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The map label for this gene is umuD [H]

Identifier: 123966252

GI number: 123966252

Start: 911002

End: 911433

Strand: Direct

Name: umuD [H]

Synonym: P9515_10191

Alternate gene names: 123966252

Gene position: 911002-911433 (Clockwise)

Preceding gene: 123966251

Following gene: 123966253

Centisome position: 53.46

GC content: 28.01

Gene sequence:

>432_bases
ATGTACTATATAAAAATGCATTCTTCTGATTTGACTTTTAAAAAGGTGAAAATTCCATTATTAAGTGATTCGGTCTCAGC
AGGTTTCCCATCTCCTGCAGATGACTATACTGAGGAAAATATTGATTTGAATGAGCATTTAATATCTAATCCTTTTAGTA
CTTTTTTTCTTAGAGTTAAAGGTGACTCAATGATAAATTCAGGAATTAAAGATAAAGATTTAATAATAGTAGATAAGAGT
TTAACTGCTAAACCAGGGAATATCATCATTGCGATGATAGATGGAGAATTTACAATAAAAAGATTATCTATAAGAAATAA
TGAATTATATTTAAAAGCAGAAAATCATAATTACCCGGACTTCAGTTTTAGGAATCATGTTGATATACAGATTTGGGGAG
TTGTAATTTATTCAATACATAGTTACTTATGA

Upstream 100 bases:

>100_bases
CTAATGGTTCGCCTTACCATCGTGCCTAAAGAGAAAATTTAAAATTATTATATAAAATCTTAAAACAGACACAATTTCAA
TATTTTAATATATAGTATAT

Downstream 100 bases:

>100_bases
AAAGCAAAAGCTCAATTACTGAAGCAATAGCTCTCATAGATGCTAATAATTTTTACGCATCATGCGAACAAAGTATTAAT
CCACATTTAAGGAATAAACC

Product: putative SOS mutagenesis protein UmuD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MYYIKMHSSDLTFKKVKIPLLSDSVSAGFPSPADDYTEENIDLNEHLISNPFSTFFLRVKGDSMINSGIKDKDLIIVDKS
LTAKPGNIIIAMIDGEFTIKRLSIRNNELYLKAENHNYPDFSFRNHVDIQIWGVVIYSIHSYL

Sequences:

>Translated_143_residues
MYYIKMHSSDLTFKKVKIPLLSDSVSAGFPSPADDYTEENIDLNEHLISNPFSTFFLRVKGDSMINSGIKDKDLIIVDKS
LTAKPGNIIIAMIDGEFTIKRLSIRNNELYLKAENHNYPDFSFRNHVDIQIWGVVIYSIHSYL
>Mature_143_residues
MYYIKMHSSDLTFKKVKIPLLSDSVSAGFPSPADDYTEENIDLNEHLISNPFSTFFLRVKGDSMINSGIKDKDLIIVDKS
LTAKPGNIIIAMIDGEFTIKRLSIRNNELYLKAENHNYPDFSFRNHVDIQIWGVVIYSIHSYL

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S24 family [H]

Homologues:

Organism=Escherichia coli, GI1787431, Length=141, Percent_Identity=44.6808510638298, Blast_Score=121, Evalue=2e-29,
Organism=Escherichia coli, GI1790476, Length=101, Percent_Identity=36.6336633663366, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006197
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 16375; Mature: 16375

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYYIKMHSSDLTFKKVKIPLLSDSVSAGFPSPADDYTEENIDLNEHLISNPFSTFFLRVK
CEEEEEECCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEEEEEEE
GDSMINSGIKDKDLIIVDKSLTAKPGNIIIAMIDGEFTIKRLSIRNNELYLKAENHNYPD
CCHHHCCCCCCCEEEEECCCCCCCCCCEEEEEECCCEEEEEEEECCCEEEEEECCCCCCC
FSFRNHVDIQIWGVVIYSIHSYL
CCCCCEEEEEEEEEEEEEHHHCC
>Mature Secondary Structure
MYYIKMHSSDLTFKKVKIPLLSDSVSAGFPSPADDYTEENIDLNEHLISNPFSTFFLRVK
CEEEEEECCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEEEEEEE
GDSMINSGIKDKDLIIVDKSLTAKPGNIIIAMIDGEFTIKRLSIRNNELYLKAENHNYPD
CCHHHCCCCCCCEEEEECCCCCCCCCCEEEEEECCCEEEEEEEECCCEEEEEECCCCCCC
FSFRNHVDIQIWGVVIYSIHSYL
CCCCCEEEEEEEEEEEEEHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]