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The map label for this gene is hypB [H]

Identifier: 124027211

GI number: 124027211

Start: 305225

End: 305905

Strand: Direct

Name: hypB [H]

Synonym: Hbut_0314

Alternate gene names: 124027211

Gene position: 305225-305905 (Clockwise)

Preceding gene: 124027210

Following gene: 124027212

Centisome position: 18.31

GC content: 52.57

Gene sequence:

>681_bases
ATGGTTAAAGCCGTCCGGTTCCTTGGAAAGGACATAATCAAGGAGAATGCACGGCTTGCAGAGAGGCTCCGGAAGCTCTA
CGACGAGGCTGGTGTAACTGTCTATGAGTTCCTCGGGGGTCCAGGCAGCGGAAAGACCAGTGTTATAGAGAGACTCGTGG
AGAAGATGCTCGAGGAGTACCGGCCCGAGGAGATAGCCTACATAGGCGGCGATATAGCAACAACACTTGACACCGAGAGG
ATAGCCAGATACGGTGTAAGACACGTACAGATCAATACTGGTGGCACATGCCACCTAGAAGTCCCCCATGTTGAGGCGGC
GATAAAGGCACTAGGGGGCTCCGAGGCTCTCCACAAGCTCCGCATAATGATAATAGAGAATGTTGGGAACCTCATATGCC
CATTTAACTTCCCCCTCGGAGCCCATGCAAGAATAATGGTGGCCGATGTCACTGAGGGCGAGGACAAGTTTGTAAAGCAT
CCGCTCAGCACGAAGGTGAGCGATGTCATAGTAATAAACAAGGTTGACCTTGCACCCATAGTGGGTGTAAACCTCGAGAA
GATGGTCAGCGATGCCCGCACCCTAAACCCCAAAGCGCCAATAGTGCTTGCCAGCGCGAAGACAGGGCAGGGCATTGACG
AGCTATACCGTGTGCTCAAAAAGTTTATGGTGAGGAGCTAG

Upstream 100 bases:

>100_bases
CTCTACTTGATAGGGTTGCTGCACACGCTGCTACCGGTGTTCTTTAGCATTTTTAACCTCGTTTATGAACACCGGTTCTC
AGGGAGAGGTGCACCCGCAT

Downstream 100 bases:

>100_bases
CCTTGCACGAGACAAGTATTGCCCTCAGCATACTTGCAGCAGTGGAGGATGTTTTCCGTTCCACACCTGGCGCTCGTAGG
GTCGAGAAGATACGGATACG

Product: hydrogenase/urease nickel incorporation protein, GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MVKAVRFLGKDIIKENARLAERLRKLYDEAGVTVYEFLGGPGSGKTSVIERLVEKMLEEYRPEEIAYIGGDIATTLDTER
IARYGVRHVQINTGGTCHLEVPHVEAAIKALGGSEALHKLRIMIIENVGNLICPFNFPLGAHARIMVADVTEGEDKFVKH
PLSTKVSDVIVINKVDLAPIVGVNLEKMVSDARTLNPKAPIVLASAKTGQGIDELYRVLKKFMVRS

Sequences:

>Translated_226_residues
MVKAVRFLGKDIIKENARLAERLRKLYDEAGVTVYEFLGGPGSGKTSVIERLVEKMLEEYRPEEIAYIGGDIATTLDTER
IARYGVRHVQINTGGTCHLEVPHVEAAIKALGGSEALHKLRIMIIENVGNLICPFNFPLGAHARIMVADVTEGEDKFVKH
PLSTKVSDVIVINKVDLAPIVGVNLEKMVSDARTLNPKAPIVLASAKTGQGIDELYRVLKKFMVRS
>Mature_226_residues
MVKAVRFLGKDIIKENARLAERLRKLYDEAGVTVYEFLGGPGSGKTSVIERLVEKMLEEYRPEEIAYIGGDIATTLDTER
IARYGVRHVQINTGGTCHLEVPHVEAAIKALGGSEALHKLRIMIIENVGNLICPFNFPLGAHARIMVADVTEGEDKFVKH
PLSTKVSDVIVINKVDLAPIVGVNLEKMVSDARTLNPKAPIVLASAKTGQGIDELYRVLKKFMVRS

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=210, Percent_Identity=37.6190476190476, Blast_Score=137, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 24858; Mature: 24858

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKAVRFLGKDIIKENARLAERLRKLYDEAGVTVYEFLGGPGSGKTSVIERLVEKMLEEY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHH
RPEEIAYIGGDIATTLDTERIARYGVRHVQINTGGTCHLEVPHVEAAIKALGGSEALHKL
CCCCEEEECCCHHHHHHHHHHHHHCCEEEEEECCCEEEEECCHHHHHHHHCCCHHHHHHH
RIMIIENVGNLICPFNFPLGAHARIMVADVTEGEDKFVKHPLSTKVSDVIVINKVDLAPI
HHHHHHCCCCEEECCCCCCCCCCEEEEEECCCCCHHHHHCCCCCCCCCEEEEECCCCCCC
VGVNLEKMVSDARTLNPKAPIVLASAKTGQGIDELYRVLKKFMVRS
CCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVKAVRFLGKDIIKENARLAERLRKLYDEAGVTVYEFLGGPGSGKTSVIERLVEKMLEEY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHH
RPEEIAYIGGDIATTLDTERIARYGVRHVQINTGGTCHLEVPHVEAAIKALGGSEALHKL
CCCCEEEECCCHHHHHHHHHHHHHCCEEEEEECCCEEEEECCHHHHHHHHCCCHHHHHHH
RIMIIENVGNLICPFNFPLGAHARIMVADVTEGEDKFVKHPLSTKVSDVIVINKVDLAPI
HHHHHHCCCCEEECCCCCCCCCCEEEEEECCCCCHHHHHCCCCCCCCCEEEEECCCCCCC
VGVNLEKMVSDARTLNPKAPIVLASAKTGQGIDELYRVLKKFMVRS
CCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]