGGLICYAMPLPAGEMLGLRYIADILAGIEP
LGRLAERTLGYGDKPAFSLWVNHLKARTGIRDRDRALTIRELDRVVNLIYSGRVEEARKLFYESFMAPGHVPILLGRRLG
ERRGHTELSLHLAMLAGMTPSTVIVEMLDRGEALSVEEARRVSREKGYPLVEGSEIIAEVERRGEDMYCRYNLCKNRHG

Sequences:

>Translated_239_residues
MGELDKAIEAMRKGIPVLIHDDYGREDEVDYVIHASYVTVDKIYEMRTLAGGLICYAMPLPAGEMLGLRYIADILAGIEP
LGRLAERTLGYGDKPAFSLWVNHLKARTGIRDRDRALTIRELDRVVNLIYSGRVEEARKLFYESFMAPGHVPILLGRRLG
ERRGHTELSLHLAMLAGMTPSTVIVEMLDRGEALSVEEARRVSREKGYPLVEGSEIIAEVERRGEDMYCRYNLCKNRHG
>Mature_238_residues
GELDKAIEAMRKGIPVLIHDDYGREDEVDYVIHASYVTVDKIYEMRTLAGGLICYAMPLPAGEMLGLRYIADILAGIEPL
GRLAERTLGYGDKPAFSLWVNHLKARTGIRDRDRALTIRELDRVVNLIYSGRVEEARKLFYESFMAPGHVPILLGRRLGE
RRGHTELSLHLAMLAGMTPSTVIVEMLDRGEALSVEEARRVSREKGYPLVEGSEIIAEVERRGEDMYCRYNLCKNRHG

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320695, Length=222, Percent_Identity=26.1261261261261, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422 [H]

Pfam domain/function: PF00926 DHBP_synthase [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 27018; Mature: 26887

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGELDKAIEAMRKGIPVLIHDDYGREDEVDYVIHASYVTVDKIYEMRTLAGGLICYAMPL
CCHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCEEEEECC
PAGEMLGLRYIADILAGIEPLGRLAERTLGYGDKPAFSLWVNHLKARTGIRDRDRALTIR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
ELDRVVNLIYSGRVEEARKLFYESFMAPGHVPILLGRRLGERRGHTELSLHLAMLAGMTP
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCH
STVIVEMLDRGEALSVEEARRVSREKGYPLVEGSEIIAEVERRGEDMYCRYNLCKNRHG
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEHHHCCCCC
>Mature Secondary Structure 
GELDKAIEAMRKGIPVLIHDDYGREDEVDYVIHASYVTVDKIYEMRTLAGGLICYAMPL
CHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCEEEEECC
PAGEMLGLRYIADILAGIEPLGRLAERTLGYGDKPAFSLWVNHLKARTGIRDRDRALTIR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
ELDRVVNLIYSGRVEEARKLFYESFMAPGHVPILLGRRLGERRGHTELSLHLAMLAGMTP
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCH
STVIVEMLDRGEALSVEEARRVSREKGYPLVEGSEIIAEVERRGEDMYCRYNLCKNRHG
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]