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The map label for this gene is hypA [H]

Identifier: 124027212

GI number: 124027212

Start: 305908

End: 306342

Strand: Direct

Name: hypA [H]

Synonym: Hbut_0315

Alternate gene names: 124027212

Gene position: 305908-306342 (Clockwise)

Preceding gene: 124027211

Following gene: 124027213

Centisome position: 18.35

GC content: 56.78

Gene sequence:

>435_bases
TTGCACGAGACAAGTATTGCCCTCAGCATACTTGCAGCAGTGGAGGATGTTTTCCGTTCCACACCTGGCGCTCGTAGGGT
CGAGAAGATACGGATACGCGTTGGGATGCTAAGCCTCGTGGATCCCGAGGCGCTAAGGTTTGCACTAAGCGTAGTATCCC
GCGACACTCCTGCGGAGAACGCTGAGGTAGAGATTGAGACTGTGAGGCCCCGGTTTCGCTGTCCCCACTGCGGCTACGAG
TGGGAGGTAGGTGACGAGGACGTCAAAAGGATAGCTGACGATCCTATGCTCGCCACGCTTGTCCACATACACCCCGACGT
TGTAGTCAAGTACCTCCGGTGCCCGCGCTGTGGCAGCACCGATGTGGAGATAGTTGAGGGGAAGGGTGTAGTGCTGCACA
GCGTAGTCATAGAGACAGACGAGGAAAAGGGGTAG

Upstream 100 bases:

>100_bases
TAAACCCCAAAGCGCCAATAGTGCTTGCCAGCGCGAAGACAGGGCAGGGCATTGACGAGCTATACCGTGTGCTCAAAAAG
TTTATGGTGAGGAGCTAGCC

Downstream 100 bases:

>100_bases
GGGAGAACTCCTTGGTGGTCAAGACTGGTGTCTCGCTACCCGACGAACTCTACGAGAAGCTTGTCTCCCTAGCCCAGCGC
GCGGGCTACCCGAGTATCTC

Product: hydrogenase expression/synthesis hypA family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MHETSIALSILAAVEDVFRSTPGARRVEKIRIRVGMLSLVDPEALRFALSVVSRDTPAENAEVEIETVRPRFRCPHCGYE
WEVGDEDVKRIADDPMLATLVHIHPDVVVKYLRCPRCGSTDVEIVEGKGVVLHSVVIETDEEKG

Sequences:

>Translated_144_residues
MHETSIALSILAAVEDVFRSTPGARRVEKIRIRVGMLSLVDPEALRFALSVVSRDTPAENAEVEIETVRPRFRCPHCGYE
WEVGDEDVKRIADDPMLATLVHIHPDVVVKYLRCPRCGSTDVEIVEGKGVVLHSVVIETDEEKG
>Mature_144_residues
MHETSIALSILAAVEDVFRSTPGARRVEKIRIRVGMLSLVDPEALRFALSVVSRDTPAENAEVEIETVRPRFRCPHCGYE
WEVGDEDVKRIADDPMLATLVHIHPDVVVKYLRCPRCGSTDVEIVEGKGVVLHSVVIETDEEKG

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step [H]

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000688
- InterPro:   IPR020538 [H]

Pfam domain/function: PF01155 HypA [H]

EC number: NA

Molecular weight: Translated: 16047; Mature: 16047

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHETSIALSILAAVEDVFRSTPGARRVEKIRIRVGMLSLVDPEALRFALSVVSRDTPAEN
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEHHHHHCCHHHHHHHHHHHHCCCCCCC
AEVEIETVRPRFRCPHCGYEWEVGDEDVKRIADDPMLATLVHIHPDVVVKYLRCPRCGST
CEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHCHHHHHHHHHCCCCCCC
DVEIVEGKGVVLHSVVIETDEEKG
CEEEEECCCEEEEEEEEECCCCCC
>Mature Secondary Structure
MHETSIALSILAAVEDVFRSTPGARRVEKIRIRVGMLSLVDPEALRFALSVVSRDTPAEN
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEHHHHHCCHHHHHHHHHHHHCCCCCCC
AEVEIETVRPRFRCPHCGYEWEVGDEDVKRIADDPMLATLVHIHPDVVVKYLRCPRCGST
CEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHCHHHHHHHHHCCCCCCC
DVEIVEGKGVVLHSVVIETDEEKG
CEEEEECCCEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]