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The map label for this gene is ribD [C]

Identifier: 124027442

GI number: 124027442

Start: 532369

End: 533121

Strand: Direct

Name: ribD [C]

Synonym: Hbut_0557

Alternate gene names: 124027442

Gene position: 532369-533121 (Clockwise)

Preceding gene: 124027441

Following gene: 124027443

Centisome position: 31.93

GC content: 59.1

Gene sequence:

>753_bases
ATGACGCTGCGGAGGCCCTACACCGTCATATTCTCCACGATGACTCTTGACGGTCGCTTAGCATCATCGACGGGCTATAG
TGTGCTCAGCTGCCCATACGATTTCGCGCGGCTCCGCCTCCTCCGCGGCGCAGCAGACGCCGTGATGATAGGTGCCAATA
CGGCGCTTCTGGACGATCCCTCGCTACGCAAGAGACTTGAGCCTAGAAGCGAGAAGTACTACAGAGTAGTGGTTGACGGT
CGGCTCCGCATATCAGCGTCGCTGAGGCTGGTGCGCGAGCCTGAGCCGCCAGTGATAGTGTTTACAGCGGTTGAGTCACA
GCGAGCCAGGGAGTTAGAGGAGCGTGGCGTGAGGGTACATGTTGTCGGCTCTAACGGTGTAGTAGACCTTGCTAGGGCGC
TGGAGATACTAGCTGTAGAGTATGGTGTCGAGAGGCTCCTCGTGGAGGGTGGTGGGAGGCTCAACTATTCCCTGCTCTCG
AGCAGGCTTGTAGACGAGGTACGCGCAACGATAACACCCTACGTGTTCGCCGCTGGCCGGAGCTTCTTCGAGGACCCGGT
AGGTACTGGGTTCCGTGATACCCGCGAGTCGCCGAGGCTGCAGCTTGTCTGTACAGAGTTGTGCCCTTGTGGCCGCTGTG
TACACGTAGTCTACCGTGTAGTGGATAGACGTGGGGAGCCGCTAGCTAGCTCCCTAGTGGAGCCGTGTCTGTCCAGTAAG
CTCCGAGAGCTAGCTGCGAAGGGCCTCGTGTAG

Upstream 100 bases:

>100_bases
TGCGGAGCATTGGTGGCCGCAGAGTATTATTGGTGCCTGTTAGGACTACGGGAACCATTAAGAGGGCTAAGAAGGCGCTA
GCTGTTCCCAGGAGACTGCT

Downstream 100 bases:

>100_bases
CTAGCCATAGAGGCTCTTTACCCTCCCCACGGGAGGGGTGTGTAGTGCAGAACACTAAGGAGCGGCTTGGGCAGCAATGG
AGACGTTTCGCTTCGGGGGC

Product: pyrimidine reductase, riboflavin biosynthesis, RibD

Products: NA

Alternate protein names: HTP reductase [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MTLRRPYTVIFSTMTLDGRLASSTGYSVLSCPYDFARLRLLRGAADAVMIGANTALLDDPSLRKRLEPRSEKYYRVVVDG
RLRISASLRLVREPEPPVIVFTAVESQRARELEERGVRVHVVGSNGVVDLARALEILAVEYGVERLLVEGGGRLNYSLLS
SRLVDEVRATITPYVFAAGRSFFEDPVGTGFRDTRESPRLQLVCTELCPCGRCVHVVYRVVDRRGEPLASSLVEPCLSSK
LRELAAKGLV

Sequences:

>Translated_250_residues
MTLRRPYTVIFSTMTLDGRLASSTGYSVLSCPYDFARLRLLRGAADAVMIGANTALLDDPSLRKRLEPRSEKYYRVVVDG
RLRISASLRLVREPEPPVIVFTAVESQRARELEERGVRVHVVGSNGVVDLARALEILAVEYGVERLLVEGGGRLNYSLLS
SRLVDEVRATITPYVFAAGRSFFEDPVGTGFRDTRESPRLQLVCTELCPCGRCVHVVYRVVDRRGEPLASSLVEPCLSSK
LRELAAKGLV
>Mature_249_residues
TLRRPYTVIFSTMTLDGRLASSTGYSVLSCPYDFARLRLLRGAADAVMIGANTALLDDPSLRKRLEPRSEKYYRVVVDGR
LRISASLRLVREPEPPVIVFTAVESQRARELEERGVRVHVVGSNGVVDLARALEILAVEYGVERLLVEGGGRLNYSLLSS
RLVDEVRATITPYVFAAGRSFFEDPVGTGFRDTRESPRLQLVCTELCPCGRCVHVVYRVVDRRGEPLASSLVEPCLSSKL
RELAAKGLV

Specific function: Converts 2,5-Diamino-6-(Ribosylamino)-4(3h)-Pyrimidinone 5'-Phosphate Into 5-Amino-6-(Ribosylamino)-2,4(1h,3h)- Pyrimidinedione 5'-Phosphate. [C]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTP reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004794
- InterPro:   IPR006401
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF01872 RibD_C [H]

EC number: =1.1.1.193 [H]

Molecular weight: Translated: 27713; Mature: 27582

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRRPYTVIFSTMTLDGRLASSTGYSVLSCPYDFARLRLLRGAADAVMIGANTALLDDP
CCCCCCEEEEEEEEEECCEEECCCCCEEEECCHHHHHHHHHHCCCCEEEEECCEEEECCH
SLRKRLEPRSEKYYRVVVDGRLRISASLRLVREPEPPVIVFTAVESQRARELEERGVRVH
HHHHHCCCCCCCEEEEEECCEEEEEEEEEEEECCCCCEEEEEECCCHHHHHHHHCCCEEE
VVGSNGVVDLARALEILAVEYGVERLLVEGGGRLNYSLLSSRLVDEVRATITPYVFAAGR
EECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHHHHHHCC
SFFEDPVGTGFRDTRESPRLQLVCTELCPCGRCVHVVYRVVDRRGEPLASSLVEPCLSSK
HHHCCCCCCCCCCCCCCCCEEEEEHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LRELAAKGLV
HHHHHHHCCC
>Mature Secondary Structure 
TLRRPYTVIFSTMTLDGRLASSTGYSVLSCPYDFARLRLLRGAADAVMIGANTALLDDP
CCCCCEEEEEEEEEECCEEECCCCCEEEECCHHHHHHHHHHCCCCEEEEECCEEEECCH
SLRKRLEPRSEKYYRVVVDGRLRISASLRLVREPEPPVIVFTAVESQRARELEERGVRVH
HHHHHCCCCCCCEEEEEECCEEEEEEEEEEEECCCCCEEEEEECCCHHHHHHHHCCCEEE
VVGSNGVVDLARALEILAVEYGVERLLVEGGGRLNYSLLSSRLVDEVRATITPYVFAAGR
EECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHHHHHHCC
SFFEDPVGTGFRDTRESPRLQLVCTELCPCGRCVHVVYRVVDRRGEPLASSLVEPCLSSK
HHHCCCCCCCCCCCCCCCCEEEEEHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LRELAAKGLV
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8899719; 11427726 [H]